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Microbiology Department Dissertations Collection

Dissertations from 2024 2024.

DEVELOPMENT OF ACIDIFIED OIL-BASED ANTIMICROBIALS FOR DRY CLEANING AGAINST SALMONELLA ENTERICA AND STUDYING THE EVOLUTION OF ITS ACID ADAPTATION , Mrinalini Ghoshal, Microbiology

Dissertations from 2023 2023

A Biochemical Approach to Characterize a Divergent Trypanosoma brucei Mitochondrial DNA Polymerase, POLIB , Stephanie B. Delzell, Microbiology

BORRELIA BURGDORFERI: DRUG TESTING, ASSAY DEVELOPMENT, AND THE ROLE OF SERUM-MEDIATED KILLING IN THE INFECTIVITY PHENOTYPE , Patrick Pearson, Microbiology

A SHIFT IN RNA FATE: INVESTIGATING THE ROLE OF C19ORF66 DURING KSHV LYTIC REPLICATION , William Rodriguez Jr., Microbiology

Dissertations from 2022 2022

Community Assembly and Stress Response of Grassland Phyllosphere Bacteria , Emily Bechtold, Microbiology

THE SOS RESPONSE IN ESCHERICHIA COLI K12: AN EXPLORATION OF MUTATIONS IN LEXA AND RECA USING FLUORESCENCE MICROSCOPY , Steven Van Alstine, Microbiology

Dissertations from 2021 2021

PHYSIOLOGICAL CONSTRAINTS, MECHANISMS, AND MINERAL TRANSFORMATIONS OF IRON REDUCTION IN HYPERTHERMOPHILIC CRENARCHAEA , Srishti Kashyap, Microbiology

Mycobacterial Morphology and Cell Envelope: Construction and Maintenance , Emily Sarah Melzer, Microbiology

Dissertations from 2020 2020

STRUCTURE FUNCTION ANALYSIS OF MITOCHONDRIAL DNA POLYMERASE IC REVEALS MULTIPLE ROLES IN KINETOPLAST MAINTENANCE , Jonathan Miller, Microbiology

Dissertations from 2019 2019

BACTERIAL BIOTRANSFORMATION OF LIGNIN IN ANOXIC ENVIRONMENTS , Gina M. Chaput, Microbiology

The Influence of Amazon Deforestation in Brazil on the Soil Microbial Community Composition and Active Methane-Cycling , Marie Kroeger, Microbiology

THE SPATIAL ORGANIZATION OF MYCOBACTERIAL MEMBRANE , Julia Puffal, Microbiology

REGULATION OF LIPOMANNAN AND LIPOARABINOMANNAN BIOSYNTHESIS IN MYCOBACTERIA , Kathryn Rahlwes, Microbiology

NASCENT DNA PROTEOMICS ANALYSIS UNCOVERS DNA REPLICATION DYNAMICS IN THE HUMAN PATHOGEN TRYPANOSOMA BRUCEI , Maria Rocha Granados, Microbiology

Protein Degradation Regulates Phospholipid Biosynthetic Gene Expression in Saccharomyces cerevisiae , Bryan Salas-Santiago, Microbiology

Dissertations from 2018 2018

Dissecting regulatory mechanisms of ComA-dependent and ComA-independent quorum sensing pathways in Bacillus subtilis , Emily Roy, Microbiology

HYDROGEN STRESS AND SYNTROPHY OF HYPERTHERMOPHILIC HETEROTROPHS AND METHANOGENS , Begum Topcuoglu, Microbiology

Dissertations from 2017 2017

The Effects of Anthropogenic Stress on Nitrogen-Cycling Microbial Communities in Temperate and Tropical Soils , George S. Hamaoui Jr., Microbiology

Intracellular Membrane Organization in Mycobacteria , Jennifer Hayashi, Microbiology

Dissertations from 2016 2016

Conversion of Cellulose to Ethanol by the Biofuels Microbe Clostridium Phytofermentans: Quantification of Growth and Role of an Rnf-Complex in Energy Conservation , Jesús G. Alvelo-Maurosa, Microbiology

Expansion of and reclassification within the family Lachnospiraceae , Kelly N. Haas, Microbiology

Transcription Regulation of PHO5 Gene by the Ino2p and Ino4p bHLH Proteins in Saccharomyces cerevisiae , Ying He, Microbiology

Control of Proteolysis during the Caulobacter Cell Cycle , Joanne Lau, Microbiology

Dissertations from 2015 2015

Agricultural Waste Remediation and H2 Production by Hyperthermophilic Heterotrophs: Bioinformatics, Taxonomy, and Physiology , Sarah A. Hensley, Microbiology

Mechanisms for Extracellular Electron Exchange by Geobacter Species , Jessica A. Smith, Microbiology

Energetic Limitations Of Thermophilic Methanogens And Thiosulfate Reducers In The Subsurface Biosphere At Deep-Sea Hydrothermal Vents , Lucy C. Stewart, Microbiology

Dissertations from 2014 2014

Anaerobic Microbes and Communities In the Context of Soil and the Equine Digestive Tract , Amy Biddle, Microbiology

MICROBE-MINERAL RELATIONSHIPS AND BIOGENIC MINERAL TRANSFORMATIONS IN ACTIVELY VENTING DEEP-SEA HYDROTHERMAL SULFIDE CHIMNEYS , TZIHSUAN J. LIN, Microbiology

PHYSIOLOGICAL MODELS OF GEOBACTER SULFURREDUCENS AND DESULFOBACTER POSTGATEI TO UNDERSTAND URANIUM REMEDIATION IN SUBSURFACE SYSTEMS , Roberto Orellana, Microbiology

Dissertations from 2013 2013

Validation Of A Novel Vaccine Delivery System for Chlamydia Trachomatis Using Recombinant Gas Vesicles Derived From Halobacterium Salinarium , Tawanna Sabrina Childs, Microbiology

Analysis of the Spatiotemporal Localization of Mitochondrial DNA Polymerases of Trypanosoma brucei , Jeniffer Concepcón-Acevedo, Microbiology

Reca Dynamics & the SOS Response in Escherichia Coli: Cellular Limitation of Inducing Filaments , Shawn Christopher Massoni, Microbiology

Indentification of Metabolic Constraints in Clostridium Phytofermentans Using Experimental Evolution and Metabolic Flux Analysis , Supratim Mukherjee, Microbiology

Evidence of an Infectious Asthma Phenotype: Chlamydia Driven Allergy and Airway Hyperresponsiveness in Pediatric Asthma , Katir Kirit Patel, Microbiology

Microbial Community Composition and the Effects of Trace Elements on Methanogenesis Associated with Deep Subsurface Coal , Burcu Unal, Microbiology

Dissertations from 2012 2012

Universidade De Sao Paulo Centro De Energia Nuclear Na Agricultura: Soil Microbiota Related To Carbon, Nitrogen And Greenhouse Gas Cycles Across Different Land Uses In Southwestern Amazonia , Daniel Renato Lammel, Microbiology

Universidade de São Paulo Centro de Energia Nuclear na Agricultura: Soil microbiota related to carbon, nitrogen and greenhouse gas cycles across different land uses in Southwestern Amazonia , Daniel Renato Lammel

Dissertations from 2011 2011

Investigation of a sulfur-utilizing perchlorate-reducing bacterial consortium , Teresa Anne Conneely

Investigation of a Sulfur-Utilizing Perchlorate-Reducing Bacterial Consortium , Teresa Anne Conneely, Microbiology

Discrete steps in the entry pathway and disassembly of SV40 , Dmitry Kuksin

Discrete Steps In The Entry Pathway And Disassembly Of SV40 , Dmitry Kuksin, Microbiology

Regulation Of The Saccharomyces Cerevisiae INO1 Gene: Novel Insights Into A Hallmark Of Eukaryotic Transcription Regulation , Ameet S Shetty, Microbiology

Regulation of the Saccharomyces cerevisiae INO1 gene: Novel insights into a hallmark of eukaryotic transcription regulation , Ameet S Shetty

Better, Faster, Stronger: Evolving Geobacter Species For Enhanced Capabilities , Zarath M Summers, Microbiology

Better, faster, stronger: Evolving Geobacter species for enhanced capabilities , Zarath M Summers

Growth Kinetics and Constraints Related to Metabolic Diversity and Abundances of Hyperthermophiles in Deep-Sea Hydrothermal Vents , Helene Chavanne Ver Eecke, Microbiology

Dissertations from 2010 2010

Role of Sulfate-Reducing Bacteria in the Attenuation of Acid Mine Drainage through Sulfate and Iron Reduction , Caryl Ann Becerra, Microbiology

Dissertations from 2009 2009

The SOS response in Escherichia coli: Single cell analysis using fluorescence microscopy , Jarukit E Long

The SOS Response In Escherichia Coli: Single Cell Analysis Using Fluorescence Microscopy , Jarukit E Long, Microbiology

Investigation of Fe(III) Reduction in Geobacter Sulfurreducens Characterization of Outer Surface Associated Electron Transfer Components , Xenlei Qian, Microbiology

Dissertations from 2008 2008

Genetic studies of replication restart in Escherichia coli , Ruethairat Boonsombat

Characterization of the carbon dioxide assimilation pathways in the hyperthermophilic archaeon Pyrobaculum islandicum , Yajing Hu

Oxidative stress responses in Escherichia coli and Pseudomonas aeruginosa , Wanilada Rungrassamee

Dissertations from 2007 2007

Cellulose degradation and biofilm formation in the developmental life cycle of the cellulolytic actinomycete Thermobifida fusca , Almaris N Alonso

Dissimilatory iron reduction in the hyperthermophilic Archaea Pyrobaculum , Lawrence Frederick Feinberg

Patterns of community change of archaeal and bacterial populations colonizing extreme environments at Kilauea Volcano, Hawaii , Vicente Gomez-Alvarez

Microbial communities involved in the nitrogen cycle at the soil aggregate scale , Javier A Izquierdo

Evaluation of the transfer of Listeria monocytogenes: A study at the macroscopic and cellular level , Andres Rodriguez Lozano

Dissertations from 2006 2006

Investigation of electron transport proteins in the Geobacteraceae , Jessica Erin Butler

Evaluation of outer-surface proteins in the reduction of iron(III) oxide in Geobacter sulfurreducens , Teena Mehta

Influence of plant-associated microbial communities on heavy metal uptake by the aquatic plant Lemna minor , Lisa M Stout

Quantification of Vibrio vulnificus in shellfish by conventional *PCR and real time PCR , Shishan Wang

Dissertations from 2005 2005

Understanding genome structure, function, and evolution in the halophilic archaeon Halobacterium NRC-1 , Sean P Kennedy

Dissertations from 2003 2003

The significance of iron(III) reducing bacteria in uranium(VI) bioremediation and energy production by sediment fuel cells , Dawn Elena Holmes

Replication restart in Escherichia coli: Genetic studies at the interface of recombination and replication , Jesse Daniel McCool

Chlamydia-host cell interactions: Studies of lipid rafts, caveolin proteins, the glycolipid exoantigen (GLXA) and intermediate filament proteins , Wilmore Christopher Webley

Dissertations from 2002 2002

Novel anaerobic bioremediation strategies for organic and metal contaminants , Kevin Thomas Finneran

Mechanisms of iron(III) oxide reduction in the environment and in pure culture , Kelly Patricia Nevin

The role of notch signaling in regulating nuclear hormone receptor activity in mammalian T lymphocytes and Drosophila , Tanapat Palaga

Anaerobic metabolism of organic compounds by hyperthermophilic microorganisms , Jason M Tor

Serum xanthine oxidoreductase: Hydrogen peroxide production rates in mammalian sera , Andrew D. G Van Praagh

Phenotypic and genomic characteristics of members of the “Burkholderia cepacia complex” , Fude Yao

Characterization of the quorum -sensing system of a biocontrol strain Burkholderia ambifaria from maize rhizosphere , Hongwei Zhou

Dissertations from 2001 2001

Embryogenesis in Arabidopsis thaliana: Mutant library construction and embryo mutant identification and characterization , Qi Hall

Degradation of naphthalene and phenanthrene in contaminated marine sediments under sulfate reducing conditions , Lory Ann Hayes

Gene products from Bacillus megaterium involved in the metabolism of polyhydroxyalkanoic acid (PHA) and the biogenesis of PHA inclusion -bodies , Gabriel J McCool

Immunoglobulin gene diversification and B-cell ontogeny in cattle , Saiju Pyarajan

Chitin degradation by the facultatively aerobic cellulolytic bacterium Cellulomonas uda , Gemma Reguera

Dissertations from 2000 2000

The bop gene regulon , Nitin S Baliga

Isolation and characterization of multicytochrome gene cluster from Shewanella putrefaciens MR-1 involved in iron and manganese reduction , Alexander S Beliaev

Regulation of the p53 tumor suppressor gene in the mammary gland and its role in tumorigenesis , Charlotte Kuperwasser

Flux of poly(hydroxyalkanoates) in photosynthetic benthic microbial mats , Mary M Rothermich

Expression and processing of xanthin dehydrogenase/oxidase cDNA from African cape buffalo , Jun Wang

Characterization of the sperm factor responsible for initiating [calcium (2+)](i) oscillations during fertilization in mammalian eggs , Hua Wu

Microtubule organization, movement and turnover in motile and non-motile cells , Anne-Marie C Yvon

Dissertations from 1999 1999

Development of a system for genetic exchange and studies of genome structure and fermentation pathways in Clostridium papyrosolvens C7 , Jiancai He

Bacterial production and extracellular degradation of polyesters , Robin Jeanne Quinteros

Dissertations from 1998 1998

Genetic analysis of two mutants altered with respect to formation of polyhydroxyalkanoic acid and identification of putative RNA helicase, nuclease and gas vesicle genes in Bacillus megaterium , Ning Li

Identification and characterization of a cryptic D-serine deaminase (DSD) gene from Burkholderia cepacia , Stacy O Montgomery

Dissertations from 1997 1997

Characterization of a novel baculovirus, gonad-specific virus, GSV , Hua Lu

Dissertations from 1996 1996

RNA-dependent RNA polymerase of turnip crinkle virus and the effect of coat protein on the replication of subviral RNAs , Jong-Won Oh

Dissertations from 1993 1993

Production and characterization of anti-idiotypic antibodies, biological mimicry of a glycolipid exoantigen of Chlamydia trachomatis in vivo , Ling-Ling An

Dissertations from 1926 1926

Physiological studies in cellulose fermentation , J. Raymond Sanborn, Microbiology

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Microbiology and Infectious Diseases

Master of Science (MSc)

Thesis-based program

Program overview.

The Microbiology and Infectious Diseases Master's program provides students with a strong foundation for doctoral studies while opening many research-oriented career options. Faculty research ranges from lung infections in cystic fibrosis and systemic infections such as sepsis to molecular diagnostics and therapeutics and vaccine development. The program is associated with several research groups, including the Immunology, Bacterial Pathogenesis and Gastrointestinal Research Group, as well as the Inflammation Research Network. Ambitious students will find many opportunities for cross-disciplinary collaboration, and will enjoy studying in the heart of a vibrant, young city that is one of the cleanest in the world and on the doorstep of Alberta's Rocky Mountains.

Completing this program

Courses: Topics may include medical microbiology and microbial diseases, gene expression in bacteria and others.

Research Ethics:  Students are required to attend Research Integrity Day sessions in the first year of their program.

• Sex & Gender Module: Students are required to complete one of the CIHR sex and gender online training modules found at discoversexandgender.ca in the first year of their program.

Seminar: Students will present an annual seminar in an applicable research group.

Research proposal: Students must defend a written research proposal to their supervisory committee.

Thesis:  Students will be required to submit and defend an original research thesis.

Pharmaceutical industry – researcher, project manager; Academia, including post-doctoral research; Government, Clinical Microbiology, Consulting, Alberta Health Services.

A master’s degree in microbiology and infectious disease will give you the pre-requisite for a PhD.

Students are required to prepare a thesis and successfully defend in an open oral defense.

Two courses

Learn more about program requirements in the Academic Calendar

Classroom delivery

Time commitment.

Two years full time; four years maximum

A supervisor is required, and must agree to oversee the student's research before the student applies for admission

See the Graduate Calendar for information on  fees and fee regulations,  and for information on  awards and financial assistance .

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Explore the University of Calgary’s (UCalgary) Foothills Campus from anywhere. Experience all that the Cumming School of Medicine has to offer for interested prospective graduate students. Explore this state of the art campus from wherever you are. Discover the buildings, student services and available programs all from your preferred device.

Supervisors

Learn about faculty available to supervise this degree.

George Chaconas

Eduardo Cobo

Carla Coffin

Jennifer Corcoran

Jeroen De Buck

Rebekah DeVinney

Craig Jenne

Nargis Khan

Douglas Mahoney

Michael Parkins

Admission Requirements

A minimum of 3.3 GPA on a 4.0 point system, over the past two years of full-time study (a minimum of 10 full-course equivalents or 60 units) of the undergraduate degree.

Minimum education

A four year baccalaureate degree, or equivalent from a recognized institution.

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Reference letters, test scores, english language proficiency.

An applicant whose primary language is not English may fulfill the English language proficiency requirement in one of the following ways:

• Test of English as a Foreign Language (TOEFL ibt)  score of 105.
• International English Language Testing System (IELTS)  score of 7.5 (minimum of 7.0 in each section)
• Pearson Test of English (PTE)   score of 75, or higher (Academic version).
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• Academic Communication Certificate (ACC)  score of A- in each course.
• Cambridge C1 Advanced or Cambridge C2 Proficiency  minimum score of 200.
• Duolingo English Test  and obtaining a minimum score of 145* (with no sub-score below 125*). ( temporary until Fall 2024 intake )

For admission on May 1:

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• International students: Dec. 1 application deadline

For admission on September 1:

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• International students: Apr. 1 application deadline

For admission on January 1:

• Canadians and permanent residents: Oct. 1 application deadline
• International students: Aug. 1 application deadline

If you're not a Canadian or permanent resident, or if you have international credentials, make sure to learn about international requirements

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Learn more about this program, microbiology, immunology and infectious diseases.

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Related programs

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Biological Sciences

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Gastrointestinal Sciences

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Digital Commons @ USF > College of Arts and Sciences > Molecular Biosciences > Theses and Dissertations

Molecular Biosciences Theses and Dissertations

Theses/dissertations from 2023 2023.

Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta , Celine Grace F. Atkinson

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression , Janine M. DeBlasi

Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53 , Emily Gregory

Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer , Allan E. Gutierrez

Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity , Daniel K. Lester

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML , Christopher T. Letson

Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response , Baylie M. Schott

Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function , January M. Watters

Theses/Dissertations from 2022 2022

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans , Lindsey N. Barrett

Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3 , Alycia Gardner

Cell-free DNA Methylation Signatures in Cancer Detection and Classification , Jinyong Huang

The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation , Kenneth D. Maus

A Holistic Investigation of Acidosis in Breast Cancer , Bryce Ordway

Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars , Alyssa N. Smith

Theses/Dissertations from 2021 2021

Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance , Jessie L. Allen

Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology , Ravneet Kaur Chhabra

Ecology and diversity of boletes of the southeastern United States , Arian Farid

CircREV1 Expression in Triple-Negative Breast Cancer , Meagan P. Horton

Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy , Sarah J. Kennedy

The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans , Doreen Ikhuva Lugano

Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus , Stephanie M. Marroquin

Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia , Emily M. Mayo

Transcriptomic and Functional Investigation of Bacterial Biofilm Formation , Brooke R. Nemec

A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus , Shrushti B. Patil

The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis , Shaun C. Stevens

Screening Next-generation Fluorine-19 Probe and Preparation of Yeast-derived G Proteins for GPCR Conformation and Dynamics Study , Wenjie Zhao

Theses/Dissertations from 2020 2020

Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses , Afua Adutwumwa Akuffo

To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria , Robert S. Brzozowski

Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface , Madison C. Davis

New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity , Dante Francis DeAscanis

Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans , Andrew Deonarine

New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability , Angelo Vincenzo de Vivo Diaz

Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches , Emily Dilandro

Succession in native groundwater microbial communities in response to effluent wastewater , Chelsea M. Dinon

Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells , Brittany A. Dudley

Allosteric Control of Proteins: New Methods and Mechanisms , Nalvi Duro

Microbial Community Structures in Three Bahamian Blue Holes , Meghan J. Gordon

A Novel Intramolecular Interaction in P53 , Fan He

The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy , Pasquale Patrick Innamarato

Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment , Wendy Michelle Kandell

Posttranslational Modification and Protein Disorder Regulate Protein-Protein Interactions and DNA Binding Specificity of p53 , Robin Levy

Mechanistic and Translational Studies on Skeletal Malignancies , Jeremy McGuire

Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression , Christina J. Moss

Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2 , Anthony Richard Sanchez IV

The Ecology and Conservation of an Urban Karst Subterranean Estuary , Robert J. Scharping

Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application , Arielle E. Tawfik

Evaluation of Aging and Genetic Mutation Variants on Tauopathy , Amber M. Tetlow

Theses/Dissertations from 2019 2019

Investigating the Proteinaceous Regulome of the Acinetobacter baumannii , Leila G. Casella

Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B , Jasmin M. D'Andrea

Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy , Nicholas T. Gimbrone

The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus , Brittney D. Gimza

Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation , Jennifer Guergues Guergues

Understanding immunometabolic and suppressive factors that impact cancer development , Rebecca Swearingen Hesterberg

Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality , Robert T. Madden

Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia , Kamira K. Maharaj

Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers , Stephanie Rockfield

Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis , Shonagh Russell

Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids , Matthew W. Saunders

Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability , Vivek M. Shastri

Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a , Oluwakemi Sowemimo

A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy , Mengyu Xie

Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks , Bi Zhao

Theses/Dissertations from 2018 2018

Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival , Lou-Ella M.m. Alexander

Identification of Regulatory miRNAs Associated with Ethanol-Induced Microglial Activation Using Integrated Proteomic and Transcriptomic Approaches , Brandi Jo Cook

Molecular Phylogenetics of Floridian Boletes , Arian Farid

MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus , Anxhela Gjyshi Gustafson

Quantitative Proteomics to Support Translational Cancer Research , Melissa Hoffman

A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer , Natalia Junqueira Sumi

Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion , Tyler S. Keeley

Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage , Katrina E. Kelly

Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics , Crystina Leah Kriss

Off-Target Based Drug Repurposing Using Systems Pharmacology , Brent M. Kuenzi

Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer , Catherine B. MarElia

The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury , Daniel Richard Martin

Theses/Dissertations from 2017 2017

Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype , Ashley Basiorka

Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning , Mohsen Botlani-Esfahani

Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans , Jessica Brunquell

The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability. , Lillian Campos-Doerfler

Mechanisms of IKBKE Activation in Cancer , Sridevi Challa

Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens , Renee Fleeman

Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer , Jeremy S. Frieling

Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein , Anusha Poosapati

Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity , Chase David Powell

Cell Division Regulation in Staphylococcus aureus , Catherine M. Spanoudis

A Novel Approach to the Discovery of Natural Products From Actinobacteria , Rahmy Tawfik

Non-classical regulators in Staphylococcus aureus , Andy Weiss

Theses/Dissertations from 2016 2016

In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices , Marvin Abountiolas

Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes , Mark Gabriel Athanason

CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment , Victoria Bryant

Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein , Priyanka Dutta

Cell Cycle Arrest by TGFß1 is Dependent on the Inhibition of CMG Helicase Assembly and Activation , Brook Samuel Nepon-Sixt

Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models , Trillitye Paullin

VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention , Waise Quarni

Regulation of nAChRs and Stemness by Nicotine and E-cigarettes in NSCLC , Courtney Schaal

Targeting Histone Deacetylases in Melanoma and T-cells to Improve Cancer Immunotherapy , Andressa Sodre De Castro Laino

Nonreplicative DNA Helicases Involved in Maintaining Genome Stability , Salahuddin Syed

Theses/Dissertations from 2015 2015

Functional Analysis of the Ovarian Cancer Susceptibility Locus at 9p22.2 Reveals a Transcription Regulatory Network Mediated by BNC2 in Ovarian Cells , Melissa Buckley

Exploring the Pathogenic and Drug Resistance Mechanisms of Staphylococcus aureus , Whittney Burda

Regulation and Targeting of the FANCD2 Activation in DNA Repair , Valentina Celeste Caceres

Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration , Dale Chaput

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Home > Life Sciences > Microbiology and Molecular Biology > Theses and Dissertations

Microbiology and Molecular Biology Theses and Dissertations

Theses/dissertations from 2024 2024.

Characterization of Cellular Metabolism Regulation by the Transcription Factor Centromere Binding Factor 1 (Cbf1) , Spencer Ellsworth

Theses/Dissertations from 2023 2023

Elucidating the Architecture of the TclIJN Complex that Converts Cysteine to Thiazoles in the Biosynthesis of Micrococcin , Diana G. Calvopina Chavez

Manipulating and Assaying Chromatin Architecture Around Enhancer Elements in vivo , John Lawrence Carter

Halophilic Genes that Impact Plant Growth in Saline Soils , Mckay A. Meinzer

Characterizing Stress Granule Regulation by PAS Kinase, Ataxin-2 and Ptc6 and Investigating the Lifespan of Covid-19 Virus on Currency , Colleen R. Newey

Changes in RNA Expression of HuT78 Cells Resulting From the HIV-1 Viral Protein R R77Q Mutation , Joshua S. Ramsey

Theses/Dissertations from 2022 2022

Biofilm Characterization and the Potential Role of eDNA in Horizontal Gene Transfer in Hospital and Meat Isolates of Staphylococcus aureus and Their Biofilms , Ashley Lynne Ball

Novel Patterns for Nucleosome Positioning: From in vitro to in vivo , David Andrew Bates

The Effects of Polymorphisms of Viral Protein R of HIV-1 on the Induction of Apoptosis in Primary Cells and the Characterization of Twelve Novel Bacillus anthracis Bacteriophage , Jacob D. Fairholm

Analysis of the Cytopathogenic Effect of Different HIV-1 Vpr Isoforms on Primary Human CD4+ T Cells and a Model Cell Line , Jonatan Josue Fierro Nieves

The Role of Chitinase A in Mastitis-Associated Escherichia coli Pathogenesis , Weston D. Hutchison

Big Data Meta-Analyses of Transcriptional Responses of Human Samples to Orthohantavirus Infection and Shotgun Metagenomics From Crohn's Disease Patients. , John L. Krapohl

An Exploration of Factors that Impact Uptake of Human Papillomavirus Vaccines , David Samuel Redd

Genomic Analysis and Therapeutic Development of Bacteriophages to Treat Bacterial Infections and Parasitic Infestations , Daniel W. Thompson

The Use of Nucleotide Salvage Pathway Enzymes as Suitable Tumor Targets for Antibody-Based and Adoptive Cell Therapies , Edwin J. Velazquez

Comparative Sequence Analysis Elucidates the Evolutionary Patterns of Yersinia pestis in New Mexico over Thirty-Two Years , M. Elizabeth Warren

Regulation of T Cell Activation by the CD5 Co-Receptor and Altered Peptides, Characterization of Thymidine Kinase-Specific Antibodies, and Integrating Genomics Education in Society , Kiara Vaden Whitley

Theses/Dissertations from 2021 2021

Evolution and Selection: From Suppression of Metabolic Deficiencies to Bacteriophage Host Range and Resistance , Daniel Kurt Arens

Identifying Sinorhizobium meliloti Genes that Determine Fitness Outcomes , Alexander B. Benedict

Pushing the Limits of SARS-CoV-2 Survival: How SARS-CoV-2 Responds to Quaternary Ammonium Compounds and Wastewater , Benjamin Hawthorne Ogilvie

Mutations in HIV-1 Vpr Affect Pathogenesis in T-Lymphocytes and Novel Strategies to Contain the Current COVID-19 Pandemic , Antonio Solis Leal

Theses/Dissertations from 2020 2020

Staphylococcus aureus Metal Acquisition in Milk and Mammary Gland Tissue , Shalee Killpack Carlson

Antimicrobial Peptide Development: From Massively Parallel Peptide Sequencing to Bioinformatic Motif Identification , Alexander K. Erikson

A Comparison of Chikungunya Virus Infection, Dissemination, and Cytokine Induction in Human and Murine Macrophages and Characterization of RAG2-/-γc-/- Mice as an Animal Model to Study Neurotropic Chikungunya Disease , Israel Guerrero

The Effects of Immune Regulation and Dysregulation: Helper T Cell Receptor Affinity, Systemic Lupus Erythematosus and Cancer Risk, and Vaccine Hesitancy , Deborah K. Johnson

Identification of Genes that Determine Fitness, Virulence, and Disease Outcomes in Mastitis Associated Eschericia coli , Michael Andrew Olson

Theses/Dissertations from 2019 2019

Investigation of Thymidine Kinase 1 in Cancer Progression , Eliza Esther King Bitter

Ribosomally Synthesized and Post-Translationally Modified Peptides as Potential Scaffolds for Peptide Engineering , Devan Bursey

Bioaerosols Associated with Evaporative Cooler Use in Low-Income Homes in Semi-Arid Climates , Ashlin Elaine Cowger

PAS Kinase and TOR, Controllers of Cell Growth and Proliferation , Brooke Jasmyn Cozzens

Regulation of Immune Cell Activation and Functionby the nBMPp2 Protein andthe CD5 Co-Receptor , Claudia Mercedes Freitas

Characterizing Novel Pathways for Regulation and Function of Ataxin-2 , Elise Spencer Melhado

Interactions Between the Organellar Pol1A, Pol1B, and Twinkle DNA Replication Proteins and Their Role in Plant Organelle DNA Replication , Stewart Anthony Morley

SNFing Glucose to PASs Mitochondrial Dysfunction: The Role of Two Sensory Protein Kinases in Metabolic Diseases , Kai Li Ong

Characterizing the Function of PAS kinase in Cellular Metabolism and Neurodegenerative Disease , Jenny Adele Pape

Isolation, Characterization, and Genomic Comparison of Bacteriophages of Enterobacteriales Order , Ruchira Sharma

Isolation, Genetic Characterization and Clinical Application of Bacteriophages of Pathogenic Bacterial Species , Trever Leon Thurgood

Investigation of Therapeutic Immune Cell Metabolism , Josephine Anna Tueller

Theses/Dissertations from 2018 2018

Innate Immune Cell Phenotypes Are Dictated by Distinct Epigenetic Reprogramming , Kevin Douglas Adams

Bacteriophages for Treating American Foulbrood and the Neutralization of Paenibacillus larvae Spores , Thomas Scott Brady

Methods for Detection of and Therapy for Carbapenem-Resistant Enterobacteriaceae , Olivia Tateoka Brown

The Diversity Found Among Carbapenem-Resistant Bacteria , Galen Edward Card

Exploration of Antimicrobial Activity in Natural Peptides and High-Throughput Discovery of Synthetic Peptides , Emma Kay Dallon

Gut Microbiota Regulates the Interplay Between Diet and Genetics to Influence Insulin Resistance , Jeralyn Jones Franson

The Antimicrobial Properties of Honey and Their Effect on Pathogenic Bacteria , Shreena Himanshu Mody

The Ability of Novel Phage to Infect Virulent Bacillus anthracis Isolates , Hyrum Smith Shumway

Galleria Mellonella as an Alternate Infection Model for Burkholderia Species and a Comparison of Suspension and Surface Test Methods for Evaluating Sporicidal Efficacy , Joseph D. Thiriot

The Clinical Significance of HPRT as a Diagnostic and Therapeutic Biomarker for Hematological and Solid Malignancies , Michelle Hannah Townsend

Biomarker Analysis and Clinical Relevance of Thymidine Kinase 1 in Solid and Hematological Malignancies , Evita Giraldez Weagel

Hospital and meat associated Staphylococcus aureus and Their Biofilm Characteristics , Trevor Michael Wienclaw

Theses/Dissertations from 2017 2017

Comparison of Cytokine Expression and Bacterial Growth During Periparturient and Mid Lactation Mastitis in a Mouse Model , Rhonda Nicole Chronis

Influence of Epstein-Barr Virus on Systemic Lupus Erythematosus Disease Development and the Role of Depression on Disease Progression , Caleb Cornaby

The Effects of Nucleosome Positioning and Chromatin Architecture on Transgene Expression , Colton E. Kempton

Phosphate Signaling Through Alternate Conformations of the PstSCAB Phosphate Transporter , Ramesh Krishna Vuppada

Acetobacter fabarum Genes Influencing Drosophila melanogaster Phenotypes , Kylie MaKay White

Theses/Dissertations from 2016 2016

The Path to Understanding Salt Tolerance: Global Profiling of Genes Using Transcriptomics of the Halophyte Suaeda fruticosa , Joann Diray Arce

Genetic and Biochemical Analysis of the Micrococcin Biosynthetic Pathway , Philip Ross Bennallack

Characterizing Interaction Between PASK and PBP1/ ATXN2 to Regulate Cell Growth and Proliferation , Nidhi Rajan Choksi

The Activity of Alkaline Glutaraldehyde Against Bacterial Endospores and Select Non-Enveloped Viruses , Justen Thalmus Despain

The Role of Viral Interleukin-6 in Tumor Development of Kaposi's Sarcoma-Associated Herpesvirus Lymphomas , Rebecca A. Fullwood

The Role of the Transcriptional Antiterminator RfaH in Lipopolysaccharide Synthesis, Resistance to Antimicrobial Peptides, and Virulence of Yersinia pseudotuberculosis and Yersinia pestis , Jared Michael Hoffman

A CryAB Interactome Reveals Clientele Specificity and Dysfunction of Mutants Associated with Human Disease , Whitney Katherine Hoopes

The pmrHFIJKLM Operon in Yersinia pseudotuberculosis Enhances Resistance to CCL28 and Promotes Phagocytic Engulfment by Neutrophils , Lauren Elizabeth Johnson

Characterization of Five Brevibacillus Bacteriophages and Their Genomes , Michael Allen Sheflo

Analysis of Nucleosome Isolation and Recovery: From In Silico Invitrosomes to In Vivo Nucleosomes , Collin Brendan Skousen

Human Herpesvirus 6A Infection and Immunopathogenesis in Humanized Rag2 -/-γc-/- Mice and Relevance to HIV/AIDS and Autoimmunity , Anne Tanner

Theses/Dissertations from 2015 2015

Identifying and Characterizing Yeast PAS Kinase 1 Substrates Reveals Regulation of Mitochondrial and Cell Growth Pathways , Desiree DeMille

The Detection and Molecular Evolution of Francisella tularensis Subspecies , Mark K. Gunnell

Isolation and Host Range of Staphylococcus aureus Bacteriophages and Use for Decontamination of Fomites , Kyle C. Jensen

The Antioxidant and DNA Repair Capacities of Resveratrol, Piceatannol, and Pterostilbene , Justin Ryan Livingston

High Salinity Stabilizes Bacterial Community Composition and Activity Through Time , Tylan Wayne Magnusson

Advancing Phage Genomics and Honeybee Health Through Discovery and Characterization of Paenibacillaceae Bacteriophages , Bryan Douglas Merrill

Specialized Replication Operons Control Rhizobial Plasmid Copy Number in Developing Symbiotic Cells , Clarice Lorraine Perry

Gene Networks Involved in Competitive Root Colonization and Nodulation in the Sinorhizobium meliloti-Medicago truncatula Symbiosis , Ryan D. VanYperen

Theses/Dissertations from 2014 2014

Snf1 Mediated Phosphorylation and Activation of PAS Kinase , Bryan D. Badal

Studies of PhoU in Escherichia coli: Metal Binding, Dimerization,Protein/Protein Interactions, and a Signaling Complex Model , Stewart G. Gardner

Pharmacologic Immunomodulation of Macrophage Activation by Caffeine , Ryan Perry Steck

Analysis of Nucleosome Mobility, Fragility, and Recovery: From Embryonic Stem Cells to Invitrosomes , Ashley Nicolle Wright

Enhancing Protein and Enzyme Stability Through Rationally Engineered Site-Specific Immobilization Utilizing Non-Canonical Amino Acids , Jeffrey Chun Wu

Theses/Dissertations from 2013 2013

Thymidine Kinase 1: Diagnostic and Prognostic Significance in Malignancy , Melissa Marie Alegre

Promoter Polymorphisms in Interferon Regulatory Factor 5 , Daniel N. Clark

Modulators of Symbiotic Outcome in Sinorhizobium meliloti , Matthew B. Crook

Evidences for Protein-Protein Interactions Between PstB and PhoU in the Phosphate Signaling Complex of Escherichia coli , Kristine Dawn Johns

Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins , Kelsey Murphey Langston

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Burkholderia pseudomallei Complex: B. mallei , B. pseudomallei , and B. thailandensis , Chinn-woan Lowe

The Role of Nuclear BMP2 in the Cell Cycle and Tumorigenesis , Brandt Alan Nichols

Nuclear BMP2 and the Immune Response , Daniel S. Olsen

Hypersaline Lake Environments Exhibit Reduced Microbial Dormancy , Joshua Christopher Vert

Theses/Dissertations from 2012 2012

Characterization of the Cellular and Organellar Dynamics that Occur with a Partial Depletion of Mitochondrial DNA when Arabidopsis Organellar DNA Polymerase IB is Mutated , John D. Cupp

Effect of Antioxidants and Oxidative Stress on Different Cancer Cell Types , Gaytri Devi Gupta Elera

Effects of Chemical Stimulation and Tumor Co-Incubation on Macrophage Activation and Aggressiveness, Measured Through Phagocytosis and Respiratory Burst , Bo Marcus Gustafsson

Loss of the Lipopolysaccharide Core Biosynthesis rfaD Gene Increases Antimicrobial Chemokine Binding and Bacterial Susceptibility to CCL28 and Polymyxin: A Model for Understanding the Interface of Antimicrobial Chemokines and Bacterial Host Defense Avoidance Mechanisms , Cynthia S. Lew

Partial Characterization of the Antimicrobial Activity of CCL28 , Bin Liu

Characterizing the Role of HspB2 in Cardiac Metabolism and Muscle Structure Using Yeast and Mammalian Systems , Jonathan Paul Neubert

Humanized Mice as a Model to Study Human Viral Pathogenesis and Novel Antiviral Drugs , Freddy Mauricio Sanchez Tumbaco

Transgene Delivery via Microelectromechanical Systems , Aubrey Marie Mueller Wilson

Theses/Dissertations from 2011 2011

Antioxidants in Cancer Research and Prevention: Assay Comparison, Structure-Function Analysis, and Food Product Analysis , Andrew Robert Garrett

Characterization of the Role Nuclear Bmp2 (nBmp2) Plays in Regulating Gene Expression , Fialka Grigorova

Theses/Dissertations from 2010 2010

Effects of Diabetic State and Gender on Pro-Inflammatory Cytokine Secretion by Human Macrophages Infected with Burkholderia pseudomallei , Annette J. Blam

Organellar DNA Polymerases Gamma I and II in Arabidopsis thaliana , Jeffrey M. Brammer

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Graduate Research Topics

Discovery, biosynthesis, and chemical ecology of microbial natural products; bioactivity and mode of action of antibiotics; biocatalyst development

Joseph A. Krzycki Biochemistry and molecular biology of methanogenic Archaea emphasizing methane formation and their genetic encoding of the novel amino acid pyrrolysine.

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Six Key Topics in Microbiology: 2024

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Theses and Dissertations (Medical Microbiology)

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• Antimicrobial, synergistic and autophagic effects of medicines for Malaria venture pathogen box compounds on resistant strains of Mycobacterium tuberculosis and Neisseria gonorrhoeae  Mensah, Eric ( University of Pretoria , 2023 ) Antimicrobial resistance in Mycobacterium tuberculosis and Neisseria gonorrhoeae is emerging globally. Due to the limited treatment options, the World Health Organization has designated M. tuberculosis and N. gonorrhoeae ...
• Genotypic profiles of emerging multidrug-resistant Staphylococcus capitis isolates from an ongoing outbreak in critically ill patients  Mynhardt, Barend J. ( University of Pretoria , 2023 ) An increasing number of linezolid resistant (LZR), multidrug-resistant (MDR) Staphylococcus capitis infections have been observed in private hospitals in the greater Gauteng area since 2014. The aim of this study was to ...
• Molecular characterisation of β-lactamase producing Klebsiella pneumoniae isolates  De Jesus, Marissa Batista ( University of Pretoria , 2015 ) Genetic typing of Klebsiella pneumoniae is used for epidemiological referencing. In the clinical setting it can be useful in outbreak investigations, understanding transmission and managing hospital infections. Multi-drug ...
• Molecular epidemiology and mechanisms of colistin and carbapenem resistance in Enterobacteriaceae from clinical isolates, the environment and porcine samples in Pretoria, South Africa  Bogoshi, Dineo ( University of Pretoria , 2020 ) Introduction: Carbapenems and colistin are the last-line antibiotics for treating Gram-negative bacterial infections. However, increasing reports of resistance to these antibiotics is being reported in clinical settings, ...
• Phenotypic and genotypic characterization of isoniazid resistance mutations in Mycobacterium tuberculosis isolates from new and previously treated patients in the Tshwane region  Sinthumule, Ndivhudzannyi Peace ( University of Pretoria , 2020 ) Background: Isoniazid (INH) is one of the most potent anti-tuberculosis (TB) drugs and a key component of the multi-drug regimen for the treatment of TB. Tuberculosis cases with initial INH resistance are more at risk ...
• Evaluation of single nucleotide polymorphisms in virulence genes of Mycobacterium tuberculosis as markers of lineages and sub-lineages in Tshwane region  Matodzi, Unarine ( University of Pretoria , 2020 ) Tuberculosis (TB) is one of the top ten leading causes of death worldwide with millions of new TB cases reported every year. Understanding the genetic diversity of Mycobacterium tuberculosis (M. tuberculosis) is very ...
• Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis  Sibandze, Busizwe Busizwe ( University of Pretoria , 2019 ) future, more robust or higher-resolution genomic typing tools, such as target Next Generation Sequencing (t-NGS) or metagenomic analysis are recommended to improve our understanding of the complexity of infections and for ...
• The association between genital mycoplasmas and bacterial vaginosis in pregnant women with or without genital symptoms  Redelinghuys, Mathys J. ( University of Pretoria , 2014 ) Bacterial vaginosis (BV) and genital mycoplasmas are infections of the reproductive tract that play important roles in maternal and foetal health. Genital mycoplasmas include Mycoplasma genitalium, M. hominis, Ureaplasma ...
• Genetic diversity of methicillin resistant Staphylococcus aureus strains in the Pretoria region in South Africa  Salawu, Adeola Mujidat ( University of Pretoria , 2014 ) Staphylococcus aureus (S. aureus) is one of the leading causes of human diseases in hospital and community settings. Methicillin resistant Staphylococcus aureus (MRSA) has emerged as a significant problem worldwide, resisting ...
• Trichomonas vaginalis and bacterial co-infections identified in reproductive age women  Sethowa, Jonas Tshoene ( University of Pretoria , 2017 ) Sexually transmitted infections (STIs) continue to be a significant public health problem with an increased burden on women of reproductive age. These infections can be transmitted between humans by means of sexual ...
• Evaluation of Mycobacterium tuberculosis clinical isolates with discordant rifampicin genotypic and phenotypic susceptibility testing results from Pretoria South Africa  Marubini, Elelwani Elliot ( University of Pretoria , 2016 ) Background. In recent years, there has been an alarming increase in cases of multidrug-resistant tuberculosis (MDR-TB), and also extensively drug-resistant tuberculosis (XDR-TB). The emergence of these forms of tuberculosis ...
• Association of Mycobacterium tuberculosis genotypes and treatment outcome in pulmonary tuberculosis patients in Tshwane Metropolitan area  Matukane, Siphiwe Ruthy ( University of Pretoria , 2015 ) Tuberculosis (TB) is a major cause of death worldwide, especially in Asia and Africa. Genotyping methods such as insertion sequence 6110-restriction fragment length polymorphism (IS6110-RFLP), spoligotyping and mycobacterial ...
• The antimicrobial effect of colistin methanesulfonate (polymyxin E) on Mycobacterium tuberculosis in vitro  Van Breda, Shane Vontelin ( University of Pretoria , 2016 ) Polymyxins have previously been described to have activity against M. tuberculosis (M. tb), but further research was abandoned due to systemic toxicity concerns to achieve the required MIC. Colistin methanesulfonate (CMS), ...
• Innovative approaches to tuberculosis diagnosis with emphasis on nucleic acid amplification tests in a resource constrained high burden tuberculosis setting  Omar, Shaheed Vally ( University of Pretoria , 2015 ) The global control of tuberculosis (TB) is currently hindered by the low sensitivity of microscopy and the prolonged time-to-result of culture. Recent technical progress has improved both diagnostic accuracy and turnaround, ...
• Phenotypic and genotypic susceptibility testing of Mycobacterium tuberculosis cultures from Tshwane Metropolitan area  Atanda, Oluwasegun Olayinka ( University of Pretoria , 2015 )
• Characterisation and detection of Mycobacterium tuberculosis in pleural biopsies using Proteomics and Molecular techniques  Mohlabeng, Mokgadi Ruth ( University of Pretoria , 2014 ) Tuberculosis (TB) remains a major global health problem. In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease (including 320 000 deaths among HIV-positive people). All countries are ...
• Phenotypic and molecular antifungal susceptibility testing of yeast isolates from Pretoria  Hnaya, Maren ( University of Pretoria , 2013 ) Antifungal drug resistance is a growing problem. Several mechanisms contribute to the development of resistance to antifungal agents. In South Africa, little is known about the antifungal susceptibility of local yeast ...
• Genetic relatedness of Mycobacterium tuberculosis strains obtained from Kalafong Hospital in Pretoria using Spoligotyping and MIRU-VNTR typing  Bulane, Atang ( University of Pretoria , 2012-12-14 ) Every year close to 9 million people contract tuberculosis (TB) and approximately 2 million die from the disease. The highest number of TB cases is in Asia while Africa has the highest incidence rates due to high rates ...
• Ausceptibility testing and resistance mechanisms to second-line agents against Mycobacterium tuberculosis in Pretoria, South Africa  Said, H.M. (Halima Mohammed) ( University of Pretoria , 2012-10-01 ) Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) is a serious problem in South Africa. Standardised and accurate drug susceptibility testing for first-line and second-line anti-TB drugs are ...
• Detection and characterization of ESBL positive Klebsiella pneumoniae clinical isolates  Manenzhe, Gumanzi Isaac ( University of Pretoria , 2012-08-14 ) Klebsiella pneumoniae is an important nosocomial pathogen that has the potential to cause severe morbidity and mortality, particularly in intensive care units, as well as in medical and surgical wards. In recent years, ...

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MSc (by Dissertation) Microbiology

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Research in our School of Life Sciences covers a wide spectrum of biology from genes to ecosystems, and this broad-based structure provides opportunities for developing novel ideas and inter-disciplinary projects. We offer supervision in a wide range of topics in microbiology, ranging from medical microbiology to environmental microbiology and from biochemical and genomic analysis of single species to whole communities.

As a research student at Essex, you'll work at the heart of our internationally acknowledged and well-connected research community. We offer world-class supervision and training opportunities, and encourage you to engage with other researchers, professionals, practitioners and research users, where possible for example using the generous funding from Proficio to attend conferences and training courses.

An MPhil and PhD are also available. Both full- and part-time study can be supported, and you can start this course in either January, April or October.

• Collaborate alongside our research groups working on important international and national problems using cutting-edge techniques.
• You will be part of our collaborative Research Groups that work on important international and national problems using cutting-edge techniques, and who have strong links with a range of organisations such as the NHS, Public Health England, the Environment Agency, Cefas, Defra, oil companies and Anglian Water.
• The quality of our work is reflected in the large number of publications in high-profile academic journals our staff feature in.

Our expert staff

Within our School of Life Sciences, you will be allocated a supervisor whose role it is to guide you through the different stages of your research degree. In some cases, you may be jointly supervised.

The support provided by your supervisor is a key feature of your research student experience and you will have regular one-to-one meetings to discuss progress on your research. Initially, your supervisor will help you develop your research topic and plan.

Twice a year, you will have a supervisory board meeting, which provides a more formal opportunity to discuss your progress and agree your plans for the next six months.

Your technical and intellectual development will be enhanced by becoming part of a Research Group, and participating in School Seminars.

Specialist facilities

Our School of Life Sciences provides a comprehensive range of facilities for medical and environmental microbiology research which include fully automated laboratories with robotic liquid-handling systems and facilities for microbial culture, cell culture, molecular biology, gene editing and next-generation sequence analysis and an advanced bioimaging suite to visualise and process analyse images of biological processes in real time.

A dedicated study room allows all our postgraduate research students to have access to a desk and a computer outside of the research laboratories. This provides a focal point for our postgraduates, facilitating reading and writing as well as good communication and a sense of community.

Your future

Many of our postgraduates continue their scientific research by taking up postdoctoral positions in the UK and overseas. Others have embarked on careers in biomedical laboratories and in the pharmaceutical and biotechnology industries, or governmental and non-governmental organisations. We support your career development by a mentoring scheme and employability events.

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Home » Blog » Dissertation » Topics » Microbiology » 80 Microbiology Research Topics

80 Microbiology Research Topics

FacebookXEmailWhatsAppRedditPinterestLinkedInResearch is the cornerstone of academic pursuit, and for students in the realm of microbiology, the choice of research topics can be the pivotal axis on which their thesis or dissertation pivots. Microbiology encompasses many issues, each offering a unique lens to scrutinize the unseen world of microorganisms. From investigating microbial ecology to probing the […]

Research is the cornerstone of academic pursuit, and for students in the realm of microbiology, the choice of research topics can be the pivotal axis on which their thesis or dissertation pivots. Microbiology encompasses many issues, each offering a unique lens to scrutinize the unseen world of microorganisms. From investigating microbial ecology to probing the intricacies of molecular virology, the breadth of research topics available is expansive. Crafting a research topic that aligns with your interests, leverages your skills, and contributes to the field is a critical step toward a successful research journey at the undergraduate, master’s, or doctoral level.

Microbiology, the study of microscopic organisms such as bacteria, viruses, fungi, and protozoa, delves into understanding their structure, behavior, physiology, and interactions with their environments. Also referred to as microbial biology, this discipline is an amalgamation of various sciences, including biology, genetics, biochemistry, and immunology, providing a comprehensive understanding of the unseen, minute organisms that play significant roles in different natural and artificial settings.

A List Of Potential Research Topics In Microbiology:

• Investigating the microbial communities in the human respiratory tract and their role in infections.
• Analyzing the role of gut microbiota in COVID-19 susceptibility and severity.
• Investigating the role of the human microbiome in metabolic disorders among the UK population.
• Studying the microbial ecology of built environments and its implications for human health.
• Elucidating the mechanisms of antimicrobial resistance in emerging opportunistic pathogens.
• Exploring the use of CRISPR-Cas technology for targeted manipulation of microbial genomes.
• Investigating the microbial ecology of wastewater treatment systems and bioremediation approaches.
• Evaluating the impact of microbial biofilms on medical device-associated infections and prevention strategies.
• Characterizing the immune response and microbiota interactions in COVID-19 patients.
• Assessing the role of the skin microbiome in wound healing and tissue regeneration.
• Analyzing the microbiological implications of long COVID syndrome.
• Studying the impact of COVID-19 on antibiotic resistance and antimicrobial stewardship.
• Understanding the interactions between soil microbes and plant pathogens for sustainable agriculture.
• Assessing the antimicrobial properties of natural compounds against multidrug-resistant bacteria.
• Exploring the role of the microbiome in mental health disorders and potential therapeutic interventions.
• Antibiotic alternatives: exploring the potential of bacteriophages in the era of antibiotic resistance.
• Understanding the prevalence and characteristics of healthcare-associated infections in UK healthcare facilities.
• Exploring the impact of climate change on the distribution and behavior of microbial communities in UK water bodies.
• Understanding the role of the skin microbiome in dermatological conditions and therapies.
• The interplay of microbial life in atmospheric ecosystems: exploring microbiology’s connection to meteorological processes.
• Evaluating the potential of phage therapy as an alternative to antibiotics in treating bacterial infections.
• Evaluating the influence of host genetics on the vaginal microbiome and associated health outcomes.
• Investigating microbial communities in the built environment and their link to respiratory health issues.
• Studying microbial interactions in the context of chronic wounds and implications for wound care.
• Assessing the potential of engineered microbial consortia for environmental remediation.
• Analyzing the microbial profiles of fermented foods and their potential health benefits.
• Studying the microbial basis of food spoilage and strategies to enhance food preservation.
• Analyzing the microbial composition of traditional UK fermented foods and their health implications.
• Assessing the impact of climate change on microbial community dynamics in Arctic ecosystems.
• Studying the role of microorganisms in the degradation of plastic waste and environmental sustainability.
• A comprehensive review of the gut-brain axis: microbiota communication and its implications for neurological disorders.
• Investigating the impact of microbial biofilms on dental health and hygiene practices.
• Analyzing the impact of microbial symbiosis on plant growth and agricultural sustainability.
• Evaluating the impact of microbial metabolites on host physiology and disease susceptibility.
• The role of the skin microbiome in dermatological conditions: a comprehensive review.
• Investigating antiviral properties of natural compounds against COVID-19.
• Assessing the potential of microbiome-based therapeutics for inflammatory bowel diseases.
• Exploring the potential of synthetic biology in redesigning microbial metabolism: a critical review.
• Understanding the role of the lung microbiome in respiratory diseases and infections.
• Investigating the influence of the vaginal microbiota on reproductive health and fertility outcomes.
• Exploring the impact of pollution on the microbial communities in UK urban environments.
• Evaluating the impact of antibiotics in early life on the development of the infant gut microbiome.
• Understanding the role of the lung microbiome in chronic respiratory diseases and exacerbations.
• Analyzing the microbial ecology of historic sites and its preservation in the UK.
• Exploring the microbiota-gut-brain axis in autism spectrum disorder and potential interventions.
• Investigating the microbial diversity in UK agricultural soils and its role in sustainability.
• Evaluating the persistence and transmission of SARS-CoV-2 in various environmental reservoirs.
• Assessing the microbial diversity and composition in extreme environments: implications for astrobiology.
• Investigating the microbiological safety of food and water during and after the COVID-19 pandemic.
• Analyzing the impact of microbial interactions on antibiotic production and efficacy.
• Investigating the microbial diversity and functions in deep-sea ecosystems and extremophiles.
• Microbiota modulation for improved cancer immunotherapy outcomes: a systematic review.
• Understanding the role of viruses in shaping microbial communities and ecological dynamics.
• Investigating microbial adaptations to extreme environments and their potential biotechnological applications.
• Analyzing the role of microbiota in the development and progression of autoimmune skin disorders.
• Exploring the potential of bacteriophages as therapeutic agents against COVID-19.
• Antimicrobial resistance and drug development: a symbiotic study of microbiology and pharmacology for future therapeutic strategies.
• Investigating the microbial basis of cystic fibrosis and its implications for therapeutic strategies.
• Microbiome-host interactions in inflammatory bowel disease: a systematic review of current research.
• Investigating microbial interactions in the human oral cavity and their effects on oral health.
• Studying the microbial ecology of hydrocarbon-contaminated sites and bioremediation strategies.
• Analyzing the role of gut microbiota in modulating immune responses and autoimmune disorders.
• Analyzing the gut-brain axis and its influence on mental health, cognition, and behavior.
• Assessing the microbial contributions to odontogenic infections and oral health.
• The role of the oral microbiome in systemic diseases: a comprehensive review.
• Exploring the gut-brain axis: microbial influences on neurodegenerative diseases and mental health.
• Evaluating the use of microbial enzymes in industrial processes for enhanced efficiency and sustainability.
• Assessing the antibiotic resistance profile of common pathogens in UK hospitals.
• Understanding the role of the oral microbiome in systemic diseases and overall health.
• Assessing the potential of microbiome-based interventions in mitigating allergic diseases.
• Exploring the role of microbial communities in the degradation of environmental pollutants.
• Analyzing the role of gut microbiota in modulating drug metabolism and efficacy.
• Assessing the microbiome alterations in COVID-19 survivors and its impact on long-term health.
• Analyzing the microbial communities in aquatic environments and their response to pollutants.
• Studying the microbial contamination of recreational waters in popular UK tourist destinations.
• Evaluating the efficacy of probiotics in mitigating antibiotic-associated diarrhea in pediatric populations.
• Investigating the microbiota of the human gastrointestinal tract and its impact on metabolic disorders.
• Harnessing the power of microbial biotechnology for environmental sustainability: a systematic review.
• Assessing the role of microorganisms in bioremediation of polluted sites in the UK.
• Studying the impact of the skin microbiome on dermatological conditions and treatment outcomes.

In microbiology, research topics are as diverse as the microscopic organisms they seek to unravel. Whether you’re an undergraduate embarking on a foundational exploration or a doctoral candidate diving deep into the intricacies of microbial ecosystems, the spectrum of research topics in microbiology is expansive. From the impacts of microbiomes on human health to the biotechnological applications of microbial enzymes, each case holds the promise of contributing to our understanding of the microbial world and shaping the future of science and technology. Choose wisely, for your research journey starts with a single topic; from there, the possibilities are limitless.

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100+ microbiology research topics to succeed.

Microbiology topics are some of the most researched ideas. This field entails the study of different microorganisms, ranging from eukaryotic fungi and single-celled organisms to cell-cluster organisms. When pursuing a microbiology course in a university or college, your educators will ask you to write academic papers on microbiology research topics.

Choosing the right microbiology topics to write about is essential because it determines the direction of your research and writing processes. Therefore, take your time to identify a topic you will be comfortable working with from the beginning to the end.

Top Microbiology Topics for Research

If looking for the top microbiology research paper topics, this list has some of the best ideas to explore. That’s because most people are searching for information related to these topics in microbiology.

• Bioterrorism- Bioweapons limit with technological developments
• Antibiotics resistance- A major limitation in medicine
• Extraterrestrial life- Existing life evidence in space
• Gene therapy- Gene therapy as a controversial biology topic
• Cloning- Latest developments in cloning research
• Antibacterial products-Latest discoveries explaining the possibility of antibacterial products effects on the immune system
• What is the future of microbiology research, both theoretically and technologically?
• Epidemics- Current disease control protocols and possible solutions
• Vaccines- Recent research about the effectiveness of vaccines like flue
• Food preservation methods- How technology enhances safe food preservation and consumption

These are brilliant microbiology project topics. However, you need time and effort to research any of these topics and come up with an awesome paper.

Current Topics in Microbiology and Immunology

Maybe you want to research and write about current topics in microbiology and immunology. That means you’re looking for topics that will enable you to explore recent information in this area. In that case, consider these microbiology topics in the news.

• Virus-like particle vaccines for protozoan parasites and respiratory viruses
• Quorum sensing and campylobacter biofilm formation in molecular mechanisms
• Campylobacter horizontal gene and natural competence transfer
• Murine investigation models for innate immune response and colonization resistance in campylobacter jejuni infections
• iBALT role in respiratory immunity
• Antiviral immunity for pyroptosis
• Damage to the sensing tissue by Myeloid c-Type Lectin receptors
• How antifungal drugs modify the cell wall
• Host cell’s death pathways manipulation by the Herpes Simplex virus
• Type II Secretion system structures in needle filaments
• RIP Kinase signaling outcomes during neuro-invasive infection by virus
• Innate immune system pathological and physiological functions of CARD 9 signaling
• The genetics of the Lassa virus
• Genital immunity’s memory lymphocyte- Tissue-resident memory T cells’ role
• Delivery and formulation technologies for the mRNA vaccines
• Peptide and protein nanocluster vaccines
• Reovirus’ cell killing- Consequences and mechanisms
• Leptospirosis reference lab’s role
• Hypoxia-inducible and hypoxia factors in stem cell maintenance among cancer patients
• Development of dengue vaccine

Pick any of these new research topics in microbiology if your goal is to work on recent information. Nevertheless, take your time reading recent literature in this field to come up with an awesome paper.

Interesting Topics in Microbiology

Perhaps, you’re looking for microbiology projects topics that most people will find interesting to read about. In that case, consider these interesting microbiology topics.

• Techniques and methodologies for future research about the virus
• Redox-active metabolite’s roles in microbial signaling
• The role and emergence of yeast as a baking industry’s preservative
• Host-pathogenic interactions study with a focus on redox and cellular metals
• Yeast non-conventional use in the wine-making industry
• Microbiota- What is the bifidobacterila’s role in the human gut?
• Virus role in vaccines development and improvement in third world countries
• Heath- Microbiology role in addressing antibiotic resistance
• Human microbial ecosystems study- Microbe interactions
• Impact and role of viruses in large animals’ health
• How bacteria in complex organisms respond to stress
• Cell to cell interaction and social behavior in bacteria interactions
• Norovirus cross-contamination investigation during service procedures in the food industry in fresh produce preparation
• Transfer rate determination in Salmonella sp. From nut butter to food materials
• Listeria monacytogenes comparative genomic analysis for survival within a food processing situation
• Thermal resistance and survival of desiccated Salmonella in dry and moist food processing environments
• Effective cleaning products for removing food matrix with B. Thuringiensis spores and B. Cereus
• Analysis of cleaning procedures’ effects on Bacillus spores
• How temperature affects viruses survival in vegetables and fruits
• How temperature and time combine to stimulate C. botulinum spores to germinate or produce a toxin

This category has some of the most interesting and easy microbiology research topics. However, take your time to research the topic you choose to write a paper that will impress your educator to award you the top grade.

Medical Microbiology Research Topics

Maybe you want to explore microbiology and human health topics. In that case, consider these medical-related microbiology paper topics.

• Probiotics- A study of their preparation
• How to prevent sickle cell anemia
• The growth of mold
• How fertilizes, polythene and manure affect the hypocotyl’s elongation rate
• How cinnamon and curry inhibit the growth of bacteria
• How oil spills affect microorganisms in the oceans
• Reproducing yeast in sugar substitutes
• Why vitamin c affects the rotting rate for fruits
• Effective toothbrush disinfecting methods
• Describe the spread of Ebola

Consider any of these microbiology research topics research paper if interested in something to do with medicine. However, take your time to identify good and authentic information sources before you start writing your paper. That’s because your educator will be interested in unique and relevant content.

Microbiology Research Topics for Undergraduates

Are you pursuing undergraduate studies in microbiology? If yes, you will find these microbiology research topics for college students interesting.

• Using polymerase chain reaction to diagnose infectious diseases
• Preliminary antimicrobial and phytochemical screening of coat and seed of citrus sinensis
• Microbiology effect on mining
• Human skin colonization by bacteria
• Sweet orange’s antibacterial activity on Escherichia coli and staphylococcus aureus isolated from wound infection
• The susceptibility pattern of bacteria to antibiotics
• Bush pear analysis and the oil project
• Spoilt avocado microbial examination- What it reveals
• Characterization and isolation of microorganisms from a stored pap
• CryoEM use in understanding pathogen resistance and transport
• Additive manufacture of skin-facing antimicrobial devices for surgery
• Oral bacteria’s role in cardiovascular disease
• Nutrient-mediated ‘Dual warhead’ antimicrobials’ delivery
• Induction mechanisms of the protective lung tissue memory cells in influenza
• The activity of eukaryotic, elucidating topoisomerase in homologous recombination
• Oral bacteria involvement in chronic periodontitis- Metabolomics investigation
• Effect of metal nanoparticles on the multi-species biofilm consortia- A metabolomics investigation
• How vaping or smoking affects the risk of CoV-2, SARS, and COVID-19 outcomes
• Soil contaminants risks on below and above ground eco-systems in urban areas
• Protective microbes- How to rebuild microbiota when treating AMR infection

This category also has some of the best microbiology topics for presentation. However, get ready to research any of these topics to write an impressive paper.

Hot Topics in Microbiology

Perhaps, you’re looking for the most interesting microbiology essay topics to research and write about. In that case, consider some of the ideas in this category.

• Shea butter’s microbiological analysis
• Research of tapeworms and their dangers
• Influenza spread in the world and its impact on the war
• Restriction-modification cellular microbiology
• Applied microbiology- Biofuels generation using microorganisms
• Microscope invention and its effect on microbiology knowledge
• Microbiology role in food industries and pharmaceutical
• How microbiology has helped in preventing life-threatening illnesses
• Bacterial polymer- A study of cyanophycin
• A study of the functionalities and properties of wetland bacteria
• Microbiological study of a commercial preparation of yogurts
• A study of bacteria that withstand antibiotics
• Human immunodeficiency virus diagnosis- How it’s done
• A study of plasmodium species correlation
• A study of onions’ microorganisms
• An investigation of starch fermentation, specificities, and activities of its enzymes
• Listeria growth and survival in freshly cut vegetables
• Low moisture food inoculation protocols
• Survival and growth of Salmonella during partially sprouted products processing and chia powders
• Environmental organisms’ risk assessment and the importance of better control and knowledge

This category also has some of the best food microbiology topics. Nevertheless, students should be ready to spend time and effort researching any of these ideas before writing. That’s because educators expect them to present fresh and relevant information in their papers.

Learners have many topics or ideas to consider when researching and writing academic papers. However, every student should look for an interesting topic they are comfortable researching and writing about. That’s because writing a research paper or essay takes time. Choosing a boring topic means a learner will spend their time working on something they’re not interested in. And this can reflect on the quality of their paper. Thus, their grade will suffer.

Thesis projects for BSc and MSc students

The Laboratory of Microbiology offers graduation projects for BSc and MSc students in different research groups. Find out more below.

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[100+] Microbiology Research Topics For College Students With Free [Thesis Pdf] 2023

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List of the Best Microbiology Dissertation Topics For UK Students.

Microbiology is a really interesting subject area with lots of things to discover. And if you are wondering to make your dissertation on it, then opt for it because it will be a great show stopper. You can easily find some great topics online. There are lots of things in microbiology that you can select from and that will be easy to find a topic.

Here in this article, we discuss some topics in the dissertation for Msc microbiology which you can adopt to take help, once you start doing research, it will take no time to find the topic. In short, select the below topic and make it unique by focusing on a different demographic location.

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Unexplored Microbiology Research Topics For Postgraduate

Below are the unexplored and unique topics for dissertation in microbiology that will make you stand out among other students. Let’s explore them.

• Future viral research methodologies and approaches
• Microbial Signaling: the Roles of Redox-Active Metabolites
• The history of yeast and its use as a preservative in the baking sector.
• A study of the interactions between the host and the pathogen, with a focus on cellular and redox metals.
• The role of viruses in vaccine development and its enhancement in third-world countries.
• Analysis of quantifying bacterial adhesion to materials.
• Yeast cells’ adaptive response to phosphoribulokinase-induced toxicity
• A study on the biological function of an artificial wetland is investigated.
• Bacteria were acquired by the oral cavity community.
• Designing a spaceship environment: Bacterial biofilm evolution on various materials used in the International Space Station
• Tripartite efflux pumps in bacteria: structure and mechanism
• What we’ve learned about bacteriophage research and what we still need to know
• Evaluating the use of diversity indices to discriminate across microbial communities with various features.
• The role of pH in determining the relative toxicity of copper and chloride to acidophilic bacteria.
• Investigation into the discovery and isolation of bacteria linked to sepsis in wounds.
• Investigation of the commercially made yogurts is tested for microbial and microbiological contamination.
• Biosorbents based on peptides are potential methods for resource recovery.
• Enzyme activity and specificity in maize starch fermentation
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• Keeping it together: during predation, the predatory bacteria Micavibrio aeruginosavorus and Bedellovibrio bacteriovorus lack genetic variation and DNA incorporation.

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100+ Microbiology Project Topics [Updated]

Microbiology, the study of microorganisms, holds immense importance in the realms of medicine, agriculture, industry, and environmental science. It’s a field teeming with opportunities for exploration and discovery. For students passionate about unraveling the mysteries of the microbial world, engaging in microbiology projects is not just educational but also immensely rewarding.

In this blog, we aim to provide a comprehensive guide to over 100 updated microbiology project topics across various sub-disciplines. Whether you’re a student seeking inspiration for your next research endeavor or an educator looking to expand your list of project ideas, this resource is tailored to meet your needs.

Choosing a Microbiology Project Topic

Table of Contents

Selecting the right project topic is crucial for the success and fulfillment of your research journey. Here are some key considerations to keep in mind:

• Personal Interest and Career Goals: Opt for a topic that aligns with your interests and long-term career aspirations. Whether it’s bacterial pathogenesis, virology, immunology, environmental microbiology, food microbiology, or clinical microbiology, choose a subject that excites you.
• Relevance to Current Trends: Stay abreast of the latest advancements and trends in microbiology. Topics related to emerging infectious diseases, antibiotic resistance, microbiome research, and biotechnological applications are particularly timely and impactful.
• Resource Availability and Feasibility: Assess the availability of laboratory resources, equipment, and expertise required for your chosen project. Ensure that your topic is feasible within the constraints of your academic or research environment.

100+ Microbiology Project Topics

Now, let’s delve into our curated list of microbiology project topics across various sub-disciplines:

Bacterial Microbiology

• Role of quorum sensing in bacterial biofilm formation.
• Antibiotic resistance mechanisms in clinically relevant bacterial strains.
• Bacteriophages as alternative therapeutics for antibiotic-resistant infections.
• Molecular mechanisms of bacterial pathogenicity using model organisms.
• Genetic diversity and evolution of influenza viruses for vaccine development.
• Host-virus interactions underlying viral replication and pathogenesis.
• Metagenomic profiling of viral communities to identify novel pathogens.
• Screening natural products for antiviral activity against emerging diseases.
• Efficacy of novel vaccine formulations in eliciting immune responses.
• Immunomodulatory effects of probiotics on mucosal immunity and gut health.
• Dysregulated immune responses in autoimmune disorders.
• Host immune evasion strategies in persistent viral infections.

Environmental Microbiology

• Microbial diversity in hydrothermal vent ecosystems using next-generation sequencing.
• Biodegradation of environmental pollutants by microbial consortia.
• Extremophilic microorganisms adapted to harsh environmental conditions.
• Role of soil microbiota in plant growth promotion and biocontrol.

Food Microbiology

• Microbial contamination in food processing facilities and sanitation practices.
• Identification and characterization of foodborne pathogens.
• Spoilage mechanisms of food products and strategies for shelf life extension.
• Safety and efficacy of probiotic supplements in fermented foods.

Clinical Microbiology

• Molecular epidemiology of healthcare-associated infections using whole-genome sequencing.
• Mechanisms of antimicrobial resistance in clinically important pathogens.
• Human microbiome profiling in health and disease states using metagenomics.
• Rapid diagnostic tests for infectious diseases in clinical settings.

Miscellaneous Topics

• Microbial ecology of the human gut microbiota.
• Role of microbiota in neurodevelopmental disorders like autism.
• Microbiological aspects of bioremediation in environmental cleanup efforts.
• Microbial production of biofuels and bioplastics.
• Application of CRISPR-Cas technology in microbial genome editing.
• Microbial production of enzymes for industrial processes.
• Microbial synthesis of novel antimicrobial compounds.
• Microbial fermentation processes for food and beverage production.
• Bioinformatics analysis of microbial genomes and metagenomes.
• Microbial ecology of extreme environments, such as deep-sea hydrothermal vents.
• Microbiological aspects of the human skin microbiome and its implications for health.
• Microbial diversity and ecosystem functions in freshwater and marine environments.
• Microbial interactions in symbiotic relationships with plants and animals.
• Microbial biogeochemical cycling of elements in terrestrial and aquatic ecosystems.
• Microbial diversity and community composition in urban environments.
• Microbial ecology of infectious diseases in wildlife populations.
• Microbial contributions to nutrient cycling and soil fertility in agricultural systems.
• Microbial contamination of water sources and strategies for water quality management.
• Microbial degradation of pollutants in soil and water environments.
• Microbial diversity and biotechnological potential of hot springs and thermal vents.
• Microbial ecology of the built environment, including hospitals and households.
• Microbial interactions in the rhizosphere and their effects on plant health and productivity.
• Microbial diversity and function in extreme environments, such as polar regions and deserts.
• Microbial ecology of air quality, including indoor and outdoor microbial communities.
• Microbial contributions to biogeochemical cycling in aquatic ecosystems, such as lakes and oceans.
• Microbial roles in the decomposition of organic matter and nutrient cycling in forest ecosystems.
• Microbial diversity and community dynamics in mangrove ecosystems and their ecological functions.
• Microbial contributions to the degradation of pollutants and xenobiotics in contaminated environments.
• Microbial interactions with pollutants and their role in environmental remediation strategies.
• Microbial diversity and function in hydrothermal vent ecosystems and their biogeochemical significance.
• Microbial diversity and community composition in permafrost environments and their response to climate change.
• Microbial ecology of extremophiles and their adaptations to extreme environmental conditions.
• Microbial diversity and function in deep-sea environments, including the deep ocean and hydrothermal vents.
• Microbial contributions to the biogeochemistry of carbon, nitrogen, and sulfur cycling in marine ecosystems.
• Microbial interactions with marine organisms and their role in marine food webs and ecosystem dynamics.
• Microbial diversity and function in coral reef ecosystems and their response to environmental stressors.
• Microbial contributions to the cycling of nutrients and organic matter in coastal ecosystems and estuaries.
• Microbial diversity and community composition in Arctic and Antarctic environments and their response to climate change.
• Microbial interactions with marine pollutants and their role in the degradation and detoxification of contaminants.
• Microbial diversity and function in marine sediments and their role in biogeochemical cycling and ecosystem functioning.
• Microbial ecology of deep-sea hydrothermal vents and cold seeps and their contributions to global biogeochemical cycles.
• Microbial diversity and community dynamics in oceanic oxygen minimum zones and their implications for carbon and nitrogen cycling.
• Microbial interactions with marine organisms and their role in shaping marine biodiversity and ecosystem structure.
• Microbial contributions to the cycling of nutrients and energy in marine ecosystems, including primary production and decomposition processes.
• Microbial diversity and function in marine plankton communities and their role in biogeochemical cycling and ecosystem productivity.
• Microbial ecology of marine symbioses, including mutualistic, commensal, and parasitic relationships between microbes and marine organisms.
• Microbial interactions with marine pollutants and their role in the biodegradation and detoxification of contaminants in marine environments.
• Microbial diversity and community composition in marine sediments and their role in biogeochemical cycling, nutrient regeneration, and sediment stability.
• Microbial contributions to the cycling of nutrients and energy in coastal ecosystems, including estuaries, salt marshes, and mangrove forests.
• Microbial diversity and function in coastal sediments and their role in biogeochemical cycling, organic matter degradation, and nutrient fluxes.
• Microbial ecology of marine viruses and their role in shaping microbial communities, nutrient cycling, and ecosystem dynamics in marine environments.
• Microbial diversity and community composition in marine snow aggregates and their role in transporting carbon, nutrients, and microbes in the ocean.
• Microbial interactions with marine organisms and their role in mediating host-microbe interactions, disease dynamics, and ecosystem functioning.
• Microbial contributions to the cycling of carbon and sulfur in marine sediments, including the role of anaerobic microbial processes in sedimentary environments.
• Microbial diversity and function in marine hydrothermal vent ecosystems and their role in chemosynthetic primary production, mineral precipitation, and ecosystem sustainability.
• Microbial ecology of marine deep-sea ecosystems, including abyssal plains, trenches, and seamounts, and their role in global biogeochemical cycles and biodiversity.
• Microbial diversity and community composition in marine sponge microbiomes and their role in nutrient cycling, secondary metabolite production, and host-microbe interactions.
• Microbial interactions with marine pollutants and their role in the bioremediation of oil spills, heavy metal contamination, and other anthropogenic pollutants in marine environments.
• Microbial contributions to the cycling of nutrients and energy in deep-sea ecosystems, including the role of chemosynthetic microbes in supporting deep-sea food webs and ecosystem functioning.
• Microbial diversity and function in marine coral reef ecosystems and their role in reef health, resilience, and recovery from environmental stressors such as climate change, pollution, and disease.
• Microbial ecology of marine plastic pollution and its impact on marine ecosystems, including microbial degradation of plastic polymers, biofilm formation on microplastic surfaces, and microbial interactions with plastic-associated pollutants.
• Microbial diversity and community composition in marine coastal habitats, including rocky shores, sandy beaches, and tidal pools, and their role in coastal ecosystem processes, biodiversity, and ecosystem services.
• Microbial interactions with marine organisms and their role in mediating host-microbe interactions, disease dynamics, and ecosystem functioning in marine ecosystems, including coral reefs, kelp forests, and seagrass meadows.
• Microbial contributions to the cycling of nutrients and energy in marine ecosystems, including the role of microbial processes in carbon sequestration, nitrogen fixation, and nutrient regeneration in the oceanic food web.
• Microbial diversity and function in marine pelagic ecosystems, including the open ocean, coastal upwelling zones, and polar seas, and their role in primary production, nutrient cycling, and global climate regulation.
• Microbial ecology of marine biofilms and their role in ecosystem processes, including biofouling, biocorrosion, and nutrient cycling in marine environments, such as ship hulls, oil platforms, and marine infrastructure.
• Microbial diversity and community composition in marine benthic habitats, including deep-sea sediments, hydrothermal vents, and cold seeps, and their role in biogeochemical cycling, energy flow, and ecosystem stability.
• Microbial interactions with marine pollutants and their role in the biodegradation, detoxification, and bioaccumulation of contaminants in marine ecosystems, including oil spills, heavy metals, plastics, and agricultural runoff.
• Microbial contributions to the cycling of nutrients and energy in marine ecosystems, including the role of microbial processes in carbon fixation, nitrogen cycling, and sulfur metabolism in marine food webs and biogeochemical cycles.
• Microbial diversity and function in marine deep-sea ecosystems, including abyssal plains, trenches, and seamounts, and their role in global biogeochemical cycles, biodiversity, and ecosystem functioning.
• Microbial ecology of marine sponge microbiomes and their role in nutrient cycling, secondary metabolite production, and host-microbe interactions in marine ecosystems, including coral reefs, mangrove forests, and seagrass meadows.
• Microbial interactions with marine pollutants and their role in the bioremediation of oil spills, heavy metal contamination, and other anthropogenic pollutants in marine environments, including coastal waters, estuaries, and marine sediments.
• Microbial contributions to the cycling of nutrients and energy in deep-sea ecosystems, including the role of chemosynthetic microbes in supporting deep-sea food webs, hydrothermal vent communities, and cold seep ecosystems.
• Microbial diversity and function in marine pelagic ecosystems , including the open ocean, coastal upwelling zones, and polar seas, and their role in primary production, nutrient cycling, and global climate regulation in the marine biosphere.
• Microbial diversity and community composition in marine benthic habitats, including deep-sea sediments, hydrothermal vents, and cold seeps, and their role in biogeochemical cycling, energy flow, and ecosystem stability in the deep sea.
• Microbial interactions with marine pollutants and their role in the biodegradation, detoxification, and bioaccumulation of contaminants in marine ecosystems, including oil spills, heavy metals, plastics, and agricultural runoff in coastal and oceanic environments.

Tips for Successful Microbiology Projects

Embarking on a microbiology project can be both exhilarating and challenging. Here are some tips to help you navigate the research process with confidence:

• Planning and Organization: Start with a clear research question and outline a detailed project plan with achievable milestones.
• Literature Review: Thoroughly review existing literature to build a solid theoretical framework for your research.
• Laboratory Techniques and Safety: Adhere to best practices for experimental design, data collection, and laboratory safety protocols.
• Data Analysis and Interpretation: Utilize appropriate statistical methods and data visualization tools to analyze your results effectively.
• Effective Communication: Prepare concise and compelling presentations or manuscripts to communicate your findings to peers and stakeholders.

In conclusion, microbiology offers a vast playground for exploration and innovation. By choosing the right project topic and following sound research principles, you can make meaningful contributions to our understanding of the microbial universe.

We hope this curated list of microbiology project topics serves as a valuable resource for students and educators alike, inspiring the next generation of microbial enthusiasts to embark on their research journeys. Happy exploring!

Feel free to share your thoughts, feedback, or additional project ideas in the comments section below. Together, let’s continue unraveling the mysteries of microbiology!

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Manandmicrobes

43 Project Topics on Food Microbiology: Latest

Food microbiology is a branch of microbiology that focuses on the study of microorganisms in food. It plays a crucial role in ensuring food safety, quality, and preservation. 

Engaging in a food microbiology project provides an opportunity to delve deeper into the intricate world of microorganisms present in our food and their impact on various aspects of the food industry. 

Choosing Food Microbiology Project Topics 

Selecting an appropriate and engaging project topic is essential in food microbiology research. It involves considering current trends, challenges, and advancements in the field. 

Researching topics related to foodborne illnesses, emerging pathogens, food spoilage, or food preservation techniques can provide valuable insights and contribute to the existing body of knowledge. 

Collaborating with experts and industry professionals can also offer guidance and ensure the relevance of the chosen topic. 

Sample Food Microbiology Project Topics 

1. Analyzing the microbial contamination of food-handling surfaces

This project aims to investigate the presence and persistence of microorganisms on different food contact surfaces and evaluate the effectiveness of sanitation practices. 

2. Studying the role of microorganisms in food spoilage

This project focuses on identifying the microbial species responsible for food spoilage and understanding the factors that contribute to their growth and proliferation. 

3 Investigating the effectiveness of food preservation techniques

This project aims to assess the efficiency of various food preservation methods, such as thermal processing, freezing, drying, or fermentation, in controlling microbial growth and extending the shelf life of food products. 

4. The impact of processing methods on the microbial quality of dairy products 

5. Investigating the microbial safety of raw and processed seafood 

6. Assessing the effectiveness of natural antimicrobial compounds in food preservation 

7. Microbiological analysis of fermented foods and their health benefits 

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8. Investigating the role of microorganisms in the production of foodborne toxins 

9. Studying the microbial diversity and dynamics of artisanal cheese production 

10. Evaluating the microbial quality of fresh fruits and vegetables along the supply chain 

11. Analyzing the prevalence and antimicrobial resistance of bacteria in poultry products 

12. Exploring the microbiological quality and safety of ready-to-eat foods 

13. Investigating the role of biofilms in foodborne pathogen persistence and contamination 

14. Assessing the microbial spoilage of bakery products and the factors influencing it 

15. Studying the microbial ecology of fermented beverages (e.g., beer, wine, kombucha) 

16. Analyzing the microbiological safety of street foods in urban areas 

17. Investigating the occurrence and control of foodborne viruses in food processing environments 

18. Exploring the microbial composition of traditional fermented foods from different cultures 

19. Assessing the microbiological quality of spices and herbs used in food preparation 

20. Investigating the impact of food processing techniques on the survival of probiotic bacteria 

21. Studying the microbial safety of plant-based alternatives to meat and dairy products 

22. Analyzing the microbiological quality of processed meat products and the presence of pathogens 

23. Investigating the microbial ecology of food production facilities and the prevention of contamination

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Food microbiology seminar topics

Here’s a list of seminar topics in food microbiology:

1. Foodborne pathogens: Identification, detection, and control strategies 

2. Microbial spoilage of food: Causes, mechanisms, and prevention 

3. Emerging trends in food microbiology research 

4. Microbiological safety of fresh produce: Challenges and solutions 

5. Role of probiotics in promoting gut health and food safety 

6. Microbial ecology of fermented foods and beverages 

7. Antimicrobial resistance in foodborne bacteria: Implications and interventions 

8. Foodborne viruses: Detection, transmission, and control measures 

9. Microbial risks associated with seafood consumption 

10. Microbiological quality and safety of street foods 

11. Microorganisms in food processing environments: Monitoring and control 

12. Microbial hazards in dairy products and their control strategies 

14. Food preservation techniques: Traditional methods and emerging technologies 

15. Microbial contamination of spices and herbs: Risks and mitigation 

16. Food safety challenges in the era of global food trade 

17. Role of biofilms in foodborne pathogen persistence and resistance 

18. Advances in rapid methods for microbial analysis in food 

19. Microbial risk assessment: Applications in food safety management 

20. Microbial quality of ready-to-eat foods: Issues and control measures 

21. Fermented foods as functional foods: Health benefits and safety considerations

Conducting a Literature Review 

Before diving into the project, conducting a thorough literature review is crucial. 

Exploring scientific journals , research databases, and reputable online sources allows researchers to gain a comprehensive understanding of the current knowledge and gaps in the chosen food microbiology topic. 

Analyzing previous studies and findings provides a foundation for formulating a research question and hypothesis. 

Developing a Research Question and Hypothesis 

A well-defined research question is essential for any food microbiology project. It should be specific and address a gap in knowledge or provide a practical solution to a food safety or quality issue. 

Based on the literature review, researchers can formulate a hypothesis, which serves as a testable prediction or explanation for the expected outcome of the experiment. 

Designing and Planning the Experiment 

Once the research question and hypothesis are established, designing and planning the experiment becomes the next crucial step. 

Researchers need to identify appropriate food samples , research methodologies, and techniques necessary to carry out the study. 

Creating a detailed experimental protocol and considering safety measures ensures a systematic and organized approach to the project. 

Data Collection and Analysis 

With the experimental plan in place, researchers proceed with gathering data by following the designed protocol. 

This may involve collecting food samples, performing microbiological analysis, and utilizing specialized equipment. 

Accurate and detailed record-keeping is essential for subsequent data analysis. Once the data is collected, researchers employ statistical methods and software to analyze the information and draw meaningful conclusions. 

Interpreting and Discussing 

Results After data collection, researchers interpret the gathered information and discuss the results. 

The microbial data is compared with existing literature, and any discrepancies or novel discoveries are analyzed. 

Researchers discuss the implications of their findings, highlighting the significance of the research in the context of food safety , quality, and preservation. 

Presenting the Research 

The final phase of a food microbiology project involves presenting the research findings. 

Researchers can prepare a comprehensive research report or an oral presentation. Creating engaging visual aids, such as charts, graphs, or diagrams, helps convey information effectively and enhances audience understanding. 

Presenting the research to peers, professors, and industry professionals provides an opportunity for valuable feedback and discussion. 

Engaging in a food microbiology project allows researchers to explore the intricate world of microorganisms in our food. 

By choosing an engaging and relevant topic, conducting a thorough literature review, designing and executing experiments, and analyzing the results, researchers contribute to scientific knowledge and address real-world challenges in food safety and quality. 

FAQ Section 

What are some emerging trends in food microbiology research .

Emerging trends in food microbiology research include studying the microbiome of food, exploring the role of microbial metabolites in food quality, and investigating the potential of using beneficial microbes for food preservation. 

How can food microbiology research contribute to food safety? 

Food microbiology research helps identify potential sources of contamination, develop effective preservation techniques, and understand the behavior of pathogenic microorganisms, ultimately leading to improved food safety practices. 

What are some common methods used to analyze microbial contamination in food? 

Common methods for analyzing microbial contamination in food include culture-based techniques, molecular methods like PCR, and next-generation sequencing for microbial identification and characterization. 

Can I conduct a food microbiology project using basic laboratory equipment? 

Yes, many food microbiology projects can be conducted using basic laboratory equipment such as an incubator, autoclave, microscope, and basic microbiological media. However, more specialized projects may require additional equipment. 

Are there opportunities for publishing food microbiology research? 

Yes, there are opportunities to publish food microbiology research in scientific journals and present findings at conferences or symposiums. It allows researchers to share their work with the scientific community and contribute to the field.

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Last Updated on June 2, 2023 by Our Editorial Team

Microbiology

Microbiology is the study of living organisms of microscopic size.

Wednesday, August 27, 2014

Dissertation topics for microbiology students..

• Evaluation of possible bacterial hosts for bacteriophage in soil and aquatic environments.
• Comparative study about antimicrobial activity of tea tree oil , lemon grass oil and Peppermint oil.
• Discovering probiotic bacteria from soil and aquatic environment .
• Efficacy of VAM on Black rot disease in sugarcane.
• Efficacy of VAM on Brown spot disease in sugarcane.
• Physico , chemical,  Bacteriological Analysis Of Well Water  in Madurai District..
• Isolation And Characteristics Of An Antibiotics Producing Bacterium Collected From soil of Madurai..
• Onion Is Associated With Micro-Organisms Which Are Capable Of Causing Spoilage.
• Bacterial Contaminants Associated With Commercial Poultry Feed From Three Different Companies
• Study of air microflora of  Chennai  and its seasonal and locational variation
• Comparison of the efficacy of ordinary washing  and thorough cosmetic  hand washing in the removal of faecal bacteria.
• Microbiological quality assessment of some brands of cosmetics
• Microbiological quality and preservative capacity of commonly available cosmetics  in Tamil Nadu, India.
• Assessment of Microbial quality of commercial herbal cosmetics.
• Microbiological profile of selected samples of "Himalaya" eye cosmetics in Tamil Nadu provinces before and after use.
• Bacteriological profile of skin- moisturizing creams and lotions during use
• The antifungal action of dandruff shampoos.
• The effects of a shampoo containing zinc pyrithione on the control of dandruff.
• Microbiological Examination Of Fresh Milk  Sold In Madurai
• Comparative Analysis Of Microbial Load Of The Madurai  and Chennai  Main Water Production.
• Comparative Study on performance of waste water treatment plant on two different industries.
•  Microbiological study of paper industries influent
• Comparative study on  Bacteriological and mycological profile of fresh vegetables of Madurai and Chennai .
• Microbiology and chemical analysis of food beverages (alcoholic and non-alcoholic) at Chennai.
• Bacteriological analysis of fish and its environment and enzymatic activities of fish isolates
• Bacteriological study of icecream of Chennai .
• Using natural products and essential oils as an alternative for reducing microorganisms toxins in crops, fruits and processed foods
• Comparative Study Of Disinfectant Efficiency Of Ethanol, Bleach And Phenolics Against Pseudomonas Aeruginosa And Staphylococcus Aureus
• The Incidence Of Candidiasis Among Single And Married Women Of Different Age Group
• Isolation And Identification Of Bacteria Associated With Wound Sepsis
• Antimicrobial Activity of Medicinal Plants against
• Study of Anaerobes Vs Aerobes in Wound Infections

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