Case Study: A 68-Year-Old Man With Diabetes and Peripheral Neuropathy
It is estimated that 60-100% of the diabetic population has some form of neuropathy, ranging from barely detectable asymptomatic neuropathy to severe disabling painful disease to dense anesthesia. Few doubt that duration and degree of hyperglycemia are the major culprits, although the mechanisms involved are complex, not adequately or ...
Diabetic Peripheral Neuropathic Pain: Case Studies
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetic neuropathy occurring in patients with diabetes mellitus ...
Diabetic Neuropathic Cachexia: A Clinical Case and Review of Literature
After clinical evaluation and a nerve conduction study, diagnosis of diabetic cachectic neuropathy was made based on the rapid onset of severe neuropathic pain in the context of diabetic neuropathy, marked weight loss, and depressed mood. ... We herein report a recent case of diabetic neuropathic cachexia and compare it to previous cases in the ...
Diabetic neuropathy: Clinical manifestations and current treatments
Diabetic peripheral neuropathy is a prevalent, disabling condition. The most common manifestation is a distal symmetric polyneuropathy (DSP), but many patterns of nerve injury can occur. Currently, the only effective treatments are glucose control and pain management. While glucose control dramatically decreases the development of neuropathy in ...
Diabetic neuropathy
Diabetic neuropathy is a complication of diabetes mellitus that results in loss of sensory function beginning in the extremities. This Primer summarizes the epidemiology, mechanisms, diagnosis and ...
Diabetic Peripheral Neuropathic Pain: Case Studies
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetic neuropathy occurring in patients with diabetes mellitus ...
Acute diabetic neuropathy following improved glycaemic control: a case
Summary We present three cases of acute diabetic neuropathy and highlight a potentially underappreciated link between tightening of glycaemic control and acute neuropathies in patients with diabetes. Case 1: A 56-year-old male with poorly controlled type 2 diabetes (T2DM) was commenced on basal-bolus insulin. He presented 6 weeks later with a diffuse painful sensory neuropathy and postural ...
A 23-year-old woman diagnosed with type 1 diabetes mellitus in 2011 came to our outpatient office because of an inability to walk correctly. She was under a basal bolus insulin regimen. In the summer of 2016, she experienced a rapid improvement in her glycaemic control. A few weeks later, she started to complain of a severe burning pain in the soles of her feet (pain score 10/10). Neither ...
Pain in diabetic neuropathy case study: whole patient management
Painful diabetic peripheral neuropathy (DPN) is described as a superficial burning pain associated with other positive and/or negative sensory systems affecting the feet and lower extremities. ... Pain in diabetic neuropathy case study: whole patient management Eur J Neurol. 2004 Apr:11 Suppl 1:12-21. doi: 10.1111/j.1471-0552.2004.00795.x ...
Frontiers
Diabetic peripheral neuropathy is the most prevalent chronic complication of diabetes and is based on sensory and autonomic nerve symptoms. ... In this study, patients with refractory diabetic peripheral neuropathy have been treated with different hypoglycemic and vegetative nerve regimens. ... as a small case report, this study is reasonable ...
Diabetic peripheral neuropathic pain: case studies
Abstract. Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetlc ...
Pain in diabetic neuropathy case study: whole patient management
Current treatment options for DPN include mainly antidepressants and anticonvulsants, with other agents such as tramadol, dextromethorphan and memantine being employed or studied. This review article includes a case study of a patient with painful DPN to demonstrate the current management strategies for this neuropathic pain syndrome.
Diabetic neuropathy (Chapter 8)
Case Studies in Pain Management - October 2014. ... Chapter 8 - Diabetic neuropathy. from Section 1 - Neurological Disorders. Published online by Cambridge University Press: 05 October 2014 By. Gulshan Doulatram and. Tilak Raj. Edited by. Alan David Kaye and. Rinoo V. Shah. Show author details
PDF Case Presentation: Neuropathic Pain History
Diabetic neuropathy can all types of neurons including sensory, motor, or autonomic. When sensory neurons are affected, symptoms can include ... Peripheral neuropathic pain synromes: three case studies. JCOM 2004; 11(11): 729-740. 13. Afilalo M, Morlion B. Efficacy of tapentadol ER for managing moderate to severe chronic pain. Pain Physician ...
Diabetic neuropathy
Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. High blood sugar (glucose) can injure nerves throughout the body. Diabetic neuropathy most often damages nerves in the legs and feet. Depending on the affected nerves, diabetic neuropathy symptoms include pain and numbness in the legs, feet and hands.
Diabetic neuropathy
Exercise is emerging as a promising prevention strategy in diabetic neuropathy. One study demonstrated increased distal leg IENFD by 1.5 fibres mm −1 in patients with diabetes (without neuropathy) who received a weekly structured and supervised exercise programme, but IENFD was unchanged in patients who received lifestyle counselling (−0.1 ...
Association Between HbA1c Levels and Diabetic Peripheral Neuropathy: A
Objective: The objective of this study was to explore factors associated with DPN, including long-term HbA1c parameters, among patients with type 2 diabetes, in a large-scale longitudinal study. Methods: We conducted a case-control study using a medical claims database. We extracted data of patients with type 2 diabetes and disease records of ...
Association Between HbA1c Levels and Diabetic Peripheral Neuropathy: A
Background Evidence on the efficacy of glycemic control for diabetic peripheral neuropathy (DPN) is limited in patients with type 2 diabetes mellitus. Despite the known relationship between hemoglobin A1c (HbA1c) and DPN, the parameters (e.g., mean values or variability) that play an important role have not been elucidated. Objective The objective of this study was to explore factors ...
Diabetic neuropathy: A narrative review of risk factors, classification
1. Definition and risk factors. Diabetic neuropathy (DN) may be defined as the presence of certain signs or specific symptoms and suggestive for neuropathy in patients with diabetes mellitus (DM), after excluding other possible causes of neuronal damage ().DN is the most common microvascular complication encountered in DM individuals; after 20 years of disease progression, more than 50% of DM ...
Diabetic Neuropathic Pain: Which Treatments Work?
Diabetic neuropathy (DN) treatments like alpha-lipoic acid are not reimbursed in France, making access difficult. ... The 2020 recommendations from the French Society for the Study and Treatment ...
Sensors
In this study, vibrating insoles were therapeutically used by 22 participants, for 30 min per day, on a daily basis, for a month by persons with diabetic sensory peripheral neuropathy. The therapeutic application of vibrating insoles in this cohort significantly improved VPT by an average of 8.5 V (p = 0.001) post-intervention and 8.2 V (p < 0. ...
Fracture Risk Tied to Microvascular Diseases in Type 2 Diabetes
May 15, 2024. Compared with patients with only type 2 diabetes, those with type 2 diabetes and microvascular disease had an elevated fracture risk. Type 2 diabetes with microvascular diseases, especially neuropathy, are associated with higher risks for fracture, according to study results presented at the 24th Edition of the World Congress on ...
Neuropathy very common, underdiagnosed
One-half of the people had diabetes, which can cause neuropathy. A total of 67% had metabolic syndrome, which is defined as having excess belly fat plus two or more of the following risk factors ...
Health and Productivity Benefits with Early Intensified Treatment in
The steady increase of diabetes mellitus (DM) prevalence has triggered an important socioeconomic burden worldwide. In 2019, the age-adjusted prevalence of DM in Korea was estimated at 3.7 million patients. 1 Amongst diabetes types, the most common is Type 2 diabetes mellitus (T2DM) which accounts for approximately 90% of all diabetes cases, globally. 2,3 Diabetes patients are at high risk of ...
Neuropathy very common, but underdiagnosed, study says
The study presents an "incredible opportunity" to raise awareness that neuropathy is "a common consequence" of metabolic syndrome, including diabetes, obesity, abnormal blood lipids and high blood ...
Case report: patient's perspective on acute diabetic neuropathy
Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, LaMoreaux L, Garofalo E. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA. 1998 Dec 2;280(21):1831-1836.
Genetic markers of cardiac autonomic neuropathy in the Kazakh
Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that increases the risk of morbidity and mortality by disrupting cardiac innervation. Recent evidence suggests that CAN may manifest even before the onset of DM, with prediabetes and metabolic syndrome potentially serving as precursors. This study aims to identify genetic markers associated with CAN development in ...
Feeling pins & needles in your hands or feet could reveal concerning
These patients had an average age of 58, and two-thirds were Black. Half of the study group also had diabetes, which researchers note can cause neuropathy. ... only 54 percent had a case of neuropathy. After taking various factors into account, the study authors say someone with metabolic syndrome is four times more likely to develop this type ...
COMMENTS
It is estimated that 60-100% of the diabetic population has some form of neuropathy, ranging from barely detectable asymptomatic neuropathy to severe disabling painful disease to dense anesthesia. Few doubt that duration and degree of hyperglycemia are the major culprits, although the mechanisms involved are complex, not adequately or ...
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetic neuropathy occurring in patients with diabetes mellitus ...
After clinical evaluation and a nerve conduction study, diagnosis of diabetic cachectic neuropathy was made based on the rapid onset of severe neuropathic pain in the context of diabetic neuropathy, marked weight loss, and depressed mood. ... We herein report a recent case of diabetic neuropathic cachexia and compare it to previous cases in the ...
Diabetic peripheral neuropathy is a prevalent, disabling condition. The most common manifestation is a distal symmetric polyneuropathy (DSP), but many patterns of nerve injury can occur. Currently, the only effective treatments are glucose control and pain management. While glucose control dramatically decreases the development of neuropathy in ...
Diabetic neuropathy is a complication of diabetes mellitus that results in loss of sensory function beginning in the extremities. This Primer summarizes the epidemiology, mechanisms, diagnosis and ...
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetic neuropathy occurring in patients with diabetes mellitus ...
Summary We present three cases of acute diabetic neuropathy and highlight a potentially underappreciated link between tightening of glycaemic control and acute neuropathies in patients with diabetes. Case 1: A 56-year-old male with poorly controlled type 2 diabetes (T2DM) was commenced on basal-bolus insulin. He presented 6 weeks later with a diffuse painful sensory neuropathy and postural ...
A 23-year-old woman diagnosed with type 1 diabetes mellitus in 2011 came to our outpatient office because of an inability to walk correctly. She was under a basal bolus insulin regimen. In the summer of 2016, she experienced a rapid improvement in her glycaemic control. A few weeks later, she started to complain of a severe burning pain in the soles of her feet (pain score 10/10). Neither ...
Painful diabetic peripheral neuropathy (DPN) is described as a superficial burning pain associated with other positive and/or negative sensory systems affecting the feet and lower extremities. ... Pain in diabetic neuropathy case study: whole patient management Eur J Neurol. 2004 Apr:11 Suppl 1:12-21. doi: 10.1111/j.1471-0552.2004.00795.x ...
Diabetic peripheral neuropathy is the most prevalent chronic complication of diabetes and is based on sensory and autonomic nerve symptoms. ... In this study, patients with refractory diabetic peripheral neuropathy have been treated with different hypoglycemic and vegetative nerve regimens. ... as a small case report, this study is reasonable ...
Abstract. Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetlc ...
Current treatment options for DPN include mainly antidepressants and anticonvulsants, with other agents such as tramadol, dextromethorphan and memantine being employed or studied. This review article includes a case study of a patient with painful DPN to demonstrate the current management strategies for this neuropathic pain syndrome.
Case Studies in Pain Management - October 2014. ... Chapter 8 - Diabetic neuropathy. from Section 1 - Neurological Disorders. Published online by Cambridge University Press: 05 October 2014 By. Gulshan Doulatram and. Tilak Raj. Edited by. Alan David Kaye and. Rinoo V. Shah. Show author details
Diabetic neuropathy can all types of neurons including sensory, motor, or autonomic. When sensory neurons are affected, symptoms can include ... Peripheral neuropathic pain synromes: three case studies. JCOM 2004; 11(11): 729-740. 13. Afilalo M, Morlion B. Efficacy of tapentadol ER for managing moderate to severe chronic pain. Pain Physician ...
Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. High blood sugar (glucose) can injure nerves throughout the body. Diabetic neuropathy most often damages nerves in the legs and feet. Depending on the affected nerves, diabetic neuropathy symptoms include pain and numbness in the legs, feet and hands.
Exercise is emerging as a promising prevention strategy in diabetic neuropathy. One study demonstrated increased distal leg IENFD by 1.5 fibres mm −1 in patients with diabetes (without neuropathy) who received a weekly structured and supervised exercise programme, but IENFD was unchanged in patients who received lifestyle counselling (−0.1 ...
Objective: The objective of this study was to explore factors associated with DPN, including long-term HbA1c parameters, among patients with type 2 diabetes, in a large-scale longitudinal study. Methods: We conducted a case-control study using a medical claims database. We extracted data of patients with type 2 diabetes and disease records of ...
Background Evidence on the efficacy of glycemic control for diabetic peripheral neuropathy (DPN) is limited in patients with type 2 diabetes mellitus. Despite the known relationship between hemoglobin A1c (HbA1c) and DPN, the parameters (e.g., mean values or variability) that play an important role have not been elucidated. Objective The objective of this study was to explore factors ...
1. Definition and risk factors. Diabetic neuropathy (DN) may be defined as the presence of certain signs or specific symptoms and suggestive for neuropathy in patients with diabetes mellitus (DM), after excluding other possible causes of neuronal damage ().DN is the most common microvascular complication encountered in DM individuals; after 20 years of disease progression, more than 50% of DM ...
Diabetic neuropathy (DN) treatments like alpha-lipoic acid are not reimbursed in France, making access difficult. ... The 2020 recommendations from the French Society for the Study and Treatment ...
In this study, vibrating insoles were therapeutically used by 22 participants, for 30 min per day, on a daily basis, for a month by persons with diabetic sensory peripheral neuropathy. The therapeutic application of vibrating insoles in this cohort significantly improved VPT by an average of 8.5 V (p = 0.001) post-intervention and 8.2 V (p < 0. ...
May 15, 2024. Compared with patients with only type 2 diabetes, those with type 2 diabetes and microvascular disease had an elevated fracture risk. Type 2 diabetes with microvascular diseases, especially neuropathy, are associated with higher risks for fracture, according to study results presented at the 24th Edition of the World Congress on ...
One-half of the people had diabetes, which can cause neuropathy. A total of 67% had metabolic syndrome, which is defined as having excess belly fat plus two or more of the following risk factors ...
The steady increase of diabetes mellitus (DM) prevalence has triggered an important socioeconomic burden worldwide. In 2019, the age-adjusted prevalence of DM in Korea was estimated at 3.7 million patients. 1 Amongst diabetes types, the most common is Type 2 diabetes mellitus (T2DM) which accounts for approximately 90% of all diabetes cases, globally. 2,3 Diabetes patients are at high risk of ...
The study presents an "incredible opportunity" to raise awareness that neuropathy is "a common consequence" of metabolic syndrome, including diabetes, obesity, abnormal blood lipids and high blood ...
Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, LaMoreaux L, Garofalo E. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA. 1998 Dec 2;280(21):1831-1836.
Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that increases the risk of morbidity and mortality by disrupting cardiac innervation. Recent evidence suggests that CAN may manifest even before the onset of DM, with prediabetes and metabolic syndrome potentially serving as precursors. This study aims to identify genetic markers associated with CAN development in ...
These patients had an average age of 58, and two-thirds were Black. Half of the study group also had diabetes, which researchers note can cause neuropathy. ... only 54 percent had a case of neuropathy. After taking various factors into account, the study authors say someone with metabolic syndrome is four times more likely to develop this type ...