hiv powerpoint presentation download

Slide sets from talks and workshops

3 February 2024. Related: Advocates , Resources .

The following selected slide sets from over 60 community workshops and other talks were produced by i-Base advocates.

These are free to use for any non-commercial application.

When third-party slides are used these remain the copyright of the original author.

Most talks are by Simon Collins, unless specified otherwise.

4MNet: Women, treatment and our wellbeing

It included co-morbidities that affect us and about living well with HIV.

This was for women living in Kenya, Uganda and the UK.

The talk is also posted to Vimeo online . https://vimeo.com/907478359/ceb50db723

IAS 2023 – UK-CAB Feedback

Community feedback talk from the IAS 2023 conference held in Brisbane, Australia in July 2023.

The slides were based on virtual reporting from the meetings.

Highlights included new cure-related studies, including the Geneva patient. Also lots about HIV complications including the REPRIEVE study that used a statin to reduce cardiovascular risk.

IAS 2023 feedback – PDF talk IAS 2023 feedback – PowerPoint slides

cliniQ conference: PrEP for trans people

These few slides were used as an introduction to aa panel discussion at the  9th CliniQ Conference held on 20 April 2023.

The discussion wanted to cover important issues including the lack of data on trans people in the UK who use PrEP, but also to emphasise that PrEP is just as safe and effective as for cisgender people.

Also that there are no drug interactions between PrEP and gender affirming hormones.

CliniQ PrEP apr 23  – PowerPoint slides CliniQ PrEP apr 23 – PDF slides.

Aidsfonds Stakeholder meeting on cure-related research

This was research workshop held on 10 January 2023 brought together different stakeholders involved in cure-related research.

The couple of slides here highlighted three headline points that were used in some of the group discussions.

AIDSFONDS slides – jan 23  – PowerPoint AIDSFONDS slides – jan 23  – PDF

HIV activism and future HIV drug research

This talk was given as part of the Turkish Civil Society #HIV2022 Conference held from 4 to 6 November 2022 in Istanbul.

Although the main conference was aa face-to-face meeting, this talk was given virtually.

It looks at the role of activism in developing effective HIV drugs and includes information of drugs currently in the pipeline.

Turkey #HIV2022  – PowerPoint Turkey #HIV2022  – PDF

HIV late diagnosis: Article and interview

These links are to an article in a special supplement the medical journal HIV Medicine about late HIV diagnosis from a community perspective.

The authors are all members of the UK-CAB.

The interview is for Medscape about this and other papers from the supplement.

Late diagnosis of HIV in 2022: Why so little change? Collins S,  Namiba A,  Sparrowhawk A,  Strachan S,  Thompson M,  Nakamura H.  HIV Medicine.  2022; 23(11): 1118–1126. doi:10.1111/hiv.13444. https://onlinelibrary.wiley.com/doi/10.1111/hiv.13444

Medscape. Late HIV tied to misclassifications in European surveillance efforts (21 December 2022). https://www.medscape.com/viewarticle/985966

BMJ podcast on mpox

This links to an interview and discussion about the mpox outbreak.

EATG/STEPS cure workshop

This short talk was given on 23 October 2022 as part of a workshop on cure research organised by the EATG at the Glasgow Congress.

It recommends the IAS review of cure-related research, and talks about community issues in that document. This includes the importance of have greater diversity of participants in these studies – including by sex, gender, race, ethnicity and geographic region.

Includes new data from TAG on sex and ethnicity in cure research and the personal impact of joining a cure study.

Download slides – PDF file

HIV science for the community

This slide set covers two European workshops in September 2022 organised by Africa AIDS Foundation (AAF).

They give an introduction to HIV treatment for health workers who have clients who are living with HIV,

Download PowerPoint slides (5 MB) Download PDF  (2 MB)

Research priorities for an HIV cure: the science in context: a community perspective

This talk was given in July 2022 as part of the IAS cure research workshop held in Montreal just before the AIDS 2022 conference.

It included talking about how community advocates are involved in this research, but that this needs to be expanded, Community representation needs to include a wider group of people globally just as cure-related research also needs to be international.

Download PDF file  (12 MB) Link to all talks at the workshop .

HIV treatment and innovations in care

Talk given jointly in June 2022 with Angelina Namiba from the 4MM network. This was for a workshop as part of the 5th UK Conference of people living with HIV.

This covered latest HIV drugs and those expected in the near future.

This included long-acting drugs and the potential for different formulations.

It also talked about standards of care in the UK and the issues linked to HIV and ageing.

Download PowerPoint slides PowerPoint slides (5 MB) Download PDF file  (1.8 MB)

The RIO study

This is a very short talk given to participants on the UK RIO study.

This study uses two bNAbs to see whether viral load can remain undetectable after infusions of bNAbs and a treatment interruption.

Download PDF (300 KB)

Community involvement in the IAS cure strategy

Talk given in May 2022 as part of an IAS webinar.

This focussed on the IAS strategy for cure research, especially the latest 5-year review on recent and future research.

This included input of community advocates in this process.

Download PowerPoint slides  (3.4 MB) Download PDF file  (3 MB)

Feedback from CROI 2022

This is a talk to the UK-CAB in April 2022 about the main new from the recent CROI 2022 conference.

This included new drugs like lenacapavir, bNAbs, long-acting injectable ART, cure-related research, the ANCHOR study and more.

Download PDF (6 MB)

Women and ageing

This talk in March 2022 looked at issues that are important for women getting older with HIV.

This includes being actively involved in care and treatment decisions, medical issues that need monitoring and screening, side effects of ART and the importance of good mental health.

Download PDF (3 MB)

Women, treatment and well-being

Talk on 23 March 2022 for workshops organised by the 4MM project.

This is a general overview about being engaged and active in your own treatment decisions.

It was an introduction to HIV including CD4 counts and viral load, adherence and starting and changing HIV meds.

Download PowerPoint slides (5 MB) Download PDF file (1 MB)

Caution on CAB-LA PrEP and population drug resistance

This was a short talk for the AfroCAB about long-acting cabotegravir injections (CAB-LA) and PrEP.

It is essential that CAB-LA becomes rapidly available as an option to protect against HIV all people globally. Modelling studies show that access can safely provided with only a small risk of drug resistance.

This talk highlights some of these areas with a caution that models should include the possibility that larger percentages of people discontinue CAB-LA, as they have done with oral PrEP.

Download PowerPoint slides (2 MB) Download PDF  (2 MB)

Healthy Living with HIV: what do COVID vaccines mean for people living with HIV

Talk given to a medical workshop on the 2 October 2021 about what vaccines mean for people living with HIV.

PowerPoint slides

Use of generic HIV medicines in the UK

Slides from a short talk on 1 July 2021 at a regional meeting in on Access, Quality and Pricing of HIV Drugs in SEE Countries (Bosnia and Herzegovina, Montenegro, North Macedonia, and Serbia).

i-Base was included to give a perspective from the UK, including that generic HIV drugs are not only widely used, but are an essential strategy to retaining free health care on the NHS.

Generics in the UK –  (PowerPoint slides) Generics in the UK  (PDF)

HIV 40 Years On: perspective of being an active patient

Webinar on 23 June 2021, jointly organised by the Fast Track Cities London and the Worshipful Society of Apothecaries.

This was both to recognise the medical advances for the 40th anniversary of the first publication of HIV cases in the US and to look forward to the goals of “Getting to Zero” by 2030.

Download slides  (PDF) Webcast and info on Fast Track Cities website Webcast on You Tube

Community panel webinar on COVID-19

Roundtable discussion organised by Jim Pickett from AIDS Foundation Chicago and  IAS-USA with six community advocates on difference aspects of COVID-19. No slides but maybe of interest to hear about different international perspectives.

Watch on YouTube .

Introduction to U=U for Trans and MSM HIV support group in Nepal

These slides were for a virtual workshop on 22 May 2021 about U=U for a Trans and MSM HIV support group in Nepal.

Many of the slides are similar to other U=U presentations, but this started with general questions and discussions.

The science showing U=U is a fact came after everyone had a good understanding of what U=U meant in practice.

U=U peer support Nepal – Slides with notes  (PDF 3 MB) U=U peer support Nepal – 22 May 2021 (PDF 8MB)

History of U=U: getting wider awareness

This talk was part of a peer support virtual workshop on 1 May 2021 on U=U.

It was held with 50 community advocates in countries in South East Asia.

Download PDF file . (7 MB)

Treatment interruption in cure research during COVID-19

This talk on 4 March 2021 was part of the always excellent Community Cure Workshops organised by TAG, DARE and other US activist groups before CROI every year.

The talk looked at whether HIV cure research should continue to use analytic treatment interruptions (ATIs) during COVID-19. This is because of concerns that it might increase risks for study participants.

The talk looks at two discussion papers (on mainly from the US and the other mainly from the UK). It includes way to reduces risks (new entry criteria, fewer hospital visits, use of vaccines) and of course the importance of informed consent.

Powerpoint slides (6 MB) – Please contact i-Base PDF file (6 MB) – Please contact i-Base Webcast (with discussion)

Q&A on COVID-19: vaccines and variants

Slides for a zoom talk on 15 February 2021 to Positive Action Foundation Philippines (PAPFI).

This included a short introduction to COVID-19 and potential treatments, but was mainly an update on the safety and efficacy of the new vaccines.

Plus a range of frequent questions over safety of COVID-19 vaccines for HIV positive people.

Powerpoint slides  (.PPT 3MB) PDF slides (PDF 3MB)

Non-technical review of vaccines for COVID-19

This includes that more than 300 candidate vaccines are in studies, 40 in humans, 10 in phase 3, and two approved or almost approved (Pfizer/BioNTech and Moderna/NIH).

It briefly describes the main approaches with summary results on the Pfizer, Moderna and Oxford/Astra-Zeneca vaccines – and the importance of future studies using an active rather than placebo control.

Also, the plans for fair and equitable access globally. And the challenges given that high income countries have already bought or optioned nearly all the first vaccines to be manufactured next year.

Finally, examples of many questions HIV positive people have about the chance of using these vaccines ourselves.

Powerpoint slides .pptx and PDF slides (both about 8 MB)

Link to webcast – STILL TO COME

Lest we forget – Early community involvement in UK HIV response

The community talk included examples of the first reports in the community newspaper Capital Gay and the response from Lesbian and Gay pubs and clubs to collect money for HIV projects. It covers the diversity of community organisations to provide support to different communities of people living with HIV.

This included THT, Body Positive, Birchgrove, Positively Women, Blackliners, Mainliners and many more – and many publications that provided important information and also generated a stronger community network.

PowerPoint slides – (9 MB) Webcast link to both talks . The community talk starts at 16.50.

COVID-19 and upcoming HIV drugs

Workshop on 21 October to the long-standing and dynamic community organisation Positive EAST.

This included this 30-minute talk with Greg Leonard who runs many of the support groups at this project in East London and who recently launched a programme of virtual workshops linked to their FaceBook page.

The talk was given as the second wave of COVID-19 had just become establish in London.

Download PDF slides  – (3 MB) – PDF file Download Powerpoint slides  – (6 MB) – PowerPoint file Watch talk on FaceBook

Introduction to science and HIV research

Workshop as part of EATG STEP course – an introduction to HIV research.

The talk was on 25 September 2020.

It includes research examples that will surprise most people – and therefore show how science can change out mind,

It also includes references to other online resources on treatment literacy.

Download PDF slides . (4.7 MB) Download PowerPoint slides. (4.8 MB)

History of Treatment as Prevention (TasP) and U=U

Workshop as part of EATG STEP course on use of ART as HIV prevention.

The talk highlights key research over the last 22 years that steadily accumulated enough evidence to establish that effective HIV treatment prevents HIV transmission.

Download PDF slides. (5MB) Download PowerPoint slides. (5MB)

Introduction to science (via COVID-19)

This virtual zoom workshop for the EATG general assembly (GA) on 19 September 2020 was about understanding, monitoring, and discussing scientific data for advocacy.

It was a refresher course on different types of research studies using examples from the last nine months of COVID-19 – compressing the equivalent of 40 years of HIV research. This includes data sites (epidemiology), how COVID-19 develops (pathogenesis) and a review of effective treatments and those that should not be used.

In the search for effective treatment, and among thousands of studies, it shows why randomised controlled trials (RCTs) are still needed. Actually, that they are the only way to really know whether or not a promising drug is effective.

Webcast link .

Download PDF of slides . (4.5 MB)

Readability: importance of information that is easy to read for most people

This talk is avoid the importance of good readability scores when producing patient information material – especially in documents for clinical studies.

The talk was given on 3 September 2020 to a working group at Gilead Sciences in the UK and US.

It was based on a talk given at the BHIVA conference in April 2015 (see below).

Download slides (PDF) – 9 MB Readabilty study Gilead Sep 2020 – (PowerPoint – 9.3 MB)

AIDS 2020 feedback (and COVID-19 update no.3)

Feedback to UK-CAB on 28 July 2020 on treatment news from the AIDS 2020 virtual conference and another update on COVID-19.

These studies included positive news on dolutegravir and neural tube defects, longer follow-up on continued weight gain in the ADVANCE study, results using cabotegravir long-acting injections for PrEP and a case reporting HIV remission.

It also included problems navigating the AIDS 2020 website.

The COVID-19 updated summarised important studies reported in the HIV and COVID-19 bulletins from i-Base.

Watch talk on YouTube .

COVID-19 and HIV coinfection: Update 2

A second talk to UK-CAB on 5 June 2020 about advances in research on COVID-19 over the last month.

It also includes statisticians from Public Health England to talk a new report highlighting risk factors for COVID-19, including race, ethnicity and employment.

The main talk includes six new studies on HIV/COVID-19 coinfection, US approval and UK access to remdesivir, reviews of UK research and of promising results with anakinra, anticoagulants, ACE inhibitors, interferon and convalescent plasma. Also controversial results with hydroxychloroquine. Plus updates from BHIVA and EACS statements.

Watch zoom talk on YouTube (via UK-CAB)

UK-CAB COVID19 june 2020  – (PDF – 12MB) UK-CAB COVID-19 june 2020 – (PowerPoint) – please email as large file

COVID-19: summary of current research

Workshop with the European AIDS Treatment Group (EATG) on 15 May 2020.

This was a 30 minute talk about rapidly changing knowledge about COVID-19.

It was also, for EATG members to be able to talk about COVID-19 responses in our different countries and how this has been affecting people living with HIV.

The slides in this talk are similar to the UK-CAB meeting below.

Watch zoom talk on YouTube (via EATG) Powerpoint slides  (.PPT 2.6 MB) PDF slides  (PDF, 2.2 MB)

COVID-19 and HIV coinfection: key research

Talk to virtual UK-CAB Zoom meeting on 1 May 2020. Mainly links to recent research from recent HTB coverage about HIV and COVID-19.

UK-CAB COVID-19 apr 2020 – (PDF – 2MB) UK-CAB COVID-19 apr 2020 – (PowerPoint – 2.2 MB)

CROI 2020 feedback – virtual meeting

Talk as part of virtual UK-CAB Zoom meeting on 30 April 2020.

The talk mainly focused on studies involving new HIV drugs for treatment or prevention (PrEP).

UK-CAB feedback from CROI 2020 (April 2020)   – PDF (17 MB)

Please email for Powerpoint slides as these are too large to post online

Future PrEP: next generation drugs

It reviews a range of new drugs that are being developed both as HIV treatment and PrEP. This might include:

• Long-acting injections (every two months).
• A removable implant that would provide PrEP for over a year, and
• A small oral pill that you might only need to take once a month.

Watch to video on YouTube (15 minute talk) HIV PrEP pipeline feb 2020 – PDF (8MB) HIV PrEP pipeline feb 2020 – PowerPoint (8MB)

U=U: approaches by community and professional organisations in the UK

This talk in January 2020 was given at a U=U conference in Tokyo organised by the Japanese HIV Society.

This talk focused on the ways that BHIVA has shown leadership to publicise U=U. It also includes many examples of how individuals and organisations in the UK have also widened awareness of how HIV treatment prevents sexual transmission.

UK approach to putting U=U in practice  This notes file shows slides in colour with written talk below on each page – PDF (5 MB)

The PowerPoint file is too large to post here but we can send an individual weblink to download if anyone would like this. Please email: [email protected] ).

Community cure meeting: bNAbs and the RIO study

Talk from November 2019 included in the programme of the European AIDS Conference (EACS 2019) held in Basel.

The workshop looked at advances and issues related to HIV cure-related research.

It included information about a study called RIO that will be using two long-acting bNAbs with a treatment interruption. The RIO study is due to start in early 2020.

This workshop was organised by the European Community Advisory Board (ECAB) which is part of the European AIDS Treatment Group (EATG).

RIO Study – EATG cure meeting EACS – Powerpoint slides (3 MB)

RIO Study – EATG cure meeting EACS – PDF (2.5 MB)

Community perspectives of new research

Talk from June 2019 as part of HMRG European HIV Seminar held in Dublin.

The talk looked at advances in treatment over three decades and yet new drugs are still approved with limited data in women, during pregnancy and with TB drugs. Also the delay in access for children.

HMRG 2019 –  PDF slides (7 MB)

CROI 2019 feedback

Set of approximately 60 slides compiled from key studies presented at the recent CROI 2019 medical conference in Seattle.

This presentation was to the UK-Community Advisory Board (UK-CAB) meeting on 6 April 2019.

CROI 2019 feedback UK-CAB  – PDF slides (5.6 MB)

Is rapid ART right for all?

Talk given on the last day of the 25th BHIVA conference held in Bournemouth (BHIVA 2019).

The talk includes reports from two clinics where people are offered ART when they have their first appointment after diagnosis – often on the same day. All other services and tests and services are reorganised to enable this.

Webcast link – (At approx 1hr2mins if doesn’t load automatically)

Rapid ART for all?  – PDF slides. (3 MB)

Rapid ART for all? – notes – PDF with notes. (3 MB)

Ethical issues and informed consent in HIV cure research studies: EATG workshop, Glasgow 2018

A talk looking at a common disconnect between researchers and participants in HIV cure-related studies.

More researchers expect no or little clinical benefit. Many participants still think they had a slight or more significant hope that they might be cured.

ECAB cure – Glasgow 2018  – PDF (100 Mb)

20th National HIV Nurses Association (NHIVNA) conference, July, Brighton

Evidence for U=U: the PARTNER study and Prevention Access Campaign

Talk as part of the pre-conference workshop about the evidence over twenty years for the U=U campaign.

This included the London version: A=A: Ain’t no viral load, ain’t no risk of HIV.

NHIVNA U=U talk 27 June 2018   (PDF – (7.2 MB)

NHIVNA U=U talk with NOTES  (PDF – 3.4 MB)

4th National Conference of People Living with HIV (October 2017)

Treatment update for London HIV positive conference.

Topics cover evidence for U=U and treatment updates for new drugs.

This talk was largely based on the talks given at the HIV Scotland conference below.

UK HIV+ conference 2017 Treatment update  (PDF – 8.5 MB)

Paediatric HIV pipeline drugs (October 2017)

Talk on pipeline HIV drugs for children given by Polly Clayden to a closed meeting of the IMPAACT trial network.

This is a focus on the paediatric pipeline, that usually takes several years (at least) after a drug is approved for adults.

This also usually occurs in age bands – first adolescents, then children and finally infants and babies. Many HIV drugs, however, are never approved for the youngest children.

Paediatric ART pipeline IMPAACT – (PDF – 950 Kb)

Positive Peoples Forum – HIV Scotland (July 2017)

Two talks for the annual HIV positive conference held in Glasgow this year.

Undetectable = untransmittable (U=U)  – PDF (3.3 MB)

A talk about HIV treatment as prevention (TasP) that reviews the evidence for why so many doctors, scientist and community groups say that an undetectable viral load means you cannot transmit HIV to partners.

This was included as an idea in US guidelines in 1998 and has been supported by accumulating evidence from different studies over the last 20 years.

Short update about new HIV meds in development, drug pricing in the UK, cure research and PrEP.

This includes the HIV lifecycle to show how current HIV drugs work at different sites and the new targets for the most promising upcoming drugs.

A couple of slides are included on drug pricing in the UK and how generics affect this.

CROI 2017: feedback to UK-CAB (April 2017)

Short talk to feedback key studies for the UK-CAB.

Mainly to cover cure research, new drugs and treatment strategies.

CROI 2017 feedback UK-CAB  – PDF (5 MB)

Review of i-Base treatment information services (April 2016)

Talk given by Robin Jakob to BHIVA conference about the phoneline and Q&A services.

http://www.bhiva.org/160420RobinJakob.aspx

Reference: HIV treatment information and advocacy 2014/15: continued demand for community support services . R Jakob, R Trevelion, J Dunworth, M Sachikonye and S Collins. 22nd Annual BHIVA Conference, 19-22 April 2016, Manchester. Oral abstract O5. HIV Medicine, 17 (Suppl. 1), 3–13. HIV Medicine 17, 4, 2016. Treatment advocacy – 2014-15 – Robin Jakob – PDF slides. http://www.bhiva.org/documents/Conferences/2016Manchester/AbstractBook2016.pdf

HIV testing: who, how and why? (September 2015)

Martin was one of the key doctors whose skills, energy and determination over the last 20 years were responsible for ensuring that HIV positive people in the UK received such high standards of care.

He was also a scientist and researcher, activist and friend. Martin was an incredibly kind, passionate, popular and modest man and his partner Adrian together with his family, friends and colleagues have launched this foundation to celebrate and continue his work.

HIV Testing Martin Fisher foundation talk  – PowerPoint (2 Mb)  HIV testing MFF  – PDF (2 Mb)

Watch webcast on Vimeo .

2015 treatment update: good time for a change (September 2015)

• Impact of START study on BHIVA and WHO guidelines.
• Absolute and relative benefits from earlier treatment.
• TasP and PrEP.
• Immune inflammation.
• ART in acute infection and cure research.

UK HIV conference 2015  – PDF (900 Kb)  UK PWA conference 2015  – PowerPoint (1.1 Mb)

START study results and new BHIVA guidelines – UK-CAB (July 2015)

• The question of when to start HIV treatment.
• The differences between observational studies and randomised controlled trials (RCTs).
• Design of the START study.
• Top-line results and implications.
• Draft UK BHIVA treatment guidelines: key changes and how to comment.

PowerPoint slides UK-CAB july 2015 (250 Kb)  PDF file UK-CAB july 2015  (160 Kb)

Treatment Q&A at Bloomsbury Clinic (May 2015)

The talk included a doctor, a study researcher and an advocate.

PowerPoint  – (4.5 MB)  PDF  – (4.8 Mb)

Are patient information leaflets for research studies too difficult to read? (April 2015)

It was a small study lead by advocates at i-Base and was selected by the conference for an oral presentation (Abstract O_4).

The study calculated readability scores from nine ongoing studies and compared them to two community-produced examples.

The presentation was also awarded one of two prizes from BHIVA and Mediscript for the best oral or poster research on social science or community-based work.

PowerPoint slides (1.6 Mb)   PDF version  – (1.1 Mb)

Community feedback from CROI 2015 – UK-CAB (April 2015)

• The PROUD and IPERGAY studies
• Other PrEP studies including PARTNERS PrEP and FACTS 001.
• TAF – new version of TDF
• Attachment inhibitors and maturation inhibitors.

PowerPoint file – (5.3 Mb)   PDF slides file  – PDF (3MB)   6-up handout  – PDF (1.2 Mb)

Seminar on PrEP and chemsex – Copenhagen (March 2015)

Talk about recent and current experiences in the UK about PrEP.

This included community involvement in the PROUD study, the IDMC recommendation in October 2014 to offer PrEP to all participants, and community responses since.

Plus a short update on PrEP studies at CROI 2015.

The meeting was organised by the Danish HIV organisation  AIDSFONDNET  and included HIV positive and HIV negative community activists and health professionals.

PrEP talk copenhagen  – PDF (5.9 Mb)

Imperial College BSc Global Health course (Jan 2015)

PDF  file (1.5 MB)

Please email for higher resolution or PowerPoint files.

Imperial College medical students (Dec 2014)

Talk to 300 first-year medical students at Imperial College about role of patient/doctor partnership and communication. Also how treatment literacy can support people to take an active role in their healthcare.

Includes references to early US activism, including the Denver Principles (1983) and personal perspectives as a patient activist in the UK.

PowerPoint with notes  (6.1 MB)  PDF  file (6.1 MB) – please email for higher resolution files .

PrEP: a community perspective (November 2014)

Talk about PrEP (Pre-Exposure Prophylaxis) from the HIV Conference in Glasgow. The talk looks at the history of PrEP and a few myths.

Although optimal use will be in situations where HIV risk is high, PrEP – just like TasP (Treatment as Prevention) – may help reduce stigma against HIV.

It may also help improve quality of life by reducing fear and anxiety about HIV.

Powerpoint with notes (7.5 MB) PDF file  (2.4 MB)  PrEP talk slide notes  Word.doc (50 Kb)

This talk is available as a webcast. https://vimeo.com/244353226

Collins S.  Journal of the International AIDS Society  2014,  17(Suppl 3) :19522  Conference abstract .

Option to use ART in early HIV infection (Oct 2014)

Talk about the importance for people who are diagnosed within 6 months of infection to be given the choice of using ART, irrespective of CD4 count. This short window may be very different to starting at any time after 6 months and yet many people do not have this discussion. Talk for BHIVA autumn conference 2014.

BHIVA 2014 early ART talk  – PDF (200 Kb)  BHIVA 2014 early ART talk  – PowerPoint (400 Kb)

UK-CAB advocates training (Sep 2014)

• Introduction to science and importance of evidence-based medicine.  Powerpoint slides  (1 MB) and  PDF  (1.1 MB)
• Tips for writing patient-friendly information –  Powerpoint slides  (200 Kb) and  PDF file  (280 Kb)

Two talks for this 4-day UK-CAB advocacy training .

Health service constraints on HIV care – the research agenda: a UK perspective (March 2014)

Short presentation to European CHAIN research network to mark the completion of this five-year research programme.  PDF  and  PowerPoint  (500 Mb)

Community views on long-acting ARVs (March 2014)

Short presentation to US NIH mixed stakeholder meeting (researchers, regulators, industry and community) on the development of long-acting HIV meds, especially injections.  PowerPoint (600 Mb) and PDF  (400 Mb),

Talk to medical students (Nov 2013)

Talk to 300 first-year medical students at Imperial College about how HIV activism has affected patent involvement in care. Powerpoint (with notes)  (6 MB) and   PDF (slides only)  (6 MB)

Hot topics in HIV treatment (Oct 2013)

Talk to UK HIV positive conference on six important topics that could change HIV care in the next year: Access to ARVs and generics in the new NHS/When to start and why guidelines differ… /Treatment as Prevention/New HIV drugs: Stribild, dolutegravir, TAF, GSK-744/Hepatitis C and sexual transmission/Hepatitis C: new HCV drugs (DAAs) –  PDF  (98 Kb)

UK-CAB advocates training (Oct 2013)

• Introduction to science and importance of evidence-based medicine. Powerpoint slides  (1 MB) and  PDF  (1.1 MB)
• Tips for writing patient-friendly information –  Powerpoint slides  (200 Kb) and PDF file (280 Kb)

HIV and cancer (April 2013)

This talk highlights that it is mainly because HIV treatment is so effective that we are living long enough for cancer to be a complication. For nearly all cancers, older age is one of the key risk factors.

HIV makes the risk of some cancers slightly higher than the general population. These risks are still relatively unlikely events. To reduce these risks, the same lifestyle changes as the general population are just as important for HIV positive people – perhaps more so.

From a personal perspective, managing a cancer diagnosis is serious and meant you have to make your health a main priority to give yourself the best chance. This gives many people a new chance to make the most of their time, irrespective of the outcome.

PowerPoint  (135 Kb)  PDF  (70 Kb)

HIV cure research: pieces in the puzzle (January 2013)

This non technical talk explains the science behind four key approaches to cure research. This is a puzzle and all four are likely to be needed on the way to finding a cure.

The context includes the context for the research, background on why a cure is difficult and ethical issues related to this research.

PowerPoint  (2.5 Mb)  PDF  (3.4 Mb)

Budget issues affecting treatment choice: the London tender process (November 2012)

PowerPoint slides November 2012  – (180 Kb)  PDF file  (140 Kb)  Text notes  (Word.docx)

This talk is available as a webcast on the conference website:  MAC webcast  –  PC webcast .

IAS July 2012 – Washington

Feedback from the International AIDS conference held in Washington in July 2012:   PDF  (400 Kb)  PowerPoint  (975 Kb)

Slides for a talk at a feedback meeting organised by the  UK Consortium .

CROI February 2010 – San Francisco

A talk on community perspectives from the Retroviruses Conference (CROI) given to the feedback meetings organised by BHIVA.

• BHIVA CROI community slides reduced PDF (4MB)

Treatment Action Campaign

• Factsheet: measures used for CD4 and viral load (millilitre, microlitre, mL, mm3, μL) PDF  Jan 2010

Showing the different measures for CD4 counts and viral load including millilitre, microlitre, mL, mm3, μL). Also, showing why you still have many millions of CD4 cells in your body even at very low CD4 counts.

• Pharmacology: how drugs are absorbed in your body PDF  – Jan 2010

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• 1. HivInfection &AIDs
• 3. overview
• 4. Hiv Disease human immunodeficiency virus implies the entire course of HIV infection, from asymptomatic infection and early symptoms to AIDS a chronic condition, controllable with medications and strict adherence to treatment recommendations
• 5. AIDS Acquired immunodeficiency syndrome Most severe form of a continuum of illnesses associated with HIV infection If untreated, it causes slow degeneration of the immune system with the development of opportunistic infections and malignancies
• 6. Etiology & pathophysiology
• 8. Causative agent: a retrovirus that infects and depletes the CD4+ T-helper lymphocytes (one of the “protector” cells of the immune system) B lymphocytes secrete antibodies into the body fluids, or humors (humoral immunity) T lymphocytes can penetrate living cells (cell-mediated immunity)
• 9. Monocytes & macrophages, whose role is to present antigen to T cells, thereby initiating the body's immune response, are also infected by HIV Once HIV has entered the body, it attaches most efficiently to CD4+ molecules, which are predominantly located on the cell membrane of T4 helper lymphocytes After penetrating the cell membrane, the HIV genome and enzymes are released in the cell and integrated into the lymphocyte's genome
• 11. The result of this reproductive process is the production of many new HIV virions and cell death for the T4 helper lymphocyte With progressive invasion of HIV, cellular and humoral immunity declines and opportunistic infections that characterize this disease begin to emerge
• 13. Vaginal secretions
• 16. sexual contact (vaginal or anal intercourse, oral sex)
• 18. Homosexual or bisexual men I.V. drug users Transfusion and blood product recipients (before 1985) Heterosexual contacts of HIV-positive individuals Newborn babies of mothers who are HIV-positive
• 19. STages of HIV Disease
• 21. Adenopathy
• 22. Pharyngitis
• 24. Although most patients seek clinical care, few are diagnosed because the symptoms mimic a common flu During this phase the immune system is compromised by a sudden decrease in T4 helper cells and an increase in viral load for a brief period before returning to baseline
• 25. Seroconversion occurs when the person has developed enough antibodies to HIV that the serologic test is positive Usually occurs 4 to 6 weeks after acute HIV infection
• 26. HIV Asymptomatic CDC Category A: More Than 500 CD4+ T Lymphocytes/mm3 By about 6 months, the rate of viral replication reaches a lower but relatively steady state that is reflected in the maintenance of viral levels at a kind of “set point” Set point varies greatly and dictates the subsequent rate of disease progression
• 27. On average, 8 to 10 years pass before a major HIV-related complication develops Patients feel well and have few if any symptoms Apparent good health continues because CD4+ T-cell levels remain high enough to preserve defensive responses to other pathogens
• 28. HIV Symptomatic CDC Category B: 200 to 499 CD4+ T Lymphocytes/mm3 The number of CD4+ T cells gradually falls Category B consists of symptomatic conditions in HIV-infected patients that are not included in the conditions listed in category C
• 30. The condition is considered to have a clinical course or to require management that is complicated by HIV infection
• 33. Housing
• 34. Food stamps A CD4+ percentage of less than 14% of the total lymphocytes is consistent with an AIDS diagnosis. One complication of advanced HIV infection is anemia, which may be caused by HIV, opportunistic diseases, or medications
• 36. Clinical manifestations
• 37. Pulmonary Persistent cough with and without sputum production SOB chest pain Fever Pneumocystiscarinii pneumonia (PCP) -most common bacterial pneumonia (CAP) M. tuberculosis disseminated Mycobacterium avium complex CMV Histoplasma Kaposi's sarcoma Cryptococcus Legionella other pathogens
• 42. Shigella
• 43. Campylobacter
• 44. Entamoebahistolytica
• 45. C. difficile
• 47. M. avium complex
• 48. herpes simplex
• 49. Strongyloides
• 50. Giardia
• 51. Cryptosporidium
• 52. Isospora belli
• 53. ChlamydiaDiarrhea Weight loss Anorexia Abdominal cramping Rectal urgency (tenesmus) From enteric pathogens:
• 57. Oral manifestations White plaques on oral mucosa, particularly in the posterior pharynx & angular cheilitis from Candida albicans of mouth & esophagus Vesicles with ulceration from herpes simplex virus White, thickened lesions on lateral margins of tongue from hairy leukoplakia Oral warts due to human papillomavirus and associated gingivitis Periodontitis progressing to gingival necrosis Aphthous ulcers of unclear etiology -painful, solitary lesions with raised margins
• 62. Central nervous system Cognitive, motor, behavioral symptoms (AIDS dementia complex/HIV encephalopathy) mental slowing, impaired memory & concentration, loss of balance, lower extremity weakness, ataxia, apathy, social withdrawal May be caused by CNS toxoplasmosis, cryptococcal meningitis, herpes virus infections, CMV encephalitis, progressive multifocal leukoencephalopathy, CNS lymphoma. Sensory symptoms (distal symmetric polyneuropathy) -demonstrated by numbness, tingling, neuropathic pain
• 75. Diagnostic evaluation
• 76. Positive blood test for HIV Enzyme-linked immunosorbent assay (ELISA) -serologic test for detecting antibody to HIV Western blot test - used to confirm a positive result on ELISA When infected with HIV, it usually takes the body up to 12 weeks to develop enough antibody to HIV for the test result to be positive, resulting in a false-negative test if evaluated early.
• 78. candidiasis of esophagus
• 80. A higher number (greater than 750,000 copies/mL) indicates greater viremia
• 81. High viral loads are usually found in acute seroconversion and late disease, but also occur when patients have another infectious process in the body
• 82. A viral load test result can be undetectable, meaning the amount of virus is less than 50 copies/mL
• 83. This does not indicate that the body is free of HIV
• 86. Hyperlipidemia
• 87. Insulin-resistance
• 89. management
• 90. General considerations
• 91. Treatments are available for the underlying immunodeficiency and are usually successful when patients receive at least 90% of doses Patient education that stresses adherence to treatment and monitoring adherence are essential elements of treatment success Treatment is available for some opportunistic infections and other diseases associated with AIDS
• 92. Specific treatment
• 93. haart Highly active antiretroviral therapy Consists of medications that belong to four different classifications because they act to prevent HIV replication at four different points along the replication process. Standard: take a minimum of 3 different drugs from at least 3 different drug classifications
• 96. transformed HIV from a terminal illness to a chronic illness for many patients
• 98. Supportive Care Treatment of reversible illnesses Nutritional support Palliation of pain Evaluation and management of psychological and social aspects of HIV/AIDS infection Treatment to relieve symptoms (cough, diarrhea) Antidepressant drugs; psychiatric interventions
• 99. Nursing Managment
• 100. Nursing assessment
• 102. constitutional s/sx
• 103. recent infections
• 104. + blood test for HIV antibodies
• 105. most recent CD4+ count
• 112. Activity intolerance Disturbed body image Fatigue Hopelessness Hyperthermia Imbalanced nutrition: Less than body requirements Impaired oral mucous membrane Impaired skin integrity Impaired tissue integrity
• 113. Ineffective coping Ineffective health maintenance Ineffective protection Ineffective sexuality patterns Interrupted family processes Noncompliance (treatment regimen) Powerlessness Risk for deficient fluid volume Risk for infection Social isolation
• 114. Key outcomes
• 115. The patient will: verbalize the importance of balancing activity, as tolerated, with rest verbalize feelings about a changed body image express that he has more energy make decisions on his own behalf maintain a normal body temperature maintain current weight or achieve ideal weight (patient's) oral mucous membranes will remain intact
• 116. The patient will: voice feelings about changes in sexual identity (patient's) wounds & lesions will heal without complications site of impaired tissue will have reduced redness, swelling, pain use support systems to assist with coping perform health maintenance activities according to the level of his ability demonstrate use of protective measures, including conserving energy, maintaining a balanced diet, getting plenty of rest
• 117. The patient will: (family will) state ways to support & assist the patient comply with the treatment regimen express feelings of control over his condition & situation maintain adequate fluid balance experience no fever, chills, or other signs or symptoms of illness maintain peer & family relationships
• 118. Nursing interventions
• 124. Patients must understand that medication regimens must be followed closely & may be required for many years, if not throughout lifeUrge the patient to inform potential sexual partners & health care workers that he has HIV infection
• 126. Preventing AIDS transmission
• 130. http://nurseRD.blogspot.com www.authorstream.com/reynel89/Nursing www.slideshare.net/reynel89/slideshows THANK YOU!Have a nice day : ) - RDG

Aug 24, 2014

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HIV 101. Adapted from curriculum by Tucson Interfaith HIV/AIDS Network. HIV/AIDS Info & History. In 1981, 1 the first cases of AIDS were identified among gay men in the US. However, scientists later found evidence that the disease existed in the world as early as 1959.

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HIV 101 Adapted from curriculum by Tucson Interfaith HIV/AIDS Network

HIV/AIDS Info & History • In 1981,1 the first cases of AIDS were identified among gay men in the US. However, scientists later found evidence that the disease existed in the world as early as 1959. • The first documented case of HIV was traced back to 1959 using preserved blood samples, which were analyzed in 1998. • In first-world countries, AIDS is now a chronic disease, but this was not the case in the past. • AIDS is 100% preventable, and yet there were 56,300 new infections in 2006 in the US alone.2 1. Advert.org 2. Centers for Disease Control and Prevention

AIDS is a Global Problem • 33 million people worldwide have HIV/AIDS. • 571,378 people in the United States are HIV-positive. • New HIV infections occur every 6 seconds.1 1. UNAIDS

From Terminal to Chronic Life Expectancy 3 Months 1980s Today 27 Years…and counting! Infection

Statistics • Worldwide: Over 33 million people are living with HIV.1 • 50 percent are women.1 • 2 million are children under age 15 years.1 • United States: Over 570,000 people are living with HIV.2 1. UNAIDS 2. Centers for Disease Control and Prevention

An individual is at risk if she or he… • Has had unprotected sex—ever. • Has had multiple partners within one year. • Has shared needles, or if the partner has shared needles. • Has had a sexually transmitted disease, or sexually transmitted infection—ever. • Uses alcohol or drugs. • This is an indirect risk factor as it causes impaired judgment, which can lead to high-risk behaviors.

H - I - V - Human Immunodeficiency Virus Definitions

A - Acquired I - Immune D - Deficiency S - Syndrome Definitions

Normal Immune Response T-cells make antibodies Virus binds to T-cells Antibodies bind to virus Virus T-cells Antibodies kill virus Normal response: Virus invades blood stream and binds to lymphocytes. Lymphocytes make antibodies to the virus. Antibodies bind to the virus and destroy the virus. Virus

Immune Response to HIV HIV destroys T-cells (CD4 cells) HIV T-cells cannot produce antibodies Cannot destroy virus

Possible Minor Symptoms What’s the difference between HIV and AIDS? • HIV, a virus, eventually causes AIDS, a syndrome. Spectrum of HIV Infection Blood tests positive Healthy, HIV+ can last for years Symptomatic HIV/AIDS

T-Cell Count • If 1,200 or higher, the individual has a normal immune system. • If 800 or less, the immune system is weakened and individual is susceptible to infection. • If 200 or less, AIDS is diagnosed. • Once a person is diagnosed with AIDS, she or he is always categorized as having AIDS, even if her or his T-cell count increases.

Criteria for Diagnosing AIDS • A CD4 cell (type of T-cell) count of 200 or less, or • One opportunistic infection. • An opportunistic infection is an infection that typically does not affect individuals with normal immune systems.

Mycobacterium Avium Complex Salmonellosis Syphilis and Neurosyphilis Tuberculosis Bacillary angiomatosis Aspergillosis Candidiasis Coccidioidomycosis Cryptococcal Meningitis Histoplasmosis Kaposi’s Sarcoma Systemic Non-Hodgkin’s Lymphoma Primary CNS Lymphoma Cryptosporidiosis Isosporiasis Microsporidiosis Pneumocystis Carinii Pneumonia Toxoplasmosis Cytomegalovirus Hepatitis Herpes Simplex Herpes Zoster Human Papillomavirus Molluscum Contagiosum Oral Hairy Leukoplakia Progressive Multifocal Leukoencephalopathy AIDS Dementia Complex Peripheral Neuropathy Apthous Ulcers Malabsorption Depression Diarrhea Thrombocytopenia Wasting Syndrome Idiopathic Thrombocytopenic Purpura Listeriosis Pelvic Inflammatory Disease Burkitt’s Lymphoma Immunoblastic Lymphoma Valley Fever MRSA Opportunistic Infections Source: AIDS Education Global Information System

Fluids and HIV Transmission

Fluids thatDO transmit HIV: Blood Semen Vaginal Fluid Breast Milk (in order of the highest concentration of HIV) Fluids that DO NOT transmit HIV: Saliva Tears Mucus Urine Sweat Feces Fluids that can transmit HIV

Relative Risk High risk: • Sharing needles • Unprotected sex • Breast feeding Lower risk: • Protected sex • Any opportunity for exchange of body fluids No risk: • Casual contact

Universal Precautions • Wash your hands! • Disinfect utensils and living space. • Use barriers—preferably latex. HIV cannot be spread through casual contact, but these are good practices for preventing opportunistic infections.

Barriers include: • Latex Gloves • Latex Condoms • Sheepskin condoms do NOT protect! • Latex Dental Dams • Anything that protects your skin from a fluid

Prevention • What is the only 100% effective way to prevent HIV infection? ABSTINENCE! • What does abstinence include? • Do not have sex with infected, possibly infected, or multiple partners. • Do not share needles.

Other Prevention Options • If not abstinence, barriers can greatly reduce the risk of HIV transmission. • Use latex condoms and water-based lubricants or dental dams.

Testing • The test is for antibodies against HIV, not for the virus itself. • It can take up to three months for the body to produce antibodies against HIV. • A negative test result may mean recent infection. It is possible to infect others during this stage. • An individual should be tested three months after possible exposure to guarantee an accurate result.

Timeline Test Date New Test Date Three-month window from first exposure Three-month window from second exposure Secondexposure First exposure

Real Life Application • At a party three months ago, I engaged in some high-risk behaviors….When should I get tested? • Before I came here today, I got high with a used needle…now what do I need to do? Avoid the possibility of infecting others! Today! Get tested in 3 months!

The ONLY way to know is to get TESTED! Find a Testing Site Near You! • Go to www.hivtest.org • Enter your zip code. • Instantly receive list of all HIV-testing sites in your area.

Treatment • Today, in the US, HIV/AIDS is a chronic disease. • Anti-retroviral drugs are used in combination, known as Highly Active Anti-Retroviral Therapy (HAART). • Side effects can be severe, but the risks of not being treated are more severe. • Cornell University estimates the monthly cost of treatment as $2,100, with a lifetime cost of treatment of $618,900.

What can I do to protect myself? What can I do to help or protect others? What can I do to protect my community and the world we live in? Call to Action

Behave Responsibly and GIVE to the United Methodist Global AIDS Fund UMCOR Advance #982345 Visit: www.umglobalaidsfund.org

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It's important to keep in mind, though, that while you're free to use this web version of PowerPoint to create your slides and edit templates, there are certain features it doesn't have that you can find on the paid version. For instance, you can access only a handful of font styles and stock elements like images, videos, icons, and stickers. Designer is also available for use on up to three presentations per month only (it's unlimited for premium subscribers). When presenting, you won't find the Present Live and Always Use Subtitles options present in the paid plans. The biggest caveat of the free version is that it won't get any newly released features, unlike its premium counterparts.

Method #2: Install Microsoft 365 (Office) To Your Windows

Don't fancy working on your presentation in a browser? If you have a Windows computer with the Office 365 apps pre-installed or downloaded from a previous Office 365 trial, you can use the Microsoft 365 (Office) app instead. Unlike the individual Microsoft apps that you need to buy from the Microsoft Store, this one is free to download and use. Here's how to get free PowerPoint on the Microsoft 365 (Office) app:

• Search for Microsoft 365 (Office) on the Microsoft Store app.
• Install and open it.
• Sign in with your Microsoft account. Alternatively, press "Create free account" if you don't have one yet.
• Click on Create on the left side panel.
• Select Presentation.
• In the PowerPoint window that opens, log in using your account.
• Press Accept on the "Free 5-day pass" section. This lets you use PowerPoint (and Word and Excel) for five days — free of charge and without having to input any payment information.
• Create your presentation as usual. As you're using the desktop version, you can access the full features of PowerPoint, including the ability to present in Teams, export the presentation as a video file, translate the slides' content to a different language, and even work offline.

The only downside of this method is the time limit. Once the five days are up, you can no longer open the PowerPoint desktop app. However, all your files will still be accessible to you. If you saved them to OneDrive, you can continue editing them on the web app. If you saved them to your computer, you can upload them to OneDrive and edit them from there.

Method #3: Download The Microsoft PowerPoint App On Your Android Or iOS Device

If you're always on the move and need the flexibility of creating and editing presentations on your Android or iOS device, you'll be glad to know that PowerPoint is free and available for offline use on your mobile phones. But — of course, there's a but — you can only access the free version if your device is under 10.1 inches. Anything bigger than that requires a premium subscription. If your phone fits the bill, then follow these steps to get free PowerPoint on your device:

• Install Microsoft PowerPoint from the App Store or Google Play Store .
• Log in using your existing Microsoft email or enter a new email address to create one if you don't already have an account.
• On the "Get Microsoft 365 Personal Plan" screen, press Skip For Now.
• If you're offered a free trial, select Try later (or enjoy the free 30-day trial if you're interested).
• To make a new presentation, tap the plus sign in the upper right corner.
• Change the "Create in" option from OneDrive - Personal to a folder on your device. This allows you to save the presentation to your local storage and make offline edits.
• Press "Set as default" to set your local folder as the default file storage location.
• Choose your template from the selection or use a blank presentation.
• Edit your presentation as needed.

Do note that PowerPoint mobile comes with some restrictions. There's no option to insert stock elements, change the slide size to a custom size, use the Designer feature, or display the presentation in Immersive Reader mode. However, you can use font styles considered premium on the web app.

Method #4: Use Your School Email Address

Office 365 Education is free for students and teachers, provided they have an email address from an eligible school. To check for your eligibility, here's what you need to do:

• Go to the Office 365 Education page .
• Type in your school email address in the empty text field.
• Press "Get Started."
• On the next screen, verify your eligibility. If you're eligible, you'll be asked to select whether you're a student or a teacher. If your school isn't recognized, however, you'll get a message telling you so.
• For those who are eligible, proceed with creating your Office 365 Education account. Make sure your school email can receive external mail, as Microsoft will send you a verification code for your account.
• Once you're done filling out the form, press "Start." This will open your Office 365 account page.

You can then start making your PowerPoint presentation using the web app. If your school's plan supports it, you can also install the Office 365 apps to your computer by clicking the "Install Office" button on your Office 365 account page and running the downloaded installation file. What sets the Office 365 Education account apart from the regular free account is that you have unlimited personal cloud storage and access to other Office apps like Word, Excel, and Outlook.

Read the original article on SlashGear .

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