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Thank you for your interest in joining the SAMRC team.

Dedicated to improving the nation’s health and quality of life, the SAMRC relies on the knowledge, skills and professionalism of our staff.

Successful candidates have the opportunity to work with some of the world’s most innovative researchers and partner institutions to ultimately build a healthy nation for all.

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• Scientist B Careers – Medical Research Council (MRC UK) /UVRI and LSHTM Uganda Research Unit

Job Title:   Scientist B

Organisation:  Medical Research Council (MRC UK) /UVRI and LSHTM Uganda Research Unit

Duty Station:  Entebbe, Uganda

Reports to: Principal Investigator

Position Code: SB -424

The Medical Research Council (MRC UK) is an internationally recognised centre of excellence with dominant research themes in the areas of HIV and emerging infections, vaccines and immunity, and chronic diseases and cancer. Through a multidisciplinary approach, intersecting basic science, epidemiological research, social-behavioural research and the conduct of new intervention evaluation studies, the Unit contributes knowledge on changing epidemics and diseases, the evaluation of innovative health care options, treatment and prevention and the development of health policy and practice in Africa and worldwide. Following the signing of strategic transfer agreements between the London School of Hygiene & Tropical Medicine (LSHTM) and the Medical Research Council (MRC UK), the Unit formally joined LSHTM on 1st February 2018. The exciting new partnership will boost research capacity into current and emerging health issues in Africa and throughout the world. The Unit is based at the UVRI Entebbe campus with established outposts in Kalungu, Masaka, Wakiso and Kampala Districts.

Job Summary: The Scientist B will  lead a project focused on understanding how early-life infectious and nutritional exposures in tropical Africa affect cardiovascular disease risk. The role involves supervising and conducting a clinical research study, collecting and analyzing data on physical determinants of non-communicable diseases from a birth cohort, and coordinating between clinical and research teams to ensure smooth operation, timely sample collection and processing, accurate data generation, analysis, and adherence to ethical procedures. Ideal for an experienced medical doctor transitioning into clinical and research project management

Key Duties and Responsibilities:

Contributing to the design of research studies and taking an active role in;

• Writing study protocols & SOPs;
• Gaining approval from regulatory bodies;
• Developing detailed implementation plans & resourcing budgets;
• Recruiting and training study team members; and,
• Writing progress reports to regulatory and funding bodies.

Leading the implementation of the “EMaBS at 21” research study, through the following activities;

• Ensuring that plans, protocols and procedures are reliably followed;
• Ensuring that research is conducted according to best practice/high standards;
• Ensuring that all research volunteers are treated ethically with respect and compassion;
• Ensuring that data is entered accurately and reliably and data security routines are implemented;
• Assisting in obtaining continuing regulatory approvals for the study before expiry;
• Participating in data cleaning, analysis and project evaluation; feeding lessons learned back into the revision or design of new projects;
• Participating in the roll-out of the research findings and dissemination of results to stakeholders;
• Managing study resources (including finances, HR, equipment & facilities), ensuring efficient and ethical usage and complying with all Unit accountability requirements.
• Leading the study team, in a manner that empowers them to operate according to GCP and GCLP;
• Coordinating the activities of the study team, and providing feedback to and from the PI and Science meetings;
• Contributing to communication of study results through publications, poster presentations and scientific conferences; and,
• Providing mentorship to other members of the study team.
• Performing any other general I-Vac activities as may be assigned by Lab Manager, Project leader or Head of Programme.

Financial Management;

• Delegated financial (signing) authority for amount of up to Uganda Shs 500000 with expenditures above this limit being secondarily approved by the PI.

Line Management Responsibilities;

• The position holder is the first line supervisor of staff (e.g. clinicians, nurses,
• counsellors, field workers) for projects that he or she is responsible for and is also responsible for safeguarding safety and well-being of project research participants.

LSHTM Integration;

• Liaise, through the line manager, with LSHTM Communications and Engagement team.
• MBChB and Clinical training;
• MSc in Public Health, Research Methods, Epidemiology, Clinical Trials, or other relevant subject;
• GCP certification;
• Should possess minimum two years’ experience in working in clinical research environment;
• Experience in working in a medical research setting;
• Experience in leading teams;
• Experience in liaising between clinical and research teams;
• Experience working in research laboratory;
• Good clinical research conduct and practice;
• Ability to learn;
• Excellent analytical skills and Thoroughness;
• Personal integrity and Emotional resourcefulness;
• Proactivity and Concern for Excellence;
• Flexibility and Openness to others;
• Results Orientation and Service Orientation;
• Service Orientation; and,
• Development Orientation.

How to Apply

Follow the link below to fill a form and submit your application documentation:

Filling the form more than once will lead to automatic disqualification. High level of integrity while filling the form is required and will be considered during shortlisting.

All candidates should combine all their application documentation i.e. cover letter, CV & certified copies of academic documents into one PDF document. Only shortlisted candidates will be contacted for an interview. This position is open to Ugandan nationals only. Strictly follow the application procedure as failure to do so will lead to automatic disqualification. Only online applications through the link provided will be accepted. You will receive a notification in your email if your application and documentation have been successfully received.

N.B: You will be required to present certified copies of your academic documentation before employment.

The applications should be addressed to:

The Head of Human Resources,

MRC/ UVRI and LSHTM Uganda Research Unit,

P.O. Box, 49, Entebbe,

Consider your application unsuccessful if not contacted within eight (8) weeks after the closing date of the advert. Any form of lobbying at any stage will lead to automatic disqualification. By submitting your personal information, you consent to the MRC/ UVRI and LSHTM Uganda Research Unit holding and using it in accordance with its recruitment policy and procedure. The Unit reserves the right to verify documents attached with the relevant awarding institutions to authenticate their validity.

NB: MRC/UVRI & LSHTM Uganda Research Unit strives for inclusion and diversity and therefore considers all job applicants based on merit without regard to race, sex, color, national origin, religion, age, marital status, and disability. We highly encourage persons with disabilities to apply and compete for different job openings at the Unit. The Unit is an equal opportunity employer committed to having a diverse work force and does not ask for money at any stage of recruitment.

Deadline: 19 th April 2024 

For more of the latest jobs, please visit  https://www.theugandanjobline.com or find us on our facebook page  https://www.facebook.com/UgandanJobline

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Professor Richard Lathe

Honorary Fellow, Division of Infection and Pathway Medicine

Richard Lathe graduated BSc (Molecular Biology) from the University of Edinburgh, studying under Bill Hayes and Martin Pollock. This was followed by Docteur es Sciences under Rene Thomas at the University of Brussels (Ciba-Geigy Fellowship). His postdoctoral studies were with Ekkehard Bautz at Heidelberg (EMBO), and Michael Ashburner at Cambridge (SERC). He was subsequently appointed Deputy Scientific Director at Transgene, Strasbourg, France (Biotech industry) and then Head of Molecular Biology at ARC ABRO, Edinburgh. Returning to Strasbourg to work with Pierre Chambon he was for several years titular Professor and Director of the Biotechnology School at the University of Strasbourg. For more than 10 years he was Professor and Chairman of the Centre for Genome Research at the University of Edinburgh. Other employments have included Permanent Advisor, GLSV Munich, Germany (Venture Capital for science start-up), Director, Pieta Research Consultancy, Edinburgh, and Professor at the State University of Pushchino, Moscow, Russia. He is Honorary Fellow at the Division of Infection and Pathway Medicine at Edinburgh University.

Research Interests

Research experience has ranged from bacterial genetics to Drosophila to vaccines against viral disease. He was instrumental in the development of the vaccine that has now eradicated rabies in France and other European countries. Accomplishments include the generation of the first transgenic sheep. Highly-cited publications concern the design of oligonucleotide probes from amino acid sequence data, the development of the rabies vaccine, and gene cloning advances focusing on breast cancer and steroid metabolism.  Previous grant awards have been from the Wellcome Trust, Medical Research Council, the Ministry of Agriculture and Food, the Biotechnology and Biological Sciences Research Council, the Gatsby Charitable Foundation, and the European Commission, where he was Coordinator for a trans-Europe research initiative.

Recent research aims towards an understanding of brain function and dysfunction. Notable contributions include the discovery of CYP7B, a steroid and sterol hydroxylase predominantly expressed in the hippocampus. His monograph on autism was commended by the British Medical Association (2007).  Current research focuses on the potential contribution of infectious agents to Alzheimer disease and other conditions including autism, epilepsy, and schizophrenia. His current focus is on understanding the link between steroid/sterol metabolism, cognition, ageing, and brain disease.

Professor Lathe maintains an active interest in the origin of life, and is the originator of the Tidal Chain Reaction theory.  He has acted as Expert Witness at the European Patent Court and Expert Reviewer for the European Commission.

Research Theme

• Host-Pathogen Interaction

Selected Publications

1.  Lathe, R. (1985) Synthetic probes deduced from amino acid sequence data: theoretical and practical considerations. J. Mol. Biol. 183, 1–12

2.  Lathe, R., Kieny, M.P., Gerlinger, P., Clertant, P., Guizani, I., Cuzin, F. and Chambon, P. (1987) Tumor prevention and rejection with recombinant vaccinia. Nature 326, 878–880

3.  Rose, K.A., Stapleton, G., Dott, K., Kieny, M.P., Best, R., Schwarz, M., Russell, D.W., Björkhem, I., Seckl, J. and Lathe, R. (1997) Cyp7b hydroxylates dehydroepiandrosterone (DHEA) and pregnenolone at the 7α position. Proc. Natl. Acad. Sci. USA 94, 4925–4930

4.  Lathe, R. (2001) Hormones and the hippocampus. J. Endocrinol. 169, 205–231

5.   Lathe, R. (2004) Fast tidal cycling and the origin of life. Icarus 168, 18–22

6.   Lathe, R. (2005) Autism, Brain and Environment, Kingsley Publishers

7.  Lathe, R. and Harris, A. (2009) Differential display detects host nucleic acid motifs altered in scrapie infected brain. J Mol. Biol. 392, 813–822

8.   Lathe, R., Sapronova, A. and Kotelevtsev, Y. (2014) Atherosclerosis and Alzheimer – diseases with a common cause? Inflammation, oxysterols, vasculature. BMC Geriatr. 14, 36

9. Itzhaki, R.F., Lathe, R., and 31 others (2016) Microbes and Alzheimer's disease. J Alzheimers Dis. 51, 979–984

10. Moir, R.D., Lathe, R., and Tanzi, R.E. (2018) The antimicrobial protection hypothesis of Alzheimer's disease. Alzheimers Dement. 14, 1602–1614

11. Haas, J.G. and Lathe, R. (2018) Microbes and Alzheimer's disease: new findings call for a paradigm change. Trends Neurosci. 41, 570–573

12. Lathe, R., Singadia, S., Jordan, C., and Riedel, G. (2020) The interoceptive hippocampus: mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis. PLoS One 15, e0227575

13. Lathe, R. and Darlix, J.L. (2020) Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy. Arch Virol. 165, 535–556

14. Lathe, R. and St Clair, D. (2020) From conifers to cognition: microbes, brain, and behavior. Genes Brain Behav. 2020, e12680

Swansea academic to lead UK-Russia workshop for early career researchers in Moscow

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Dr Igor Sazonov, a researcher in Swansea University’s College of Engineering, will co-lead a British Council funded UK-Russia workshop for early career researchers in Moscow next April.

The event has been organised under the British Council Researcher Links scheme and is aimed at early career researchers with less than 10 years of post-PhD research experience.

Dr Igor Sazonov, whose Engineering expertise lies in fluid dynamics, blood flow simulation, mesh generation, geophysics, and acoustics, said: “I am delighted to lead this event in partnership with my colleague Dr Vassilevski, under the British Council Researcher Links scheme.

“The workshop will bring together early career researchers from the UK and Russia to critically assess the current state of the art and future directions in the field of mathematical and numerical cardiovascular modelling.

“It will provide an opportunity for engineers, mathematical and medical experts from both countries to share current results and developments in this field. Due to the multidisciplinary nature of the workshop, it provides an excellent opportunity to early career researchers to be enthused and nurtured.”

The workshop will also include contributions from other leading researchers in the field including  Professor Perumal Nithiarasu, Swansea University; Professor Xiaoyu Luo, Glasgow University; Professor Sergey Mukhin, M V Lomonosov Moscow State University; and Dr Rubin R Aliev, Moscow Institute for Physics and Technology.

• Posted by Bethan Evans < [email protected] >
• Friday 6 December 2013 00.00 GMT
• Wednesday 25 September 2019 11.04 BST
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