the research on schizophrenia

Although schizophrenia is a complex syndrome that is difficult to manage, recent advances in ongoing research studies and clinical trials are contributing to the management of schizophrenia. Investigating the neurobiological processes behind behavioral disorders, including schizophrenia, will facilitate a better understanding of the ...

The scope of this practice guideline is shaped by the Treatments for Schizophrenia in Adults (McDonagh et al. 2017), a systematic review that was commissioned by the Agency for Healthcare Research and Quality (AHRQ) and that serves as a principal source of information for the guideline. The AHRQ review uses the DSM-5 definition of schizophrenia ...

Genes. One area of research that's shown progress is the role of genes. Scientists recently published the largest-ever whole-genome sequencing (WGS) study of schizophrenia. WGS is a technology ...

1. INTRODUCTION. This paper reports a review of outcomes in schizophrenia in the twenty‐first century and is an extension of the work undertaken by the late Dr Richard Warner in his seminal book, "Recovery from Schizophrenia: Psychiatry and Political Economy" (1985 (Warner, 1985); 2004 (Warner, 2004)).The present work was started with Dr Warner's involvement, and the preliminary results ...

Schizophrenia. Schizophrenia is a psychiatric syndrome characterized by psychotic symptoms of hallucinations, delusions, and disorganized speech, by negative symptoms such as decreased motivation ...

Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor. A division of symptoms into positive, negative, and disorganisation syndromes is supported by factor analysis.

The new research focused on identifying a new approach that would treat positive and negative symptoms, Maksymetz said. Schizophrenia is thought to occur when a region of the brain called the ...

Schizophrenia is a severe and debilitating psychiatric disorder that involves psychotic symptoms such as hallucinations and delusions, accompanied with regressive behaviour. Latest Research and ...

For this study, the research team analyzed postmortem tissue samples from 443 donors, which included adults who had either a schizophrenia or bipolar diagnosis and healthy controls with no known history of mental illnesses. The donors reflected a diverse mix of ancestries.

An International Multidisciplinary Journal of the Schizophrenia International Research Society. As official journal of the Schizophrenia International Research Society (SIRS) Schizophrenia Research is THE journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community. More than 6000 institutes have online or print (or both ...

Schizophrenia has been conceptualized as a disorder of brain connectivity since the illness was first defined (9, 10, 44), ... Thus, research efforts that target the second decade of life are essential if we are to find mechanisms for intervention and cure. These studies are costly and time-consuming, but there is an example that is rapidly ...

Schizophrenia Spectrum Disorders (SSD) are severe conditions that frequently produce significant impairment in cognitive performance, social skills and psychosocial functioning. ... Future research should focus on developing newer interventions, on better understanding the barriers and the facilitators of their implementation in clinical ...

However, research shows that gradual changes in thinking, mood, and social functioning often appear before the first episode of psychosis. Schizophrenia is rare in younger children. Schizophrenia symptoms can differ from person to person, but they generally fall into three main categories: psychotic, negative, and cognitive. Psychotic symptoms

Schizophrenia research is providing an increasing number of studies and important insights into the condition's etiopathogenesis based on genetic, neuropsychological and cranial neuroimaging studies. However, research progress has not yet led to the incorporation of such findings into the revised classification criteria of mental disorders or ...

Beginning in 1987, the Brain & Behavior Research Foundation was providing seed money to neuroscientists to invest in "out of the box" research that the government and other sources were unwilling to fund. Today, Brain & Behavior Research Foundation is still the leading, private philanthropy in the world in this space.

Causes of schizophrenia. Research has not identified one single cause of schizophrenia. It is thought that an interaction between genes and a range of environmental factors may cause schizophrenia. Psychosocial factors may also affect the onset and course of schizophrenia. Heavy use of cannabis is associated with an elevated risk of the disorder.

Benedict Carey January 27, 2016. Scientists reported that they had taken a significant step toward understanding the cause of schizophrenia, in a landmark study that provides the first rigorously tested insight into the biology behind any common psychiatric disorder. Steven McCarroll (HMS) led the study. Read the full article. Additional coverage:

Schizophrenia is a serious mental health condition that affects how people think, feel and behave. It may result in a mix of hallucinations, delusions, and disorganized thinking and behavior. Hallucinations involve seeing things or hearing voices that aren't observed by others. ... many research studies have examined the results of untreated ...

Schizophrenia is a debilitating mental illness which involves three groups of symptoms, i.e., positive, negative and cognitive, and has major public health implications. According to various sources, it affects up to 1% of the population. ... Changes in the GABA neurotransmission were found in basic and clinical research on schizophrenia and in ...

Schizophrenia is a severe psychiatric disorder that imposes a considerable burden on patients, their families, and society as a whole ().The fact that the burden of schizophrenia is compounded by the insufficient efficacy of available treatment options has motivated a wide range of clinical and pre-clinical research endeavors.

However, research shows that gradual changes in thinking, mood, and social functioning often appear before the first episode of psychosis. Schizophrenia is rare in younger children. Schizophrenia symptoms can differ from person to person, but they generally fall into three main categories: psychotic, negative, and cognitive.

Schizophrenia is a complex brain disorder. It often runs in families and can cause troubling symptoms. It's caused by a chemical imbalance and other changes in the brain. Symptoms include hearing voices, feeling that people are out to get you, and having false beliefs that are not based in reality. These symptoms can make it very hard to ...

Right after a trip I took to Italy, I found myself on the inside of a psychiatric ward. This was the first time I checked myself into a psychiatric facilit

Presents case report of brexpiprazole-related tardive dystonia. Tardive dystonia, a syndrome marked by continuous muscle contractions resulting in twisting, repetitive movements, or unusual postures, is a type of extrapyramidal symptoms (EPS) often developing after prolonged use of neuroleptics. Brexpiprazole, an atypical antipsychotic acting as a partial agonist at dopamine D2 and serotonin 5 ...

Schizophrenia is a disabling psychiatric condition impacting around 1% of people worldwide and ranking among the top 10 global disability causes.[1] Schizophrenia is characterized by positive psychotic symptoms such as hallucinations, delusions, disorganized speech, and disorganized or catatonic behavior; negative symptoms such as reduced motivation and expressiveness; and cognitive ...

Last month, Maryland Health Secretary Dr. Laura Herrera Scott shut down a first-of-its-kind inpatient study that's shown promise for treating schizophrenia. On behalf of the patients who volu…

Poland: Poland's Celon Pharma believes its experimental treatment for acute schizophrenia could eventually achieve annual sales in the billions of dollars, Chief Executive Maciej Wieczorek said on Wednesday. Last Friday, the company said the drug achieved favourable results in the second phase of clinical studies, showing high efficacy and good tolerance among patients.

Schizophrenia prodrome, sometimes referred to as ultra-high-risk state or psychosis risk syndrome, is thought to be a spectrum of attenuated positive and negative symptoms that individuals may display several years to months before converting to schizophrenia. Recent research has begun to elucidate risk factors for conversion to psychosis ...

In a report released today, Anupam Rama from J.P. Morgan maintained a Buy rating on Neurocrine (NBIX - Research Report), with a price target of $173.00. Anupam Rama has given his Buy rating due ...