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Minneapolis Medical Research Foundation

The Minneapolis Medical Research Foundation (MMRF), has been finding answers to the health problems of our patients since 1952. Operating in Hennepin County Medical Center (HCMC), an acute care research and teaching hospital, we support and oversee the medical research that takes place on campus. In an academic environment that emphasizes patient care, research and teaching, MMRF helps offer patients better care now and hope for improved healthcare in the future. We have research programs in alternative medicine, brain and immune disorders, cancer, clinical outcomes, children’s research and child advocacy, foods for well-being, heart disease, HIV/AIDS, international medicine, liver and gastrointestinal disease, orthopaedics, renal data studies, sleep disorders, tobacco dependence, trauma and burn, and traumatic brain injury.

Mayo Clinic Research in Minnesota

Scientists and physicians in Minnesota conduct innovative research across the spectrum of medicine, translating their discoveries into new treatments that benefit patients. Knowing that teamwork improves and speeds discovery, researchers collaborate with fellow scientists nationally and internationally as they mentor the next generation of researchers.

"Only through discovery and innovation will we advance patient care." Gregory J. Gores, M.D. Kinney Executive Dean for Research Mayo Clinic Mayo Clinic in Minnesota

Researchers

To improve patient care, scientists and physicians in Minnesota conduct research in nearly every field of medicine. From basic science studies to clinical trials and beyond, researchers in laboratories, centers and programs collaborate to find answers to medicine's most difficult questions.

Core Resources

Institutional core resources ─ shared scientific facilities ─ offer investigators specialized services, technical support, and cost-effective access to resources to expand capabilities, foster collaboration and accelerate discovery.

Labs, Centers and Programs

In support of research, laboratories, centers and programs often offer resources, training opportunities and funding to researchers. Some research centers are disease focused, while others provide infrastructure that supports and facilitates research of all types.

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Clinical Trials in Minnesota

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CDRG Re-Awarded United States Renal Data System (USRDS) Federal Contract

CDRG Releases 2023 USRDS Annual Data Report

Read report highlights in the announcement.

Read about the latest research in our areas of expertise.

An in-depth look at kidney disease.

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What do we do?

Our team comprise s biostatisticians, epidemiologists, physician investigators, medical writers, and so much more. Employing our vast expertise in healthcare research studies, we conduct observational, clinical , and epidemiological studies into chronic diseases and examine long - and short-term patient outcomes, patterns of care, important changes in clinical practice, and implications for health economics and policy. Because we d edicat e these research strategies to every project we take on, your project gets the attention and effort it needs. When it comes to your work, we deliver .

 Featured Program Areas

The study of kidney disease epidemiology has been a core mission of CDRG for over two decades. 

Our research in oncology has provided valuable insights into the incidence, treatment, and effects of cancer. 

Transplantation

Our transplantation team provides quality analytics and consulting for all our partners in the field of transplantation.

Typical Deliverables

From start to finish , we strive to exceed expectations, with communication being the key to successful collaboration. Whatever the size of the project, we will work with you to determine your needs and the most useful format and method of data presentation, to help you meet your objectives.

The Chronic Disease Research Group (CDRG) is a division of the Hennepin Healthcare Research Institute (EIN 1568208), located in Minneapolis, MN.

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Clinical Research Internship Program

Developing and empowering the next generation of cardiovascular health professionals through a cutting-edge research internship program.

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• Meet The Interns

Educating the Next Generation

The Minneapolis Heart Institute Foundation® (MHIF) offers one of the most outstanding and unique internship opportunities available to undergraduates who are pre-med or planning a career in medicine. The goal of the research internship program is to develop and empower the next generation of cardiovascular health professionals by offering a robust research experience in the field of cardiology.

During this unique educational experience, the research intern is paired with a physician mentor who is actively engaged as a clinician and researcher at a nationally recognized hospital. At the conclusion of the program, the interns will showcase their research work at an open house and poster session. Many projects result in the intern having the opportunity to be an author on an article published in a national scientific journal. Some interns also have the opportunity to present their work at a national cardiovascular conference.

This internship is made possible thanks to philanthropic support from generous donors.

Research Internship Details

Research Internship Overview

Be a part of the Minneapolis Heart Institute Foundation’s exceptional 12-week cardiovascular clinical research internship designed for undergraduate students who are pre-med or planning a career in medicine. During this unique educational experience you will be paired with a physician mentor who is actively engaged as a clinician and researcher at a nationally recognized hospital. You will have the opportunity to:

• Participate in groundbreaking cardiovascular research
• Shadow a physician mentor in hospital rounds, watch procedures and listen as care teams discuss cases.
• Observe an open-heart procedure.
• Attend case conferences where cross-functional care teams discuss difficult cases.
• Shadow cardiovascular nurses in the ICU and post-surgical care area.
• Observe leading-edge cardiovascular diagnostic services.
• Reflect on your career options while hearing physicians’ candid stories of career journeys and passions during lunch and learns.
• Participate in interactive medical device industry tours and a hands-on tour of cardiovascular specimens at a nationally renowned heart registry.

At the conclusion of the internship, you will showcase your research work at an open house and poster session. Many projects result in the intern having the opportunity to be an author on an article published in a national scientific journal. Some interns will also have the opportunity to present their work at a national cardiovascular conference.

Location:  On the campus of the flagship hospital of Allina Health, Abbott Northwestern Hospital, in Minneapolis, Minnesota.

Program dates:  May 22 - August 9, 2024

Compensation:  A $550 per week stipend paid bi-weekly to assist with expenses for housing and living expenses (no direct housing provided). Scholarship opportunities may be available for accepted applicants who need further support for travel or living expenses.

Application Opens: November 10, 2023

Deadline: January 3, 2024

Selection Notification: March 4, 2024

Program Dates: May 22 - August 9, 2024

Eligibility

• Undergraduate or recent graduate from a four-year college and not yet accepted to medical school. Preference will be given to those who have completed their junior year by the start of the research internship. Strong applicants who have completed their sophomore year or just graduated from college may also be considered.
• Must be enrolled in or a very recent graduate from an accredited degree program and not yet accepted to medical school.
• GPA of 3.60 or above.
• Applicants must be US citizens or have Permanent Resident status (be able to provide proof of employability through completion of the I-9 Form).
• The program welcomes applicants from all backgrounds, including but not limited to BIPOC (Black, Indigenous, People of Color) individuals, individuals who are historically underrepresented in health-related sciences and medical fields, individuals who face greater obstacles to educational achievements and individuals who can contribute to diversity, equity and inclusion efforts in the health-related sciences and medical fields.
• Must be able to complete 8-12 hours of independent, online CITI training (basic training required to participate in human subjects/clinical research) by April 30.
• Available to participate full-time (at least 40 hours per week) in the internship May 22 through August 9, 2024.

Steps Before You Apply

• Review the sample  application PDF  and prepare responses to the short answer and essay questions. Please note: this is an example and the application for the next cohort may change.
• Write a personal motivation statement (3,500 characters including spaces).
• Prepare a one-page resume (save as PDF or Word doc with file name First Name_Last Name).
• Note that you will have the opportunity to make changes to your application before submitting.

Program Components

In preparing for a career in medicine, this experience will position you well through a unique opportunity to participate in cardiovascular clinical research, shadow clinicians in action and witness everything from a routine day to extraordinary life-saving procedures.

• Orientation:  Three days of orientation will prepare you for your research project, ground you in cardiovascular essentials and introduce you to the colleagues you will be working with, including your research physician, staff mentor and fellow interns.
• Research project:  You will be paired with a physician who is the Principal Investigator on a research project and a staff mentor. In addition to capturing data from the electronic health record, organizing and analyzing the data and preparing conclusions, you may also write case reports and support other research projects.
• Observations:  To provide you with exposure to what a career is really like in the field of medicine, you will observe various cardiovascular procedures, shadow healthcare professionals and visit cardiovascular related departments at Abbott Northwestern Hospital. Additionally, interns shadow healthcare professionals in the ICU and post-procedural care areas.
• Field Trips:  Minneapolis is a hub for headquarters of major medical device companies and start-ups. You will have custom tours of some major medical device companies, the renowned Visible Heart Lab at the University of Minnesota and the Jesse E. Edwards Registry of Cardiovascular Disease. This registry is a repository for heart specimens of almost every known type of heart disease, including rare congenital and adult heart diseases.
• Poster Session:  The culminating event of the research internship program, you will display your outcomes on a research poster and present to mentors, other medical professionals, MHIF board members, family and friends.
• Cohort Activities:  The internship draws talent from across the country. Many interns gain friends for life through their summer experience in Minneapolis. In addition to MHIF-organized activities, interns plan activities for the weekends. Past interns have enjoyed camping, hiking, canoeing, BBQs and exploring the Twin Cities of Minneapolis and St. Paul.

Frequently Asked Questions

How many applications do you typically receive? 150-250 each year.

How many research interns are accepted? 7-9 new interns plus one lead intern from the previous cohort.

Should I apply if my GPA is below 3.6? A 3.6 GPA or above is highly preferred. The application has a space to explain extenuating circumstances.

Is a social security number (SSN) required to participate in this research internship? Yes, a SSN is required by the US Internal Revenue Service of all employers who report wages (stipend). Further information regarding SSNs can be found on the  Social Security fact page .

Can I submit a letter of recommendation with my application? No. The online application with an attached resume are the accepted items.

The academic calendar for my school ends after Memorial Day or starts before the research internship program ends. Can I still apply? Interns are to be available to participate full-time in the internship from May 22 through August 9, 2024 with the first three days of orientation being key to a successful internship. Explain your circumstances in the eligibility section for consideration.

I anticipate attending summer classes. Can I still apply? This research internship is a full-time endeavor. It is not advised to apply.

What are the typical days/hours for this internship? What if I have a conflict? The internship program begins May 22 and ends August 9. MHIF is closed on May 27 for Memorial Day, June 19 and July 4. If interns have an important conflict, it should be pre-approved and should be limited to no more than 1-2 business days during the internship.

Core intern work days/hours are Monday to Friday from 7:30 am to 4:00 pm. Projects may require additional hours as deadlines approach. There are also some evening events or early morning observations.

I will be applying to medical school or doing medical school interviews during the summer. Can I still apply? Completing medical school applications is acceptable and needs to be completed outside of the research internship work hours. Attending medical school interviews are possible as long as the intern fulfills the expectations for the internship, which can require additional hours over and above scheduled work hours.

What statistical and software skills are needed? Interns will be using statistical software (including R), Excel, Word, and PowerPoint to build and maintain data dictionaries, do data cleaning, data validation, data verification, and work with demographic data. While some training will be provided, a working knowledge of these tools will be helpful.

Do you provide housing support? Generally we are not able to offer housing support. However, we share intern contact information for roommate collaborations and recommend researching the University of Minnesota campus (approximately two miles away), Facebook and Craigslist for short-term rental or sublet options. Scholarship opportunities may be available for accepted applicants who need housing/transportation support.

Can I apply again, if I am not selected this time? Yes, as long as you still meet the eligibility requirements.

Where can send a question if my question is not answered here? Email   [email protected]

2024 Internship Application

Applications for the 2024 internship are closed. Applications for the 2025 cohort will open in November - keep watch for more details.

Cheers to 20 Years of Interns!

During the past 20 years, 235 clinical research interns have contributed to 223 posters and presentations at national scientific sessions, 219 publications in peer-reviewed journals, and 59% of former interns are now practicing physicians !

In celebration of this 20-year landmark, we were excited to reconnect with Dr. Aaron Tande, MD , who was part of our first internship program in 2002 . Hear what Aaron has to say about his internship experience 20 years later:

Intern Program Highlights

Since 2002, 235 research interns have contributed to….

223 posters and presentations at national scientific sessions

219 publications in peer-reviewed journals

Where are they now.

59% are physicians

24% are in medical school

12% are in healthcare related fields

5% are in non-healthcare fields

Intern Experience

During the summer research internship, interns will be exposed to a vast array of clinical research and educational experiences. They will be matched with a physician and staff mentor, who will guide them through a clinical research project throughout the summer. This valuable exposure takes place at a nationally ranked and award-winning hospital, Abbott Northwestern Hospital in Minneapolis, Minnesota.

In addition to many observations of surgery and procedures in the hospital, interns will embark on several field trips to destinations including the University of Minnesota Heart Lab, medical device companies and research organizations. Weekly Lunch and Learn presentations from the renowned cardiologists at the Minneapolis Heart Institute® and other guest speakers will offer exposure to the wide range of research happening at MHIF and unique career paths.

Meet Our Interns

Meet our 2024 Interns >

Meet our 2023 Interns >

Meet our 2022 Interns >

Meet our 2021 Interns >

Meet our 2020 Interns >

Meet our 2019 Interns >

2024 Intern Program Donors

This cutting-edge educational experience is made possible by the generous contributions of individual donors, local foundations and industry organizations who share in the belief that hands-on experience is critical for tomorrow’s leaders. Financial support from donors means interns can work with both a staff and a physician mentor to learn about the research process and cardiology.

Thank you to the following generous donors for their contributions to the 2024 MHIF Internship Program:

Support the Intern Program

Help fund the next generation of cardiovascular experts!

The Minneapolis Heart Institute Foundation® (MHIF) strives to create a world without heart and vascular disease. To achieve this bold vision, we are dedicated to improving the cardiovascular health of individuals and communities through innovative research and education.

Thanks to the generosity of donors like you , we can continue this life-saving work. Please make a gift to support the area of greatest need.

All Gifts Matched! Educating the Next Generation of Heart Heroes

Since 2002, MHIF's Clinical Research Internship Program has hosted 235+ students for a unique physician-mentored cardiovascular research internship for undergraduate students. Interns not only gain exceptional experience that helps them prepare for medical school, they also help move MHIF research forward.

Community support is key to our ability to enlist the highest level of talent with annual internship costs exceeding $25,000 per intern. Build new opportunities for the next generation of world-class physician researchers by making a MATCHED gift by May 31st!

Minneapolis Medical Research Foundation

701 Park Ave. , Minneapolis , Minnesota 55415

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Berman Center for Clinical Outcomes and Research

Home » Our Research » Berman Center for Clinical Outcomes and Research

The Berman Center: Comprehensive Research Services Support

Since its founding in 1966 by Dr. Reuben Berman, a pioneer in cardiovascular clinical research, The Berman Center for Outcomes and Clinical Research, in Minneapolis, MN, has achieved an international reputation for conducting clinical research. The Berman Center is known for studies in NIH-funded cardiovascular research, diabetes (ACCORD) and women’s health issues (WHI) -- under Dr. Richard Grimm -- and more recently for work on dementia and aging, chronic kidney disease (CKD) and cognitive impairment, under Berman Center Medical Director Dr. Anne Murray. We serve as the North Star Node for multiple addiction medicine trials (Dr. Gavin Bart), and many other CKD and dialysis disease studies (Dr. Kirsten Johansen). Over the past 10 years the volume of studies has grown substantially

The Berman Center supports the research mission of Hennepin Health Research Institute (HHRI) and Hennepin Health System (HHS), by serving as its primary clinical site for over 100 clinical trials and observational studies, and national coordinating center for multiple large trials. The Berman Center supports the research mission of Hennepin Health Research Institute (HHRI, founded in 1952), the third largest nonprofit medical research institution in the state of Minnesota. HHRI operates within Hennepin Healthcare, an integrated system of care that includes a nationally recognized Level I Adult and Pediatric Trauma Center, a 484-bed academic hospital, and primary care clinics. Hennepin Healthcare is the largest public hospital in Minnesota. The system is operated by Hennepin Healthcare System, a subsidiary corporation of Hennepin County.

The Berman Center provides comprehensive research services support .

Our experienced staff assists with all stages of the clinical research process, including our team of principal investigators, project managers, study coordinators, research assistants, and administrative support.

We are positioned to continue our growth to serve more investigators who lead research aligned with rigorous best practices and findings that translate to improved public health; especially for studies focused on our diverse patient population. However, we cannot continue this growth without new financial resources, and have approached several potential donors to sustain the Berman Center’s tremendous success.

The Berman Center is located on the campus of Hennepin Healthcare, on the 4 th floor of the Parkside Professional Center on the eastern edge of downtown Minneapolis. The Parkside Professional Center is across the street from the Hennepin Healthcare Clinic & Specialty Center, and the convenient Parkside Parking Ramp occupies its lower floors.

The office space includes administrative and medical offices, fully equipped procedure/examination rooms, laboratory phlebotomy station, a reception area for central patient coordination, a secure medical records room, recruitment stations, patient education wing, support staff facilities, and a conference room. The laboratory is equipped for drawing, processing, storing and shipping specimens for multiple study protocols. All clinical and support staff have either private or shared offices that overlook Elliot Park green space.

Current Studies

Aging/Dementia

• ASPREE (ASPirin in Reducing Events in the Elderly). Aspirin trial and ASPREE-XT observational follow on study. Dr. Anne Murray, Co-PI. U.S. coordinating center for landmark NIA study with Monash University in Melbourne, Australia in over 19,000 healthy older participants for 13 years, with over $100 million in NIH funding, and over 200 publications regarding dementia, disability, frailty, genomics, and cancer outcomes.
• HATS (Healthy Aging in the Senior Years). Dr. Anne Murray, Co-PI, to explore reasons for the two-fold risk of dementia in older U.S. Blacks and to measure cardiovascular risk factors for dementia in 300 older Black community residents of the Twin Cities in collaboration with Mayo Clinic Co-PI Dr. David Knopman and community engagement partners Hue-MAN and the LinC.
• Sex-Specific Risk Factors and Trajectories of Blood Biomarkers for ADRD. Anne Murray.

Addiction Medicine : Dr. Gavin Bart, PI, leads the National Institute on Drug Abuse (NIDA) Center for Clinical Trials Network (CCTN) Northstar Node for multiple studies.

• ADAPT Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use Disorder
• EXHIT-ENTRE Exemplar Hospital Initiation Trial to Enhance Treatment Engagement
• COMPUTE 2.0 CTN-0095: Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings
• CTN-0095-A-1 : Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder
• CTN-0095-A-2: Reducing Stigma Toward People with Opioid Use Disorder Among Primary Care Clinicians
• CTN-0096: Culturally Centered MAT for OUD Implementation Facilitation for Primary Care and Addiction Treatment Programs Serving American Indian/Alaska Natives
• ED-INNOVATION CTN-0099: Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network
• CURB-2 CTN-0109: Randomized, Placebo-controlled Trial of Injectable Naltrexone and Monthly Injectable Buprenorphine for Cocaine Use Disorder
• CTN-0123: Facebook Intervention for Preventing Opioid Relapse among American Indian Women
• CTN-0127 : Engaging African American Faith-Based Leaders in a Substance Use Learning Collaborative
• MOUD CTN-0131: Office-Based Methadone versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder —A Pragmatic Hybrid Effectiveness/Implementation Trial
• HOPE Hemodialysis Opioid and Pain Reduction Effort. Dr. Kirsten Johansen.
• REACH Research and Evaluation Commercialization Hubs REACH DART. Kirsten Johansen.
• IDMS Intradialytic Myocardial Stunning

Infectious Disease

• STRIVE Strategies and Treatments for Respiratory Infections and Viral Emergencies. Dr. Jason Baker. COVID U.S./Mexico International Coordinating Center - network support. To investigate drugs and treatment strategies for adults in the hospital with respiratory or lung infection.
• OTAC Covid-19 outpatient observational study

Amyotrophic Lateral Sclerosis (ALS)

• PHOENIX – Phase III Trial of AMX0035
• CREATE/CAPTURE. DNA repository.

Historical Study Record :

Heart Disease - 10 NIH trials including:

• ALLHAT Antihypertensive and  Lipid-Lowering Treatment to Prevent Heart Attack
• SHEP Systolic Hypertension in the Elderly Program
• Multiple industry blood pressure trials
• FRESH (FIND) Healthy Food, Healthy Lives,
• ACCORD Action to Control Cardiovascular Risk in Diabetes
• ACCORDION ACCORD Follow-on Study
• ORIGIN Outcome Reduction with Initial Glargine Intervention
• DREAM Diabetes Related to Acute pancreatitis and its Mechanisms
• U300 Insulin Study

Dementia/Cognitive Impairment/Health Aging

• BRINK . BRain In Kidney Disease
• Minocycline . Antibiotic study
• Co-Enzyme Q-10. Antioxidant study
• IGF-I Myotrophin study
• TCH-346 study
• SPS3 Levels of Inflammatory Markers in the Treatment of Stroke

Alternative Medicine

• Chiropractic, Medication, and Self-Care for Neck Pain
• Manipulation, Exercise, and Self Care for Low Back Pain/Neck Pain
• PACBACK Housed staff and conducted participant study visits at The Berman Center
• Fractures and bone disease in living kidney donors
• WHI Women’s Health Initiative. Clinical site with over 5,000 participants

Moral Injury Prevention Program. Survey research and analysis

For more information about working with the Berman Center, please contact Brenda Kirpach at [email protected] or 612-873-6905. You can also visit our website at bermancenter.org