phd biomaterials germany

PhD position: Biomaterials and Biofabrication

Job Offer from January 17, 2024

Join our dynamic and innovative research team as a PhD student where you will be at the forefront of cutting-edge developments in biomaterials, cell-material interactions and biofabrication techniques.

About the project

Within this research project, the successful candidate will have a unique opportunity to contribute to the future of tissue and food tissue engineering through the creation of advanced scaffolds incorporating living and engineered cells. You will be part of the Physical Chemistry of Polymers group at MPI-P, headed by Prof. Dr. Katharina Landfester .

Key responsibilities

• Develop novel biomaterials with a focus on their application in tissue engineering.
• Investigate and understand cell-material interactions to optimise scaffold performance.
• Apply biofabrication techniques to produce scaffolds incorporating living and engineered cells.
• Undertake material characterisation studies to ensure the quality and suitability of developed biomaterials.
• Undertake biocompatibility studies to assess the safety and efficacy of engineered scaffolds.
• Use confocal microscopy and other advanced imaging techniques to analyse cell behaviour within scaffolds.

Job requirements

We are looking for enthusiastic candidates with a Master's degree in polymer chemistry, materials science or a related field. The ideal candidate will have knowledge or experience in biomaterial development and characterisation, cell studies and confocal microscopy. A willingness to actively contribute to team efforts, coupled with a friendly and positive personality that fosters a supportive and inclusive working environment is highly valued. Fluency in English, both written and spoken, is required as English is the working language at the Max Planck Institute for Polymer Research.

The Max Planck Society is committed to employing more individuals with disabilities, and especially encourages them to apply. The Society seeks to increase the number of women in areas where they are underrepresented, and therefore explicitly encourages women to apply.

The position is available now. Remuneration will be according to the collective wage agreement for the public service 65% TVöD Bund EG13-1.

Your application

Applications should be sent by e-mail to: jobapplication-landfestergroup@... and cc to Dr. Maria Villiou , should indicate in the subject line “Application: Biomaterials and Biofabrication”, and must include the following:

• A letter of motivation (max. 1 page), clearly stating the specific interest of the candidate to join the group and work on this project, his/her career goals, etc.
• Curriculum vitae.
• Contact details of two referees.

Advanced Search ››

Dresden International Graduate School for Biomedicine and Bioengineering

Phd application.

call is closed

You Are the Future of Science

… a talented, motivated, and creative young scientist, with the spirit to envision the future direction research will take. We offer you exciting projects, innovative tools and a vibrant research environment to make that future possible.

Biomedicine

Cell, molecular and developmental biology, bioengineering and biomaterials, regenerative and degenerative biology, biochemistry, computational biology, digs-bb fellow awards 2024.

23 April 2024

Awards given to four DIGS-BB PhD students

DIGS-BB Fellow Awards 2023

20 April 2023

A remarkable number of seven awards – more than ever before – were given out this year

© Diez Group

Start of the first DIGS-BB Topical Partner Cluster (TPC)

9 February 2023

Kickoff Meeting in March for the first TPC with research groups from the Czech Academy of Sciences on “Cytoskeletal Dynamics Across Scales”

© MPI-CBG, Katrin Boes

Support for Cutting-Edge Research in Biology and Medicine: Alf Honigmann Receives 1.25 Million Dollars as New Allen Distinguished Investigator

16 December 2022

The Paul G. Allen Frontiers Group, a division of the Allen Institute, today announced eight awards of $1.25 million each to fund research projects led…

Thesis Defense

Alisa Hnatiuk: Aberrant expression of the MHC class II invariant chain cd74 induces autonomous beta-cell death in a novel zebrafish model of T1D

TU Dresden, Faculty of Biology | Room E33

Esteban Quezada: Post-transcriptional regulation of insulin mRNA mediated by G3BP1/2 condensates in beta cell biology

CRTD | Auditorium right

See you soon in Dresden

A career in science is among the most exciting and rewarding experiences. Pursuing a PhD is a challenging task that requires commitment, passion and hard work. Guided and trained by experts you will develop the skills needed to become an independent, creative and innovative scientist able to develop your own project ideas.

The Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) offers you an extraordinary opportunity to explore your capabilities, to brainstorm your ideas, to develop professionally and personally and to shape yourself as an outstanding scientist. Our mission is to help you become a visionary research leader. To accomplish this goal, we offer a structured training program with exciting interdisciplinary projects and outstanding expert supervision. In addition, built on a strategy of excellence, our PhD program has an open door policy and offers direct access to campus-wide facilities. Our world-class faculty will help you build a network that extends also to our alumni worldwide and will accompany you throughout your life.

I would like to invite you to explore our website and discover the possibilities that our Graduate School offers for your future career. Dig into our research interests; take a look at our faculty and what drives their research; find out about our current PhD students from around the world; and explore the truly interdisciplinary projects, the internship possibilities and the career development opportunities.

The Graduate School team looks forward to hearing from you and to learning about your ideas and research interest. See you soon in Dresden!

Prof. Dr. Gerhard Rödel. Spokesperson DIGS-BB

Biomaterials

Research Program

Research Groups

Micromechanics of Biological Materials

Biofilm-based Materials

Adaptive Fibrous Materials

Mucus-based Materials

Development of Mineralized Skeletal Materials

Hierarchical Structure of Biological and Bio-inspired Materials

Mechanobiology

Matters of Activity

Stochastic Processes in Complex and Biological Systems

Former Research Groups

Doctorate procedure (PhD)

Attention the communication with the doctoral office must be performed electronically.

The communication with the doctoral office must be performed electronically using following link:

  https://webapps.itmc.tu-dortmund.de/webapps/prod/dev/promotion/#/home

Meeting Dates of the Doctoral Commission

All requests need to be submitted at least four business days prior the meeting of the doctoral commission in order to be considered. Usually the meetings are on Mondays, that means submission of the documents until Wednesday before the meeting.

2024                  Start: 15:00 hrs

Application as Doctoral Student (PhD)

The application to the doctoral program at the Faculty of Biochemical and Chemical Engineering has to be performed at the individual research groups .

Please send your application data to the head of the research group, who will serve as scientific supervisor during the doctoral procedure.

When having a commitment from the supervisor you are obligated to apply for admission from the faculty using following link:

Admission as Doctoral Student

Those aspiring doctoral candidate status need to submit an application including following documents:

• transcript of records bachelor of science (Zeugnis mit Gesamtkredits)
• final grade certificate bachelor of science (Urkunde)
• transcript of records master of science (Zeugnis mit Gesamtkredits)
• final grade certificate master of science (Urkunde)
• curriculum vitae

All documents have to be submitted at least four business days prior to the meeting of the doctoral commission in order to be considered. Since originals of the aforementioned records and certificates need to be presented as well, a personal contact is required.  An appointment is obligatory. Please use: promotionsausschuss.bci tu-dortmund de .

In accordance to the “Landeshochschulgesetz HG NRW 2014 §67(5)” and the “Promotionsordnung 2014 §5(1)” students working on their doctoral thesis are obligated to join the doctoral program by an enrollment with the faculty.

The doctoral candidate status is restricted to four years but it can be extended on request. The application for extention for the first two years has to be submitted using the following link . Afterwards the applications for extension have to be submitted by mail using the following ( form ).

Extension of the PhD status

The doctoral candidate status is restricted to four years and it can be extended twice up to six years using following link .

There might be an opportunity to extend this period further based on certain live situations (e.g. pregnancy). These requests have to be submitted by mail using the following ( form ).

Submission of the Doctoral Thesis

The contents of the doctoral thesis must be distributed within the scientific community in order to finish the doctoral program successfully (Promotionsordnung 2014, §18(3)). Please be aware that this might cause copyright issues with previous publications, such as journal articles. It’s therefore advised to check your own copyright situation prior to writing your thesis! A monographic doctoral thesis requires a final distribution by a commercial publisher (e.g. Shaker, Dr. Hut and Cuvillier) or an online publication by the University (Eldorado). A cumulative doctoral thesis does not require such a distribution, since the information is already available in the journal articles. The introduction and text body (Manteltext) of a cumulative thesis should therefore be limited to information mentioned in the publications (PromO 2014, §18(3) “…Veröffentlichung in ungekürzter Form…”). In this respect it is not recommended to include unaccepted journal articles in the thesis, due to the risk of subsequent changes.

Required documents

Upon finishing the thesis the doctoral candidate has to upload several documents. In order to be considered by the doctoral commission the documents have to be submitted at least four business days prior to the meeting. The printed version of the thesis can be sent as parcel or be handed in at the doctoral office. In this case an appointment is obligatory ( promotionsausschuss.bci tu-dortmund de ).

Template of the forms and the necessary information can be found in the electronic system when you look in the upload procedure.

• paper copies (6) of the doctoral thesis (references in ACS format,  template title page )
• PDF-file "submission declaration form" *
• PDF-file "proof of participation" in  structured doctoral program  signed by supervisor *
• PDF-file "summary in German" signed by supervisor (less than 300 words) *
• PDF-file "summary in English" signed by supervisor (less than 300 words) *
• PDF-file "separate title page"
• PDF-file "form regarding co-author contributions" signed by supervisor *
• PDF-file "list of own publications" signed by supervisor *
• PDF-file "up-to-date curriculum vitae" signed by the student *
• PDF-file "plagiarism check" signed by student and supervisor (first 5 pages) and upload! In case of unclear citations please upload the whole report with active links.
• PDF-file "doctoral thesis"

*unsigned versions of the marked pdf-documents have to be attached in the appendix of each printed thesis as well as in the electronic version of the thesis

Oral Examination

After complete submission of the documents to the doctoral office the doctoral commission reviews all documents and appoints an examination board. The doctoral commission is not obligated to follow the suggestions of the candidate. The doctoral commission requests the supervisor to schedule the oral examination with the candidate as well as the members of the examination board. Afterwards all participants of the examination are invited by the doctoral office and the reports are requested from the referees. The student has the opportunity to read the reviewer reports three to five business days prior to the examination in the doctoral office. Copies, records and personal notes are not allowed and an appointment is obligatory ( promotionsausschuss.bci tu-dortmund de ).

The head of the examination board informs the student about the grades right after the examination, a confirmation letter is sent from the doctoral office to the student afterwards.  

Due to the Corona situation the following procedure has been defined by the faculty of BCI for oral doctoral examinations:  

• Contrary to the “Promotionsordnung” it is possible to take the exam during the corona crisis in presence of the members of the examination board only.
• An appointed external member of the examination board (“externer Gutachter”) is obligated to participate in the examination. A conferencing service like (Zoom, Webex etc.) might be used to comply with this rule.
• The doctoral examination has to be open to the members of the faculty. This can be achieved by conferencing service as well. In order to control the access a registration in advance is recommended.
• The technical aspects related to the conferencing service are organized by the doctoral student. One further person joining the examination physically is advised.
• If there are technical issues and the external member of the examination board or the members of the faculty cannot join the procedure the examination will be canceled.
• The doctoral student has to apply (scanned letter with signature) for this kind of examination by the doctoral commission ([email protected]).

If you agree to this procedure, you have to send an informal letter, indicating that you wish to do your exam in accordance with these regulations when submitting your thesis!

Finalization

The student is obligated to implement the examination board's comments in the final version of the thesis within one year (date of oral examination). Furthermore the  title page  has to be changed and the administrative appendix (section "Submission of the Doctoral Thesis" items marked with *) has to be removed from the thesis.

There are multiple different modes for publication of the final thesis in the “Promotionsordnung §18(3)”, three of which are common:

• Monographic dissertations are usually published by an official publisher (e.g. Shaker, Dr. Hut and Cuvillier ). A confirmation letter of the publisher is required containing author, title, ISBN number and information about minimal circulation. 10 paper copies need to be provided to the doctoral office.  
• Another strategy to publish a monographic dissertation is the electronic publication by the library of the university . Therefore a PDF-File (type A) and 10 paper copies are required to be provided to the doctoral office. An additional  form  is needed.  
• For cumulative dissertations 10 paper copies are required containing the text body as well as the publications and have to be handed in at the doctoral office.  

For finalization, the required amount of 10 copies of the thesis as well as the below-mentioned documents have to be submitted at the doctoral office. The printed version of the thesis can be sent as parcel or be handed in at the doctoral office. In this case an appointment is obligatory ( promotionsausschuss.bci tu-dortmund de ).

Additionally the following document have to be uploaded using the following link .

• PDF-file "final title page"

The final version of the printed thesis is transferred to the members of the examination board by the doctoral office for cross checking.

After the approval of the members of your examination board you receive a mail asking for a finalization of your documents. You have to upload

• PDF-file "form for certificate data" signed by student and supervisor ( form )
• PDF-file "actual curriculum vitae" signed by student

 This is your last task before the certificate can be issued.

Afterwards the approval of the examination board 4 copies of the dissertation are submitted to the library by the doctoral office (not by the doctoral student). The library sends a confirmation to the doctoral office. The date of the library confirmation letter has to be filled-in in above-mentioned form by the doctoral office. Please leave it blank.

Now the certificate can be issued by the dean's office.

It usually takes three months and the certificate will be sent by registered mail from the dean’s office.

• Promotionsordnung 2022 (German) PDF (136 KB)

For older doctoral regulations, please contact the doctoral office.

PhD position in Biomaterials

Job Information

Offer description.

Within the Biomaterials and Tissue Engineering research group of the KU Leuven Department of Materials Engineering, we perform research on the design and production of biocompatible materials for biomedical applications. We apply an interdisciplinary approach encompassing knowledge from materials science, chemistry, biology and medicine to understand the relationship between the microstructure, surface properties, functional properties and biological behavior of implantable biomaterials. This knowledge will allow us to develop more durable biomedical devices with an improved therapeutic effect. In the framework of an intrauniversity collaboration with the KU Leuven Department of Oral Health Sciences, we are currently developing the next generation of ceramic dental implants.

Website unit

Functionally graded materials (FGMs) are materials of which thecomposition, microstructure or porosity gradually varies throughout thecomponent. This allows tailoring (combinations of) macroscopic properties tomeet specific non-homogeneous service requirements that conventionalhomogeneous materials cannot accomplish. Additive manufacturing (AM) enablesproducing patient-specific implants with a customized geometry while optimizingenergy and raw materials consumption. Moreover, AM offers the advantage ofrealizing 3D FGMs with a gradient in the axial as well as radial direction,which cannot be achieved by conventional processing. While AM of metals andpolymers is relatively well-established, ceramic-AM has mainly been focused onproducing porous structures, such as scaffolds. Within this project, we willestablish the basic knowhow to realize ceramic materials incorporating afunctional gradient by means of AM. Focus will be on zirconia-based dental materialsfeaturing a smooth porosity gradient from fully dense core to a porous outersurface. The introduction of surface porosity entails a risk of reducing themechanical properties, and maybe more importantly increases the ageingsensitivity, requiring the mechanical strength and ageing-resistance of theceramics to be monitored and possibly improved. Conventionally processed ceramicswill serve as a bench mark.

Requirements

• You combine a Master's degree in Materials Engineering, Chemical Engineering or Biomedical Engineering or a related discipline, with a solid background in ceramic materials and/or additive manufacturing. A Master's degree with a final 'cum laude' grade is required to enter the KU Leuven Arenberg Doctoral School.
• You have a profound interest in bridging the gap between engineering and biomedical sciences, hence are willing to broaden your field of expertise in related assessment techniques, such as biomechanical testing. 
• You combine a strong interest in experimental work (colloidal processing, microstructural characterization,  mechanical testing) with expertise in materials modeling.
• You like to work in an interdisciplinary team of international researchers and show willingness to learn/explore innovative technologies and techniques.
• You have a creative mind-set, take initiative, and are not afraid to address innovative ideas and new opportunities.
• You are fluent in English, both written and spoken.

Additional Information

• A research position in a young and dynamic interdisciplinary working environment with the opportunity to pursue a PhD in Materials Engineering, typically a 4 year trajectory.
• An attractive salary package, complemented with multiple benefits (health insurance, access to university infrastructure and sports facilities, etc.).
• Ample occasions to develop your scientific and personal skills. Besides opportunities offered by the research group, further doctoral training for PhD candidates is provided in the framework of the KU Leuven Arenberg Doctoral School ( https://set.kuleuven.be/phd ), known for its strong focus on both future scientists and scientifically trained professionals, who will valorize their doctoral expertise and competences in a non-academic context. More information on the training opportunities via https://set.kuleuven.be/phd/dopl/whytraining.&nbsp ;
• A stay in a vibrant environment in the hearth of Europe. The university is located in Leuven, a town of approximately 100000 inhabitants, located close to Brussels (25 km), and 20 minutes by train from Brussels International Airport. This strategic positioning and the strong presence of the university, international research centers, and industry, lead to a safe town with high quality of life, welcome to non-Dutch speaking people and with ample opportunities for social and sport activities. The mixture of cultures and research fields are some of the ingredients making the university of Leuven the most innovative university in Europe. Further information can be found on the website of the university: https://www.kuleuven.be/english/kuleuven/.&nbsp ;

Interested?

For more information please contact Prof. dr. Annabel Braem, tel.: +32 16 32 15 34, mail: [email protected] .

You can apply for this job no later than May 02, 2023 via the  online application tool

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at [email protected] .

Work Location(s)

Where to apply.

Spider silk & protein materials

Molecular Biology

Cell Culture

3D Printing

Meet Prof. Scheibel

Prof. Dr. Thomas Scheibel is full professor for Biomaterials and head of the department at the University of Bayreuth, Germany. He further is currently Vice President for Research at his University.

After studying biochemistry at the University of Regensburg, Germany, he graduated in 1994. He obtained his PhD (Dr. rer. nat.) in 1998 from the Institute of Biophysics and Physical Biochemistry at the University of Regensburg, Germany. After three years as a postdoc at the University of Chicago, Chicago USA, he was assistant professor (C1) at the Technical University of Munich, Germany, and finished his habilitation in 2007.

Amongst his awards are the “Junior Scientist Award of the Materials week” (2004), the “Communicator Award of the Promega GmbH” (2005), the “Innovation Award from the Bavarian Prime Minister” (2006), the Award “Innovation made by nature” of the German Federal ministry of science (2007), the “Heinz-Maier-Leibnitz Medal” (2007), the “Karl-Heinz-Beckurts-Award” (2008), the “Dr R A Mashelkar Endowment Lecture on Advanced Materials”, National Chemical Laboratory, India (2013) and the “Dechema-Award” (2013). Since 2014 he is a member of the German National Academy of Science and Engineering (acatech).

CV_Thomas Scheibel

What our researchers are saying

Bin Zainuddin, Muhammad Shakir (M.Sc.)

graduate student

I got to know the group multiple times during my master’s studies in Biofabrication and found their research very interesting. I have a process engineering background and the group is diverse enough to also accommodate research in engineering topics not directly related to biomaterials. The atmosphere here is also open, I can freely discuss with my fellow PhD candidates as well as senior staff about anything.

Ng, Xuen (M.Sc.)

My scientific development began with the study program Biochemistry & Molecular Biology at the UBT, and it soon became clear to me that it is particularly the biology on a molecular level which fascinates me the most. Since then I gradually elaborated more into this particular direction and finally arrived in the multidisciplinary field of biomaterials. That gave me the opportunity to get first hand experience in the exciting field of tissue engineering during my Master Thesis, which path I will continue during my PhD studies. The collaboration with colleagues from a multitude of disciplinary backgrounds is remarkable and allows the view on the scientific challenges of our time from different angles to overcome them together.

Dr. Salehi-Müller, Sahar

group leader

As a young researcher, joining the chair of Biomaterials gave me the opportunity to establish my research group focusing on biofabrication and engineering of various tissues like cornea, neuronal and musculoskeletal tissues. I enjoy the possibility of broad national and international networking and collaboration at the UBT.

Dr. Gruhn, Thomas

At the Chair of Biomaterials I am engaged in computer simulations. This is a good complement to experimental investigations. It is the exchange between the colleagues, who bring a wide range of knowledge with them that leads to a good and creative working atmosphere.

Our research groups...

Privacy Overview

• General Information
• Tuition fees

Application & Admission

Language requirements, program features.

• List of Universities

2716 Study programs

Study Biomaterials in Germany: 10 Universities with 15 English Degree Programs

All important info for international students in germany (2024/2025).

Biomaterials, an innovative field at the intersection of medicine and biotechnology, focuses on developing and applying natural or synthetic materials to interface with biological systems. These materials are integral to transforming healthcare by treating, repairing, or replacing damaged tissues and organs. With diverse applications, such as drug delivery, tissue engineering, and medical implants like artificial joints and dental prosthetics, biomaterials are gaining prominence in modern medicine. Students studying biomaterials acquire essential knowledge and skills to design, synthesize, and evaluate materials that interact safely and effectively with living organisms. As the healthcare industry demands more innovative solutions, professionals specializing in biomaterials are poised to contribute to cutting-edge research and development, ultimately shaping a healthier future for all.

Study Programs in English

Universities

Universities in International Rankings

€ 0 (13 programs for EU citizens/Non-EU)

€ 4,500 per semester (1 program for EU citizens/Non-EU)

Winter Semester

between May 31 and April 15

Summer Semester

between July 15 and September 01

Top-ranked German Universities in Biomaterials

public University

No. of Students: approx. 27,000 students

Program Fees: € 0 (per semester)

Tuition Fees

3 english degree programs for biomaterials in germany.

TU Darmstadt Darmstadt

Functional advanced materials engineering with artificial intelligence for sustainability (fame ais).

Justus Liebig University Giessen Giessen

Sustainable chemistry.

Rhine-Waal University of Applied Sciences Kleve

Application Deadlines

Winter Semester 2024/2025

Summer Semester 2025

Winter Semester 2025/2026

Open Programs

12 programs

14 programs

Application Modes

Application process.

Rosenheim Technical University of Applied Sciences Rosenheim

International bachelor of wood technology.

TU Dortmund University Dortmund

Mechanics of sustainable materials and structures - ms² [triple degree 🇩🇪🇫🇷🇮🇹].

TU Bergakademie Freiberg Freiberg

Advanced materials analysis.

TOEFL Scores

Cambridge Levels

5.5 (2 programs )

72 (4 programs )

B2 First (FCE) (3 programs )

7 (1 program )

95 (1 program )

C1 Advanced (CAE) (4 programs )

Wood Technology

Biomaterials Science

Johannes Gutenberg University Mainz / TU Darmstadt Mainz / Darmstadt

Soft matter and materials.

3-8 semesters

→ View all programs with online courses

Master of Science

Bachelor of Engineering

Bachelor of Science

Winter intake

Summer intake

Winter & Summer intake

List of all German Universities offering English-taught Study Programs in Biomaterials

Friedrich Schiller University Jena

Program Fees: € 0

M.Sc. (Master of Science)

Johannes Gutenberg University Mainz

Justus Liebig University Giessen

Kiel University

Philipps-Universität Marburg

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Biomaterials

The Biomaterials facility provides scientific and technical expertise in microfluidic technology, in particular droplet-based microfluidics for synthetic biology and biomedical applications. Additionally, the facility provides state-of-the-art technologies for in-vitro engineering of human 3-D tissue models that can recapitulate healthy and disease tissue conditions. Our best expertise is in fabrication of scaffold-free skin models and in mimicking several skin ailments ranging from atopic dermatitis, psoriasis and skin wounds. Moreover, the facility provides support with high resolution analysis of biomaterials by means of cryogenic and room temperature scanning electron microscopy. The Biomaterials facility is operating in Stuttgart, and is headed by Dr. Ilia Platzman.

Microfluidics:

Microfluidics combines principles of science and technology, and enables the user to handle, process and manipulate fluids of very small volumes – down to less than a few picoliters – via microchannels. This technology permits the integration of multiple laboratory functions into one single microfabricated chip, requires minimal manual user intervention and sample consumption, and allows for fast data analysis and very high precision. For fundamental and applicable, biomedical, biophysical and synthetic biology research the Biomaterials facility provides the following scientific and technical expertise: design and development of various microfluidic functional units (e.g., droplets generator, observation, sorting and picoinjection); laser lithography; clean room operation; and analysis of the microfluidic devices’ performances.

Specifically, we are experts in the capacities of the microfluidic technology technology in the following topics: (1) Bottom-up assembly of bio-inspired synthetic cells (Figure 1) and (2) Mimicry of the cellular environment for personalized cell therapies (figure 2).

Fig 1. Schematic representation of a modular engineering approach for the sequential bottom-up assembly of cellular systems by means of an automated, high-throughput, droplet-based microfluidic technology.  

Fig. 2. Schematic representation of a modular droplet-based microfluidic device for application as a “hands-off” automated assay for the efficient selection of particular cells of interest. The encapsulation module shows the flow-focusing junction in which the cell-containing droplets are generated. The droplets flow into the incubation and observation module for high-throughput microscopy analysis of individual cells interactions. Following the analysis, the droplets are reinjected into the electric field-mediated sorting module, where an electric field is triggered based on the microscopic detection of a particular events. The selected droplets then flow into the release module, in which the cells will be released into physiological conditions for phenotype and functional analysis.  

Skin tissue models:

Worldwide, there is a consensus in the need to reduce and replace animal models. Therefore, tissue engineered in-vitro human 3-D models that can recapitulate healthy and disease native tissue are in high demand. Skin is the largest organ of the human body and the primary barrier against the external environment, protecting the internal organs from chemicals, radiation, and pathogens. There are several incurable skin diseases that manifests from environmental and genetic factors. The Biomaterials facility provides expertise in fabrication of scaffold-free skin models and mimicry of several skin ailments ranging from atopic dermatitis, psoriasis and skin wounds. Scaffold-free models are prepared by single cell extracellular matrix (ECM) coating and accumulation technique where human dermal fibroblasts are coated layer-by-layer with ECM moieties and assembled. The assembled cells rapidly form thick underlying dermal compartment. Human epidermal Keratinocytes are then added and the models are cultured in air-liquid interface, thereby mimicking the human skin architecture (Figure 3A). Such scaffold-free skin models can be cultured for long-term with minimal constriction and degradation, which allows testing of novel drugs for longer period of time. Furthermore, the bottom-up approach allows inclusion of other important cell types that reside in native skin. The facility has an expertise to include vascular and immune cells within the skin models (Figure 3B). The fabricated immno-competent and vascularized human skin models can be utilized to mimic several inflammatory skin diseases and as a reliable testing platform for clinically-relevant therapies.

Fig. 3. Scaffold-free in-vitro skin models A) H&E staining of cryo-sectioned full-thickness human skin model depicting differentiated epidermis with visible cornification B) Confocal image of blood vessels (red, CD31 stained) in the fabricated vascularized skin models (Blue, DAPI stain).  

• Genius Loci
• Lectures & Seminars

• THE BOTTOM-UP ROUTE TO NANO- AND BIOMATERIALS
• SPECIFIC FUNCTION BY MACROMOLECULAR DESIGN
• POLYMER SYSTEMS TO EMULATE LIVING MATTER
• BIOMATERIAL INNOVATION FOR MEDICINE AND TECHNOLOGY

Praktikumsangebot für Studenten

Upta quo occae sim etum is doluptium quodit debit, il moluptatem que velictur sin cum facerferion con pelescius dolorum quasit

The Max-Bergmann-Center of Biomaterials is part of the Technische Universität Dresden and the Leibniz-Institut für Polymerforschung Dresden e.v.

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• Published: 15 May 2024

How Iranian students can master integration into German academia

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Thousands of Iranians study at German universities every year, but many struggle with the German academic system. Here, we offer some advice.

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Department of Chemistry, University of Hamburg, Hamburg, Germany

Ata Makarem

Mannheim Business School, University of Mannheim, Mannheim, Germany

Molecular Structure Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

Karel Douglas Klika

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Makarem, A., Klika, K.D. How Iranian students can master integration into German academia. Nat. Phys. (2024). https://doi.org/10.1038/s41567-024-02490-4

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Published : 15 May 2024

DOI : https://doi.org/10.1038/s41567-024-02490-4

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