Protein Data Bank: From Two Epidemics to the Global Pandemic to mRNA Vaccines and Paxlovid
COMMENTS
A quantitative and qualitative analysis of the COVID-19 pandemic model
Although, there is a variety of modeling approaches that have been proposed so far for prediction and evaluation of the COVID-19 disease, there are more questions that can still be answered. There are some related works that sensitivity analysis used in their studies [13,17]. They used this technique only for special variables and parameters.
11 Questions to Ask About COVID-19 Research
When hundreds of millions of people are vaccinated, millions of them will be afflicted anyway, in the course of life, by conditions like strokes, anaphylaxis, and Bell's palsy. "We have to have faith that people collecting the data will let us know if we are seeing those things above the baseline rate.". 3.
PDF COVID-19 Key Research Questions and Recommendations
COVID-19 CLINICAL TRIAL RECOMMENDATIONS. -As multiple federal research agencies have demonstrated, it is most ethical and prudent to enroll patients with COVID-19 in clinical trials rather than use clinically unproven therapies. There are multiple ongoing trials, some with adaptive designs, which potentially can quickly answer pressing ...
Coronavirus disease (COVID-19) pandemic: an overview of systematic
The spread of the "Severe Acute Respiratory Coronavirus 2" (SARS-CoV-2), the causal agent of COVID-19, was characterized as a pandemic by the World Health Organization (WHO) in March 2020 and has triggered an international public health emergency [].The numbers of confirmed cases and deaths due to COVID-19 are rapidly escalating, counting in millions [], causing massive economic strain ...
SARS-CoV-2 and COVID-19: The most important research questions
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.
The effect of the definition of 'pandemic' on quantitative ...
Travel rates. One important question about pandemic risk is what effect inter-regional travel rates have on the probability of a pandemic occurring 16,17,46,47.Here we model epidemics occurring in ...
Methodological quality of COVID-19 clinical research
We performed a systematic review to evaluate the methodological quality of currently available COVID-19 studies compared to historical controls. A total of 9895 titles and abstracts were screened ...
COVID-19 impact on research, lessons learned from COVID-19 research
The impact on research in progress prior to COVID-19 was rapid, dramatic, and no doubt will be long term. The pandemic curtailed most academic, industry, and government basic science and clinical ...
A quantitative and qualitative analysis of the COVID-19 ...
This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of ...
Knowledge, attitudes, and practices (KAP) toward COVID-19: a cross
Study participants and survey. We adopted a cross-sectional survey design to evaluate the public's knowledge, attitudes, and practices during the COVID-19 epidemic using an anonymous online questionnaire (see Additional file 1 for details). The survey was conducted via an online platform from a research company called Korea Research.
Falling living standards during the COVID-19 crisis: Quantitative
Despite numerous journalistic accounts, systematic quantitative evidence on economic conditions during the ongoing COVID-19 pandemic remains scarce for most low- and middle-income countries, partly due to limitations of official economic statistics in environments with large informal sectors and subsistence agriculture.
Key ethical questions for research during the COVID-19 pandemic
In these times of rapid change, with high levels of uncertainty, anxiety, social isolation, and financial pressure, mental health worldwide is likely to be at risk. Researchers are rightly ensuring that mental health research is included in the response to the coronavirus disease 2019 (COVID-19) pandemic.1 Here, we reflect on ethical issues to consider when conducting research on self-harm ...
Questions about COVID-19 and your research?
As the ongoing Coronavirus Disease 2019 (COVID-19) outbreak continues to change rapidly, here is information that the Harvard University research community may find helpful. We realize that the COVID-19 outbreak may cause hardship to research, however it is also important to weigh the possible harms to subjects, taking all issues into account.
Impact of the COVID-19 pandemic on mental health and well-being of
Introduction The COVID-19 pandemic has certainly resulted in an increased level of anxiety and fear in communities in terms of disease management and infection spread. Due to fear and social stigma linked with COVID-19, many individuals in the community hide their disease and do not access healthcare facilities in a timely manner. In addition, with the widespread use of social media, rumours ...
8 Major Findings and Research Questions
Major Findings and Research Questions INTRODUCTION. The COVID-19 pandemic, which began in late 2019, created unprecedented global disruption and infused a significant level of uncertainty into the lives of individuals, both personally and professionally, around the world throughout 2020. The significant effect on vulnerable populations, such as ...
Learning about COVID-19: a qualitative interview study of Australians
Quantitative surveys to determine how publics were responding to coverage of the COVID-19 crisis in news and social media have identified an association between COVID-19-related news and social media consumption and heightened anxiety and distress in Russia , China [29, 30] and USA . Malaysian research found that respondents mainly used ...
Questions About COVID-19 and Your Research
Research study personnel should let participants decide if they would like to wear a mask if the study procedures allow it. Researchers may wish to inform their study population of the current COVID-19 status on campus, or in the study location if elsewhere, including level of community transmission of COVID-19 and COVID-19 vaccination coverage ...
Summary of WHO infection prevention and control guideline for covid-19
The World Health Organization (WHO) published the seventh version of the infection prevention and control guideline for coronavirus disease 2019 (covid-19) in December 2023. The revision and development process undertaken for this guideline consolidates and updates technical guidance developed and published at the height of the covid-19 pandemic (2020-21) into a single guideline, following WHO ...
Effects of the COVID-19 pandemic on individuals with Chemical
Abstract Background: The Center for Disease Control has estimated that over 24 million have been infected with Covid-19 in the US with over 6,700,000 being hospitalized, and over 1,174,000 deaths. Several other industrialized countries show similar numbers (CSSE, 2021). Chemical Intolerance (CI) is characterized by multi-system symptoms initiated by a one-time high dose or persistent low-dose ...
Full article: Royal Society report: what would a comprehensive
Is the report relevant for policymaking? The Royal Society recently published a report entitled 'COVID-19: examining the effectiveness of non-pharmaceutical interventions' whose objective was to 'assess what has been learnt about the effectiveness of the application of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic of 2020-2023 by assembling and examining evidence ...
US government suspends funding for virus research group at center of
Before Covid-19 emerged, a US government grant to EcoHealth had funded studies into bat coronaviruses at the lab in Wuhan, China. Although US-funded research at the lab has not been linked to the ...
Covid origins in spotlight, as feds cut funding to virus hunters
Covid origins in spotlight, as feds cut funding to virus hunters. By Dan Diamond. with research by McKenzie Beard. May 16, 2024 at 8:04 a.m. EDT. The Washington Post's essential guide to health ...
IMAGES
VIDEO
COMMENTS
Although, there is a variety of modeling approaches that have been proposed so far for prediction and evaluation of the COVID-19 disease, there are more questions that can still be answered. There are some related works that sensitivity analysis used in their studies [13,17]. They used this technique only for special variables and parameters.
When hundreds of millions of people are vaccinated, millions of them will be afflicted anyway, in the course of life, by conditions like strokes, anaphylaxis, and Bell's palsy. "We have to have faith that people collecting the data will let us know if we are seeing those things above the baseline rate.". 3.
COVID-19 CLINICAL TRIAL RECOMMENDATIONS. -As multiple federal research agencies have demonstrated, it is most ethical and prudent to enroll patients with COVID-19 in clinical trials rather than use clinically unproven therapies. There are multiple ongoing trials, some with adaptive designs, which potentially can quickly answer pressing ...
The spread of the "Severe Acute Respiratory Coronavirus 2" (SARS-CoV-2), the causal agent of COVID-19, was characterized as a pandemic by the World Health Organization (WHO) in March 2020 and has triggered an international public health emergency [].The numbers of confirmed cases and deaths due to COVID-19 are rapidly escalating, counting in millions [], causing massive economic strain ...
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.
Travel rates. One important question about pandemic risk is what effect inter-regional travel rates have on the probability of a pandemic occurring 16,17,46,47.Here we model epidemics occurring in ...
We performed a systematic review to evaluate the methodological quality of currently available COVID-19 studies compared to historical controls. A total of 9895 titles and abstracts were screened ...
The impact on research in progress prior to COVID-19 was rapid, dramatic, and no doubt will be long term. The pandemic curtailed most academic, industry, and government basic science and clinical ...
This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of ...
Study participants and survey. We adopted a cross-sectional survey design to evaluate the public's knowledge, attitudes, and practices during the COVID-19 epidemic using an anonymous online questionnaire (see Additional file 1 for details). The survey was conducted via an online platform from a research company called Korea Research.
Despite numerous journalistic accounts, systematic quantitative evidence on economic conditions during the ongoing COVID-19 pandemic remains scarce for most low- and middle-income countries, partly due to limitations of official economic statistics in environments with large informal sectors and subsistence agriculture.
In these times of rapid change, with high levels of uncertainty, anxiety, social isolation, and financial pressure, mental health worldwide is likely to be at risk. Researchers are rightly ensuring that mental health research is included in the response to the coronavirus disease 2019 (COVID-19) pandemic.1 Here, we reflect on ethical issues to consider when conducting research on self-harm ...
As the ongoing Coronavirus Disease 2019 (COVID-19) outbreak continues to change rapidly, here is information that the Harvard University research community may find helpful. We realize that the COVID-19 outbreak may cause hardship to research, however it is also important to weigh the possible harms to subjects, taking all issues into account.
Introduction The COVID-19 pandemic has certainly resulted in an increased level of anxiety and fear in communities in terms of disease management and infection spread. Due to fear and social stigma linked with COVID-19, many individuals in the community hide their disease and do not access healthcare facilities in a timely manner. In addition, with the widespread use of social media, rumours ...
Major Findings and Research Questions INTRODUCTION. The COVID-19 pandemic, which began in late 2019, created unprecedented global disruption and infused a significant level of uncertainty into the lives of individuals, both personally and professionally, around the world throughout 2020. The significant effect on vulnerable populations, such as ...
Quantitative surveys to determine how publics were responding to coverage of the COVID-19 crisis in news and social media have identified an association between COVID-19-related news and social media consumption and heightened anxiety and distress in Russia , China [29, 30] and USA . Malaysian research found that respondents mainly used ...
Research study personnel should let participants decide if they would like to wear a mask if the study procedures allow it. Researchers may wish to inform their study population of the current COVID-19 status on campus, or in the study location if elsewhere, including level of community transmission of COVID-19 and COVID-19 vaccination coverage ...
The World Health Organization (WHO) published the seventh version of the infection prevention and control guideline for coronavirus disease 2019 (covid-19) in December 2023. The revision and development process undertaken for this guideline consolidates and updates technical guidance developed and published at the height of the covid-19 pandemic (2020-21) into a single guideline, following WHO ...
Abstract Background: The Center for Disease Control has estimated that over 24 million have been infected with Covid-19 in the US with over 6,700,000 being hospitalized, and over 1,174,000 deaths. Several other industrialized countries show similar numbers (CSSE, 2021). Chemical Intolerance (CI) is characterized by multi-system symptoms initiated by a one-time high dose or persistent low-dose ...
Is the report relevant for policymaking? The Royal Society recently published a report entitled 'COVID-19: examining the effectiveness of non-pharmaceutical interventions' whose objective was to 'assess what has been learnt about the effectiveness of the application of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic of 2020-2023 by assembling and examining evidence ...
Before Covid-19 emerged, a US government grant to EcoHealth had funded studies into bat coronaviruses at the lab in Wuhan, China. Although US-funded research at the lab has not been linked to the ...
Covid origins in spotlight, as feds cut funding to virus hunters. By Dan Diamond. with research by McKenzie Beard. May 16, 2024 at 8:04 a.m. EDT. The Washington Post's essential guide to health ...