COMMENTS

  1. Jaundice

    Jaundice, also known as hyperbilirubinemia,[1] is a yellow discoloration of the body tissue resulting from the accumulation of an excess of bilirubin. Deposition of bilirubin happens only when there is an excess of bilirubin, a sign of increased production or impaired excretion. The normal serum levels of bilirubin are less than 1mg/dl; however, the clinical presentation of jaundice as scleral ...

  2. (PDF) Jaundice-review of clinical features, differential diagnosis and

    Jaundice can occur in babies, children, and adults. Jaundice is not an illness, but a medical condition in which too much bilirubin a compound produced by the breakdown of hemoglobin from red ...

  3. (PDF) Neonatal jaundice causes and management

    PDF | 80% of healthy neonates present with some degree of hyperbilirubinemia after birth, however, only 5-10% would require therapy to prevent damage or... | Find, read and cite all the research ...

  4. A Systematic Approach to Patients with Jaundice

    A stepwise approach to evaluation can be cost and time saving as well as a framework to improve patient outcomes. In this review, we will outline a diagnostic approach to jaundice, beginning with pathophysiology of cholestasis followed by hyperbilirubinemia and markers of synthetic dysfunction. Keywords: cholestasis; hyperbilirubinemia; jaundice.

  5. Jaundice revisited: recent advances in the diagnosis and treatment of

    Background Jaundice is a common symptom of inherited or acquired liver diseases or a manifestation of diseases involving red blood cell metabolism. Recent progress has elucidated the molecular mechanisms of bile metabolism, hepatocellular transport, bile ductular development, intestinal bile salt reabsorption, and the regulation of bile acids homeostasis. Main body The major genetic diseases ...

  6. (Pdf) a Systematic Review on Physiological Jaundice: Diagnosis and

    PDF | Jaundice is the most common physical abnormality in the first week of life. ... read and cite all the research you need on ResearchGate. Article ... This paper was written to give an insight ...

  7. The prevalence of neonatal jaundice and risk factors in healthy term

    Introduction. The term 'jaundice' is used to describe the yellow-orange discoloration of the skin and sclera because of excessive bilirubin in the skin and mucous membranes. 1,2 Jaundice itself is not a disease but rather a symptom or sign of a disease. Bilirubin is mainly formed when the haem component of red blood cells are broken down in the spleen to biliverdin and then unconjugated ...

  8. PDF Neonatal jaundice: aetiology, diagnosis and treatment

    Jaundice present as yellow discolouration of the skin and sclera in infants, indicating a raised serum bilirubin level leading to accumulation of bilirubin in the tissues, including the skin and mucous membranes. Jaundice is thought to be visible at bilirubin levels of around 90 mmol/litre in babies with pale skin tones.

  9. Neonatal Jaundice Management: Improving Clinical Knowledge of Jaundice

    first to observe early signs of jaundice, therefore, having improved knowledge, attitude, and good clinical practices toward neonatal jaundice is central to achieving favorable outcomes for the management of neonatal jaundice. We therefore write a commentary on a recently published paper "Neonatal Jaundice Management: Knowledge, Attitude,

  10. Jaundice

    Jaundice occurs due to an imbalance between bilirubin production and its clearance. Understanding the pathophysiology of jaundice is crucial to evaluate a patient with jaundice (Figure 1).Approximately 80% of bilirubin is produced from breakdown of senescent red blood cells (RBC) by reticuloendothelial (RE) cells in the spleen and liver when they reach the end of their life span of ...

  11. Assessment, management, and incidence of neonatal jaundice in ...

    Jaundice caused by hyperbilirubinaemia is a common phenomenon during the neonatal period. Population-based studies evaluating assessment, management, and incidence of jaundice and need for ...

  12. PDF Jaundice Clinical Manifestation and Pathophysiology: A Review Article

    Introduction. of in bilirubin Jaundice is when clinically there is an increase in the amount in the serum rising above 85mmol/l (5mg/dl). produce cord serum bilirubin unconjugated bilirubin of approximately is in 35mmol/L dl). After birth, jaundice is a reflection of the bilirubin present. to in to of Many variations in individual responses to ...

  13. PDF Obstructive Jaundice: Understanding the Pathophysiology

    The pathophysiology, clinical evaluation and investigations in a case of obstructive jaundice is discussed in this paper. KEYWORDS Jaundice, obstructive, causes, complications, investigations Introduction Obstructive jaundice is one of the most challenging types of jaun-dice. It can be treated successfully once the cause is ascertained.

  14. Jaundice revisited: recent advances in the diagnosis and treatment of

    Jaundice, a yellowish pigmentation of the skin and sclera, is caused by the disrupted excretion of bilirubin and biliverdin. Interestingly, some studies involving neonates or adults have shown that hyperbilirubinemia is protective against diseases, including metabolic syndrome and asthma, [ 2 , 3 ] suggesting that bilirubin may play a role as ...

  15. Knowledge Level and Determinants of Neonatal Jaundice: A Cross

    1. Background. Neonatal jaundice (NNJ) is a common condition worldwide occurring in up to 60% of term and 80% of preterm newborns in the first week of life [1, 2].Newborns show clinical signs which tend to start on the head and face and then spread down the trunk and limbs as a result of high serum levels of bilirubin.

  16. Neonatal Jaundice Management: Improving Clinical Knowledge of Jaundice

    Introduction. Neonatal jaundice is a common pediatric condition that refers to the yellowish coloration of the skin, sclera of the eye, and other organs of the body caused by the accumulation of bilirubin (American Academy of Pediatrics et al., 2004; Huang et al., 2022).It affects nearly 50% to 60% of full-term babies and 80% of premature babies develop jaundice within the first week ...

  17. PDF Unani Concept of Jaundice and its Management

    Jaundice is a yellowish discoloration of the skin, mucous membranes and sclera caused by elevated levels of the chemical bilirubin in the blood. Hamdard Medicus81 Vol. 58, No. 3, 2015 (hyperbilirubinemia). The term jaundice is derived from the French word. jaune, which means yellow.

  18. (PDF) Neonatal Jaundice

    Neonatal jaundice or neonatal hyperbilirubinemia results from elevated total serum bilirubin (TSB) and clinically. manifests as yellowish discoloration of the skin, sclera, and mucous membrane. In ...

  19. Deep Learning Approach for Early Diagnosis of Jaundice

    1 Background. Jaundice, also known as hyperbilirubinemia, is a yellow discoloration of the body mainly detected in the sclera, skin, and mucus membranes due to increased bilirubin level in the serum. Bilirubin is a byproduct of expired red blood cells breakdown, which metabolizes further in the liver for excretion from the body.

  20. PDF Jaundice Clinical Manifestation and Pathophysiology: A Review Article

    Introduction. Jaundice is when clinically there is an increase in the amount of bilirubin in the serum rising above 85mmol/l (5mg/dl). When in utero, unconjugated bilirubin is cleared in the placenta to pro-duce cord serum bilirubin of approximately 35mmol/L (2mg/ dl). After birth, jaundice is a reflection of the bilirubin present in the liver ...

  21. (PDF) Obstructive Jaundice: Understanding the pathophysiology

    The pathophysiology, clinical evaluation and investigations in a case of obstructive jaundice is discussed in this paper. KEYWORDS Jaundice, obstructive, causes, complications, investigations Introduction Obstructive jaundice is one of the most challenging types of jaundice. It can be treated successfully once the cause is ascertained.

  22. How to Write a Table of Contents for Research Paper: A Complete Guide

    Since you are always required to cover many different aspects in your study, navigating the document quickly becomes top priority. This is why all expansive academic papers require a table of contents (also known as TOC). This fragment of your paper is an overview of every topic explored in it.

  23. (PDF) Obstructive Jaundice: Understanding the pathophysiology

    Understanding the pathophysiology of obstructive jaundice is. essential for proper evaluation in order to prevent a delay in. the diagnosis: a careful history and physical examination help. in ...

  24. Jaundice

    Jaundice is the yellow color of skin and mucous membranes due to accumulation of bile pigments in blood and their deposition in body tissues. Jaundice should be distinguished from cholestasis, which refers to a decreased rate of bile flow. Depending on the clinical situation, jaundice and cholestasis may coexist or each may exist without the other. Although many sources confidently say that ...

  25. Defining mental health literacy: a systematic literature review and

    Purpose This paper aims to explore how the term "mental health literacy" (MHL) is defined and understand the implications for public mental health and educational interventions. Design/methodology/approach An extensive search was conducted by searching PubMed, ERIC, PsycINFO, Scopus and Web of Science. Keywords such as "mental health literacy" and "definition" were used.