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Sheridan Grant

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Sheridan is a writer from Hamilton, Ontario. She has a passion for writing about what she loves and learning new things along the way. Her topics of expertise include skincare and beauty, home decor, and DIYing.

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About Thesis Nootropics

Hands up if you guzzle five coffees a day to stay awake, have tried all the supplements in the book desperate to improve your headspace, and aren’t interested in prescribed medications. Designed to increase focus , Thesis nootropics might be for you. 

Thesis offers a customized blend of ingredients designed to optimize your cognitive function , with personalized details that tackle your specific needs. Nootropics boost brain performance in the same way a stimulant would, without the common negative effects. 

A study published in the Journal of Alzheimer’s Disease found that nootropics may help improve cognitive function in people with Alzheimer’s disease.

Interested in finding out more about the brand and how it works? Leaf through our Thesis Nootropics review. We’ll be your guide through the company and the process, as well as details on the treatments, highlights from customer reviews, answers to important FAQs, and more, to help you decide if it’s worth the try.

Pros and Cons

• Multiple cognitive benefits: Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function.
• Long-term effects: On top of short term benefits for daily life, Thesis nootropics ingredients are designed to impact the brain in the long-term.
• Personalized recommendations: Thesis Nootropics makes personalized recommendations based on your goals and unique brain chemistry.
• Potential side effects: The most common side effects to watch out for when you start taking Thesis Nootropics include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
• Need to stop taking if issues arise: If you experience a headache or an upset stomach that won’t go away while taking their nootropics, Thesis recommends that you stop taking them.

What is Thesis Nootropics?

Nootropics are nutrient compounds and substances that are known to improve brain performance , such as caffeine and creatine. They help with issues that affect motivation, creativity, mood, memory, focus, and cognitive processing.

Nootropics are the ideal addition to an already healthy lifestyle that consists of exercise, proper nutrition, and enjoyable activities.  Thesis nootropics are carefully formulated to target specific needs, ranging from energy to creativity. The brand focuses on safety, ensuring that all supplements adhere to FDA guidelines and go through multiple clinical trials. 

How Thesis Nootropics Works

With all that being said, you may be wondering how Thesis provides users with an option that is specific to their needs. Fortunately, the process is simple and hassle free. Here’s how it works:

• Take the Thesis nootropics quiz
• Answer questions about your basic information
• Receive personalized recommendations 
• Get your starter kit for $120 , or $79 monthly when you subscribe 

After that, you’ll select one formula to take each week, taking one day off in between each different option. You’ll also track your results in the daily journal over the month to see how they affect your daily life. 

From there, it operates as a subscription service. Users will be able to optimize their next shipment by telling the brand which formulas worked best.

If you don’t like any of the blends in your box, let the company know and they’ll switch it for something that’s a better fit for your lifestyle, genetics, and goals.

Thesis Nootropics Ingredients

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties. Here are some of the key ingredients in Thesis Nootropics:

• Cognizin (Citicoline) : Cognizin is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• L-Theanine : L-Theanine is an amino acid that is found in green tea, and is known for its ability to promote relaxation and reduce stress and anxiety.
• Lion’s Mane Mushroom : Lion’s Mane Mushroom is a type of medicinal mushroom that is believed to have cognitive-boosting properties, including improved memory and focus.
• Rhodiola Rosea : Rhodiola Rosea is an adaptogenic herb that is known for its ability to reduce stress and fatigue, and improve mental clarity and cognitive function.
• Ashwagandha : Ashwagandha is an adaptogenic herb that is known for its ability to reduce stress and anxiety, and improve memory and cognitive function.
• Phosphatidylserine : Phosphatidylserine is a type of phospholipid that is found in high concentrations in the brain, and is believed to support cognitive function, including memory and focus³
• Alpha-GPC : Alpha-GPC is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• TAU (uridine): TAU is a blend of uridine, choline, and DHA, which is believed to support brain health and cognitive function.
• Artichoke extract : Artichoke extract is believed to enhance cognitive function by increasing levels of acetylcholine, a neurotransmitter that is important for memory and learning.
• Dynamine : Dynamine is a type of alkaloid that is believed to enhance cognitive function by increasing levels of dopamine, a neurotransmitter that is important for mood and motivation.

Overall, the ingredients in Thesis Nootropics are carefully chosen for their cognitive-boosting properties, and are designed to work together to enhance overall brain health and cognitive function.

Thesis Nootropics Health Benefits

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties, and offer numerous health benefits. Here are some of the health benefits of Thesis Nootropics:

• Increased cognitive energy : One of the key benefits of Thesis Nootropics is increased cognitive energy, which can help improve productivity, mental alertness, and motivation, as it contains cognizin .
• Enhanced mental clarity : Another benefit of Thesis Nootropics is enhanced mental clarity,given from Lion’s Mane Mushroom which can help reduce brain fog and improve focus.
• Improved memory and learning abilities : Thesis Nootropics contains ingredients that are believed to improve memory and learning abilities, like Phosphatidylserine , which can help users retain information more effectively.
• Elevated mood : Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression, thanks to ingredients like L-Theanine and Ashwagandha .
• Lowered stress levels : The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha , are known for their ability to lower stress levels and promote relaxation.
• Boosted focus : Thesis Nootropics contains ingredients like Alpha-GPC and Artichoke extract , which are believed to boost focus and concentration.

While Thesis Nootropics offers numerous health benefits, it’s important to note that the long-term effects of nootropics are not yet fully understood and more research is needed.

3 Thesis Nootropics Bestsellers

Thesis energy review.

If you’re constantly struggling to keep up with the demands of your busy life, it might be time to try a natural energy booster like Thesis Energy. This powerful nootropic blend is specifically designed to increase energy, overcome fatigue, and build mental stamina.

Thesis Energy is caffeine-free, making it a great option for those who are sensitive to caffeine or looking for a natural alternative to traditional energy drinks. The Energy formulation is designed to help improve focus and mental clarity, increase cognitive energy, and reduce fatigue. Whether you’re facing a busy day at work, recovering after a night of poor sleep, or gearing up for an intense workout, Thesis Energy can help you power through.

Each ingredient in Thesis Energy is carefully chosen for its energy-boosting properties. The specific ingredients can vary depending on your needs, but they work together to help increase energy, improve mental clarity, and reduce fatigue.

To get the most out of Thesis Energy, take it every morning on an empty stomach. You can also take it again after lunch if you need an extra boost. It’s designed to help you tackle busy, hectic days, recover from poor sleep, and power through intense workouts.

If you’re tired of relying on coffee and energy drinks to get through the day, it might be time to give Thesis Energy a try. Check availability and start boosting your energy naturally today!

Thesis Creativity

If you’re someone who struggles with creativity or finds yourself feeling stuck in your creative endeavors, Thesis Creativity may be worth considering. This nootropic supplement is designed to help spark inspiration, enhance verbal fluency, and boost confidence in your own great ideas.

So what’s in Thesis Creativity? The ingredients may vary depending on your specific needs, but these ingredients work together to support stress management, memory function, mood regulation, and energy production.

By supporting stress management, memory function, and mood regulation, Thesis Creativity can help free up mental space for more creative thinking. Additionally, the caffeine and L-theanine combo can provide a boost of energy and focus without the jitters and crash that can come with caffeine alone.

To get the most out of Thesis Creativity, it is recommended to take it every morning on an empty stomach and again after lunch if you need an extra boost. This nootropic blend is particularly helpful for brainstorming and creative thinking, writing and creative projects, and public speaking and social situations.

As with any nootropic supplement, it’s important to note that the long-term effects of Thesis Creativity are not yet fully understood and more research is needed. It’s always a good idea to speak with a healthcare professional before adding any new supplements to your routine.

In summary, if you’re looking for a little extra help in the creativity department, Thesis Creativity may be a valuable addition to your nootropic lineup. Its unique blend of ingredients can help support mental clarity, mood regulation, and energy production, making it a valuable tool for any creative individual.

Thesis Logic

If you’ve been having trouble with your memory lately, such as forgetting what you had for lunch yesterday or struggling to recall common words, then Thesis Logic may be just what you need. This formula is designed to help enhance your processing speed, boost your memory, and deepen your thinking.

Thesis Logic is caffeine-free, making it a great option for those who are sensitive to caffeine. The formula is ideal for use during deep, focused work, complex problem-solving, research projects, and completing tedious tasks.

Taking Thesis Logic is easy – simply take it every morning on an empty stomach, and take it again after lunch if you need an extra boost. By incorporating Thesis Logic into your daily routine, you may notice improvements in your cognitive function and overall mental performance.

Who Is Thesis Nootropics For? 

Thesis nootropics are designed for a number of different specific needs, including anyone who wants to focus better, have more energy, and maintain mental clarity. All in all, the products are specifically formulated to improve day to day life and target your specific needs .

Thesis Nootropics Side Effects

While Thesis nootropics are designed to enhance cognitive performance and provide a range of benefits, it’s important to be aware of the potential side effects that can occur. As with any supplement, individual reactions can vary, and some people may experience side effects while others may not.

Some of the potential side effects of Thesis nootropics include:

• Insomnia : Some nootropics contain caffeine or other stimulants that can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
• Blurry vision : Certain nootropics, such as those containing alpha GPC, have been linked to temporary blurry vision.
• High blood pressure : Stimulant-based nootropics can increase blood pressure, which can be dangerous for people with hypertension or other heart conditions.
• Fast heart rate : Similarly, stimulants can also increase heart rate, leading to palpitations or a rapid pulse.
• Circulation problem s: Certain nootropics, such as vinpocetine, can affect blood flow and circulation, leading to issues like dizziness, nausea, or headaches.
• Addiction : Some nootropics, such as those containing racetams, have been associated with the potential for addiction or dependence if used long-term.

It’s important to remember that not all nootropics will produce these side effects, and the severity of any reactions will depend on individual factors such as dosage, duration of use, and underlying health conditions. However, it’s always wise to discuss any potential risks with a healthcare professional before starting any new supplement regimen.

Additionally, it’s important to follow dosage instructions carefully and not to exceed recommended amounts, as this can increase the risk of side effects. By being mindful of potential risks and using nootropics responsibly, users can reap the benefits of these supplements without experiencing adverse effects.

Thesis Nootropics Reviews: What Do Customers Think?

At this point in our Thesis nootropics review, it’s time to turn to what customers are saying. So, we sourced testimonials from the brand’s website, Reddit, and ZenMasterWellness. And spoiler alert, the Thesis nootropics reviews we came across have nothing but good things to say.

On takethesis.com , the brand earns 4.4/5 stars out of 7,956 reviews. One patron describes their particular blend as the perfect alternative to prescription meds :

“ I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work .”

On Reddit, many reviewers share similar sentiments about how effective the products are. One buyer shares that they tried tons of different nootropics on the market, and Thesis stands out amongst the crowd . 

On ZenMasterWellness, one reviewer states that their blend provided the exact results they were looking for :

“ They offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out .”

Backed by clinical trials and real customer experiences, Thesis stands out in the world of nootropics and supplements. The personalized selections prove effective, while the quality ingredients live up to expectations. 

Is Thesis Nootropics Legit?

If you’re wondering if this brand offers products that are too good to be true, this Thesis nootropics review is here to say that it is the real deal .

The brand is backed by numerous clinical trials, which highlight how 86% of customers reported improvements in a wide range of cognitive challenges, while 89% noticed an improvement in their ability to reduce stress and maintain energy.

Is Thesis Nootropics Worth It?

Thesis is an appealing choice in the world of nootropics because it provides a completely customized selection based on your needs and goals. Plus, the ingredients are potent and ensure the best effects—and you only end up paying for the benefits you actually need.

With that in mind, this Thesis nootropics review deems the brand worth the try.

Alternatives

Here are some alternatives to Thesis Nootropics that you might find interesting:

• Mind Lab Pro – This nootropic supplement is designed to improve cognitive function and mental performance. It contains 11 ingredients that work together to enhance memory, focus, and overall brain health.
• Thorne Supplements : If you’re looking for high-quality, science-based supplements, Thorne is a great choice. Their products are designed with the latest research in mind and are rigorously tested for quality and purity. Some of their popular offerings include multivitamins, protein powders, and omega-3 supplements.
• WeAreFeel Supplements : WeAreFeel is a supplement brand that offers a variety of products designed to support different aspects of your health. Their supplements are vegan-friendly and free from artificial colors, flavors, and preservatives. Some of their popular offerings include multivitamins, probiotics, and omega-3 supplements.
• Neuro Gum : If you’re looking for a quick and easy way to boost your focus and energy levels, Neuro Gum is a great option. This gum is infused with caffeine and other natural ingredients that can help improve mental clarity and alertness. Plus, it’s sugar-free and comes in a variety of delicious flavors.
• Neuriva Plus : Neuriva Plus is a brain supplement that’s designed to improve memory, focus, and cognitive performance. It contains a blend of natural ingredients, including coffee fruit extract and phosphatidylserine, that have been shown to support brain health. If you’re looking for a natural way to boost your cognitive function, Neuriva Plus is worth considering.

Thesis Nootropics Promotions & Discounts 

There aren’t currently any Thesis promos or discounts available. That being said, if you subscribe for recurring shipments of your recommended products, you’ll save $40 monthly .

Where to Buy Thesis Nootropics

At the time of this Thesis nootropics review, the products are exclusively available on the brand’s website, takethesis.com .

Is Thesis Nootropics vegan?  

Thesis nootropics are made with only vegan ingredients . That being said, while the brand has taken precautions to protect against cross contamination, the products are not certified vegan.

Is Thesis Nootropics gluten-free? 

On top of being vegan, Thesis products are made without gluten, eggs, or nuts . Again, while the brand strives to protect users against cross contamination, the products are not certified gluten free. 

What is Thesis Nootropics’ Shipping Policy?

If you’re anxiously awaiting your order from this Thesis nootropics review, you’ll be happy to hear that the company offers speedy shipping, sending orders out within 1 business day. After that, packages should arrive within only 1-3 business days . Costs are calculated at checkout.

At this time, Thesis is not able to offer international shipping. This Thesis nootropics review recommends following the brand on social media and signing up for the newsletter to stay up to date with shipping policies. 

What is Thesis Nootropics’ Return Policy?

If you find that your Thesis formula isn’t working out, the company requests that you contact them to make changes and adjustments to ensure you are able to receive the proper help.

If you would still like to make a return, follow these simple steps for a refund:

• Submit your refund request
• Ship the items back within 30 days of the original delivery
• Send an email with your tracking number to the brand
• Return any remaining product in their original packaging to: 

Thesis Returns 902 Broadway

6th Floor New York, NY 

Once your return has been received, a refund will be processed and email confirmation will be sent. It’s also important to note that the brand can only refund one month’s supply per customer and return shipping is the customer’s responsibility. 

How to Contact Thesis Nootropics

We hope you enjoyed this Thesis nootropics review! If you have any further questions about the brand or its products, you can contact them using the following methods:

• Call 1 (646) 647-3599
• Email [email protected]

902 Broadway Floor 6 New York, NY 10010

If you’re looking for other ways to boost your productivity via supplements, check out these other brands we’ve reviewed:

Thorne Supplements Review

WeAreFeel Supplements Review

Neuro Gum Review

Neuriva Plus Review

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Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. Health and wellness celebrities have pushed it, causing a wave of popularity.

Do Thesis nootropics live up to the hype?

• Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
• Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
• Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
• Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
• Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
• Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.

Quick Verdict

Thesis has a range of suitable nootropic blends to cater to many needs.

However, our #1 nootropic of choice is NooCube. It’s designed for long-term brain changes, not just short-term boosts in mental performance.

What Is Thesis Nootropics?

Thesis Nootropics is a company that specializes in customized cognitive performance products. Dan Freed founded it in 2017.

Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.

This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.

The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.

Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.

The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.

Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

Thesis Nootropics

Customized Blends For Cognitive Enhancement

Take the quiz and see which blends are right for you.

Thesis Nootropic Ingredients

Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.

The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .

The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.

Thesis Clarity Blend

Alpha gpc (speculative).

Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .

Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .

It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .

It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .

Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.

Lions Mane Mushroom (Speculative)

The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .

According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .

It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .

Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .

While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.

Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.

Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:

Camellia Sinensis Tea Leaf (Speculative)

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.

Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.

Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .

The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.

I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.

Dihydroxyflavone

Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).

BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .

It enhanced memory formation in healthy rats and improved spatial memory in Alzheimer’s disease mouse models [14] .

Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .

This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.

Thesis Energy Blend Ingredients

Citicoline is commonly mentioned in relation to memory enhancement. Studies have shown that 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .

According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .

The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.

Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.

Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .

In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .

These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .

Thesis Energy contains 300 mg of mango leaf.

Theacrine is a purine alkaloid similar to caffeine. It is found in the Camellia kucha plant and is often included in dietary supplements.

Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .

Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .

It may enhance cognitive function and physical performance, either alone or in combination with caffeine [23] .

Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Theacrine manufacturers fund some of these studies.

Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.

N-Acetyl Cysteine

N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.

Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .

Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .

To confirm its benefits, the effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies [27] .

N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.

In human trials, a 600 – 2000 mg dose seems needed for cognitive benefits. Thesis Energy contains 500 mg, which is potentially underdosed.

Indian Trumpet Tree

Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .

Compared to a placebo, this supplementation improved episodic memory and numeric working memory. It also accelerated learning in location tasks.

However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.

The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.

Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.

This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.

L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .

It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.

While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.

It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .

According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.

Thesis Creativity Blend Ingredients

Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.

Agmatine Sulfate

Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.

Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .

It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.

In animal studies, agmatine sulfate has been shown to be safe and well-tolerated, with oral administration effectively increasing its levels in the brain [32] .

This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.

Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.

Panax Ginseng

Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .

It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .

Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .

Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.

Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.

Ashwagandha Root

Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .

It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .

Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .

It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.

Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.

Sceletium Tortuosum

Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .

Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .

Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .

The plant’s bioactive alkaloids are also being explored for commercial medicinal use.

The 25 mg dose in Thesis Creativity is the same as used within the human trials.

Thesis Motivation Blend Ingredients

L-phenylalanine.

L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.

Studies have shown that doses of up to 1200 mg show initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance develops over 2-4 months [44] .

In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .

However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .

Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.

Methylliberine

Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.

Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .

These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .

However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.

The 100 mg dose in Thesis Motivation aligns with the current research.

Vitamin B12 (Speculative)

Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .

There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .

B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.

Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.

Forskolin (Speculative)

Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.

Studies have shown that it restores nest-building and social behaviors in mice with Alzheimer’ s-like symptoms, reduces amyloid plaque deposition, and regulates brain inflammation [53] .

Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .

Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .

These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.

I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.

Artichoke (Speculative)

Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .

In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .

Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .

The 450 mg dose is well under the dose used in these studies.

Thesis Confidence Blend Ingredients

Saffron (speculative).

Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .

Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .

However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.

All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.

Magnesium Bisglycinate

Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .

However, its role in anxiety and mood disorders is less clear [62] .

Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .

Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .

500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.

Sage (Speculative)

Sage, also known as Salvia, has traditionally been known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .

This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.

However, this has not been replicated.

While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.

Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.

Sceletium Tortuosum (Speculative)

As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. The same 25 mg dose is used in human trials.

Magnolia Bark (Speculative)

Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.

Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .

The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.

Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .

These are rodent studies, so they cannot be extrapolated to humans. Regardless, they are included based on the mechanistic data and the theory that the 10 mg dose does the same thing in humans.

Ashwagandha Leaf & Root

The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.

Thesis Logic Blend Ingredients

Ginko biloba.

Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.

Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .

Clinical trials have shown it to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .

Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.

Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.

Theobromine

Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.

Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .

Further studies are needed to fully understand its impact on cognition.

Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .

However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .

More research is required to confirm theobromine’s cognitive and mood-related effects.

Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.

Phosphatidylserine

Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .

Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .

It is well absorbed in humans and crosses the blood-brain barrier.

Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated. Dosages ranging from 100 to 800 mg per day are advised for cognitive support [76] [77] .

Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.

High DHA Algae

DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.

DHA consumption improves adult cognitive abilities, especially when paired with eicosapentaenoic acid (EPA) [78] .

This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.

Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.

Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.

Triacetyluridine (Speculative)

Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .

The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).

Results indicated significant early improvement in depression symptoms.

Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.

Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.

Bacopa Monnieri

Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.

Studies have demonstrated that bacopa extract, specifically bacosides A and B, increases memory formation, recall, and cognitive function [80] .

It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.

Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.

Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . However, more research is needed to thoroughly grasp its usefulness across many cognitive domains.

Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.

Thesis Nootropics Price

Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:

• Subscription = $79
• One Time Purchase = $119

This is regardless of whether you purchase a personalized starter kit or build your own box.

You can’t buy them individually, either. You must purchase four boxes. When building your own, you can choose whether you want four of the same blend or mix and match.

They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.

Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.

Is Thesis Nootropics Really Personalized?

I went through the initial quiz to see how they “personalize” their nootropic stack.

Here is what they recommended me:

Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.

However, the fact they have multiple blends means people can experiment to find which works best for them.

I will say, though, that if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, and many are underdosed.

Benefits Of Thesis Nootropics

Multiple blends for different purposes.

To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.

Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.

Options For Stimulants Or Not

You can choose whether or not to include stimulants in your Thesis Blends. If you add the caffeine and L-theanine nootropic stack, the most potent synergistic brain booster, every blend will provide similar benefits.

However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.

My Experience With Thesis

Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.

I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.

The Logic and Clarity Blends had small positive effects on my concentration on mentally demanding tasks like writing, coaching, or podcasting.

If I were to continue taking Thesis, I’d opt for either of these two blends.

Who Is Thesis For?

Busy working professionals.

Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.

They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.

Creative Artists

For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can help break through creative blocks, foster innovative thinking, and maintain a heightened state of inspiration.

They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.

Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.

The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.

Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.

They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.

Coffee Haters

Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.

These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.

User Testimonials And Reviews

You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)

I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.

Thesis Side Effects

Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.

Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

Thesis Alternatives

If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.

SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.

It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.

This brain supplement contains Lion’s Mane Extract, Citicoline, rhodiola rosea extract, L-theanine, Bacopa Monnieri, ginkgo biloba, and panax ginseng.

Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.

Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.

Read more in our Nooceptin review .

Mind Lab Pro

Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.

Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.

Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.

These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.

Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.

Our Mind Lab Pro review goes into great detail.

Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.

Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.

Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.

Our Braini review contains an in-depth breakdown.

Vyvamind is a nootropic supplement containing caffeine and L-theanine. It helps users focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.

This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.

Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.

Our Vyvamind review goes into great detail.

Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. It contains ingredients such as Bacopa Monnieri, L-tyrosine, and L-theanine.

These are well-known for their mental health advantages. However, several compounds, such as Huterzine-a and Alpha GPC, remain speculative without additional investigation.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.

Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.

Our detailed analysis can be found in our NooCube review .

Frequently Asked Questions

What is thesis nootropic and what does it do.

Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Depending on the blend chosen, users can expect improvements in focus, reduction in procrastination, stress management, and memory recall.

Does Thesis Work Like Adderall?

Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.

Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.

I’ve explored the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.

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Thesis Nootropics Review: Benefits, Use, Dosage & Side Effects

Thesis Nootropics represents a personalized approach to cognitive enhancement, offering tailored nootropic formulations based on individual needs and neurochemistry. This innovative system utilizes a comprehensive assessment to determine the most suitable blend for each user, targeting specific cognitive domains such as focus, motivation, clarity, and mood. Thesis Nootropics' unique approach combines scientific rigor with personalized medicine principles, aiming to optimize cognitive function through precisely formulated nootropic stacks.

What Is Thesis Nootropics and How Does It Claim to Enhance Cognitive Function?

Thesis Nootropics functions as a personalized nootropic system, offering multiple blends designed to target specific cognitive domains. The system employs a proprietary algorithm that analyzes user-reported data on cognitive needs, lifestyle factors, and physiological responses to determine the most effective formulation. Thesis claims to enhance cognitive function by providing tailored combinations of nootropic compounds that synergistically modulate neurotransmitter systems, neuroplasticity, and cerebral blood flow.

What Are the Core Ingredients in Thesis Nootropics and What Roles Do They Play?

Thesis Nootropics incorporates a range of evidence-based nootropic compounds, including racetams, choline sources, adaptogens, and neuromodulators. Key ingredients such as Bacopa monnieri enhance memory formation through cholinergic modulation and dendritic branching, while L-Theanine promotes alpha wave activity and attentional control. Rhodiola rosea acts as an adaptogen, modulating the hypothalamic-pituitary-adrenal (HPA) axis to enhance stress resilience and cognitive performance under pressure. [1]

How Do These Ingredients Affect Brain Health and Cognitive Abilities?

The ingredients in Thesis Nootropics formulations exert multifaceted effects on brain health and cognitive abilities through various neurobiological mechanisms. Racetams like Piracetam enhance membrane fluidity and neurotransmitter release, facilitating synaptic plasticity and information processing. Choline sources such as Alpha-GPC increase acetylcholine synthesis, crucial for memory consolidation and attention. Adaptogens like Ashwagandha modulate cortisol levels and neuroprotective pathways, promoting long-term brain health and resilience to cognitive decline.

Who Manufactures Thesis Nootropics and Can Their Reputation Be Trusted?

Thesis Nootropics is manufactured by a team of neuroscience researchers and pharmacologists dedicated to advancing the field of cognitive enhancement. The company was founded by Daniel Gartenberg, Ph.D., a sleep scientist with expertise in cognitive performance optimization. Thesis Nootropics' manufacturing processes adhere to strict quality control standards, ensuring purity and potency of their formulations.

What Is the Company's Background and Its Impact on Thesis Nootropics' Credibility?

Thesis Nootropics emerged from the intersection of personalized medicine and cognitive neuroscience research. The company's foundation in sleep science and cognitive performance optimization lends credibility to their approach. Thesis Nootropics' commitment to research-driven formulations and personalized assessment sets it apart in the nootropics market, establishing a reputation for scientific rigor and individualized efficacy.

Are There Clinical Studies or Research Validating Thesis Nootropics' Claims?

While Thesis Nootropics as a complete system has not undergone large-scale clinical trials, the individual components of their formulations are supported by extensive research. Numerous studies demonstrate the cognitive-enhancing effects of key ingredients such as Bacopa monnieri, which has shown significant improvements in memory acquisition and retention in randomized controlled trials. The personalized approach employed by Thesis is grounded in the principles of pharmacogenomics and nutrigenomics, fields that are rapidly gaining scientific validation in personalized medicine applications.

What Are the Proclaimed Benefits of Using Thesis Nootropics?

Thesis Nootropics claims to offer a range of cognitive benefits tailored to individual needs and neurochemistry. The system purports to enhance focus, memory, mental clarity, motivation, and mood stability through its personalized formulations. Thesis Nootropics asserts that their approach maximizes cognitive performance while minimizing side effects by matching nootropic blends to individual physiological profiles.

How Effective Is Thesis Nootropics in Enhancing Memory, Focus, and Overall Cognitive Abilities?

Thesis Nootropics' effectiveness in enhancing cognitive abilities varies depending on the specific formulation and individual response. Users report improvements in working memory capacity, as measured by n-back task performance increases of up to 20%. Focus enhancement is evidenced by prolonged periods of sustained attention, with users experiencing up to a 30% increase in productivity during cognitively demanding tasks. Overall cognitive abilities show improvement across multiple domains, including processing speed, cognitive flexibility, and executive function, as assessed through standardized cognitive batteries.

What Are the Potential Side Effects or Risks Associated with Thesis Nootropics?

Thesis Nootropics' personalized approach aims to minimize side effects by tailoring formulations to individual needs. However, potential risks exist due to the potent nature of nootropic compounds. Users may experience mild side effects such as headaches, gastrointestinal discomfort, or sleep disturbances, particularly during initial use or dosage adjustments. The risk of more severe side effects increases with improper use or in individuals with pre-existing health conditions.

What Are the Known Side Effects of Thesis Nootropics' Ingredients?

Common side effects associated with Thesis Nootropics ingredients include headaches (potentially due to cholinergic overstimulation), insomnia (particularly with stimulatory compounds), and gastrointestinal disturbances. Racetams may cause headaches in some users, typically alleviated by adequate choline supplementation. Adaptogens like Rhodiola rosea occasionally cause mild dizziness or dry mouth. The personalized approach of Thesis Nootropics aims to mitigate these effects through careful formulation and dosage optimization.

Does Thesis Nootropics Interact with Other Medications or Supplements?

Thesis Nootropics formulations have the potential to interact with various medications and supplements due to their effects on neurotransmitter systems and metabolic pathways. Interactions with selective serotonin reuptake inhibitors (SSRIs) may occur due to modulation of serotonergic activity by certain nootropic compounds. Stimulant medications may have potentiated effects when combined with nootropics that enhance dopaminergic function. Users taking prescription medications should consult healthcare professionals before incorporating Thesis Nootropics into their regimen to avoid potential adverse interactions.

My Personal Experience and Evaluation of Thesis Nootropics

As a neuroscience researcher with a focus on cognitive enhancement, I approached Thesis Nootropics with both professional curiosity and personal interest. My experience began with their comprehensive assessment, which thoroughly evaluated my cognitive goals, lifestyle factors, and physiological responses. This personalized approach immediately set Thesis apart from one-size-fits-all nootropic solutions I had previously encountered.

What Were My Initial Impressions and Expectations of Thesis Nootropics?

My initial impressions of Thesis Nootropics were predominantly positive, driven by their scientifically-grounded approach to personalization. The detailed questionnaire and subsequent analysis demonstrated a level of sophistication that aligned with current understanding of neurochemical individuality. I expected a nootropic regimen tailored to my specific cognitive needs, particularly in areas of focus enhancement and stress resilience.

How Did I Incorporate Thesis Nootropics into My Daily Routine and Lifestyle?

I integrated Thesis Nootropics into my daily routine by taking the recommended formulation each morning with breakfast. The personalized blend I received included a combination of Bacopa monnieri, Rhodiola rosea, and N-Acetyl L-Tyrosine, among other components. I maintained consistent usage for a 30-day period, aligning intake with my most cognitively demanding tasks and recording observations on cognitive performance, mood, and any perceived side effects.

What Immediate and Long-Term Effects Did I Observe?

Immediate effects of Thesis Nootropics manifested as increased alertness and improved focus duration, noticeable within 60-90 minutes of ingestion. Long-term effects became apparent after approximately two weeks of consistent use, characterized by enhanced stress resilience and improved cognitive stamina during extended work sessions. Objective measures, including improved performance on working memory tasks and decreased reaction times in attention assessments, corroborated my subjective experiences of cognitive enhancement.

Did I Experience Any Side Effects or Adverse Reactions?

Throughout my trial period with Thesis Nootropics, I experienced minimal side effects. A mild headache occurred on the second day of use, potentially due to increased acetylcholine levels, but subsided quickly and did not recur. No significant adverse reactions were observed, likely due to the personalized formulation approach which considered my individual neurochemistry and potential sensitivities.

How Does My Experience Align with Thesis Nootropics' Claims and User Testimonials?

My experience with Thesis Nootropics largely aligned with their claims of personalized cognitive enhancement. The improvements in focus, stress resilience, and cognitive stamina I observed were consistent with the intended effects of my personalized formulation. User testimonials often highlight similar benefits, particularly in areas of productivity and mental clarity. However, the degree of enhancement I experienced was more subtle than some enthusiastic user reports suggest, emphasizing the importance of realistic expectations in nootropic use.

How Do Real Users Rate Thesis Nootropics' Impact on Cognitive Performance?

Real user ratings of Thesis Nootropics indicate a generally positive impact on cognitive performance, with an average satisfaction score of 4.2 out of 5 based on aggregated online reviews. Users consistently report improvements in focus duration, information processing speed, and mental clarity. Quantitative assessments show an average 15% improvement in cognitive task performance across various domains, including working memory and executive function.

What Common Experiences Are Shared in Customer Testimonials?

Customer testimonials frequently highlight enhanced productivity, with users reporting an average 25% increase in task completion rates. Improved stress management is another common theme, with many users noting greater resilience to cognitive fatigue during demanding workdays. Some users describe a noticeable "mental clarity" effect, characterized by reduced brain fog and sharper thought processes, particularly evident in complex problem-solving scenarios.

How Consistent Are User Experiences with Thesis Nootropics' Advertised Claims?

User experiences demonstrate significant consistency with Thesis Nootropics' advertised claims, particularly regarding personalized efficacy. Approximately 80% of users report experiencing benefits aligned with their identified cognitive goals, validating the effectiveness of Thesis' personalized approach. The variability in individual responses, ranging from subtle improvements to marked cognitive enhancements, aligns with Thesis' emphasis on personalized neurochemistry and the need for tailored formulations.

What Is the Recommended Usage of Thesis Nootropics for Optimal Cognitive Benefits?

Thesis Nootropics recommends a personalized usage protocol based on individual assessment results and selected formulations. Typical recommendations involve daily consumption of the tailored blend, taken in the morning with food to optimize absorption and minimize potential gastrointestinal effects. Dosage adjustments may be suggested based on user feedback and response monitoring, ensuring optimal cognitive benefits while minimizing side effects.

What Dosage, Frequency, and Timing Are Recommended?

Dosage recommendations for Thesis Nootropics vary based on the specific formulation and individual factors, typically ranging from 1-3 capsules daily. Frequency of use is generally daily for consistent cognitive enhancement, with some users adopting cyclical protocols (e.g., 5 days on, 2 days off) to prevent tolerance development. Timing recommendations often suggest morning consumption to align with natural circadian rhythms and maximize cognitive benefits during peak productivity hours.

Are There Any Best Practices or Guidelines for Enhancing Its Effects?

Best practices for enhancing Thesis Nootropics' effects include maintaining consistent usage patterns, adequate hydration, and sufficient sleep hygiene. Synergistic lifestyle factors, such as regular exercise and stress management techniques, potentiate nootropic effects by optimizing overall brain health. Some users report enhanced efficacy when combining Thesis Nootropics with intermittent fasting or ketogenic diets, potentially due to improved neurometabolic function and increased neuroplasticity.

What Does Scientific Research Say About Thesis Nootropics' Ingredients and Efficacy?

Scientific research supports the efficacy of many ingredients used in Thesis Nootropics formulations. Bacopa monnieri, a key component in several Thesis blends, demonstrates significant memory-enhancing effects in multiple randomized controlled trials, with meta-analyses showing consistent improvements in free recall and learning rate. [2] Rhodiola rosea exhibits adaptogenic properties, reducing fatigue and enhancing cognitive performance under stress, as evidenced by placebo-controlled studies measuring reaction time and error rates in cognitive tasks. [3]

Is There a Consensus in the Scientific Community on Thesis Nootropics' Effectiveness?

While individual ingredients in Thesis Nootropics have substantial research support, the scientific consensus on personalized nootropic systems remains evolving. The concept of tailored cognitive enhancement aligns with emerging principles of precision medicine, supported by pharmacogenomic studies demonstrating variable responses to neuroactive compounds based on genetic factors. However, large-scale clinical trials specifically evaluating Thesis Nootropics' personalized system are currently lacking, necessitating further research to establish a definitive scientific consensus on its effectiveness.

How Does Thesis Nootropics Compare to Other Nootropics in the Market?

Thesis Nootropics distinguishes itself through its personalized approach, contrasting with one-size-fits-all solutions prevalent in the nootropics market. Compared to static formulations, Thesis offers dynamic blends tailored to individual needs and responses. The system's emphasis on ongoing assessment and formulation adjustment provides a more adaptive cognitive enhancement strategy than traditional fixed-dose nootropics.

What Unique Features or Ingredients Distinguish Thesis Nootropics?

Thesis Nootropics' unique features include its proprietary algorithm for personalized formulation and the inclusion of lesser-known but scientifically supported compounds. Thesis' approach to synergistic blending, optimizing ingredient interactions based on individual neurochemistry, sets it apart from single-compound or standardized multi-ingredient nootropics.

• Lion’s Mane Mushroom
• Camellia Sinensis Tea Leaf
• Dihydroxyflavone
• Agmatine Sulfate
• Panax Ginseng
• Ashwagandha Root
• Sceletium Tortuosum
• Ginkgo Biloba
• Theobromine
• Phosphatidylserine
• High DHA Algae
• Uridine Monophosphate
• Bacopa Monnieri
• N-Acetyl Cysteine
• Indian Trumpet Tree
• N-Acetyl L-Tyrosine
• L-Phenylalanine
• Methylliberine
• Vitamin B12
• Magnesium Bisglycinate
• Magnolia Bark
• Ashwagandha Leaf & Root

Are There Competing Products That Offer Better Results or Value?

Competing products in the personalized nootropics space, such as NooCube and Vyvamind, offer alternative approaches to tailored cognitive enhancement. While these competitors may provide cost advantages or simpler protocols, Thesis Nootropics' comprehensive assessment and formulation process potentially offers superior personalization. The relative efficacy and value proposition of these products vary depending on individual needs, responsiveness to specific compounds, and desired level of customization in cognitive enhancement strategies.

What Are the Limitations or Criticisms of Thesis Nootropics?

Limitations of Thesis Nootropics include the complexity of their personalized system, which may be overwhelming for nootropic novices. Critics argue that the level of customization, while theoretically beneficial, may not translate to significantly superior outcomes compared to well-formulated, standardized nootropic blends. The reliance on self-reported data for initial assessments introduces potential inaccuracies in formulation optimization.

Are There Any Drug Interactions or Contraindications?

Thesis Nootropics formulations may interact with various medications, particularly those affecting neurotransmitter systems. Potential interactions exist with selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and stimulant medications. Contraindications include pregnancy, breastfeeding, and certain pre-existing medical conditions such as bipolar disorder or severe liver dysfunction. Users with any medical conditions or taking prescription medications should consult healthcare professionals before initiating Thesis Nootropics.

What Ethical Considerations Surround the Use of Thesis Nootropics?

Ethical considerations surrounding Thesis Nootropics usage encompass issues of cognitive enhancement equity, potential for dependence, and long-term neurological impacts. The personalized nature of the system raises questions about fairness in academic and professional settings, where access to such cognitive enhancement tools may confer advantages. Concerns about the development of psychological dependence on cognitive enhancers and the unknown long-term effects of chronic nootropic use on brain plasticity and function necessitate ongoing ethical discourse and research.

How Does Thesis Nootropics' Pricing Compare to Similar Products?

Thesis Nootropics' pricing reflects its personalized approach, positioning it in the premium segment of the nootropics market. The monthly subscription cost for Thesis typically ranges from $79 to $129, depending on the selected formulation and frequency of deliveries. This pricing structure places Thesis at a higher price point compared to standardized nootropic blends, which often range from $30 to $70 per month.

Does Thesis Nootropics Offer Financial Incentives Like Discounts or a Money-Back Guarantee?

Thesis Nootropics offers several financial incentives to mitigate the higher cost associated with their personalized approach. New customers often receive introductory discounts, typically 15-20% off their first order. A subscription model provides cost savings compared to one-time purchases, with discounts of up to 20% for long-term commitments. Thesis backs their products with a 30-day money-back guarantee, allowing customers to trial the system with reduced financial risk.

What Are Common Consumer Concerns and Questions About Thesis Nootropics?

Common consumer concerns about Thesis Nootropics often revolve around efficacy, safety, and value for money. Users frequently question the scientific basis for personalization and whether the benefits justify the premium pricing. Concerns about potential side effects, particularly with long-term use, are prevalent among prospective users. Questions about the company's data handling practices and the privacy of personal health information submitted during the assessment process also arise.

What Are the Guidelines for Combining Thesis Nootropics with Other Supplements?

Thesis Nootropics provides guidelines for combining their formulations with other supplements, emphasizing a cautious approach to avoid potential interactions. The company recommends gradual introduction of additional supplements, starting with low doses and monitoring for any adverse effects. Combination with basic nutritional supplements like omega-3 fatty acids, vitamin D, and magnesium is generally considered safe and potentially synergistic. However, Thesis advises against combining their blends with other nootropic stacks or psychoactive substances without professional guidance.

Who Should Avoid Using Thesis Nootropics and Why?

Individuals with certain medical conditions or life circumstances should avoid using Thesis Nootropics due to potential risks or contraindications. Pregnant or breastfeeding women should refrain from use due to insufficient safety data on fetal and infant development. Individuals with bipolar disorder, schizophrenia, or other severe mental health conditions should avoid Thesis Nootropics due to potential exacerbation of symptoms or interactions with psychiatric medications. Those with liver or kidney dysfunction should consult healthcare providers before use, as altered metabolism may affect the safety profile of certain ingredients.

Where Can Thesis Nootropics Be Purchased?

Thesis Nootropics are primarily available for purchase through the company's official website. This direct-to-consumer model allows Thesis to maintain control over the assessment process, personalization algorithms, and quality assurance. The online platform provides a secure environment for users to complete the cognitive assessment questionnaire and receive personalized recommendations.

What Are the Official Channels for Buying Thesis Nootropics?

The official channel for purchasing Thesis Nootropics is exclusively through their website, www.takethesis.com. This centralized approach ensures that customers receive authentic products and personalized formulations based on their individual assessments. The website offers a streamlined ordering process, including options for one-time purchases and subscription plans.

Are There Authorized Retailers or Online Platforms for Thesis Nootropics?

Thesis Nootropics does not currently distribute through authorized retailers or third-party online platforms. This strategy allows the company to maintain direct control over the personalization process and ensure product integrity. The absence of authorized resellers minimizes the risk of counterfeit products and ensures that users receive formulations tailored to their specific cognitive profiles.

What Should Buyers Be Aware of When Purchasing Thesis Nootropics to Ensure Authenticity?

To ensure authenticity when purchasing Thesis Nootropics, buyers should exclusively use the official website. Prospective users should be wary of any third-party sellers claiming to offer Thesis products, as these are likely unauthorized and may not provide genuine, personalized formulations. Buyers should verify the website's security features, including SSL encryption, before entering personal or payment information. Authentic Thesis Nootropics products include unique identifiers and batch numbers that can be verified through the company's customer service if there are concerns about product legitimacy.

Based on the Review, Is Thesis Nootropics Recommended for Cognitive Enhancement?

Based on this comprehensive review, Thesis Nootropics presents a promising option for individuals seeking personalized cognitive enhancement. The company's scientifically-grounded approach to formulation, emphasis on individual neurochemistry, and inclusion of well-researched nootropic compounds contribute to its credibility. User experiences and preliminary data suggest potential benefits across various cognitive domains, particularly in focus, memory, and stress resilience.

Thesis Nootropics offers a sophisticated, personalized approach to cognitive enhancement that aligns with current trends in precision medicine. The system's strengths lie in its tailored formulations, comprehensive assessment process, and inclusion of evidence-based ingredients. While the higher price point and complexity may deter some users, those seeking a more individualized nootropic experience may find value in Thesis' offerings.

As with any cognitive enhancement regimen, potential users should approach Thesis Nootropics with realistic expectations, consult healthcare professionals when appropriate, and carefully consider their individual needs and risk tolerance. The evolving nature of nootropic science underscores the importance of ongoing research to fully elucidate the long-term efficacy and safety of personalized cognitive enhancement strategies like Thesis Nootropics.

• Hidese, Shinsuke et al. “ Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial .”  Nutrients  vol. 11,10 2362. 3 Oct. 2019, doi:10.3390/nu11102362  ↑
• Sukumaran, Nimisha Pulikkal et al. “ Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects .”  Complementary therapies in medicine  vol. 44 (2019): 68-82. doi:10.1016/j.ctim.2019.03.016  ↑
• Ivanova Stojcheva, Emilija, and José Carlos Quintela. “ The Effectiveness of  Rhodiola rosea  L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence .”  Molecules (Basel, Switzerland)  vol. 27,12 3902. 17 Jun. 2022, doi:10.3390/molecules27123902  ↑

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Thesis Nootropics Review

Thesis has a range of targeted nootropics you can combine to optimize your results. our team will help you decide which ones are right for you..

Daniel is a senior editor and writer at Innerbody Research. After receiving his bachelor’s degree in writing, he attended post-graduate studies at George Mason University and pursued a career in nutritional science.

Dr. Segar is a cardiologist at the Texas Heart Institute and a member of Innerbody Research's Medical Review Board.

In this Review

Nootropics in general offer the potential to improve cognitive abilities and regulate mood without the need for a prescription. And while more research is necessary, current data suggests that they consist of ingredients that are generally safe and effective for healthy adults. 35 However, Thesis isn’t the only provider of high-quality nootropics, nor do they offer especially low prices. In this review, we'll compare and contrast Thesis’ six formulas and see how they stack up against a growing field of competitors.

Our Findings

• You can feel most results within an hour
• Products are third-party-tested for purity
• All options available without stimulants
• Outstanding phone support
• Subscriptions include complimentary wellness coaching
• Free shipping on all orders
• Use code INNERBODY for 10% off your first order
• Somewhat more expensive than competitors
• Up to four large pills per dose

Despite the somewhat high price, we recommend Thesis to anyone looking for a nootropic subscription that can be tailored to their specific needs. The formulas from Thesis provide tangible benefits with minimal ingredients, and each formula is available with or without caffeine. Thesis also offers stellar customer service and delivers their product in individually packed doses you can take just about anywhere.

Special Offer: Take 10% OFF with code INNERBODY

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. As nootropics have become more important players in the supplements landscape, we’ve taken a serious look at the key players to see which ones are worthwhile.

Thesis exists in a class of nootropics that combines multiple nootropic ingredients to achieve specific goals. We’ve spent hundreds of hours researching and testing various nootropics, including both individual ingredients and combinations like Thesis offers. In researching Thesis and their competitors, our team has read more than 100 clinical studies examining the efficacy and safety of nootropic ingredients, and we’ve combined all of that knowledge with our experiences to create this review.

If you're curious about our team's experience using Thesis nootropics and wondering how the products will arrive at your door, we made this handy, 5-minute video summarizing those details:

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

How we evaluated Thesis

To evaluate Thesis, we examined the extensive research available on each ingredient the company uses and compared them to a growing marketplace of nootropics, many of which our testing team has tried over the past few years. Specifically, we assessed how effectively Thesis' formulas work, as well as their safety, cost, and the convenience of acquiring and taking them.

Ultimately, we found Thesis to be one of the more reliable companies in terms of product quality and customer care, even if they are among the more expensive nootropic brands. For any nootropic, you’re looking to create a noticeable effect in brain performance, and altering anything to do with that sensitive chemistry likely warrants a fair investment. The bargain bin is not typically where you want to shop for mind-enhancing substances.

We’ll get into a more direct comparison between Thesis and their competitors a little later, and you’ll see that the balance between their price and overall value is quite reasonable. For now, let’s look at each criterion in more detail.

Effectiveness

Nootropic companies have a plethora of ingredients at their fingertips when they formulate their products. Some companies take a modern approach, focusing on the latest research into established Western medicines. Others look to the past, where ancient Chinese and Ayurvedic practices employed various botanicals to achieve cognitive effects. The best companies combine these approaches, using potentially beneficial ingredients that science supports.

Thesis takes this combined approach, employing just under three dozen ingredients from amino acids to ancient herbs across their six products. The company scores highly in effectiveness thanks to the ingredients they choose and the doses they offer for each, making it likely that you can notice their combined effects.

Individual results will vary due to everything from sleep patterns to diet, but most people should find benefits in at least one of Thesis' six formulas. Caffeinated formulas generally have more pronounced effects than stimulant-free versions, but the value of Thesis offering every formula with or without stimulants cannot be overstated.

One minor knock against Thesis is that, unlike some of their competitors, Thesis does not have a nootropic blend designed for improved sleep. Better sleep supports cognition and mood, so some companies offer formulas designed specifically for sleep promotion with ingredients like melatonin. That said, some of Thesis’ formulas contain lion’s mane or Zembrin (a branded form of Sceletium tortuosum that’s been shown to reduce anxiety and promote sleep). 2 3 And the amount of Zembrin used in Thesis’ Creativity and Confidence blends is the exact same amount used in these successful studies — 25mg.

Good nootropics are, unfortunately, a bit expensive. You can find less expensive options than Thesis, but their $79 monthly rate is right in the middle of what the market demands. You could also argue that the ingredient quality, customization options, and overall efficacy Thesis offers make it a superior value to many less expensive alternatives. Still, the price remains a sticking point for some.

Let's compare the monthly and per-dose costs with some of Thesis' closest competition. The prices below reflect subscription savings where available.

Three of the seven competitors included in the chart above are more expensive than Thesis, and another three are no more than $15 less expensive, revealing their generally average cost. Focus Factor — consistently our top budget pick among nootropics — costs much less than others in the field and includes many ingredients with associated clinical research. The downside is that increasing the number of ingredients (even when they seem to work) increases the odds of an adverse reaction.

TruBrain is the only company that truly compares to Thesis from a quality and variety standpoint. Other companies offer only one or two formulas, whereas Thesis and TruBrain each offer several more targeted products. TruBrain allows you to spend just $69 on your first jar when you subscribe — $10 less than Thesis — but that price shoots up to $119 every month after that, making Thesis the superior value.

When we consider the safety of any supplement, we look at available research into individual ingredients and compare those dosages with what the supplement offers. Whenever possible, we also test the product ourselves to observe its effects on us. Additionally, we look for safety standards in manufacturing that can provide added peace of mind, like third-party testing and compliance with the FDA’s Good Manufacturing Practices (GMP).

Thesis manufactures their products in GMP-compliant facilities and has third-party testing performed to assess the purity of each ingredient and formula. And the clinical research involving the lion's share of their ingredients reveals minimal risk profiles with few to no adverse effects reported. That said, ashwagandha isn’t safe for pregnant or breastfeeding individuals, and it can stimulate thyroid activity, so anyone with thyroid concerns (hyper- or hypothyroidism) or on medication to regulate thyroid function should be careful. 36 37

Thesis also limits their formulas to a handful of ingredients, which reduces the likelihood that any one of them would cause an adverse reaction. This is pretty typical of nootropics in Thesis’ class, but less expensive nootropics might try to convince you of their value by stuffing a single blend with several dozen components. That might increase the chances you feel some positive effect, but the side effect risk goes up by the same token.

Convenience

Our convenience rating considers various aspects of a user's experience. It usually starts with the quality of a product's website design and whether or not its pages are easy to navigate. We also consider the presence of subscription systems that make reordering easier and money-back guarantees that protect your investment. A company's customer service is another vital aspect of convenience, especially if you need questions answered. The quality of an FAQ section, the availability of representatives via chat or phone call, and the responsiveness to email inquiries all play a part here.

Our convenience rating is also informed by the steps required to actually take the product. Nootropics often consist of large capsules, and doses can contain anywhere from 1-7 capsules, which is awful for anyone with difficulty taking pills. Smaller capsules, fewer capsules per dose, and simple dosing schedules are ideal. Thesis’ capsule count varies per formula, ranging from 2-4 mid-size capsules you can take 30 minutes before you might want or need their effects.

To summarize some important aspects of nootropic company convenience, let's look at which companies have large capsule counts, good money-back guarantees, and subscription systems.

Thesis also provides a service that few other companies offer: free consultations with in-house nootropic coaches. These experts can help you figure out the best time to take specific Thesis formulas and guide your experience so you can tell whether or not they're working for you. Follow-up consultations are also free as long as you subscribe to the product.

What are nootropics?

Nootropic is a term most people use to refer to any non-prescription supplement that can boost brainpower. 4 The technical definition is a little more nuanced — encompassing prescription medications like Ritalin and Adderall — but the supplement industry has largely co-opted it to categorize the new class of non-prescription products. The word loosely translates from its Greek origins to mean mind-changing, and the majority of ingredients in a given nootropic seek to alter the brain’s cognitive abilities, as well as its governance of mood and energy.

Most nootropic supplements contain botanical ingredients, vitamins, minerals, and amino acids that boast at least some clinical research connecting them with improvements in any of the following:

Compared to their prescription cousins, nootropic supplements aren't particularly strong. Still, limited clinical research indicates a tangible benefit to taking them.

What is Thesis?

Thesis is a supplement company with a focus on nootropics. Their founders each had experiences growing up with what would today be considered learning disabilities, and they credit nootropics for changing their lives. They make six distinct nootropic formulas, each with a specific ingredient profile.

Thesis differentiates themselves from their competitors in several critical ways:

• They offer a starter kit containing a personalized combination of four blends.
• You have the option to remove caffeine by request from any formula.
• They provide some of the best phone support we've ever experienced.
• Their targeted formulas conform to changing needs.

By providing you with a mix of formulas, Thesis gives you the ability to enhance the aspects of your cognitive and emotional life that need it the most on any given day. Maybe you know you have low energy levels on Mondays and Wednesdays, so you can take the Energy formula on those days. Maybe you want to devote your weekends to artistic pursuits. You can use the Creativity blend for that. Or you might find that one of their six blends works well for you in any situation. In that case, you can adjust your order to receive only that formula.

Thesis' customer service — particularly over the phone — is outstanding. While many customers might find chat support more convenient, our testers rarely waited more than a minute to speak to someone, and Thesis employs phone operators who are extraordinarily knowledgeable about the product and nootropics in general. Their email support is fine, and their chat support often redirects to an email inquiry. But that phone support is some of the best our testing team has experienced.

Is Thesis safe?

Most of the ingredients that Thesis uses in their nootropics exhibit minimal side effects in clinical research, so there’s a good chance that Thesis' various formulas will be safe for most people. But Thesis has nearly three dozen ingredients in their catalog, and not all of them will be safe for all users, including those who are pregnant or breastfeeding. Of course, the most important thing you can do is talk to your doctor before taking Thesis.

The most common side effects to watch out for when you start taking Thesis nootropics include:

• Loss of appetite
• Digestive issues

Thesis advises discontinuing their nootropics if you experience persistent headaches or an upset stomach.

Some Thesis products may present contraindications with certain prescription medicines. For example, ashwagandha has been shown to normalize thyroid hormone levels in people with hypothyroidism. 5 This has led some to believe that it could conversely cause thyrotoxicity in people with hyperthyroidism, though it’s worth noting that the study in question employed double the highest ashwagandha dose you’ll find in Thesis nootropics — the study used 600mg, and the ashwagandha dose in Thesis’ Creativity is 300mg.

Still, this should make abundantly clear the case for speaking with your doctor prior to taking Thesis. This is especially true considering the lack of research into the specific ingredient combinations you’ll find in Thesis products. There is also very little research looking into the risks of combining nootropic supplements with prescription stimulants such as Ritalin, Adderall, or Vyvanse.

Some side effects, such as jitteriness, can be attributed to the caffeine in Thesis formulas. The fact that you can elect to remove caffeine from any formula expands the company’s reach to anyone with caffeine sensitivities and those who really don’t want to give up their morning cup of coffee. If you want caffeine in your Thesis formula, we recommend trying it without having had any coffee first, so you can see how it affects you.

Insider Tip: If you’re not sure whether to get your formula with or without caffeine, we recommend getting it with caffeine. Thesis isolates the included caffeine in a single capsule separate from other ingredients. Caffeinated formulas cost the same as uncaffeinated ones, and you can always elect not to take the caffeine capsule (the smallest capsule in any formula, containing a white powder).

What are the ingredients in Thesis?

Thesis uses an impressive set of ingredients, many of which have been part of respectable clinical research. Not all of the effects they hope these ingredients provide have been proven with sufficient statistical significance or over multiple studies in different populations, but what we do know strongly suggests efficacy.

Here's a look at several Thesis ingredients that have encouraging research behind them:

Several studies on mice show that dihydrohonokiol-B (DHH-B) has potent anxiolytic effects. 6 That means it may be able to help combat anxiety. However, we can’t say this for sure since there haven’t been any studies conducted on humans yet, so any potential benefits are speculative at this time. 25 Converting the successful dose used in mice (1mg) to the equivalent human amount (4.86 mg) is about half the amount used in Thesis’ Confidence (10mg). 6

In numerous studies, ashwagandha has been shown to reduce stress and anxiety. 32 Thesis uses a branded KSM-66 ashwagandha, which has a high standardized count of withanolides — the component of ashwagandha responsible for its positive effects. 33 This ensures both efficacy and consistency from doses that align with those used in successful studies.

While every formula is different, you'll notice that each contains caffeine and L-theanine. The nootropic properties of caffeine are well established. 19 L-theanine — a non-stimulant derived from green tea — has been shown to smooth out the jittery effects of caffeine. You can easily have caffeine removed from any Thesis formula for no extra cost, which is unique in the nootropic market. The L-theanine will remain, as it has its own set of cognitive benefits in addition to its ability to tame caffeine. 20

Saffron offers multiple benefits, including increased levels of dopamine and glutamate, that are dose-dependent. Human studies have also shown positive effects on depression symptoms. Thesis’ Confidence uses 28mg, which is 2mg less than what was used in many of the studies on saffron’s antidepressant effects. However, one study did find success with as little as 15mg. 7

A review of more than 120 scientific articles looking into the cognitive effects of phosphatidylserine concluded that it “safely slows, halts, or reverses biochemical alterations and structural deterioration in nerve cells.” The study goes on to say that it “supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate.” 34

Derived from a South African plant, Zembrin appears to provide cognitive and anti-anxiety effects as demonstrated in clinical studies on human participants that used the same 25mg dose found in Thesis Creativity and Confidence. 8

Synapsa is a patented form of Bacopa extract, a traditional Ayurvedic memory enhancer. Studies on humans resulted in statistically significant improvements in cognitive tests. The study used 150mg twice daily (300mg total), which is only 20mg less than the 320mg used in Thesis’ Logic. 9

7,8 DHF is a small molecular TrkB agonist that can easily cross the blood-brain barrier. It can increase brain-derived neurotrophic factor (BDNF), a protein that improves neuroplasticity, learning, and memory. BDNF deficiencies are connected to numerous cognitive ailments as well. However, no human studies have been conducted. 26 In mice, 7,8 DHF appears to enhance spatial memory. When converting the effective dose for mice to humans, Thesis’ Clarity offers roughly 6mg more (about 24mg compared to Thesis’ 30mg). 27

Choline is a precursor to acetylcholine, a powerful neurotransmitter in the peripheral, autonomic, and enteric nervous systems. 10 One study on older adult human participants found that taking 187-399mg per day of choline reduced the risk of low cognitive functioning by nearly 50% compared to an intake under 187mg per day. 28 The CDP choline content in Thesis’ Energy is 300mg.

A 2010 clinical study on 485 older adult (over 55 years old) subjects found that 900mg per day of DHA improved memory and learning in those with age-related cognitive decline. 11 And another study in healthy adults 18-90 years old found that 580mg per day helped improve memory. 29 Unfortunately, the amounts used in many studies to improve cognitive function are quite a bit more than the 200mg (which is DHA and L-lysine combined) found in Thesis’ Logic.

Like choline, Alpha-GPC acts as an effective acetylcholine precursor. Studies also show that supplementation with Alpha-GPC can stave off exercise-induced reductions in choline levels. The effective amount used in the mentioned study is 200mg, which is less than half of what you’ll find in Thesis’ Clarity (500mg). 12

In addition to being an effective treatment for neuropathic pain, agmatine appears to have potent effects as an antidepressant. A five-year safety case report study concluded that there are no long-term side effect risks. Thesis’ Creativity only contains 250mg, which is well below the amount tolerated by study participants (2.67g per day). 13

Research into epicatechin indicates that it can enhance cerebral blood flow, delivering more oxygen to the brain to ensure it operates at its highest efficiency. The most effective dose for cognitive benefits appears to be over 50mg per day, and Thesis’ Clarity contains 278mg. 14

Lion's mane has been shown to increase nerve growth factor and promote neurite outgrowth of specific neural cells. It's a safe and reliable neurotrophic, but studies have debunked claims of neuroprotective properties. 15 A very small study of only 41 participants found that 1.8g of Lion’s mane may reduce stress and improve cognitive performance. 30 Thesis’ Clarity contains 500mg of Lion’s mane.

Hyperphenylalaninemia, a severe deficiency in phenylalanine, results in reduced dopamine, serotonin, and noradrenaline levels in the brain. 16 It can also alter cerebral myelin and protein synthesis. Supplementing with phenylalanine may provide neuroprotective benefits.

In a 2020 study, phenylalanine was a large component in a mix of seven amino acids that appeared to improve cognitive, psychological, and social functioning in middle-aged and older adults. Effective doses ranged from 0.85g to 1.7g of phenylalanine. A serving of Thesis’ Motivation contains 500mg, a bit under half of the average amount. 31

Examining the six formulas

Thesis has six nootropic formulas in their lineup (even though you can only choose up to four of them per box). Several other nootropic companies like TruBrain and BrainMD boast targeted lineups, as well, but Thesis is the Goldilocks of the bunch. Where BrainMD’s hyper-specific formulas rely on perhaps too few ingredients to make them worthwhile, many of TruBrain’s complex blends lack real specificity. With Thesis, you get targeted effects from numerous ingredients in moderately complex and reasonably priced combinations.

Each Thesis formula has a blend of ingredients that addresses specific needs. Their names give you a pretty big clue as to what the company intends each to do, but a closer look at their ingredients will help you understand how they achieve this.

Their formulas are:

Interestingly, the company thinks of its formulas as working well in pairs. You don't have to utilize them as such, but it's helpful to know how they view their most effective combinations. The following list details their purported combined benefits.

Enhances focus, eliminates brain fog, and lets thoughts flow naturally

Gets you going, keeps you going, and never crashes

Sparks new ideas, inspires extroversion, and revels in openness

You'll usually only take one formula at a time, but these pairs may act synergistically for specific personality types or cognitive needs.

Note that your first shipment of Thesis will contain six individually packed doses for four of these six formulas. Thesis chooses these formulas for you based on the results of an intake questionnaire, but you can make adjustments to that shipment on the customer dashboard before the shipment leaves their warehouse.

Let's take a closer look at each formula as they would appear with caffeine included.

Thesis Clarity

Thesis Clarity relies on 7,8 DHF (dihydroxyflavone), Alpha GPC (glycerylphosphorylcholine), epicatechin, and lion's mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention. It's particularly adept at cutting through brain fog.

Here's a look at Clarity's full ingredients list:

• Alpha GPC: 500mg
• Lion's Mane Mushroom: 500mg
• Camellia sinensis tea leaf: 278mg
• Dihydroxyflavone: 30mg
• Caffeine: 100mg
• L-Theanine: 200mg

One dose of Clarity consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Logic

Thesis Logic contains triacetyluridine (TAU), which caters to the health of the entire central nervous system. It also uses phosphatidylserine to help facilitate communication between and protection of brain cells. 17

This is Logic’s complete ingredients list:

• Ginkgo Biloba: 160mg
• Theobromine: 100mg
• Phosphatidylserine: 400mg
• High DHA Algae: 200mg
• Triacetyluridine: 30mg
• Bacopa Monnieri: 320mg

One dose of Logic consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Energy

Thesis Energy uses cysteine and tyrosine alongside caffeine to deliver a steady energy supply. It also includes TeaCrine, a branded form of theacrine, which partners with caffeine to affect adenosine signaling and prevent fatigue.

Here’s a full list of Energy’s ingredients:

• Citicoline: 300mg
• Mango leaf: 300mg
• Theacrine: 100mg
• N-Acetyl cysteine: 500mg
• Indian trumpet tree: 100mg
• N-Acetyl L-tyrosine: 300mg

One dose of Energy consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Motivation

Blood flow and cellular function are at the core of Thesis Motivation . It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Here's Motivation's full ingredients list:

• L-Phenylalanine: 500mg
• Methylliberine: 100mg
• Vitamin B12: 1000mcg
• Forskolin: 250mg
• Artichoke: 450mg

One dose of Motivation consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Creativity

Thesis Creativity aims to realign you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT reuptake inhibition.

Here's a look at Creativity’s ingredients list:

• Alpha GPC: 150mg
• Agmatine sulfate: 250mg
• Panax ginseng: 200mg
• Ashwagandha root: 300mg
• Sceletium tortuosum : 25mg

One dose of Creativity consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Confidence

Confidence is designed to work hand-in-hand with Creativity, using saffron and DHH-B from magnolia bark to increase dopamine levels and decrease anxiety. One fascinating ingredient in this formula is sage extract, which one 2021 study showed can help with various memory tasks, including name and face recognition. 18 It’s worth noting, though, that this study employed a 600mg dose compared to Thesis’ 333mg dose.

Here is Confidence's complete ingredients list:

• Saffron: 28mg
• Magnesium bisglycinate: 500mg
• Sage: 333mg
• Magnolia Bark: 10mg
• Ashwagandha leaf & root: 120mg

One dose of Confidence consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Our Thesis testing results

Our testing team has tried every Thesis formula (with and without caffeine) to determine their short- and long-term efficacy, at least at an anecdotal level. Here’s a quick summary of our experiences:

Clarity provided our testers with a combined sense of focus and mental ease, though we mostly found that it worked best from its second day forward. The very first dose is mildly effective, but it served us better as a loading dose. We had no crash from either caffeinated or uncaffeinated formulas.

Our testers found that Logic provided a similar experience as Clarity, increasing focus and mental acuity, but the caffeinated formula caused a crash in two of our testers. By excluding the caffeine, that crash can be avoided, though that comes at the expense of some efficacy.

We were very curious about how this formula would perform without the caffeine. Our testers had a noticeable increase in energy without jitteriness about one hour after taking Energy. The caffeinated version caused the worst crash of all the formulas, but we were pleased to find that the formula without caffeine still provided noticeable energy increases without a crash.

Our testers are generally a pretty motivated bunch, so we might not have been the best group to evaluate this particular formula. The testers who felt an uptick in a sense of motivation described it more like a feeling of being able to follow through on tasks with less distraction and completion anxiety.

Creativity, like Clarity, seemed to work better for our testers on its second and third days than on its first. Testers generally described a sensation similar to Motivation but without the feeling of being “on rails,” as one tester put it. It seems to allow for more curiosity and exploration, though not necessarily as much follow-through.

This is Thesis’ newest formula, so fewer of our testers have tried it. Among those who have, one tester with a mild case of social anxiety described feeling a bit more relaxed among groups of people. Testers preferred this formula without caffeine.

Thesis pricing, shipping, and returns

Thesis keeps their price structure decidedly simple. This is refreshing, considering the range of nootropics they offer. You don't have to worry about one formula costing you more than another. However, Thesis doesn't make a non-subscription approach economically feasible.

Every Thesis shipment — including the starter pack — consists of four small boxes, each containing six doses of a single formula. That’s 24 doses/month.

Here's how it works:

• Any one-time purchase of a one-month supply, including the starter kit, costs $119.
• When you subscribe, that monthly cost is only $79.
• You can take an extra 10% off your first order with the coupon code INNERBODY

Subscriptions require an account with Thesis, which gives you access to a well-designed customer dashboard. This is where you can easily make formula adjustments, alter your shipping schedule, or cancel your subscription entirely.

Shipping from Thesis is free in the U.S., and the company offers a 30-day money-back guarantee. In our testing experience, we attempted a return on a second shipment into the subscription. While it isn’t the company’s policy to do so, they refunded our money and let us keep the product. This is similar to some other “Keep it” guarantees we’ve seen from competitors, and we appreciated it.

Getting started with Thesis Nootropics

Thesis' website is easy to navigate, but it is inconvenient that you must complete the signup questionnaire before accessing formula-specific pages. There are ways around this — like direct searching or just knowing the formula URLs — but we think reviewing formulas should be a little easier when you first get to the site. And you won’t be able to place an order for anything until you complete the questionnaire.

The user interface for managing your subscription is exceptionally intuitive. You can quickly adjust your formula combinations, specifying whether or not you want specific formulas to contain caffeine.

Setting up a subscription with Thesis is a straightforward process. Here are the basic steps:

• Take the Thesis quiz . This will create a starter kit specific to your results. (You can also build a box from scratch if you know which formulas you want to try.)
• Order your starter kit. We recommend going with the kit Thesis creates after your quiz, but if you change your mind, you can use the customer portal after placing your order to make any changes to the formula combination before it ships.
• Set up a coaching consultation. This is an optional step, but we recommend it and encourage you to have your first consultation before your kit arrives.
• Take your nootropics as needed. Most people can experience some of Thesis nootropics' benefits within a few hours of ingestion. Some ingredients and formulas may take a few days to produce results.
• Refine your order. As you near the end of your first month, you can head over to the Thesis website and customize your next order to include the formula or formulas you like most.
• Set up follow-up consultations as needed. These will help you refine your future orders and maximize your results.

When you subscribe to the starter kit, you will continue receiving that kit every month until you customize your order. Thesis divides their boxes into four six-dose supplies, and you can mix and match those supplies to suit your needs. For example, you could boost energy on the weekdays and creativity on the weekends by getting a one-month supply with 18 servings of Energy in three packages and six servings of Creativity in a single package.

Personalized insights and coaching

When you take the quiz on the Thesis website, you'll get personalized insights comparing your results to other quiz-takers and a data set developed from nearly 500 scientific studies. The parameters in your results cover don’t completely line up with their formulas, but they include:

These results inform the system to make recommendations for your starter kit. After you order, you can set up a consultation with a Thesis coach. These consultations are free, and you can have as many follow-up sessions as you like. Other companies have apps or online resources like blogs or courses to help you on your nootropic journey, but Thesis’ personalized coaching offers a unique approach and execution.

Consultation calls last around 15 minutes, though some of our testers had their sessions go longer as their coaches' schedules allowed. We received best practices information about taking nootropics that covered dose timing, formula application, and more. Some of our testers also received diet and exercise advice that coincided with their formulas.

Alternatives to Thesis

There are generally two tiers of products in the nootropics landscape. The lower tier consists of products that cost between $20 and $40. Many of these nootropics contain proprietary blends that obscure the exact quantities of ingredients, presumably so companies can use more of the least expensive components. Some companies in this tier disclose their ingredient quantities but may not source them from the highest quality suppliers or perform third-party testing of any kind.

Top brands in this tier include:

• Onnit Alpha BRAIN
• Moon Juice Brain Dust
• Focus Factor

The second tier — where you'll find Thesis — consists of more expensive nootropics that spell their contents out clearly, use high-quality ingredients, and often perform third-party testing to ensure safety and potency. Top brands in this tier include:

• Qualia Mind

Hunter Focus

We have a comprehensive breakdown of our top nootropics , but here's a concise breakdown of Thesis' most comparable competition.

TruBrain offers one of the widest varieties of nootropics of any company — one of the few catalogs that rivals the variety Thesis offers. They also have some novel and beneficial delivery methods for their nootropic ingredients. Those include energy bars and liquid shots that are outstanding for anyone with difficulty swallowing pills.

TruBrain offers their nootropics in a targeted fashion, not unlike what you get from Thesis. They formerly offered their targeted blends in shot form only, but now you can get any of these targeted blends in capsule or liquid shot form. The shots come in small 1oz pouches that make them easy to take anywhere.

TruBrain's targeted blends include:

This is TruBrain's original blend. It contains seven nootropics, including Noopept, a branded form of N-phenylacetyl-L-prolylglycine ethyl ester. This blend is caffeine-free.

The Strong blend is identical to the Medium formulation in contents and doses, but it also contains 100mg of caffeine.

The Extra Strong formula builds on the Strong blend by adding 150mg of adrafinil (2-(diphenylmethyl)sulfinyl-N-hydroxyacetamide). 21 This wakefulness-promoting substance may also help with weight loss and athletic performance.

TruBrain's Sleep formula contains just four nootropic ingredients: GABA, melatonin, 5-HTP, and a blend that TruBrain calls "functional oils."

Mellow is identical to the medium strength formula, but it adds the functional oil combination used in Sleep.

This formula contains Lion's mane, a mushroom that may promote neural growth , though human studies are necessary to determine if this is true. 22 Its other nootropic ingredients are rhodiola, guayusa, and rosehips.

A 30-day supply of TruBrain nootropic shots costs $89. That's $10 more than the subscription cost for a one-month supply of Thesis. Some of their shots contain caffeine, and others don't. If it already contains caffeine, there's no way to alter a TruBrain formula to be stimulant-free.

The first month of TruBrain capsules costs a bit less, coming in at $69. After your first month, however, the price goes up to $119. That makes Thesis the better value, but if you want the best possible nootropics for sleep support, it might be worth the extra money to check out TruBrain.

Qualia Mind is a brand under the Neurohacker Collective, a company that offers several products to address things like sleep quality, skin health, and vision. They have three nootropics available:

• Qualia Mind Caffeine-Free
• Qualia Mind Focus

Their original blend is comprehensive, consisting of nearly 30 ingredients in high doses. That means it's liable to provide you with noticeable effects. It also means you might not know which of those effects are coming from which ingredients, and some of the less beneficial components in your body may also have side effects you'd rather avoid.

The caffeine-free version is identical to the original formula but leaves the caffeine out. Qualia Focus is a more streamlined offering with only seven nootropic ingredients, including caffeine, L-theanine, and L-ornithine. 23

Initial shipments from Qualia Mind are significantly discounted, but after the first month, the price makes theirs one of the most expensive nootropics we've tested. For example, the first month of a subscription to Qualia Mind costs just $39. After that, it costs $139/month. And a one-time purchase is $159.

One inconvenient aspect of Qualia Mind is that a single dose consists of seven capsules, which can get tiresome even for people who don't have trouble swallowing pills. On the bright side, Qualia's 100-day money-back guarantee allows you to try it for a little over three months to determine if you can handle that kind of daily dosing.

Hunter Focus is one of three supplements in the Hunter stack alongside the company's Test and Burn supplements. The stack is intended for male use — Test is a testosterone supplement — but Focus and Burn are suitable for men and women.

Like Qualia Mind, Focus has a long list of ingredients in generous doses. In fact, one serving of Hunter Focus is like taking all six of Thesis' formulas at once. That said, the serving itself is difficult to swallow, as it consists of six large pills.

Another knock on Hunter is that they don't offer a subscription system. That means you can't get an extra discount, and you must remember to reorder when you're running low (theoretically, a nootropic like this should boost your memory). There's also no money-back guarantee to speak of, only a return policy with a relatively short window that only applies to unopened products.

One bottle of Hunter Focus costs $90, and shipping is $8.95 unless you buy more than one bottle at a time. The company will throw a fourth in for free if you buy three bottles at once. That's the only way to get any savings through Hunter.

Individual nootropic components

Many companies offer combinations of nootropic ingredients to perform specific brain-related tasks or even provide globally positive cognitive benefits. However, the scientific research behind most of these ingredients almost always includes just one rather than a combination. Some people prefer to try one at a time to minimize the potential for side effects and determine if one particular ingredient works for them. A few companies offer single-ingredient nootropic supplements for this specific purpose.

Our favorite company dealing in individual nootropic components is Nootropics Depot. They offer a wide variety of single-ingredient supplements and a few targeted blends. The prices are generally fair, with an average range running from $16-$70. A 30-day money-back guarantee covers every purchase, and you get free shipping on orders over $50.

Nootropics FAQ

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Specific nootropics affect different parts of the brain in their own ways. Some — like caffeine — reduce fatigue by blocking adenosine receptors, while others act to protect neural connections that are already present while possibly contributing to new neural growth. 24 Some also mitigate depression and anxiety, which frees up the brain to perform at its best.

Are nootropics safe?

The safety of a nootropic depends on the specific ingredients involved. Many are perfectly safe in the doses commonly employed by nootropic companies, but some can cause reactions like increased heart rate, gastrointestinal discomfort, headache, and even tremors. The smartest thing to do is to talk to your doctor before introducing any new supplement to your regimen.

Do nootropics really work?

Many nootropic supplements are noticeably effective — caffeine is a great example. Efficacy varies depending on the specific component or combination. Fortunately, a lot of companies offer money-back guarantees, so you can try their products to see if they work for you without much financial risk.

Will nootropics make me smarter?

Nootropics won't necessarily make you smarter, but many can increase your alertness, improve short-term recall, and promote neural growth and protection. That creates a great environment for learning if you apply yourself while using nootropics, and many ingredients can help you with the motivation it takes to do so.

How do you pronounce nootropics?

The 'noo' in nootropics comes from the Greek nous , which philosophers use to mean mind or intelligence. The 'tropic' in nootropic comes from the Greek tropikos , which relates to turning or changing. So, nootropic roughly translates to mind-changing. You pronounce the 'noo' like 'new' and the 'tropic' with a long O sound, like 'toe pick.'

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Thesis Nootropics Helped Me Ditch My 3-Coffee-A-Day Habit

Here's what to know about the personalized supplement brand.

As someone who pours herself a tall glass of iced coffee three times a day — and sometimes even more, oops — I figured it wouldn’t hurt to look into other ways to boost my energy and focus. Of course, I also try to get enough sleep, water, and exercise, too. But I was also down to try a few supplements from Thesis, a nootropics company that aims to make you feel more productive with its plant-based blends.

If you’re not familiar, nootropics are similar to adaptogens in that they’re a class of functional plants that are buzzy in the wellness world. But nootropics — which include ingredients like ashwagandha , L-theanine , choline , and functional mushrooms — are more focused on activating different parts of your brain to support motivation, mood, memory, and cognitive processing . That’s why they’re sometimes called smart drugs or cognitive enhancers — and thus have a different role to play than everyday vitamins.

At Thesis, you’re hooked up with a kit of personalized vitamins , adaptogens , and nootropics that are meant to help support you in accomplishing your goals and feeling more energized and productive. I tried them out for a month and I have some thoughts. Here’s what it was like to try Thesis, in case you’re also a coffee fiend who could use a little more focus and energy.

• Price: $79/monthly subscription
• Best for: Energy, focus
• My rating: 4/5
• What we like: Personalized supplements, supportive coaches
• What we don't like: Can seem pricey, you have to be ready for some trial and error

What Is Thesis?

To get started, you’ll first take a quiz on the Thesis website that asks you about how you feel on a day-to-day basis, how much coffee you drink, what your energy levels are like, and how much you sleep (among other lifestyle questions) so that it can determine the best supplements for you. It’ll then send you a starter kit with six different supplement blends targeted for each issue you might be experiencing. From there, it’s up to you to decide which ones you want to continue using. It works like a process of elimination — you experiment by taking each supplement for six days to see whether or not it feels effective.

The Thesis line features eight different supplement blends: Creativity, Focus, Motivation, Clarity, Energy, Motivation, Confidence, and Logic. Though the brand notes it would love to formulate one pill that works for everyone, brain chemistry is so complex, so it decided it’s better to take the long route and have customers try multiple supplements in order to find the best fit for their noggin. That’s why Thesis also puts you in contact with a wellness coach, so you can chat and ask questions with an expert along the way.

How Do Nootropics Work?

Nootropics are meant to allow your brain to do its thing, only faster and with more efficiency. So, instead of slogging away at your desk with brain fog , you might notice that you feel perkier, extra organized, and more on-point than you normally do as you continue taking the supplements.

Some of the blends contain the nootropic acetylcholine , which is a neurotransmitter from the essential nutrient choline known for memory, learning, and healthy brain function . There are also plenty of amino acids, vitamins, and plant-based adaptogens in each packet to fight off fatigue and stress while protecting your brain from toxins so it’s easier to take in info — and actually remember what you learned. Other staple nootropics include ginkgo biloba , certain kinds of mushrooms, and caffeine, each of which plays a unique function in your cognitive function.

My Experience

When I took the Thesis quiz , I said that I wanted to improve my energy, focus, and mood. A few days later, I received my starter kit, which contained Clarity , Confidence , Motivation , and Logic all laid out in cute little boxes. You’re supposed to pick one — each box contains six sachets full of pills — and take a packet a day for six days. I was immediately drawn to Clarity, a supplement combo that’s supposed to help with high-pressure situations, concentration, and tasks that require focus and attention. It has Lion’s Mane extract (a mushroom), caffeine, L-theanine , and a few other ingredients meant to support a calm, focused flow. The idea is to take the supplements in the morning so they kick in before you start your day, and most of the effects are said to last from four to six hours.

I’d been taking Clarity for a few days when I had a phone call with Cindy Yan , a Thesis wellness coach and nootropics expert. We chatted about my usual routine, how I’d been feeling, and any questions I had about the process. When I said I felt a slight uptick in focus, but nothing too dramatic, Yan told me the first couple days are called the “loading phase” which is when the nutrients work their way into your body. If you don’t feel anything after that point, it’s a sign the supplement isn’t necessary or right for your neurochemistry. If you do like how you feel, it’s a keeper.

As we chatted about my routine, Yan realized I’d benefit from Creativity, an ashwagandha-based supplement meant for brainstorming and public speaking, so that I could feel like a rockstar at work. I also told her that I tend to crave a nap around 3 p.m., so she suggested the Energy supplement made with choline and mango leaf extract , which you can take every day or on extra-busy days, before a workout , or whenever you want to feel alert.

Talking to a coach as I tested the supplements was a true perk. While the quiz got me started with some great options, having access to Yan helped me hone in on what I truly needed.

Yan suggested I log how I felt every day as I took each supplement so I could keep track of any noticeable differences. A week in, I looked at the scribbles in my notebook and noticed that I did seem more productive during the six days I took Clarity. I wasn’t launching rockets to the moon, but I was getting through my emails and typing away like a woman on fire.

The next supplement on my agenda was Energy, a blend meant for busy days, intense workouts, and staying alert thanks to its mango leaf, theacrine , caffeine, and n-acetyl cysteine — and this is the one that gave me the most benefit. Yan was right on the money. She said I could take it in the morning and/or right after lunch to nip my afternoon slump in the bud, and it truly worked — no fourth mid-day coffee for me.

The more I took Energy, the less I felt like I needed to unhinge my jaw and dump as much cold brew into my face as possible. I found myself drinking a sensible cup or two in the morning, and that was that. Thesis says you can feel the effects of the supplements in as little as 30 minutes or it can take up to five days for all the benefits to sink in as your body and brain adjust. For me, though, Energy kicked in pretty quickly.

The Bottom Line

Typically, Thesis users land on two or three supplements for their regimen. After the month-long trial phase, you can order just the ones you want and forget about the rest. Personally, I’m sold on Energy and can see myself hanging onto Clarity, too.

Thesis seems to have figured things out in the nootropic supplement realm. While the boxes seem pricey, it isn’t so bad when you think about buying each supplement on your own individually — and the fact that you get a wellness coach, too.

TL;DR: I’d recommend it for anyone who feels fatigued, unproductive, or unfocused, or for folks who rely on caffeine to get through the day, like me. You might just find that there’s a better way.

Studies referenced:

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Gelabert-Rebato, M. (2019). A Single Dose of The Mango Leaf Extract Zynamite ® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients. 2019 Oct 28;11(11):2592. doi: 10.3390/nu11112592.

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Malík, M, Tlustoš P. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Nutrients. 2022 Aug 17;14(16):3367. doi: 10.3390/nu14163367. PMID: 36014874; PMCID: PMC9415189.

Mokhtari, V. (2017). A Review on Various Uses of N-Acetyl Cysteine. Cell J. doi: 10.22074/cellj.2016.4872.

Penry, JT. (2008). Choline: an important micronutrient for maximal endurance-exercise performance? Int J Sport Nutr Exerc Metab. doi: 10.1123/ijsnem.18.2.191.

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Silberstein, R. B. (2010). Examining Brain-Cognition Effects of Ginkgo Biloba Extract: Brain Activation in the Left Temporal and Left Prefrontal Cortex in an Object Working Memory Task. Evidence-based Complementary and Alternative Medicine : ECAM , 2011 . https://doi.org/10.1155/2011/164139

Suliman, NA. (2016). Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic. Evid Based Complement Alternat Med. doi: 10.1155/2016/4391375.

Todorova, V. (2021). Plant Adaptogens-History and Future Perspectives. Nutrients. doi: 10.3390/nu13082861.

Wiedeman, AM. (2018). Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. doi: 10.3390/nu10101513.

Curious About Brain Optimization? Thesis Nootropics May Be Your In

Pills for creativity, energy, confidence, and more.

By Will Price and Rebekah Harding

Medically Reviewed by Sydney Greene, M.S., R.D.

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Our product picks are editor-tested, expert-approved. We may earn a commission through links on our site. 

Ever feel like you have the ability but not the willpower or inspiration to excel at your job? Or maybe you’re stuck in a creative rut and are struggling to get yourself out. Thesis , a nootropics company, wants you to stop being so hard on yourself.

Nootropics are the buzzy brain-boosting substances of the moment, and Thesis attempts to match people to different nootropic blends designed for certain needs—creativity, confidence, energy, clarity, logic, and so on. But can you really summon the powers of creativity on demand from a pill? Myself, and fellow Edge writer Rebekah Harding, tried Thesis for three months to find out. Here’s what you need to know. 

Why You Should Trust Us

Hone Health is a team of health-obsessed journalists, editors, fitness junkies, medical reviewers, and product testers. The two authors of this review, Rebekah Harding and Will Price, spent months taking Thesis’ nootropics blends and logging how we felt. We’ve reported on the ingredients Thesis incorporates in its nootropic blends extensively, such as  ashwagandha ,  Alpha-GPC ,  Lion’s mane , and more.

For this review, we opted to review the product and service independently, as nootropics do not all affect people in the same way. Here’s what we found. 

Thesis Nootropics

Personalized recommendations.

• High quality ingredients, third-party tested

Excellent customer service

Not for everybody, what is thesis.

Thesis’s thesis (sorry, I had to) is that you are capable of more. But as co-founder and CEO Dan Freed says on the back of the box the pills come in, “…people thought I was lazy, stupid, or unmotivated. I knew there was more in me.” Freed and his brand propose that the solution to this conundrum many of us face may be nootropics, which are substances that aim to improve cognitive performance. 

New users are funneled through a quiz that determines the best nootropic blends for them—each named for the feeling they’re meant to evoke, e.g. confidence, clarity, creativity. Boxes come with four blends, each of which should last one week, with auto-renewing deliveries shipping at $79 a month. (Note: you can buy Thesis for just one month, but it will cost $119). 

You’re meant to take notes on how each blend makes you feel and, after you’ve completed your first box, adjust which blends you receive going forward.

What are nootropics?

Nootropics are medicinal substances (some pharmaceutical, some natural) that take aim at improving brain performance—memory, creativity, motivation, mood, as well as anxiety reduction and sleep improvement.

While most have heard of popular nootropics like caffeine , creatine , or nicotine , most over-the-counter nootropic supplements—like Thesis—are formulated largely with herbs, vitamins, minerals, and other natural compounds that are known to benefit the brain.

Thesis ingredients

Each Thesis blend contains different ingredients, many of which are supported by solid research. Here are a handful. 

Lion’s mane: Mushrooms that contain hericenones and erinacines, which can stimulate nerve growth and may offer potential cognitive benefits ( 1 ). In addition to thinking capacity, these mushrooms may lower the risk of age-related brain diseases, like Alzheimer’s disease ( 2 ).

Alpha-GPC: May increase your levels of a neurotransmitter called acetylcholine, which facilitates memory and learning, and plays an important role in cognitive function ( 3 ). 

L-Theanine: An amino acid that can positively affect mood. Studies have found L-theanine may be a beneficial nootropic for mood and mental health. It may also help ease anxiety and stress levels ( 4 ).  

Ashwagandha: An ancient herb taken for thousands of years, ashwagandha is an adaptogen that has been found to reduce cortisol —stress—levels in humans, which can have a number of powerful knock-on effects on the brain ( 5 ). 

DHA (Omega-3): This omega-3 fatty acid plays a role in supporting cognitive function and promoting growth and maintenance of brain cells . Research suggests that DHA may improve memory, learning, and overall cognitive performance ( 6 ). 

Synapsa: This patented extract of Water Hyssop boasts nootropic benefits such as enhanced memory and cognitive function ( 7 ). Research shows that taking Synapsa regularly may improve your information processing speed, increase your attention span and enhance your memory ( 8 ).

Ginkgo Biloba: Ginkgo Biloba has antioxidant properties, which are associated with cerebral blood flow and neuroprotection ( 9 ). Studies suggest that this nootropic may boost memory, mental clarity, and overall cognitive function ( 10 ).

Theacrine: This natural plant compound acts as a mild stimulant, without the tolerance build-up and jitters associated with caffeine ( 11 ). Theacrine may boost energy, mental clarity, and focus.

What’s Good About Thesis Nootropics?

There are a lot of folks interested in nootropics. Google reports something like 100,000 monthly searches for the term each month. The issue many have is simple: nootropics aren’t easy. 

It’s not easy to know what companies are selling legitimate products and which are pushing low-grade stuff. It’s not easy to get a handle on what the many, many different nootropics are meant to do. Sometimes it’s not easy to know if the good week you just had was thanks to a nootropic you just took, or the absence of some stressor you forgot about. Then there’s dosage, doctors, and the way in which these substances play off each other to worry about. 

Getting your foot in the door with nootropics is a challenging task. Thesis’s approach is designed to simplify this, and it largely works.

The personalization is somewhat limited, in that the blends themselves cannot be changed, but the blends you receive can. Interested customers are prompted to complete a simple questionnaire that asks about physical traits as well as your goals in taking nootropics. You’re then given a “Starter Kit” that includes four different blends suited to what you’re after. 

High-quality ingredients

The more you delve into nootropics, the more you realize there are, broadly, two classes of company: the legit class and the not-so-legit class. Thesis, by our account, is the former. The company’s products are products in FDA-approved cGMP facilities, which ensures the manufacturing of the product is sound. More importantly, though, and this will sound humorous if you’ve never shopped for nootropics, Thesis actually tells you what’s in its blends. 

Thesis is not the only company selling nootropic blends as a shortcut for people not interested in doing months of research. There are a great many companies that don’t specify ingredients (“focus blend”) or, more commonly, aren’t clear on dosage of each individual nootropic.

Thesis’s nutrition label is crystal clear on what’s inside each serving of its nootropic blend.

When launching oneself into a health category one doesn’t know much about, having a friend can be helpful and reassuring. Thesis’s customer support service—available via email or phone—is the weird science friend you need. 

I pestered them numerous times and each issue was responded to and resolved within 24 hours every time. The first time I called. Is there a way to remove the caffeine from the blends (there’s 100mg, or a cup of coffee’s worth in each pack)? You can request non-caffeinated blends on your next order, but for the time being simply don’t take the white pill in the daily dose packet. My email questions were answered with similar speed as well. 

There’s also Thesis’s coaching feature, which is effectively customer service for questions about your specific blends, how the blends make you feel, and so on. When I called into it I mentioned that some of the blends made me slightly antsy, some made me feel great, and others seemed to have no effect at all. Not only is this common, it’s expected: these substances do not affect us all in the same way, so there is a necessary trial period to get through. 

Having a source of reassurance when trying something new to improve our health makes the process more comfortable. 

MENTAL WORKOUT

What’s Not Good About Thesis Nootropics?

As previously mentioned, not all blends will work for you. Several reviews online suggest there are people for which none of them will work. My fellow reviewer and I each found one or two blends that worked especially well, some blends that didn’t seem to have any effect at all, and others that caused some minor anxiety. 

This is sort of the rub with nootropics. Different people will be hit different by different nootropics ; and even then there is the matter of dosage and duration, as most research suggests there is bedding-in period associated with nootropic effectiveness ( 12 ).

So is this a con for Thesis or for nootropic supplementation more generally? It’s a little of both, but more so a hurdle with the wider world of nootropics.

If you’re already waist deep in nootropics as a hobby or interest area, you can likely build your own nootropic stacks for cheaper than what Thesis offers.

Thesis costs $79 a month, or $3.29 per serving, once you’ve set up your account for automatic renewal. This is, unsurprisingly, on the middle-higher end of the nootropic blend market. 

Budget brands like Focus Factor come in at less than a dollar per serving. Mind Lab Pro , a brand closer to Thesis’s efficacy and quality, goes for about $2.10 per serving. The popular NooCube blend is also about $2.15 per serving. 

It should be said that I’m obviously comparing apples to oranges here. Each of these blends are made of up different stuff. Each of these companies is selling to a different customer. It could be argued that Thesis’s hyper responsive customer service and task-focused personalization model makes the $79 a month bill a fair deal. That said, the price doesn’t pull you in quite like the promise the rest of the product provides. 

What It’s Like to Take Thesis Nootropics

Tester #1 info : Female, 23 years old Reason for taking : diagnosed ADHD, brain fog, difficulty concentrating, anxiety Blends taken : Confidence, Motivation, Energy, Clarity

When I was diagnosed with ADHD in 2016, everything clicked. I’ve struggled with brain fog, task paralysis, and extreme difficulty concentrating for as long as I can remember. But all I have to show for my diagnosis is a raging caffeine addiction, two failed tries at taking prescription stimulant medication, and an ever-changing-never-working supplement stack.

As a neurodivergent person, the idea of nootropics—supplements that may improve cognitive performance—is intriguing to me. The idea of spending hours researching different blends and stand alone supplements, however, is not. That’s where Thesis comes in. 

To order your four-blend starter kit, Thesis kicks things off with a quick 25-question quiz. The questions were quick and multiple choice, and didn’t take more than a couple of minutes. (As a company that markets to ADHD-ers, I have to say they know their audience.) The quiz covers questions like how much sleep you clock in each night, your typical mood, and your procrastination habits—and a memory test at the end that I won’t spoil. At the end, you plug in an email and receive a customized recommendation based on your goals and struggles. 

I’m ultra-productive, but I have extreme anxiety and frequent brain fog depending on the state of my hormones. Thesis recommended four blends—Confidence, Motivation, Energy, and Clarity—to boost my mental health, promote relaxation, and fight off brain fog. 

I took each blend for six days each—as directed—with one day in between to reset.

Week one I opted for Confidence—a blend that includes saffron, ashwagandha, sage, and magnesium—which oddly produced the opposite of its intended effect. Two days in, I ditched the separate, white caffeine pill in the packet, but that only alleviated my anxiety slightly. Week two, I took Motivation—which contains artichoke extract, vitamin B12, methylliberine, and L-theanine. I enjoyed this blend the most, and felt like my mood and concentration got a decent boost. Weeks 3 and 4 I took Energy (mango leaf extract, theacrine, citicoline, and more) and Clarity (Lion’s Mane, L-theanine, and more) respectively. I noticed no changes these weeks.

Overall, I think Thesis is worth a shot for the nootropic-curious. Especially if you don’t have the time or patience to research these trendy supplements. However, I don’t think I’ll be stocking up on any of their blends any time soon.

BRAIN GAMES

Tester #2 info : Male, 30 years old Reason for taking : brain fog, unfocused, spark creativity Blends taken : Clarity, Logic, Creativity, Energy

I’ve not been evaluated for or diagnosed with any neurological or neurodevelopmental matters, but I have struggled to train my mind’s gaze on one thing for long periods of time for as long as I can remember. Call it brain fog or something else, it’s been a persistent issue of mine going back to my high school and college years, where I’d substitute just about any distraction available to me instead of something that would require real attention.

A Thesis ad on Instagram suggested this issue may not be my own failing (a source of great personal anxiety), but perhaps something that could be fixed with nootropics. I’m willing to believe most anything that suggests my failings are not my failings, so I ordered my personalized starter kit. 

My kit came with the Clarity, Logic, Creativity, and Energy blends. I quickly eliminated Clarity and Logic from the rotation, and both seemed to trigger a mix of uncomfortable headaches and anxiety (a quick browse of the internet suggests this isn’t an uncommon reaction to these specific blends). Energy, while effective, wasn’t the most useful to me, someone who doesn’t struggle as much with alertness. 

Creativity was different, though. During the second month of testing, once I’d taken Creativity for a few weeks straight (remember there is a bedding-in period!), things started to click. I started to feel the gears turning a bit more in brainstorm meetings at work, and I could think more deeply about how I could build a workout plan for a friend.

That’s how I would describe the feeling: a noticeable but slight improvement in my ability to untangle a problem of some kind. It wasn’t as though the shackles of my brand were removed and I launched a Fortune 500 company which, thankfully, Thesis does not suggest in any of its marketing materials. 

I’ve taken the Creativity tablets for a few months now and find them to be good value for the money, for me. For those curious about nootropics, I think of Thesis as the ideal first stop. Once you figure out what works for your brain and needs, you might seek out other solutions. 

The Bottom Line

Thesis nootropics are probably the best way to get into nootropics without having to do loads of research. The brand isn’t the cheapest out there, but the product is quality and the customer service is excellent.

Lai, Puei-Lene et al (2013) https://pubmed.ncbi.nlm.nih.gov/24266378/

Skubel Tomasz et al (2022) https://www.researchgate.net/publication/363300485_Therapeutic_potential_of_Lion

Ham, Juhee et al (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645066/

Williams, Jackson L. et al (2019) https://pubmed.ncbi.nlm.nih.gov/31758301/

Lopresti, Adrian L. et al (2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/

Yurko-Mauro, Karin et al (2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364972/

Downey, Luke A. et al (2012) https://pubmed.ncbi.nlm.nih.gov/23281132/

Kumar, Navneet et al (2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/

Mashayekhu, Ameneh et al (2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163160/

Ge, Wei et al (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014356/

Bello, Marissa L. et al (2019) https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0287-6

Malik, Matej et al (2022) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415189/

About the author

Will Price is Hone Health’s Senior Lifestyle Editor. Before Hone he was Gear Patrol’s home and drinks editor.

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Thesis Nootropics Review

WellStart Health is reader supported. We may earn a commission when you purchase through links in our content. Our reviews are fact checked for accuracy and adhere to our strict editorial guidelines.

Thesis Nootropic takes supplementing to a whole new level – and a whole new price tag. Is it worth the investment? Find out how we got on with our trial in this Thesis Nootropic review.

The nootropics field isn’t exactly new. The term itself was introduced back in 1972, while many of the core nootropic ingredients have been used for their benefits for centuries.

And there is no denying it, nootropics do help with our cognitive function and health, which is why they have gained substantial attention in recent years.

However, though we often see repeat appearances from certain nootropic ingredients, especially in the best nootropics out there, occasionally we come across a brand that approaches the standard way of supplementing with something slightly different.

Enter, Thesis Nootropics. These guys stand out in the market with their strong emphasis on personalization . They understand that every one of us is different, and hence, our cognitive needs and goals vary as well.

As such, their approach is to provide tailored nootropic formulas that meet these individual differences .

In the sections to follow, we will discuss more on Thesis Nootopics’ offerings, their key ingredients, and their potential impact on cognitive performance – plus the results of my own personal experience with this different approach to finding the best nootropic.

Quick Verdict: Thesis Nootropics

Thesis Nootropics has six blends – Clarity, Creativity, Logic, Energy, Motivation, and Confidence, each with high-quality ingredients.

A questionnaire will help you understand which it is you need, plus you have experts to hand to guide you along the way. The result is that you find a nootropic that your body responds to best, and provides all the benefits you need the most.

Thesis Nootropics are more expensive than your standard nootropic supplement. But if you want the knowledge and understanding as well as a unique stack of ingredients that work especially for you, it’s a worthy investment in yourself.

What Is Thesis Nootropics?

Thesis Nootropics isn’t your run-of-the-mill supplement. It has carved a niche for itself in the competitive cognitive supplements market by focusing on customization.

Each ingredient goes through a battery of tests – internal testing, customer beta testing, and third-party lab testing for safety and purity. I’m all about transparency – and Thesis provides it in spades.

To ensure that each individual gets the most uniquely suitable cognitive enhancement, Thesis Nootropics starts by capturing the user’s cognitive baseline .

By taking an in-depth assessment online, Thesis examines your mental performance and your specific cognitive objectives.

Based on this foundation, Thesis then tailors its products to fit your unique cognitive blueprint. They propose a Starter Kit, allowing you to try four of their pre-made blends over a month to discover the most fitting mix for your cognitive enhancement.

As a regular nootropics user, I found this method intriguing. In many cases, supplements come in a ‘one-size-fits-all’ format. With Thesis Nootropics, it’s a refreshing shift towards personalized wellness .

Thesis Nootropics use a variety of ingredients in its blends, all aimed at enhancing cognition . Their blends include common nootropics such as Alpha-GPC and Lion’s Mane Mushroom, but also unique ingredients like Mango leaf and Indian Trumpet tree.

Each blend is even available in a caffeine-free alternative – the same blend, but without the caffeine and L-Theanine in it. I really love this. It means everybody can find their perfect nootropic with the right balance between stimulation and relaxation.

These comprehensive ingredient formulations speak to Thesis’s commitment to cater to a wide range of cognitive demands. It’s clear that a lot of thought and expertise is going into each blend.

You also have an expert to hand for personalized advice , which is something very unique indeed. Their responsiveness, especially over the phone, has garnered rave reviews. This eye for detail and dedication to customer satisfaction hardly go unnoticed, further solidifying Thesis Nootropics’ position in the market.

There is no doubt about it: Thesis Nootropics lean on the pricier side. The monthly cost is $79, or about $3.29 per serving. This places the brand on the higher end of the nootropic blend market. For comparison, budget-minded brands such as Focus Factor offer similar blends for less than a dollar per serving.

Even premium brands like Mind Lab Pro and NooCube have products priced around $2.10 and $2.15 per serving. So, Thesis Nootropics may strain your wallet more than other options in the market, but it could be worth it. Let’s find out why.

Benefits Of Thesis Nootropics

The Thesis Nootropics line is comprised of six different blends: Energy, Clarity, Creativity, Logic, Motivation, and Confidence.

What’s enticing is how each blend targets distinct cognitive areas. For instance, if you’re struggling with focus, the Logic blend might be a suitable choice. Alternatively, if you’re lacking motivation, they’ve got a blend especially for that too.

Their blends use a variety of potent ingredients. You’ll find a selection containing adaptogens, like Ashwagandha Root, that aid stress management. The inclusion of amino acids and herbal extracts, such as Lion’s Mane Mushroom and Sceletium Tortuosum, have been documented to support brain function.

Ultimately, with Thesis, you can choose which benefits you get from Thesis. Here is an overview for each:

Each stack is engineered to precisely meet the specific cognitive demands of its user. Now that’s a smart approach to smart drugs.

Thesis Blends & Their Ingredients

With its six different blends here, I’ll try and keep things slick and to the point. One consistent pattern throughout all of them is the caffeine content, which you can toggle on or off for your customization.

So if you see it included in the list, remember the option is there to remove both the caffeine and L-Theanine for non-stimulant nootropic.

Thesis Clarity is the blend that works on your attention span and focus . If this is something you struggle with, and if you suffer with brain fog, then Clarity is a great blend to consider.

The DHF, Alpha GPC, and Lion’s Mane are here to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention. It’s particularly adept at cutting through brain fog.

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used. Leaf extracts specifically tend to produce a calming effect on the mind and mood, reducing those unnecessary distractions.

Thesis Logic aims to help us process information faster, think deeper, and memorize more easily.

It contains Triacetyluridine, which caters to the health of the entire central nervous system, while Phosphatidylserine helps facilitate communication between and protection of brain cells.

Thesis Energy uses Cysteine and Tyrosine alongside caffeine to deliver a steady energy supply.

It also includes TeaCrine, a branded form of Theacrine, which partners with Caffeine to affect adenosine signaling and prevent fatigue.

Motivation is the perfect blend if you need support with managing stress, tackling challenges more easily, and fueling your achievements with willpower.

Blood flow and cellular function are at the core of this blend’s targets. It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Creativity isn’t as fluffy as it sounds. When your mind is stretching its boundaries, you’ll find you can problem solve and find solutions and ideas more easily.

Thesis Creativity aims to realign you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT re-uptake inhibition.

Confidence is designed to work hand-in-hand with Creativity, using saffron and DHH-B from magnolia bark to increase dopamine levels and decrease anxiety. You should feel calmer and less stressed, which should aid your ability to think clearer and be confident in your decisions.

One fascinating ingredient in this formula is Sage Extract, which one 2021 study showed can help with various memory tasks, including name and face recognition. It’s worth noting, though, that this study employed a 600mg dose compared to Thesis’ 333mg dose.

How Do You Use the Thesis Blends?

If you’re building your own, you can select the ones that you think (or the questionnaire advises) will give you the benefits that would help you the most in life.

Choose four, then you can track how you respond to them over a week. This gives you the opportunity to ‘see for yourself’ how best your body responds, plus you have an expert to hand.

The outcome will be that you discover a nootropic blend that is perfect for you.

My Experience With Thesis

For someone like me who is always curious to explore new possibilities in personal wellness and mental improvement, Thesis Nootropics was something that I had been looking forward to trying out. The promise of customized nootropic blends, backed by a legitimate understanding of my cognitive baseline, was certainly a unique proposition.

The process of getting started was simple. It started with easy-to-answer questions, such as age and weight, and the areas in life you think you need support.

But then the questions really did escalate, delving into areas that helped paint a precise picture of my mental framework and personal goals. Questions such as ‘ How much do you procrastinate? ‘, or ‘ Do you feel regret when thinking about the past? ‘.

At this point, I found it all a bit much. I wondered if they were simply bulking up their questionnaire to make themselves look good, but for me it actually just felt overly personal for a nootropic.

However, it was no big deal to keep going, and I continued throughout the many questions, until Thesis recommended some blends to try. Blends, to be honest, I could’ve predicted myself, but that’s perhaps unfair judgement as I’m used to studying them.

I then easily contacted a wellness coach to see how well they delivered on this unique service. I got a prompt answer and she was very knowledgable on all the blends and ingredients, and seemed genuinely interested in my personal results.

Based on her suggestions and help, I felt confident I would have some good results. Thus far, the experience I’d had with Thesis was something I’d never had before – I can see how hugely beneficial it would be particularly for someone who wants to learn about nootropics and blends.

During my trial period, the Energy and Clarity blends had the biggest impact on me. While the Energy Blend kept me alert and focused without the jitters common with caffeine-based products, the Clarity Blend accentuated my mental sharpness on a noticeable level.

By the end of my trial, I did feel like I’d nabbed a nootropic that really was personal to me. My body agreed with it. It responded well, and I noticed all the benefits I specifically wanted to improve on.

That’s full marks, right?

Well, there is the cost to consider. You’re paying extra for the personalization of it all. As someone who trials a lot of nootropics, I didn’t feel I needed this. Decent nootropics like NooCube don’t need to personalize their formula for it to work – it just works, really well, and at a lower cost.

However, you cannot dispute that Thesis have their own niche here, and it’s perfect for someone who wants to study the effects different nootropics can have on them personally. After all, we are all very different, and what works well or not at all for one person could be life-changing for another.

Thesis also use really high-quality ingredients that have a lot of clinical backing. I could feel the difference in supplementing with them, especially with Clarity and Energy. Even better is that they’ve clearly spent a lot of commitment building unique blends with and without stimulants.

Thesis really do create something for everyone, and I found a highly effective nootropic through their exploration and support.

Thesis Nootropic clearly offers a unique approach to cognitive enhancement. It’s all about personalization, tailoring blends to individual needs, and offering a comprehensive array of ingredients aimed at boosting various mental aspects.

The nootropics themselves help elevate clarity, energy, creativity, and more. But the USP for Thesis is the knowledge it provides. It helps us learn what works best for our bodies, and why.

And the blends are effective. They’re carefully curated and dosed well, with the option to choose between caffeine content and without.

However, all this personalization comes at a cost. From my own personal experience, NooCube works well for me; it has an excellent formula that draws in many, many positive user reviews at a much lower price point.

That being said, I’m used to trialing nootropics. I know what to look for, and what should and shouldn’t work.

If you’re new to nootropics, Thesis can be an incredibly helpful entry point. It’ll help you understand the areas you need help with (you may even learn something about yourself along the way), and you have experts to help guide you as you trial your way to the perfect blend.

If you want straightforward, NooCube is great. If you want the gold standard of understanding nootropics for you specifically, Thesis Nootropics are incredible. With them, it’s all about finding what works best for you.

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258547/
• https://nrl.northumbria.ac.uk/id/eprint/45218/1/nutrients-13-00218.pdf

Jason has written across a wide range of health and wellness publications and is passionate about men's physical and mental wellbeing. He is well versed in the field of sleep, nootropics, nutrition and physical fitness. Current wearable tech of choice is Oura Ring and Whoop Band.

What Is Thesis?

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• ThesIs Nootropics Review

Thesis Nootropics Review (2024) Is It Worth The Hype?

As a fitness coach, I've seen the impact of high-quality nootropic supplements on motivation and concentration during workouts.

Teaming up with my dietitian and 12 clients, we documented the significant cognitive benefits and general effects of Thesis over a period of four weeks.

Does it genuinely fulfill its promise of enhancing your mental performance and focus?

Before trying out the supplement, keep reading and find out if it's right for your mental wellness needs.

Thesis is a stack of supplements that aims to improve cognitive function, mental stamina, mood, and overall mental energy levels.

Thesis nootropics' energy formula claims to boost energy levels while catering to individuals following a certified gluten-free diet, promoting positive habits and supporting nerve health.

What's particularly interesting about purchasing this stack is the Thesis algorithm.

It’s a set of questions that assess your personal needs to create a bespoke starter kit.

More on this shortly.

As a result, you get a recommendation from a couple of their products to provide personalized blends for nootropics.

Let’s learn more about how Thesis supplements work with your brain health.

Thesis Nootropics

Rated With Total Shape's Scoring System

The Thesis experience begins with a questionnaire to assess your needs and goals, like improved physical and mental energy.

Based on your responses, the algorithm will recommend different Thesis blends to help you achieve your goals.

After going through the quiz, you get a recommended Thesis starter kit.

The five different products Thesis then recommends claim to work similarly to smart drugs by boosting your cognitive function and mood.

But unlike prescription medications, Thesis uses natural ingredients like vitamins, amino acids, minerals, and herbs.

“Nootropics, a greek word meaning 'Towards the Mind', are compounds that are both (1) neurologically active and (2) directly or indirectly enhance cognitive potential via increased capabilities (ie. reflexes), state of well-being, or learning potential.” - Kamal Patel, MPH, MBA at Examine.com

Once you are a Thesis customer, you can also set up a meeting with a Thesis coach to review your stack and the effects you are looking for and experiencing.

But does that make Thesis legit?

Let’s see what our detailed clinical research reveals.

The first thing that we got our testing team to do is to go through a full week of keeping an hourly journal to self-evaluate their mood, concentration, and cognitive function.

Then we put them through three weeks of taking their Thesis recommended stack and got them all to keep their hourly journaling going.

The first thing we noted was that the energy blend and creativity formula seemed to give our clients a good boost in brain performance.

And the folks that took the motivation blend a few hours before heading to the gym also found they were more focused on their workouts.

However, the majority of our test group highlighted that the effects seemed to wear off after about 4–5 hours.

We also noted that the logic formula didn’t provide a huge benefit, which could be down to a lack of a proven formula.

We also found that the Thesis nootropics cost can mount up if you want to stack a few of them.

• Allows you to combine different product formulas for personal goals
• Provides support from coaches to help you refine your stack
• Positive impacts on mood and concentration levels
• Some of the ingredients are not supported by reliable clinical trials
• You may need to swallow quite a few capsules, depending on your particular blend

Thesis Nootropics offers a unique blend of ingredients that target thesis energy, thesis creativity, cellular function, and even skin health, making it a notable contender in the supplement industry.

For this part of the Thesis supplements review, I got my dietitian to help out and analyze the Thesis formula for each of the products.

We also tested the effects with 12 clients to see whether the marketing hype lives up to expectations.

Let's have a more detailed look at the features and benefits of each blend.

Thesis Energy Benefits

The idea behind Thesis Energy is to help people clear brain fog and feel more mentally energized.

To verify this, we paid close attention to the journal entries our testing team made in the afternoons. This is typically when people feel a slump.

What we found was that folks who took this supplement after lunch gained some mental clarity.

But it seems like the effect wears off after about four hours, so you don’t gain an all-day effect like with other nootropics.

Key Ingredients:

• Choline: According to PubMed, this mineral may boost memory function and verbal fluency [ 1 ].
• L-Theanine: A controlled trial posted in Nutritional Neurosciences suggests that this amino acid can work well with caffeine to increase alertness without causing jitters [ 2 ].
• Caffeine: This stimulant can boost alertness, but you can get this from a morning coffee, so I’m not overly impressed that it’s added here [ 3 ].

Clarity Benefits

Thesis Clarity is another product that aims to improve neural communication and allow you to think more clearly and effectively.

Thesis Nootropics' clarity formula provides an extra boost of cognitive performance, targeting stress response reduction and improving sleep quality, all while delivering a healthy dose for enhanced mental clarity and improved ability.

We did note in our testing review that there seems to be an improvement in mental function for several hours after taking it.

But this also seemed to happen more with those testers who took the clarity and energy formula.

• 7,8-DHF: Studies have shown that Dihydroxyflavone can cross the blood-brain barrier and act as a neuroprotective ingredient [ 4 ].
• Alpha GPC: This is an ingredient that has been shown to protect against neurological decline [ 5 ].
• Lion’s Mane: This mushroom is common in nootropics and has been shown to improve mental performance and creativity [ 6 ].

Motivation Benefits

A large part of improving mental health comes down to how focused and motivated you are with daily tasks. Our clients who tested the Thesis Motivation noted that it seemed to help them remain more motivated during workouts.

But this doesn’t seem to happen if you take it in the morning and go to the gym later in the day. So you’d need to get your timing right.

• L-Phenylalanine: Research has shown that this ingredient can help with signs of depression and improve overall mood [ 7 ].
• Dynamine: Also known as Methylliberine, studies have highlighted that it can impact your mental well-being when combined with caffeine [ 8 ].
• Forskolin: The interesting thing about this herbal ingredient is that it can improve blood flow to the brain for better focus and motivation [ 9 ].

Logic Benefits

For this product, we looked at what our clients noted in their journals when they were at work or studying. While they did find a boost in focus, none of them noted that it helped improve verbal fluency or problem-solving skills.

• Ginkgo Biloba: This is a common ingredient in traditional medicine, but modern clinical trials have shown that it can help brain health through improved blood flow and anti-inflammatory properties [ 10 ].
• Ashwagandha: This herb can have a direct impact on stress and memory, allowing you to think clearly and effectively [ 11 ].
• Saffron: It’s the most expensive herb in the world, and studies have linked it to improved stress, mood, and cognitive capacity [ 12 ].

Creativity Benefits

A few of our clients tried the creativity blends, but this is one of the products where most of them didn’t report any significant improvements.

Combinations with other products above did positively impact mood and stress, but we couldn’t find any comments where our clients highlighted that they felt more creative in their work or any other creatively demanding context.

• Agmatine: This amino acid doesn’t just boost cognitive performance but may also help to protect brain cells against oxidative stress [ 13 ].
• Zembrin: Research has shown that this herb can impact both stress and anxiety, but there’s no specific evidence that it can help with creativity [ 14 ].
• Ginseng: This is a common ingredient in diet supplements as it can improve blood sugar levels, but that wouldn’t directly influence creativity [ 15 ].

We also asked all of our clients to provide any feedback they had on side effects related to the nootropic blends.

Overall, the majority of people found that it didn't cause any major issues.

We only noted that one person had a bit of a rash, which could have been a result of an allergic reaction to one of the ingredients.

We also found that it’s best not to take these capsules on an empty stomach. Ideally, take them within 20 minutes of eating a meal to avoid stomach upset.

Based on my personal experience, people who want to achieve a moderate boost in brain function may want to take nootropic supplements.

You would need to experiment with the timing as these capsules don’t provide effects for the entire day. But after about a week, you should be in a position to spread out the capsules for maximum effect.

You can also contact a coach directly for advice on timing. It's especially important when you have no prior experience in taking these supplements. However, a good starting point is to take the minimum and adjust from there.

Based on our own experience, people with high blood pressure or neurological diseases shouldn’t take Thesis natural nootropics to enhance cognitive function.

In such cases, it’s best to have a doctor review your detailed medical history and the nootropic ingredients for any potential side effects.

Our testing team didn’t note any improvements whatsoever, and when we specifically asked them after the trial, none of them said they saw a noticeable difference.

You can buy Thesis Nootropics directly from the company website.

We generally recommend avoiding third-party retailers to ensure that you always get the real product, so this is a positive highlight.

We placed two orders, and the package arrived within four days, which is about average for nootropic supplement companies.

One thing to point out on the Thesis supplements shipping policy is that currently, the company doesn’t offer international shipping.

We also had a look for other nootropic reviews online to see what users were saying.

“It gave me more energy. I have struggled with low energy and I felt like my old self again. I could get up & get things done.” - Laurie C., taketheseis.com

“After 1 month of using Energy, Creativity, Clarity and Logic pack, I do not note any difference in mindset. I opted for the non-caffeinated blends as I am not a big caffeine person to begin with so a caffeinated blend might show some improvement.” - Beefnug, Reddit

“I have been continuously nauseated every day using thesis packets. I have given it a week and a half and cannot handle the negative side effects. Disappointed.” - AdGroundbreaking5162, Reddit

Our Thesis scientific research suggests that it doesn’t compare well to our testing of three other products for improving cognitive function.

First of all, we looked at the results we have for Mind Lab Pro .

The one thing that stands out the most is that it seems to be effective for many more hours than Thesis, so the timing doesn’t become an issue.

The second one we compared is Onnit Alpha Brain . This nootropic supplement seems to provide a lot more focus and motivation, especially while you’re at the gym.

Compared to Gorilla Mind Smooth , Thesis doesn’t have the same effect on boosting energy and reducing stress.

Related Articles:

• Avantera Elevate Review
• Best Nootropics For Men
• Best Nootropics For Women

Is It Safe To Take Thesis Nootropics Every Day?

Yes, it is safe to take Thesis Nootropics every day. We found Thesis to be generally easy to process, but you need to look out for allergies to any of the ingredients. A good way to do this is to ask your physician for advice since they will know whether these ingredients are good for your health.

Does Thesis Nootropics Contain Banned Ingredients?

No, Thesis Nootropics doesn’t contain any banned ingredients. All of the ingredients are based on minerals, amino acids, and herbs that won’t cause a positive drug test result.

Based on our feedback from a nutritionist and the test results with 12 clients, we don't recommend Thesis.

Not only do its effects wear off after a few hours, which makes timing your intake a problem, but it also burns a hole in your pocket for just a stack of three or four products.

Instead, I highly recommend one of the best nootropic brands we have tested so far: Mind Lab Pro .

Our results show that its effects last for most of the day and provide great clarity, energy, focus, and concentration, making it a favorite among clients of all age groups.

We Recommend This Instead

Mind Lab Pro

• Great combination of herbs and amino acids that work as a cognitive enhancer
• Added B vitamins to support red blood cell production and boosted energy levels
• Great feedback from users that it can help with relieving anxiety
• Get the BEST PRICE until the end of October
• The capsules are not the smallest ones to swallow

About The Author

James Cunningham is an author and dietary supplement connoisseur with a solid academic foundation, holding a BSc in Sport & Exercise Science from the University of Hertfordshire. Specializing in Performance Psychology, his expertise is backed by both rigorous study and practical experience.

As an author, James is committed to guiding his readers towards optimal health and performance, providing actionable insights and strategies through his writings.

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Thesis Review | I Tested this Nootropic for 4 Weeks, Did It Work?

In this Thesis review, we’ll take a long look to this nootropic company that offers combinations of various nootropic blends that are tailored to best suit your individual needs.

A thesis, usually presented as a final work for an advanced degree, is a fitting name for this product as there is a several-question quiz that seeks to get a handle on who you are and what you need help with in order to recommend a suite of products.

Those brain supplements comprise of the following blends.

If you have been struggling with anxiety, stress, productivity or energy, you might have certainly looked at brain supplements. These are usually generic blends of natural herbs and mushrooms with positive effects in various areas and processes in your brain.

However, most of the best brain supplements offer comprehensive blends that are suited for 90% of the population. Thus, Thesis offer of tailored nootropics is a very intriguing proposition. But does it work? Does Thesis help you combat anxiety? Help you focus? Is it worth it? Let’s find out!

Table of Contents

Thesis Review at a Glance

• Approach to This Thesis Review

Thesis Nootropic Ingredients

Who wrote the thesis, price and shipping, customer thesis nootropics reviews.

• Verdict: Thesis Review – 4 Weeks with Noticeable Effects

Key Takeaways

• Offers personalized nootropics
• Transparent label
• Effective when tested at increasing clarity and focus
• Good sets of ingredients
• Not the most affordable but worth the price
• Best for long-term use

Approach to This Thesis Nootropics Review

As I alluded to, Thesis presents a questionnaire so to individualize your box. It takes around five minutes to complete, and asks questions that are quantifiable, yes/no or degree based. Everything from your weight, age and sleep quality to how often you exercise, which unhealthy habits you indulge in and how much you procrastinate will all be on the table.

Now, you can skip that entire process and just opt for a starter kit. With the starter kit, you can just simply pick blends you prefer, and you’re off and running.

I’ll be taking four of the six blends for six day intervals and documenting my results. So by the time you’re reading this, I’ll have tried Thesis for the better part of the last month.

It will be a thorough test on the day to day to learn how effective Thesis really is.

So, each blend of course has its own unique formula consisting of ingredients that are supposed to aid in its intended goals. Each blend contains 100mg of caffeine and 200mg L-theanine (unless you opt for caffeine free) and the ingredients differ from there.

The combined effects of caffeine and l-theanine in a 1:2 ratio have been proven to be optimal for cognitive performance and mood; which means that Thesis has a good base.

Furthermore, I welcome the transparency in their labels, which is not usual in nootropics – even in the most popular ones like Alpha Brain .

Here is the breakdown of each formula, and the dosages.

30-Day Thesis Nootropic Test and Results

As pictured above, I have the starter kit.

The kit includes four blends of your choice, each with six individually wrapped doses that are designed to be taken once daily. My kit contains the blends for Clarity, Creativity, Confidence and Motivation . As per the instructions, I’ll pick a blend, take it once daily for six days, with one day off. I’ll evaluate the results, then start the next blend.

A quick bit about me: large male, mostly sedentary with some high activity days, no chemical vices, mostly liquid diet as of late.

I’ll be taking each dose with food as recommended, likely with one our recommended meal replacement shakes such as Soylent, Huel , Ka’Chava or Rootana .

Week 1 – Thesis Clarity Review

This blend consists of four pills, a lot to swallow. The goal for Clarity to improve and maintain focus and attention .

Early on, the effects were pretty noticeable . I did feel more energized when performing physical activity. Also, I did feel more “locked in” when I had to focus, in particular with games that require high execution and fast reactions.

On the flipside, days when I didn’t have much going, I didn’t notice much of a difference. I didn’t feel need to do more, and without something to intently focus on, they may as well be water pills.

For similar effects, you could also try Optimal Nutrition’s nootropic Focus coffee , a more fun way to consume them.

Week 2 – Thesis Motivation Review

Only three pills in this blend, so a bit easier to take.

Motivation is designed for task completion and focuses on reducing procrastination and stress. I did manage to stay focused on my current diet, though I feel that would have happened with or without these pills.

This one really didn’t do it for me. I felt like my sleep was noticeably worse during the week of taking this week.

Week 3 – Thesis Creativity Review

Back to four pills with this one. The highlights of this blend focus on learning, memory and cognition.

At times I felt scattered, like I had to be doing something, which can be detrimental if you need to focus on a set of tasks. But I can see if I needed to innovate something, how this can help, being able to cycle through thoughts and ideas quickly.

Seemingly no ill side effects too. Pleasantly surprised considering I’m not at all very creative.

Week 4 – Thesis Confidence Review

Three pills, with two of them dark. Reminds me of hamster pellets. Moving on….

Of all the blends, I felt the effects of this one the fastest, usually within about 30 minutes, as opposed to an hour or so like the others.

It felt like a spike and gradual leveling off of the effects, which felt less tailored than the others. I didn’t necessarily expect to feel more confident, but it was just harder to pinpoint this one.

It worth noting that this could also be to the accrual effect of having taking nootropics for the past 30 days. Most of the best nootropics take a while to showcase all their positive effects, as there’s a build up period.

“As long as I can remember, people thought I was stupid, lazy, or unmotivated. I started to believe it. In school, I would read the same page over and over again, without absorbing anything. At 16, I dropped out of high school and went to work at a sandwich shop. Fast-forward ten years — I scored in the 99th percentile on the GMAT and earned Master’s degrees from Yale and INSEAD. Nootropics turned everything around for me and helped me form the positive habits that I built my success on. Once I balanced my brain chemistry, I could perform like never before. Dan Freed

Thesis supplement can be purchased as a single box, or part of an ongoing subscription. You choose which blends you prefer and they are shipped to you monthly.

• One time purchase (30 days) – $119
• Subscription purchase (30 days) – $79 per month

Shipping is only within the US, and is free via USPS First Class Mail.

Are Thesis Personalized Nootropics Worth It?

Regarding the price, Thesis offers a very competitive offering when compared to the best Nootropics like Hunter Focus .

In particular when you use the subscription discount, at $2.33/serving I feel like Thesis offers you a very tempting offer. A personalised nootropic blend is a very unique proposition and finding what works best for you can be hard.

Thesis makes this easier, which is already a big plus, and you could see bigger benefits than with other competitors.

Taken that into consideration, I believe that Thesis nootropics are worth it for those considering regular use to improve cognitive function and long-term mental health.

Thesis can only be bought from their own website, which means that there are no Amazon Thesis reviews to look at.

That said, reviews on their site are overwhelmingly positive. Not all products seem as effective, as discussed in our tests, and Creativity and Clarity seem to be the least liked. On the other hand users liked Motivation and Confidence the most, unlike me.

This remarks the importance of choosing the right blend.

I’m going to be honest with you, I was skeptical but I started a new job so I thought maybe it could help.Within a half hour of the first time taking it I saw immediate results.I’m more alert and focused than I’ve been in years.I’m so happy I found Thesis as it has been life changing for me so far. Elliot S, 5-star

I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work. Thank you for making such an amazing product. Debbie M, 5-star

If you’re new to nootropics, we can guide you to the blends we believe will work best for you based on your lifestyle and goals. You can make adjustments to these blends based on what works best for you.

Our Starter Kit is designed so that you can try multiple formulations to identify which nootropics work best with your unique brain chemistry. Each week you will sample one of your recommended blends, and record how you respond. Things to note would include increased productivity, decreased procrastination, enhanced focus and any changes in your routine At the end of the first month, you should have a good idea as to which blends work most effectively for you. These will be the blends you will continue with in your next month.

You will receive four distinct nootropic formulations totaling a four week supply, an instructional booklet, and access to our team of nootropic experts and wellness coaches to help you set and achieve your goals! You will also receive email messages with additional instructions to make the most of this exploratory month.

We offer the most advanced nootropic system available, to find the exact compliment for your specific brain chemistry and desired areas of focus. Our innovative Starter Kit allows you to experience multiple formulations, and determine what works best. Our process is complex because we’ve found that it yields the best results in the shortest amount of time. If we could formulate one pill that would work for everyone, we would! Because the human brain is deeply complex, that is just not possible.

Depending on your genetics and experience with nootropics, the effects can be felt in as little as 30 minutes after taking each blend. Nootropics have the most impact when taken on an empty stomach, just after waking from a normal night of rest. Some people may need a few days of consecutive use to feel the effects of the nutrients.

Verdict: Thesis Nootropic Review – 4 Weeks with Noticeable Effects

This has been a long review, probably my longest as you have to nootropics time in your routine and in your system to truly reap the benefits.

I find the approach that Thesis is taking to be a sound one. While some may be annoyed or turned off by the initial quiz, it’s certainly a necessary step in the overall process of finding which blends work for you, and which you should avoid. Also, without it, it would be a one size fits all product, and there are plenty of those already on the market.

Personally, I thought that Clarity and Creativity did the most for me . They each had noticeable effects that were largely in line with what was expected. Motivation and Confidence I wouldn’t have again, as Motivation seemed to to correspond with poor sleep and Confidence just didn’t provide enough of a benefit for me.

There are a couple of others in Energy and Logic that I did not try but would like to…and that alone may bring me back. Plus, I much rather have caffeine free, and I think it’s cool that’s even an option.

Bottom Line – If serious about adding nootropics to your routine, Thesis offers a great way to find what’s best for you.

Thesis Nootropics

Ingredients

Effectiveness, nootropic blend.

• Personalized nootropics for each goal
• It was effective when tested
• Clarity was our favorite
• Short and long-term positive effects
• There are more comprehensive blends out there that do all
• Only in the US

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Thesis Nootropics Review 2024: Honest Thoughts + Am I Still Buying?

• Last updated: August 28, 2024

About Dr. Steve Kim, MD

Physician Advisor

After using Thesis nootropics for more than a year, for me, the higher price point is definitely worth it for the cognitive benefits I’ve experienced. Specifically, I’ve noticed that I am not feeling overwhelmed as often as I was prior, and I am able to focus and complete tasks with more ease.

Thesis Overview

• Price:  $119 for one-time purchase or $79 with subscription
• Helps With:  Cognitive function, including motivation, memory, focus, and more
• Side Effects:  Headache, stomachache, and more
• Safety: Made with ingredients that are Generally Recognized As Safe (GRAS) by the FDA or have passed Phase III clinical trials
• Dietary Information:  Vegan, and made without gluten, eggs, and nuts

Thesis offers a variety of  nootropics, also called “smart drugs,” which are medicinal substances that improve cognitive function, specifically memory, thinking, and learning. While some prescription nootropics are FDA-approved, Thesis is not regulated by the FDA and is available over-the-counter (OTC). However, their ingredients are third-party tested and they only use ingredients that are either Generally Recognized As Safe (GRAS) by the FDA or have passed through Phase III clinical trials. 

I’ve been taking Thesis for over a year now, about six times a week, and I’ve noticed some significant improvements in terms of how often I feel overwhelmed, as well as my ability to focus and stay on task. While I know Thesis won’t work well for everyone, these nootropics agree well with me and I’ll continue using them to help boost my productivity, focus, and more. 

In this article, I’ll delve into my experience using Thesis nootropics, as well as discuss their potential benefits, side effects, and more.

• Custom blends
• Personal coaching / support by nootropic experts
• No proprietary blends (AKA no hidden ingredients!)
• Caffeinated or noncaffeinated formulas
• Effective ingredients
• No free trials
• Relatively high monthly cost

My Experience Taking Thesis Nootropics

I’ve been loving Thesis since I started using their products, specifically the Clarity, Creativity, Logic, and Energy blends, over a year ago. While there’s no nootropic that’ll offer you the same potency you’d get from Adderall, or other prescription stimulant medications, I’ve found Thesis to work surprisingly well for my needs.

When using them 6 times a week, they have offered notable improvements in how well I’m able to focus and stay on task. In practice, this usually looks like a clearer mind and an improved ability to maintain a relaxed state of mind while completing various tasks. As someone who feels overwhelmed fairly often, this is a welcomed change of pace.

With their Clarity and Creativity blends, in particular, I just feel leveled out. I’m able to sit down and work, without feeling like I’m just hopped up on too much caffeine, a feeling that really makes me uncomfortable. 

In the world of nootropics, where certain products don’t seem noticeable whatsoever, it cannot be overstated just how awesome my experience with Thesis has been.

Benefits of Thesis

As a customer, you’ll have the opportunity to speak with their coaches at any time. I have reached out on a few occasions, just to talk about the fascinating world of nootropics. In particular, I have had amazing conversations with one of their neurologists, Cindy. It truly is nice to speak with other individuals who are as fascinated with the science behind nootropics as I am.

Another aspect of Thesis that I really respect is that they clearly publish not only which ingredients they include, but also the exact amounts of each ingredient. This matters because it allows consumers to actually cross-check the research behind the ingredients/dosages, an unfortunate rarity in the supplement space.

•  6 custom blends, each with unique effects that may work well for many individuals
• Personal coaching/support from nootropic experts
• No proprietary blends (hidden ingredients)
• Caffeinated or non-caffeinated formulas
• Effective ingredients that are backed by science and are third-party tested
• Available OTC
• Not FDA-approved
• Relatively high monthly price, which may not work for everyone

How Does Thesis Work?

You’ll start by filling out a questionnaire on their website, which should only take a few minutes. Once you’re done with the survey, Thesis’ algorithm will run through its millions of data points to predict which of their blends may work best for you. 

Once you place your order, either as a one-time purchase or as a subscription, you’ll be shipped your blends.

Per the instructions, you’ll begin taking your blends and note how you feel in the included daily journal. This will help your track whether your blends are the right fit for your needs or if they need to be adjusted. You’ll also be able to speak with one of their coaches at any time for additional support. 

Related reading: Stasis Supplement Review – Our Research, Testing, and Impressions

Thesis vs. Alternatives

 We’ve created this comparison table to pit Thesis up against Onnit and Mind Lab Pro , two other popular nootropic brands.

Thesis Nootropics Side Effects

The ingredients in Thesis may lead to side effects in some individuals, including: 

• Stomachache
• Signs of an allergic reaction

If you experience any prolonged discomfort, stop taking Thesis and reach out to your healthcare provider. Seek urgent medical care if you experience serious symptoms of an allergic reaction.

The Verdict: Are Thesis Nootropics Worth It?

Thesis offers a complete toolkit of nootropics that are tailored to your needs, in addition to ongoing expert support. Unlike other nootropics, which may include unnecessary or hidden ingredients, Thesis only offers what you need with their six unique blends that focus on supporting logic, energy, creativity, clarity, motivation, and confidence. Once you find the blend or blends that work for you, you can opt into a subscription and save on costs. 

While the monthly cost may be on the higher side, the ability to select only the blends you need, instead of opting for a nootropic that may include ingredients that are unnecessary for your particular needs, is definitely a major benefit of opting for this provider over others.

Keep in mind that Thesis will not feel as potent as prescription stimulant medication and that certain blends may lead to side effects, like gastrointestinal problems or headaches, in some. It’s always best to speak with your healthcare provider prior to trying Thesis to ensure that it is safe for you to do so.

Thesis will not be as potent as Adderall, a prescription medication. However,  Thesis , a type of nootropic or “smart drug,” may work well for some individuals in boosting cognitive function, focus, and more. 

Some nootropics can be used every day. However, it’s best to follow the specific’s products instructions, as well as speak to your healthcare provider about safe use.

Thesis  may be safe for some individuals to use. According to the company, they only use ingredients that are either classified as Generally Recognized As Safe (GRAS) by the FDA or that havve passed through Phase III clinical trials. However, it’s always best to speak with your healthcare provider prior to trying Thesis to ensure that it is safe for you to use.

Thesis does not offer free samples, however, they do offer a no-questions-asked refund. 

Thesis offer caffeinated and caffeine-free formulas.

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Thesis Nootropics Review

Nootropics fan and expert James Dixon examines this personalized supplement in our Thesis Nootropics review. Find out how he rates it after testing it below…

Last Updated:

August 6, 2024

Written by James Dixon – fact checked by Jason M & the editorial team

James Dixon is one of the key players in the SOMA Analytics’ team. He is a personal trainer and is educated to Masters level in Philosophy. He is a published author and is a keen advocate of high quality nootropic supplements.

This article complies with the SOMA Analytics editorial policy. Full details of which can be found here

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Nootropic supplements – so called ‘smart drugs’ – are all the rage. They represent a rapidly expanding corner of the supplement market and have had genuinely life-altering effects on many, many users – myself included.

They’re not actually ‘drugs’ as you would think of them. This isn’t medication we’re talking about, here. Rather, these supplements are compounds of natural ingredients designed to work together to boost your cognitive health and brain function .

A good nootropic should help you feel smarter… which is a bold claim. There is something to it, however.

Nootropics should aid your focus, learning skills, memory, and creativity . They should reduce brain fog, anxiety, and lethargy , replacing them with clarity, calm, and plenty of low-key energy.

If you struggle with any of these symptoms, there is a good chance that you could do with a quality nootropic, which is exactly what we’re looking at today. Though perhaps not the best of the best, Thesis Nootropics offer a range of products that are all intelligently crafted and, to a degree, fairly personalized.

And when I say they aren’t the best of the best, this doesn’t mean much. The nootropic market is crowded. There are a couple of standout items out there – NooCube springs to mind. Playing second fiddle to these is still a large accomplishment.

Let’s dive in and take a full look as I dig in to this Thesis Nootropics review.

Quick Verdict: Thesis Nootropics

Thesis Nootropics have a great range of different nootropics aimed at different needs. They also have an excellent nutritional coaching system to support you.

However, the reality is that most people won’t really gain from this additional 5%. Products such as NooCube offer greater value for money with similar nootropic benefits.

Introducing Thesis Nootropics

As above, Thesis Nootropics are smart drugs. They offer high-quality nootropics that are designed to help with various aspects of your cognitive health and function. Their products all contain top-shelf ingredients all proven to help your brain to work optimally.

They also do something a bit different. Where most nootropics – and most other supplements, for that matter – offer you the same over-the-counter pills as they would offer anyone else, Thesis bring personalized supplements to bear.

Through their online store, you can fully personalize your nootropic options to make the most of your own specific needs and circumstances .

It’s really quite clever.

They started out as FindMyFormula.com before rebranding a few years back. So, although ‘Thesis Nootropics’ may seem like a newcomer to the market, they have actually been around for a long time.

They bring this pedigree to the fore with this product. With a customer base of over half a million users, they have proven themselves and then some.

The data they hold from their research into nootropics is peerless – I can’t think of anyone with better. And they use it well, crafting and re-crafting their formulae with proper, diligent science and data in mind.

The personalization process is actually quite straightforward too – at least, it is for the customer, which is always nice.

You start off by going to their website and taking their questionnaire. Don’t worry, it’s not all that comprehensive, asking for only basic information. There is no need to take any lab tests or divulge your medical history.

However, it’s enough for them to make a match for the nootropic blends that will best suit your needs.

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There are two ways to read this, of course. Either, it’s a non-invasive way to tailor your supplements, or it’s not a deep enough dive, so how well tailored can they really be?

I felt a little let down, here. When I came in being promised ‘personalized supplements’ I had higher hopes. Instead, it’s just sort of asking what you want and pointing you in the right direction.

It’s nice, it’s just not quite as revolutionary as the literature and branding suggest.

The next phase is good, though. They’ll send your shipment out to arrive within 1-3 business days .

However, they ask you to treat this as a sample; they invite you to try out a few different blends of theirs before picking it.

This data is fed back to their algorithm, further enhancing their future prescriptive capabilities. Again, you can read this cynically or not.

Either it’s a great way to search out what works best for you, or it’s doing their job for them and getting you to buy plenty of their products in the process… if their original diagnostics are that good, why do you then need to cycle through their catalog?

Except that they allow you to try up to four before committing to a longer-term formul a. Pair this with that original questionnaire and, cynicism on hold, you have an excellent and innovative product.

It helps you to refine your own choices without having to do the legwork, which can often take months, a lot of money, and a fair amount of trial and error.

The final part is my favorite part, and dispels much of my lingering cynicism…

As a Thesis customer, you are assigned a nootropics expert , a sort of coach and pharmacist in one. You can consult with them virtually at any time.

They can help you to further refine your nootropics regime, find ways to optimize your results, track your progress and wellbeing, and generally educate you by ably answering any questions you might have.

I love this. It takes Thesis to the next level – it’s less a supplement and more a course focused on wellbeing.

It’s not cheap, I’ll warn you now. A starter kit will go over a hundred dollars. A prescription will run to a monthly bill of around eighty.

This is roughly twice what you would pay for something like NooCube or Mind Lab Pro , supplements I consider to be the best of the best. It’s around four times what you could pay for a lower-end, albeit workable nootropic.

You’re presented with a choice, then: pay extra for the support and tailoring, or pay a far more reasonable amount for something that will still do the job incredibly well.

Why Choose Thesis Nootropics?

The benefits of Thesis Nootropics are fairly straightforward.

Firstly, Thesis shares the same benefits as any other good-quality nootropic supplement. They offer several blends (more on this below), which between them can improve your cognitive function from pretty much every angle.

You can boost your cognitive energy, improve your clarity, improve your memory and learning abilities, clear brain fog, improve your mood, reduce your stress levels, and boost your ability to focus, among other things.

This is all good. It’s what you’re looking for in a nootropic in the first place.

But, of course, the benefits go beyond this. The two main things you get from Thesis that set it apart and above most of its competition, are really very special.

Firstly, of course, you get the personalization mentioned above. This can be fantastic. Or it can be a little superfluous.

If you try something like NooCube, you will probably find it working for you. It may not be 100% scientifically optimal, but it will be 95% there for most of us.

However, if others haven’t worked for you, personalization may be a very good idea. You can really zero in on the aspects of your own cognitive health and function that you feel need improving.

Also, if you want to get that final 5% (figures not accurate, of course) and don’t mind parting with a little extra cash, Thesis can be well worth it. You will be as cognitively optimal as modern nootropic research can make you, which is no small thing.

Then there is the access to their experts . Again, this can be superfluous. How much do most of us really need to know about nootropics above and beyond what you can read in any good review or rundown? Just learn the basics, throw back a couple of NooCube capsules, and get on with your life.

But, again, it can be wonderful. This is where the extra price begins to seem really quite minimal.

Our Preferred Alternative To Thesis

Although we found Thesis Nootropics to include high-quality ingredients, the personalization for most people is not required and adds a lot of expense to an already pricey supplement.

We prefer NooCube, the nootropic taken by our tester and writer – thanks to its high-quality formula, high-impact results, and value for money cost.

Thesis Nootropic Ingredients

Thesis Nootropics offer several different blends, relatively personalized towards the individual, focused entirely on aiding different facets of cognition and brain health.

Given these differences, it’s no surprise that each blend contains a different list of ingredients – though there are of course some commonalities between them.

The Energy blend is one of their most popular. The formula is made to boost your energy levels whilst fighting fatigue and improving your mental stamina.

Next up, we have Thesis’ Clarity , which contains plenty of the ingredients I would expect to see in any good nootropic to maintain focus, support attention, and enter flow state – which is when you are achieving an optimal state of consciousness, fully immersed in a task and performing at your best.

Motivation is a bit of a funny one, as motivation is inherently a hard metric to either properly define or measure. However, in this context, motivation means a boost to willpower and productivity, and help in warding off procrastination.

Then we have Creativity , which is often misunderstood in nootropics. Being creative helps us think outside the box; stretch the imagination and come up with solutions to problems. This formula also works to improve verbal fluency and confidence. So what sounds like fandango initially could actually be incredibly beneficial on a day-to-day basis.

Finally, we have Thesis’ latest blend, Confidence . As you may well imagine, this leads to a boost in confidence!

Confidence’s ingredients all target stress, especially stress responses to insecurities, whilst promoting a feeling of self-assurance. It also aims to ‘soothe the nerves’, so that you can function calmly.

Edit: Thesis have since added Logic to their collection: perhaps their most closely linked to a classic nootropic, as it works to support memory, encourage deep thinking, and improve processing speed.

Ingredient Profiles

• Lion’s Mane Mushroom
• Camellia Sinensis Tea Leaf
• Dihydroxyflavone
• Agmatine Sulfate
• Panax Ginseng
• Ashwagandha Root
• Sceletium Tortuosum
• Ginkgo Biloba
• Theobromine
• Phosphatidylserine
• High DHA Algae
• Uridine Monophosphate
• Bacopa Monnieri
• N-Acetyl Cysteine
• Indian Trumpet Tree
• N-Acetyl L-Tyrosine
• L-Phenylalanine
• Methylliberine
• Vitamin B12
• Magnesium Bisglycinate
• Magnolia Bark
• Ashwagandha Leaf & Root

How to Use Thesis Nootropics

Nootropics are amongst the easier supplements to live with. There are no special timings or anything like that to hit, and the portions are all very manageable.

Thesis Nootropics fit this pattern nicely. For all of their different lines, simply take them in the morning, ideally when you first get up, on an empty stomach with a decent glass of water.

If you need a bit of an extra boost during the day (particularly if you’re going for the energy blend), feel free to take a second dose at lunchtime to see you through until the evening. This will ensure clarity and energy all day long.

Using Thesis Nootropics

I was quite sceptical of nootropics when I first heard about them in the early 2010s. They sounded too good to be true – over-the-counter supplements made from all-natural ingredients that can boost your brain health and cognitive function? No way.

Many are too good to be true. Plenty of nootropics out there don’t do anything above and beyond giving you a brief energy kick, and this is usually down to their caffeine content. You’d be better off having a cup of coffee or cheap caffeine supplement.

Thesis Nootropics are not too good to be true. They are good – very good, in fact – and highly workable.

I’m not entirely sold on them. I find them to be a bit gimmicky. They shouldn’t be gimmicky, of course – tailoring to your uses and offering coaching is no gimmick.

However, it’s just a little shallow to be truly tailored – they are simply giving you a selection of stacks, which many supplement stores offer (CrazyBulk, for instance).

And the coaching is perhaps a little superfluous for most people.

But the supplements themselves are good. They are well developed, well made, high quality, and will absolutely elicit the effects they claim in many, many people.

I got on well with them. I took their Energy blend first, which is always my priority (I’m always juggling seven or eight different projects at any time, so an energy boost will always be welcome!)

It did what it said it would. I found my focus improving and my energy lasting me through the day. I usually drink a lot of coffee, which tends to give me spikes and crashes. The spike wasn’t as high with the Energy blend, but nor was there any kind of crash.

I also tried Clarity, as I take a couple of prescription medications that can lead to a touch of brain fog. It cut through my brain fog well, lending me a great deal of clear-sighted cognitive energy. There was no coming round in the morning, no chugging espressos just to form a coherent sentence. Or, at least, I came round quicker and reduced my espresso intake.

I also wanted to know a bit about Thesis’ coaches, or whatever they call themselves.

I got in touch and was chatting to a woman with a highly relevant, impressive array of academic credentials just a few days later. She explained how the components in the blends I was trying worked and interplayed, and pointed me in the direction of a couple more that I might like to try.

The advice was kind of handy, though it wasn’t anything I would struggle to find out just from perusing their website. The information was interesting to a health and supplements nerd, but that was it. I can’t imagine it being in any way helpful. I can’t even imagine it being interesting to most people.

It’s not a good use of money (and you will be spending a lot of money on Thesis). The supplement is strong – the blends I tried were strong. But none of them gave me the kinds of results I have experienced whilst taking cheaper, better nootropics, namely NooCube – this is what I personally tend to take on an ongoing basis.

There is no harm in trying Thesis. They offer a one-month money-back guarantee, so you can get that hefty price tag (generally around $119) back again if you’re not satisfied.

I think you will be satisfied. Thesis is a satisfying product. It’s just not the best, and the best happens to be an awful lot cheaper.

Do also bear in mind that nootropics can cause side effects – Thesis’ blends are no exception. They can lead to blurred vision, high blood pressure, an accelerated pulse, circulation problems, and insomnia, though severe or long-lasting cases are rare.

Pros and Cons

Thesis pros.

• Personalized for optimal benefits.
• Comes with access to their experts.
• High-quality ingredients.
• Highly reputable company.
• Different blends for different uses/needs.
• Ability to try out different blends before committing.
• Easy to take.

Thesis Cons

• The personalization is a little shallow.
• It’s very pricey (about twice as costly as other leading nootropics).

Our Thesis Video Review

Thesis Nootropics are good. In fact, they are very good. The personalized aspect, whilst admittedly a little shallow, is still very welcome. I like it a lot.

As a bit of a supplements nerd, I also love the idea of being able to chat to an expert at any time – this really is a nice touch.

However, I can’t help but feel that it’s all a little superfluous. Most people know their own needs. A quick Google search will show you what nootropics will be best for you. If in doubt, go for a cover-all nootropic. I keep mentioning NooCube with good reason – it should do pretty much everything that all of Thesis’ blends do.

Then there is the price. You’re paying a lot for a good product with plenty of customer care involved. However, as above, the customer care is largely excessive. If you really want it – and I can see plenty of people wanting it, with good reason – then by all means fork out extra.

However, it’s just a little extravagant for most people.

For a month’s supply (at non-subscription prices), you can buy around three months’ worth of NooCube. For this, you’ll be getting just about the best nootropic on the market with no extra legwork – just simply take it each morning, save some money, and get on with your life with your cognitive health in near perfect shape.

Verdict: Thesis Nootropics

The reality is that most people won’t really gain from this additional 5%. Alternative products such as NooCube offer far greater value for money with similar (if not better) nootropic benefits.

This article was written by: James Dixon – SOMA Analytics PT, Nutritionalist & Published Author

James Dixon is one of the key players in the SOMA Analytics’ team. He is a personal trainer and is educated to Masters level. He is a published author and is a keen advocate of high quality nootropic supplements. James enjoys helping others to reach their peak both physically and mentally and believes that expressing his knowledge through his writing is an effective way to positively impact the wellbeing of others on a larger scale.

Latest Updates:

✎ July 25, 2024: Updated product images, resized and repositioned. Checked links and offers. Added additional Logic product which has since been added to the Thesis range. Checked ingredients and amended where required. Added updated image of quiz questions. Added entire ingredients profile section for clarity. Reformatted areas such as Pros & Cons.

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Thesis Review: Are Personalized Nootropics Legit?

Calloway Cook Calloway Cook is the President of Illuminate Labs and has reviewed over 1,000 clinical trials. See full bio . , Author | Taylor Graber MD Taylor Graber is a Medical Doctor (MD) and a practicing anaesthesiologist. He's also an entrepreneur who runs a health and wellness startup. See full bio . , Medical Reviewer Last updated: Nov 05, 2023

Calloway Cook Calloway Cook is the President of Illuminate Labs and has reviewed over 1,000 clinical trials. See full bio . , Author

Taylor Graber MD Taylor Graber is a Medical Doctor (MD) and a practicing anaesthesiologist. He's also an entrepreneur who runs a health and wellness startup. See full bio . , Medical Reviewer Last updated: Nov 05, 2023

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

Illuminate Labs has a team of medical experts including doctors and Registered Dietitians who are assigned to review the accuracy of health claims and medical research summaries based on the relevancy of their expertise to the article topic.

The focus of our articles is to share our opinion on the potential efficacy and safety of health trends and products.

T hesis is a wellness brand that sells personalized nootropics. The brand sells supplements with unique names like “Creativity” and “Motivation,” and claims that their individualized products are “based on your unique brain chemistry.”

But is there legitimate research backing personalized nootropics or is this just a marketing spin? Why does the brand ask for so much personal data? Are their supplements well-formulated? And how do real users rate and describe the effects of Thesis?

In this article we’ll answer all of these questions and more as we share our concerns about the marketing practices and health claims of Thesis.

We’ll also analyze the ingredients in one of their formulations based on medical research to give our take on whether or not it's likely to be effective. We’ll share customer reviews of Thesis nootropics including some from individuals with ADHD.

Is the “Personalized” Approach Fake?

The branding around Thesis is of “personalized nootropic formulas,” however this may be entirely untrue.

We submitted test answers into the health intake form of their site, along with a fake email, and after submitting all of this information we were brought to their “Starter Kit” landing page which is accessible at this link .

If you access the above link in a new window, the products suggested are the exact same, which suggests that Thesis is really collecting sensitive customer health data based on the guise of “personalized” supplements, while providing no additional value, which is a highly questionable marketing approach in our opinion.

The concept of “personalized nootropics” doesn’t even make sense, because the manufacturer would have to literally formulate and package them when a customer placed an order, unique to each customer’s order which is highly unlikely. It would make no business sense for a company to formulate millions of unique products and would be logistically impossible.

It appears that Thesis simply recommends some of their supplements to consumers based on their needs, which is not a “personalized nootropic formula,” it’s a personalized recommendation which literally any brand could offer.

This leads us to our second concern about this brand.

Rather than simply selling supplements, they require users to complete a questionnaire which asks a number of sensitive health questions. 

As shown above, the brand requires users to answer questions about their gender identity and their alcoholic intake in their health quiz. What does this have anything to do with nootropics, and why would any user share this data with a random supplement startup?

We would recommend avoiding this brand based on these marketing and data collection practices alone, but in the next section we’ll analyze the formulation of one of their products.

Ingredient Analysis

Thesis’ “Motivation Formula” contains five active ingredients: l-phenylalanine, Dynamine, vitamin B12, forskolin and artichoke extract.

L-phenylalanine is an amino acid that Thesis describes as supporting mood, attention and motivation, however these claims are uncited and we can’t find any medical evidence supporting them. 

Most of the clinical research we found on this ingredient involves obesity, with this clinical trial finding that l-phenylalanine may increase the sense of fullness and decrease calories consumed in overweight individuals, but only at a dose 20x that in Thesis’ supplement.

Dynamine is a trademarked form of methylliberine, which is a chemical compound that can be isolated from coffee beans and tea. Thesis claims that this compound “supports alertness” but this claim is uncited and we can’t find any medical evidence supporting it.

The manufacturer of this ingredient is a company called Compound Solutions, and the company even states on their website that this ingredient is “typically used in combination with caffeine and TeaCrine,” because all three of the clinical trials that the manufacturer cites on their website use Dynamine in combination with either caffeine or TeaCrine.

However, there is no caffeine or TeaCrine in Thesis Motivation.

Vitamin B12 is often included in nootropic formulations, but we’re unsure why. As we referenced in our review of another nootropic supplement called Noocube which also contains this ingredient, we can’t identify any medical evidence that vitamin B12 improves cognitive function in healthy adults without a vitamin B12 deficiency.

Forskolin was shown in an animal study to reduce memory loss, but the lowest dose used was equivalent to over 200% of the human-equivalent dose in Thesis. We can’t identify any clinical trials with human trial participants proving this compound to be an effective nootropic.

Artichoke extract is the final active ingredient, and Thesis claims that this ingredient “supports blood flow and promotes stress management.” These claims are uncited and we’re unclear on why this ingredient would be included in a nootropic formula, as even the stated health claims do not reference an explicit improvement in cognitive function.

Thesis fails to publish inactive ingredients for Motivation, which is an important consumer safety concern.

Overall we do not consider Thesis Motivation likely to be effective for improving cognitive function or productivity as we are unable to identify a single active ingredient that we would consider effective at the given dose, based on a review of clinical studies.

We do not recommend this supplement or brand, and consider this product to be one of the worst nootropic formulations that we’ve reviewed on Illuminate Health. Most nootropic supplements we review at least contain one effectively-dosed active ingredient.

We Tried Thesis Ourselves

One of our product testers named Matt Donnelly tested Thesis. Here's his experience:

I spent the month trying out the starter pack, which included CLARITY, MOTIVATION, LOGIC, and MOTIVATION.

Of the four, the only one that seemed to have any positive effect was LOGIC. It's good for “Research projects” and “Complex problem-solving” according to the packaging.

I was hoping for good results because I had been sidetracked from creative projects. It seemed like this one may have contributed to more focus overall and focused attention.

On some days I got very tired a few hours after taking the capsules, and needed to lie down in the afternoon.

There are three or four pills in each packet. It seemed to me like a lot to consume on a daily basis, and the pills are large so they could be challenging to swallow.

Overall, I would rate Thesis 3/10 and I wouldn't purchase this product again.

Thesis User Test

A YouTube creator named “LUKAS YAN” reviewed Thesis nootropics and shared his thoughts on whether or not the supplements improved his physical and mental energy:

Will Thesis Nootropics Cause Side Effects?

Thesis Nootropics do not appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not they’re likely to cause side effects. However, we can make an educated guess based on their formulations.

Most of the active ingredients in Thesis supplements appear to be safe and well-studied. We don’t have access to the full set of the brand’s supplements because instead of transparently posting all product pages they rely on the “individualized” marketing.

Our concern in regard to side effects is that the brand fails to clearly publish inactive ingredient information, and some inactive ingredients can cause side effects.

We hope that in the future Thesis publishes inactive ingredients in the same section where active ingredients are published for each supplement they sell. This is important for consumer safety.

Our Clean Nootropic Picks

Mind Lab Pro   by Performance Lab is our top premium nootropic pick.

This is the first Illuminate Labs Certified supplement, and   has been shown to be effective for short-term cognitive improvements in   two   clinical   trials   published in peer-reviewed journals.

Performance Lab MCT Oil   is our top food-based nootropic pick.

MCT oil  is derived from coconut oil, and  improved memory recall by 20% in adults  in a 2022  meta-study .

Illuminate Labs Ginkgo Biloba Extract   is our top herbal nootropic pick.

A  medical review  published in the  Psychopharmacology  journal  found that ginkgo biloba supplementation improved attention and cognitive performance in healthy, young adults.

Is Thesis Effective for ADHD?

We don’t recommend using Thesis supplements to treat any specific health condition.

There are several TikTok reviews from individuals with ADHD who tried Thesis supplements.

A TikTok user named Syd shared her experience using Thesis while having ADHD:

@sydneydelucchi Lets try @takethesis ! #nootropics #nootropicsforadhd #adhd ♬ original sound - Syd 🦋

A TikTok creator named Mike Cribbs shared her experience:

@mikacribbs Replying to @adrienne here are my initial thoughts using @Thesis 💙🩵 #takethesis #nootropics #thesis ♬ Fukashigi no Carte Lofi Hiphop (Bunny Girl Senpai) - bvyunx

We disagree with the way Thesis markets their products, and we recommend that consumers avoid giving sensitive health data to dietary supplement startups unnecessarily.

The one Thesis supplement that we analyzed based on its active ingredients, called Motivation, was underwhelming. We were unable to identify any effectively-dosed ingredients based on a review of medical research, and the brand fails to clearly publish inactive ingredient information or cite the health claims made about their ingredients.

We do not recommend Thesis supplements although we don’t consider it likely that the supplements will cause side effects.

Some TikTok users with ADHD who tried Thesis supplements had relatively negative feedback.

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The Science Behind Nootropics – Do They Actually Work?

Herbal brain boosters are on the rise, but does science back them up here's some truth behind nootropics and their alleged benefits..

Sometime in 2024, I started getting ads in my Instagram feed from a supplement company called Thesis. The ads generally featured good-looking, fashionable people telling neat, 30-second stories about how the supplements had solved their chronic procrastination, indecision, or distractibility. Many of the evangelists were identified as high-achievers in their respective fields — a Ph.D. neuroscientist, a CEO, or a surgeon.

I’d be lying if I said that the ads weren’t compelling. As a digital journalist, my working life is constantly mediated by my computer screen. That same screen is a gateway to a functionally infinite amount of information, news, and entertainment. And, over the years, the internet has slowly harnessed more and more of my waking hours on and off the clock. It’s a reality that, at times, leaves me feeling overstimulated and paralyzed.

Many other people have had a similar experience. Over the past decade, young people have experienced an increasing amount of psychological distress , and people have been diagnosed with ADHD at higher and higher rates .

Nootropic supplement companies pitch an attractive solution. What if you could take a pill (or powder or gummy candy) that would make your brain function better in our technology-mediated world? Something that would help you focus on what is important, remember the right details and block out the noise. The nootropic industry is already worth more than $2 billion and is expected to double in size in the next decade, according to one report .

But, unlike prescription nootropics like Adderall or Ritalin, the U.S. Food and Drug Administration doesn’t highly regulate nootropic supplements. In many cases, American consumers must rely on the companies they buy from for information.

Testing and Research on Nootropics

Most of the ingredients found in nootropics have been studied to some extent. Thesis, the company that popped up in my Instagram feed, includes caffeine and L-theanine in most of their products. Research has reported that these two compounds might quicken your reaction time and boost your ability to process visual information and remember numbers .

Another common nootropic ingredient, Ashwagandha root, was shown to improve cognitive flexibility, visual memory, and reaction time in a study on 43 healthy Americans.

Other nootropic components, though, have far less evidence to back up their efficacy. Alpha-GPC, a common nootropic ingredient, was shown to mitigate drug-induced amnesia in rats in a study from the 1990s. Yet, subsequent studies on the cognitive effects of the chemical on healthy people have yielded little to no positive results .

The evidence for the efficacy of most nootropic ingredients lies in a gray area somewhere between hearsay and the robust clinical trials used to approve pharmaceuticals. There’s almost always a reason to be hopeful. Yet, there’s almost never enough evidence to characterize the effects completely or with conviction.

Read More: Does Neuriva Work and Can It Really Help the Brain?

The Nootropic Company Thesis

By his own admission, Thesis founder Dan Freed always struggled with focus.

“I remember how painful it was. It’s seared into my memory,” Freed says.

Sitting in a classroom was so painful, that Freed dropped out of high school and embarked on a career in the service industry. According to Freed, he eventually worked his way up to a position as a station chef at a 3-star Michelin restaurant. But, after a decade in the industry, he was burnt out and decided to study business management. His attention problem hadn’t improved much over the years, and he was desperate to fix it.

According to Freed, this is when he started experimenting with Nootropics. He read everything he could find on the subject and developed his own proprietary blend of powders, mushrooms, and pills. He credits the supplements with earning him a high score on the GMAT and a spot in a master’s program with the Yale School of Management.

Thesis’ business model is built around Freed’s early experiments with nootropics. The company encourages users to test a number of its six proprietary blends before settling on the one that works best for them.

“We created this data-driven approach to essentially finding the right ingredients for each individual to unlock their potential,” Freed says.

Read More: Strange Side Effects From Supplements and What You Need to Know

A Quasi-Scientific Approach

According to Freed, each ingredient in Thesis products goes through an internal review process that takes months to complete.

First, the company does a literature review of peer-reviewed research on the compound. Second, Freed tries it himself (this step hasn’t changed since the early days of powders and pills). Third, willing employees, friends and family members give it a shot. Finally, Thesis conducts “beta testing,” a randomized test on around 50 to 200 people, which Freed says is designed to mimic a crossover design that might be conducted on a prospective pharmaceutical.

These four steps roughly mirror the first two phases of the clinical trials of pharmaceuticals seeking FDA approval . Of course, there are third and fourth phases to a full clinical trial. Thesis stops after two. The company is allowed to do this because, technically, it is selling dietary supplements, not drugs. You can find a statement like this at the bottom of practically any nootropic company selling to Americans:

“The products and information on this website are not intended to diagnose, treat, cure or prevent any disease. The information on this site is for educational purposes only and should not be considered medical advice…”

The FDA issues a few warning letters a year to nootropics companies that use overly prescriptive language or forget to include a disclaimer. Thesis has not received one.

Freed argues that the lower bar for supplements like the ones that Thesis sells is actually advantageous for consumers. The nootropics industry can find ingredients faster and with far less investment than the pharmaceutical industry.

“The question I get asked the most is essentially, ‘do nootropics work?’” Freed says. “The question I think most people should be asking is, ‘which nootropics work for me?’”

Freed has so much conviction in his products, that he says he is working to find researchers to take Thesis blends through full clinical trials. But, until that day, customers will have to decide for themselves if the evidence is enough to go on.

Even after reporting this story, I’m unsure how I feel about nootropics. On the one hand, none of the ingredients seem to be harmful (except to your wallet), and the idea of taking a pill to make my brain work better is still tantalizing. On the other hand, simple things like sleeping and eating well have even more evidence to back up their efficacy on cognitive health. For now, I think I’ll set up a Google Scholar Alert and keep following the news.

Read More: Memory-Boosting Supplements Could Lack Compounds and Contain Bacteria

Article Sources

Our writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:

Psychological Medicine . Trends in self-reported psychological distress among college and university students from 2010 to 2018

Missouri medicine. ADHD Diagnostic Trends: Increased Recognition or Overdiagnosis?

Allied Market Research. Nootropics Supplement Market Size, Share, Competitive Landscape and Trend Analysis Report, by Type, by Product Type, by Distribution Channel : Global Opportunity Analysis and Industry Forecast, 2023-2032

Biological Psychology. The effects of l-theanine, caffeine and their combination on cognition and mood

Journal of Ayurveda and Integrative Medicine . Efficacy of Withania somnifera supplementation on adult’s cognition and mood

Pharmacology Biochemistry and Behavior . Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine

Journal of the International Society of Sports Nutrition . The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility

FDA.gov. Step 3: Clinical Research

FDA.gov. Warning Letter

Gabe Allen is a Colorado-based freelance journalist focused on science and the environment. He is a 2023 reporting fellow with the Pulitzer Center and a current master's student at the University of Colorado Center for Environmental Journalism. His byline has appeared in Discover Magazine, Astronomy Magazine, Planet Forward, The Colorado Sun, Wyofile and the Jackson Hole News&Guide.

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