A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with an orthorhombic unit cell. The tensile properties of PLA can vary widely, depending on whether or not it is annealed or oriented or what its degree ...
(PDF) A Literature Review of Poly(Lactic Acid)
A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with ...
A Literature Review of Poly (Lactic Acid)
A Literature Review of Poly (Lactic Acid) A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with an orthorhombic unit cell. The tensile properties of PLA can vary widely, depending on whether or not it is ...
Review Polylactic acid (PLA): Properties, synthesis, and biomedical
Some synthetic polymers used in tissue engineering are poly (lactic acid) - PLA, poly (glycolic acid) - PGA, poly (ethylene glycol) - PEG, and the natural derived are collagen, hyaluronic acid, alginate, agarose, fibrin, etc. [19]. Several applications of biomaterials in tissue engineering have been reported (Table 2).
A Review on Synthesis, Properties, and Applications of Polylactic Acid
1. Introduction. Owing to its versatility and good performance, polylactic acid (PLA) as a biodegradable polymer is regarded as one of the most favorable polymers to substitute petroleum-based plastics [1,2,3].The low toughness and poor thermal stability of PLA, however, restrict the usage of PLA in applications, such as food packaging and medical implants [].
Poly(lactic Acid): A Versatile Biobased Polymer for the Future with
Furthermore, optical purity (in addition to the chemical purity) of lactide or lactic acid also has a great impact on the characteristics of poly (lactic acid). Recently, genetically engineered E. coli strains have been used to obtain optically pure lactic acid with fast growth, high yield and conversion rates using defined media to further ...
Perspectives of polylactic acid from structure to applications
Different Polylactic Acid categories include Racemic PLLA (Poly-L-lactic Acid), Regular PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), and PDLLA (Poly-DL-lactic Acid). PLA is classified as a "thermoplastic" polyester (as opposed to "thermoset"), and the name has to do with the way the plastic responds to heat.
Polymers
Environmental problems, such as global warming and plastic pollution have forced researchers to investigate alternatives for conventional plastics. Poly(lactic acid) (PLA), one of the well-known eco-friendly biodegradables and biobased polyesters, has been studied extensively and is considered to be a promising substitute to petroleum-based polymers. This review gives an inclusive overview of ...
Super tough poly(lactic acid) blends: a comprehensive review
Abstract. Poly (lactic acid) or poly (lactide) (PLA) is a renewable, bio-based, and biodegradable aliphatic thermoplastic polyester that is considered a promising alternative to petrochemical-derived polymers in a wide range of commodity and engineering applications. However, PLA is inherently brittle, with less than 10% elongation at break and ...
Tailoring of Advanced Poly(Lactic Acid)-Based Materials: A Review
Poly(lactic acid) (PLA) stands out as the most promising biodegradable alter-. native to conventional petrochemical-based polymers for manufacturing of high-performance materials applied in medicine, pharmacy, food, textile, and electronic industry. This review was aimed to present the conventional and up-to-date technologies for PLA processing ...
Synthesis of Poly(Lactic Acid): A Review
Poly (lactic acid), a bio‐degradable polymer, has been studied extensively during the past 15 years. This paper presents a review on poly (lactic acid) (PLA) with focus on its stereochemistry, synthesis via ring‐opening polymerization, reaction kinetics and thermodynamics, synthesis of low molecular weight polymer, a continuous process for ...
Review of Multifarious Applications of Poly (Lactic Acid)
This review outlines the chemical, thermal characteristics of poly (lactic acid) and discusses the use of poly (lactic acid) in medical applications such as sutures, stents, drug carrier, orthopaedic devices, scaffolds, as well as commercial applications in textile and packaging fields with superior properties such as high wicking performance ...
Synthesis of Poly(Lactic Acid): A Review
Poly (lactic acid), a bio‐degradable polymer, has been studied extensively during the past 15 years. This paper presents a review on poly (lactic acid) (PLA) with focus on its stereochemistry, synthesis via ring‐opening polymerization, reaction kinetics and thermodynamics, synthesis of low molecular weight polymer, a continuous process for ...
Synthesis, characterization of poly l(+) lactic acid and its
Poly l(+) lactic acid (PLLA) has become crucial in the biomedical industry for various uses. The direct polycondensation method was used to prepare Poly l(+) Lactic Acid (PLLA).
A Review of Poly(Lactic Acid)‐Based Materials for Antimicrobial
Poly(lactic acid) (PLA) can be synthesized from renewable bio-derived monomers and, as such, it is an alternative to conventional petroleum-based polymers. Since PLA is a relatively new polymer, much effort has been directed toward its development in order to make it an acceptable and effective option to the more traditional petroleum-based ...
Poly (Lactic Acid) Production for Tissue Engineering Applications
Poly-lactic acid Polylactic acid (PLA) is a highly versatile, biodegradable, aliphatic polyester derived from 100% renewable resources [22]. It has extensive applications in biomedical fields, including suture, bone fixation material, drug delivery microsphere, and tissue engineering [11]. Because of these properties the PLA has been widely ...
A review of poly(lactic acid)-based materials for antimicrobial
Poly(lactic acid) (PLA) can be synthesized from renewable bio-derived monomers and, as such, it is an alternative to conventional petroleum-based polymers. Since PLA is a relatively new polymer, much effort has been directed toward its development in order to make it an acceptable and effective option to the more traditional petroleum-based ...
Needle-Free Jet Injection of Poly- (Lactic Acid) for Atrophic Acne
The literature review revealed documented cases focusing on treating atrophic acne scars using intralesional poly-(lactic acid) injections. The results of these clinical studies could be supported by separate in vitro and animal studies, elucidating the feasible pathways through which this treatment operates.
An Overview of Poly(lactic- co -glycolic) Acid (PLGA)-Based ...
Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); (iii) approval for clinical use in humans by the U.S. Food and Drug Administration (FDA); (iv) potential to modify surface properties to provide better ...
Enhancing the strength and toughness of polylactic acid through fused
Simultaneously enhancing strength and toughness through simple and low‐cost methods has always been a challenge for polylactic acid (PLA) materials. In this context, natural attapulgite (ATT) nanorods were used as fillers combined with fused deposition modeling (FDM) to improve the strength and toughness of PLA. The printable PLA nanocomposite filaments filled with ATT nanorods were prepared ...
Self-Charging, Breathable, and Antibacterial Poly(lactic acid
Self-Charging, Breathable, and Antibacterial Poly(lactic acid) Nanofibrous Air Filters by Surface Engineering of Ultrasmall Electroactive Nanohybrids. Chenyu Liang. Chenyu Liang. School of Safety Engineering, China University of Mining and Technology, Xuzhou 221116, China ... To access this article, please review the available access options ...
Robust Superhydrophobic Films Based on an Eco-Friendly Poly(l-lactic
Poly(l-lactic acid) (PLLA) featuring desirable biodegradability and biocompatibility has been recognized as one of the promising eco-friendly biomaterials. However, low crystallization and poor mechanical and chemical performances dramatically hamper its practical application. In this work, we report that functionalized cellulose/PLLA composite superhydrophobic stereocomplex films with ...
Mechanical recycling of poly(lactic acid)/agave fiber biocomposites
Eselini N, Tirkes S, Akar AO, et al. Production and characterization of poly (lactic acid)-based biocomposites filled with basalt fiber and flax fiber hybrid. J Elastomers Plast 2020; 52: 701-716.
Study on the characteristics of Napier grass fibre reinforced porcelain
This study investigates the complex properties of a novel biocomposite by a conventional process, which is composed of poly (lactic acid) (PLA) as the matrix, porcelain particles as fillers, ... Shahar FS, et al. Plant fibre reinforcements as alternatives in pultruded FRP composites manufacturing: a review. J Nat Fibers 2024; 21(1): 2298396.
Effect of Monomer Sequence Distribution on the Glass Transition
Poly(lactic-co-glycolic acid) (PLGA) has garnered considerable attention as a versatile platform for the delivery of active pharmaceutical ingredients (APIs). In the field of API delivery, the glass transition temperature (Tg) is widely recognized as a fundamental predictor of drug release kinetics from PLGA formulations. Despite making significant progress in understanding the qualitative ...
A critical review of computational efforts towards identifying
Polylactic acid (PLA) may be regarded as an analogue of a poly-alanine oligo/polypeptide, where the amino group has been replaced by a hydroxyl. As a consequence, a series of studies have explored the possibility that PLA can adopt peptide-type secondary structures - i.e., repetitive structural patterns characterized by intramolecular hydrogen bonds between neighboring functional groups. To ...
Poly-L-Lactic Acid Fillers Improved Dermal Collagen Synthesis by
Poly-L-lactic acid (PLLA) fillers correct cutaneous volume loss by stimulating fibroblasts to synthesize collagen and by augmenting the volume. PLLA triggers the macrophage-induced activation of fibroblasts that secrete transforming growth factor-β (TGF-β). However, whether M2 macrophage polarization is involved in PLLA-induced collagen ...
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A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with an orthorhombic unit cell. The tensile properties of PLA can vary widely, depending on whether or not it is annealed or oriented or what its degree ...
A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with ...
A Literature Review of Poly (Lactic Acid) A literature review is presented regarding the synthesis, and physicochemical, chemical, and mechanical properties of poly (lactic acid) (PLA). Poly (lactic acid) exists as a polymeric helix, with an orthorhombic unit cell. The tensile properties of PLA can vary widely, depending on whether or not it is ...
Some synthetic polymers used in tissue engineering are poly (lactic acid) - PLA, poly (glycolic acid) - PGA, poly (ethylene glycol) - PEG, and the natural derived are collagen, hyaluronic acid, alginate, agarose, fibrin, etc. [19]. Several applications of biomaterials in tissue engineering have been reported (Table 2).
1. Introduction. Owing to its versatility and good performance, polylactic acid (PLA) as a biodegradable polymer is regarded as one of the most favorable polymers to substitute petroleum-based plastics [1,2,3].The low toughness and poor thermal stability of PLA, however, restrict the usage of PLA in applications, such as food packaging and medical implants [].
Furthermore, optical purity (in addition to the chemical purity) of lactide or lactic acid also has a great impact on the characteristics of poly (lactic acid). Recently, genetically engineered E. coli strains have been used to obtain optically pure lactic acid with fast growth, high yield and conversion rates using defined media to further ...
Different Polylactic Acid categories include Racemic PLLA (Poly-L-lactic Acid), Regular PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), and PDLLA (Poly-DL-lactic Acid). PLA is classified as a "thermoplastic" polyester (as opposed to "thermoset"), and the name has to do with the way the plastic responds to heat.
Environmental problems, such as global warming and plastic pollution have forced researchers to investigate alternatives for conventional plastics. Poly(lactic acid) (PLA), one of the well-known eco-friendly biodegradables and biobased polyesters, has been studied extensively and is considered to be a promising substitute to petroleum-based polymers. This review gives an inclusive overview of ...
Abstract. Poly (lactic acid) or poly (lactide) (PLA) is a renewable, bio-based, and biodegradable aliphatic thermoplastic polyester that is considered a promising alternative to petrochemical-derived polymers in a wide range of commodity and engineering applications. However, PLA is inherently brittle, with less than 10% elongation at break and ...
Poly(lactic acid) (PLA) stands out as the most promising biodegradable alter-. native to conventional petrochemical-based polymers for manufacturing of high-performance materials applied in medicine, pharmacy, food, textile, and electronic industry. This review was aimed to present the conventional and up-to-date technologies for PLA processing ...
Poly (lactic acid), a bio‐degradable polymer, has been studied extensively during the past 15 years. This paper presents a review on poly (lactic acid) (PLA) with focus on its stereochemistry, synthesis via ring‐opening polymerization, reaction kinetics and thermodynamics, synthesis of low molecular weight polymer, a continuous process for ...
This review outlines the chemical, thermal characteristics of poly (lactic acid) and discusses the use of poly (lactic acid) in medical applications such as sutures, stents, drug carrier, orthopaedic devices, scaffolds, as well as commercial applications in textile and packaging fields with superior properties such as high wicking performance ...
Poly (lactic acid), a bio‐degradable polymer, has been studied extensively during the past 15 years. This paper presents a review on poly (lactic acid) (PLA) with focus on its stereochemistry, synthesis via ring‐opening polymerization, reaction kinetics and thermodynamics, synthesis of low molecular weight polymer, a continuous process for ...
Poly l(+) lactic acid (PLLA) has become crucial in the biomedical industry for various uses. The direct polycondensation method was used to prepare Poly l(+) Lactic Acid (PLLA).
Poly(lactic acid) (PLA) can be synthesized from renewable bio-derived monomers and, as such, it is an alternative to conventional petroleum-based polymers. Since PLA is a relatively new polymer, much effort has been directed toward its development in order to make it an acceptable and effective option to the more traditional petroleum-based ...
Poly-lactic acid Polylactic acid (PLA) is a highly versatile, biodegradable, aliphatic polyester derived from 100% renewable resources [22]. It has extensive applications in biomedical fields, including suture, bone fixation material, drug delivery microsphere, and tissue engineering [11]. Because of these properties the PLA has been widely ...
Poly(lactic acid) (PLA) can be synthesized from renewable bio-derived monomers and, as such, it is an alternative to conventional petroleum-based polymers. Since PLA is a relatively new polymer, much effort has been directed toward its development in order to make it an acceptable and effective option to the more traditional petroleum-based ...
The literature review revealed documented cases focusing on treating atrophic acne scars using intralesional poly-(lactic acid) injections. The results of these clinical studies could be supported by separate in vitro and animal studies, elucidating the feasible pathways through which this treatment operates.
Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); (iii) approval for clinical use in humans by the U.S. Food and Drug Administration (FDA); (iv) potential to modify surface properties to provide better ...
Simultaneously enhancing strength and toughness through simple and low‐cost methods has always been a challenge for polylactic acid (PLA) materials. In this context, natural attapulgite (ATT) nanorods were used as fillers combined with fused deposition modeling (FDM) to improve the strength and toughness of PLA. The printable PLA nanocomposite filaments filled with ATT nanorods were prepared ...
Self-Charging, Breathable, and Antibacterial Poly(lactic acid) Nanofibrous Air Filters by Surface Engineering of Ultrasmall Electroactive Nanohybrids. Chenyu Liang. Chenyu Liang. School of Safety Engineering, China University of Mining and Technology, Xuzhou 221116, China ... To access this article, please review the available access options ...
Poly(l-lactic acid) (PLLA) featuring desirable biodegradability and biocompatibility has been recognized as one of the promising eco-friendly biomaterials. However, low crystallization and poor mechanical and chemical performances dramatically hamper its practical application. In this work, we report that functionalized cellulose/PLLA composite superhydrophobic stereocomplex films with ...
Eselini N, Tirkes S, Akar AO, et al. Production and characterization of poly (lactic acid)-based biocomposites filled with basalt fiber and flax fiber hybrid. J Elastomers Plast 2020; 52: 701-716.
This study investigates the complex properties of a novel biocomposite by a conventional process, which is composed of poly (lactic acid) (PLA) as the matrix, porcelain particles as fillers, ... Shahar FS, et al. Plant fibre reinforcements as alternatives in pultruded FRP composites manufacturing: a review. J Nat Fibers 2024; 21(1): 2298396.
Poly(lactic-co-glycolic acid) (PLGA) has garnered considerable attention as a versatile platform for the delivery of active pharmaceutical ingredients (APIs). In the field of API delivery, the glass transition temperature (Tg) is widely recognized as a fundamental predictor of drug release kinetics from PLGA formulations. Despite making significant progress in understanding the qualitative ...
Polylactic acid (PLA) may be regarded as an analogue of a poly-alanine oligo/polypeptide, where the amino group has been replaced by a hydroxyl. As a consequence, a series of studies have explored the possibility that PLA can adopt peptide-type secondary structures - i.e., repetitive structural patterns characterized by intramolecular hydrogen bonds between neighboring functional groups. To ...
Poly-L-lactic acid (PLLA) fillers correct cutaneous volume loss by stimulating fibroblasts to synthesize collagen and by augmenting the volume. PLLA triggers the macrophage-induced activation of fibroblasts that secrete transforming growth factor-β (TGF-β). However, whether M2 macrophage polarization is involved in PLLA-induced collagen ...