research paper topics about diabetes

357 Diabetes Essay Topics & Examples

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🏆 Best Diabetes Essay Examples & Topics

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• Adult-Onset Type 2 Diabetes: Patient’s Profile Any immediate care as well as post-discharge treatment should be explained in the best manner possible that is accessible and understandable to the patient.
• Living with a Chronic Disease: Diabetes and Asthma This paper will look at the main effects of chronic diseases in the lifestyle of the individuals and analyze the causes and the preventive measures of diabetes as a chronic disease.
• Leadership in Diabetes Management Nurses can collaborate and apply evidence-based strategies to empower their diabetic patients. The involvement of all key stakeholders is also necessary.
• PDSA in Diabetes Prevention The second step in the “Do” phase would be to isolate a few members of the community who are affected by diabetes voluntarily.
• Nursing Care For the Patient With Diabetes The right diagnosis of a patient’s condition also helps in the administering of the right medication. In this case, the doctor would keep the goal of administering the right medication to the patient.
• Diabetes Mellitus: Symptoms, Types, Effects Insulin is the hormone that controls the levels of glucose in the blood, and when the pancreas releases it, immediately the high levels are controlled, like after a meal.
• Type 2 Diabetes as a Public Health Issue In recent years, a steady increase in the incidence and prevalence of diabetes is observed in almost all countries of the world.
• Diabetes: Disease Control and Investigation The second type of diabetes is Type 2 diabetes. This is a condition that leads to the development of type 1 diabetes.
• Gestational Diabetes: Child Bearing Experience Insulin resistance in GDM is likely to be the result of a combination of lifestyle factors and the insulin-desensitizing effect of chorionic gonadotrophins.
• Nursing Diagnosis: Type 1 Diabetes & Hypertension The nursing diagnosis based on the identified and primary problems are, “Risk for injury related to hypoglycemia, ‘Risk for Unstable blood glucose level related to lack of adequate management of hypoglycemia evidenced by decreased blood […]
• Nursing Care Development Plan for Diabetes and Hypertension In addressing the first nursing diagnosis, the main aim of the nursing interventions will be to prevent the development of secondary hypoglycemia by increasing blood glucose levels.
• Diabetes Management and Evidence-Based Practice Diabetes is a state of glucose intolerance that requires the management of blood glucose. Good glycemic control ensures that the level of glucose in a diabetic patient is maintained at levels similar to that of […]
• Case Study of Patient with DKA and Diabetes Mellitus It is manifested by a sharp increase in glucose levels and the concentration of ketone bodies in the blood, their appearance in the urine, regardless of the degree of violation of the patient’s consciousness.
• The Nature of Type 1 Diabetes Mellitus Type 1 diabetes mellitus is a chronic autoimmune disease that has an active genetic component, which is identified by increased blood glucose levels, also known as hyperglycemia.
• Counseling and Education Session in Type II Diabetes Patients will be educated about the glycemic index and its effect on their blood sugar Patients will learn to count their carbohydrates. Patients will set up their goal and the timeframe to achieve it.
• Health Nursing and Managing Diabetes The practice will equip more patients with the best ideas and initiatives to deal with diabetes. The completed study will provide the best practices and evidence-based ideas to help patients with diabetes type II.
• Gestational Diabetes in a 38-Year-Old Woman The concept map, created to meet B.’s needs, considers her educational requirements and cultural and racial hurdles to recognize her risk factors and interventions to increase her adherence to the recommended course of treatment.B.said in […]
• Type 2 Diabetes Mellitus and Its Implications You call an ambulance and she is taken in to the ED. Background: Jean is still very active and works on the farm 3 days a week.
• Development of Comprehensive Inpatient and Outpatient Programs for Diabetes Overcoming the fiscal and resource utilization issues in the development of a comprehensive diabetes program is essential for the improvement of health and the reduction of treatment costs.
• Healthcare Cost Depending on Chronic Disease Management of Diabetes and Hypertension A sufficient level of process optimization and the presence of a professional treating staff in the necessary number will be able to help improve the indicators.
• Improving Glycemic Control in Black Patients with Type 2 Diabetes Information in them is critical for answering the question and supporting them with the data that might help to acquire an enhanced understanding of the issue under research. Finally, answering the PICOT question, it is […]
• Shared Decision-Making That Affects the Management of Diabetes The article by Peek et al.is a qualitative study investigating the phenomenon of shared decision-making that affects the management of diabetes. The researchers demonstrate the racial disparity that can arise in the choice of approaches […]
• Managing Obesity as a Strategy for Addressing Type 2 Diabetes When a patient, as in the case of Amanda, requires a quick solution to the existing problem, it is necessary to effectively evaluate all options in the shortest possible time.
• Tests and Screenings: Diabetes and Chronic Kidney Disease The test is offered to patients regardless of gender, while the age category is usually above 45 years. CDC1 recommends doing the test regardless of gender and is conducted once or twice to check the […]
• Obesity Management for the Treatment of Type 2 Diabetes American Diabetes Association states that for overweight and obese individuals with type 2 diabetes who are ready to lose weight, a 5% weight reduction diet, physical exercise, and behavioral counseling should be provided.
• COVID-19 and Diabetes Mellitus Lim et al, in their article, “COVID-19 and diabetes mellitus: from pathophysiology to clinical management”, explored how COVID-19 can worsen the symptoms of diabetes mellitus.
• The Importance of Physical Exercise in Diabetes II Patients The various activities help to improve blood sugar levels, reduce cardiovascular cases and promote the overall immunity of the patient. Subsequently, the aerobic part will help to promote muscle development and strengthen the bones.
• Diabetes Education Workflow Process Mapping DSN also introduces the patient to the roles of specialists involved in managing the condition, describes the patient’s actions, and offers the necessary educational materials.
• Diabetes: Treatment Complications and Adjustments One of the doctor’s main priorities is to check the compatibility of a patient’s medications. The prescriptions of other doctors need to be thoroughly checked and, if necessary, replaced with more appropriate medication.
• The Type 2 Diabetes Mellitus PICOT (Evidence-Based) Project Blood glucose levels, A1C, weight, and stress management are the parameters to indicate the adequacy of physical exercise in managing T2DM.
• Chronic Disease Cost Calculator (Diabetes) This paper aims at a thorough, detailed, and exhaustive explanation of such a chronic disease as diabetes in terms of the prevalence and cost of treatment in the United States and Maryland.
• Diabetes Mellitus Epidemiology Statistics This study entails a standard established observation order from the established starting time to an endpoint, in this case, the onset of disease, death, or the study’s end. It is crucial to state this value […]
• Epidemiology: Type II Diabetes in Hispanic Americans The prevalence of type II diabetes in Hispanic Americans is well-established, and the search for inexpensive prevention methods is in the limelight.
• Diabetes: Risk Factors and Effects Trends in improved medical care and the development of technology and medicine are certainly contributing to the reduction of the problem. All of the above indicates the seriousness of the problem of diabetes and insufficient […]
• Barriers to Engagement in Collaborative Care Treatment of Uncontrolled Diabetes The primary role of physicians, nurses, and other healthcare team members is to provide patients with medical treatment and coordinate that care while also working to keep costs down and expand access.
• Hereditary Diabetes Prevention With Lifestyle Modification Yeast infections between the fingers and toes, beneath the breast, and in or around the genital organs are the common symptoms of type 2 diabetes.
• Health Equity Regarding Type 2 Diabetes According to Tajkarimi, the number of research reports focusing on T2D’s prevalence and characteristics in underserved minorities in the U. Adapting the program’s toolkits to rural Americans’ eating and self-management habits could also be instrumental […]
• Diabetes Mellitus: Treatment Methods Moreover, according to the multiple findings conducted by Park et al, Billeter et al, and Tsilingiris et al, bariatric surgeries have a positive rate of sending diabetes into remission.
• Diagnosing Patient with Insulin-Dependent Diabetes The possible outcomes of the issues that can be achieved are discussing the violations with the patient’s family and convincing them to follow the medical regulations; convincing the girl’s family to leave her at the […]
• Human Service for Diabetes in Late Adulthood The mission of the Georgia Diabetic Foot Care Program is to make a positive difference in the health of persons living with diabetes.
• Diabetes: Symptoms and Risk Factors In terms of the problem, according to estimates, 415 million individuals worldwide had diabetes mellitus in 2015, and it is expected to rise to 642 million by the year 2040.
• Diabetes: Types and Management Diabetes is one of the most prevalent diseases in the United States caused when the body fails to optimally metabolize food into energy.
• Epidemiology of Diabetes and Forecasted Trends The authors note that urbanization and the rapid development of economies of different countries are the main causes of diabetes. The authors warn that current diabetes strategies are not effective since the rate of the […]
• The Aboriginal Diabetes Initiative in Canada The ADI’s goal in the CDS was to raise type 2 diabetes awareness and lower the incidence of associated consequences among Aboriginal people.
• Communicating the Issue of Diabetes The example with a CGM sensor is meant to show that doctors should focus on educating people with diabetes on how to manage their condition and what to do in extreme situations.
• Obesity and Diabetes Mellitus Type 2 The goal is to define the features of patient information to provide data on the general course of the illness and its manifestations following the criteria of age, sex, BMI, and experimental data.
• The Prevention of Diabetes and Its Consequences on the Population At the same time, these findings can also be included in educational programs for people living with diabetes to warn them of the risks of fractures and prevent them.
• Uncontrolled Type 2 Diabetes and Depression Treatment The data synthesis demonstrates that carefully chosen depression and anxiety treatment is likely to result in better A1C outcomes for the patient on the condition that the treatment is regular and convenient for the patients.
• Type 2 Diabetes: Prevention and Education Schillinger et al.came to the same conclusion; thus, their findings on the study of the Bigger Picture campaign effectiveness among youth of color are necessary to explore diabetes prevention.
• A Diabetes Quantitative Article Analysis The article “Correlates of accelerometer-assessed physical activity and sedentary time among adults with type 2 diabetes” by Mathe et al.refers to the global issue of the prevention of diabetes and its complications.
• A Type 2 Diabetes Quantitative Article Critique Therefore, the main issue is the prevention of type 2 diabetes and its consequences, and this paper will examine one of the scientific studies that will be used for its exploration.
• The Diabetes Prevention Articles by Ford and Mathe The main goal of the researchers was to measure the baseline MVPA of participants and increase their activity to the recommended 150 minutes per week through their participation in the Diabetes Community Lifestyle Improvement Program.
• Type 2 Diabetes in Hispanic Americans The HP2020 objectives and the “who, where, and when” of the problem highlight the significance of developing new, focused, culturally sensitive T2D prevention programs for Hispanic Americans.
• Diabetes Mellitus as Problem in US Healthcare Simultaneously, insurance companies are interested in decreasing the incidence of diabetes to reduce the costs of testing, treatment, and provision of medicines.
• Diabetes Prevention as a Change Project All of these queries are relevant and demonstrate the importance of including people at high risk of acquiring diabetes in the intervention.
• Evidence Synthesis Assignment: Prevention of Diabetes and Its Complications The purpose of this research is to analyze and synthesize evidence of good quality from three quantitative research and three non-research sources to present the problem of diabetes and justify the intervention to address it.
• Diabetes Mellitus: Causes and Health Challenges Second, the nature of this problem is a clear indication of other medical concerns in this country, such as poor health objectives and strategies and absence of resources.
• Diabetes in Adults in Oxfordshire On a national level, Diabetes Research and Wellness Foundation aims to prevent the spread of the decease through research of the causes and effective treatment of diabetes 2 type.
• Diabetes Mellitus (DM) Disorder Case Study Analysis Thus, informing the patient about the importance of regular medication intake, physical activity, and adherence to diet in maintaining diabetes can solve the problem.
• Diabetes Mellitus in Young Adults Thus, programs for young adults should predominantly focus on the features of the transition from adolescence to adulthood. As a consequence, educational programs on diabetes improve the physical and psychological health of young adults.
• A Healthcare Issue of Diabetes Mellitus Diabetes mellitus is seen as a primary healthcare issue that affects populations across the globe and necessitates the combination of a healthy lifestyle and medication to improve the quality of life of people who suffer […]
• Control of LDL Cholesterol Levels in Patients, Gestational Diabetes Mellitus In addition, some patients with hypercholesterolemia may have statin intolerance, which reduces adherence to therapy, limits treatment efficacy, and increases the risk of CVD.
• Exploring Glucose Tolerance and Gestational Diabetes Mellitus In the case of a glucose tolerance test for the purpose of diagnosing GDM type, the interpretation of the test results is carried out according to the norms for the overall population.
• Type 2 Diabetes Health Issue and Exercise This approach will motivate the patient to engage in exercise and achieve better results while reducing the risk of diabetes-related complications.
• Diabetes Interventions in Children The study aims to answer the PICOT Question: In children with obesity, how does the use of m-Health applications for controlling their dieting choices compare to the supervision of their parents affect children’s understanding of […]
• Diabetes Tracker Device and Its Advantages The proposed diabetes tracker is a device that combines the functionality of an electronic BGL tester and a personal assistant to help patients stick to their diet plan.
• Disease Management for Diabetes Mellitus The selection of the appropriate philosophical and theoretical basis for the lesson is essential as it allows for the use of an evidence-based method for learning about a particular disease.
• Latino People and Type 2 Diabetes The primary aim of the study is to determine the facilitators and barriers to investigating the decision-making process in the Latin population and their values associated with type 2 diabetes.
• Diabetes Self-Management Education and Support Program The choice of this topic and question is based on the fact that despite the high prevalence of diabetes among adolescents in the United States, the use of DSMES among DM patients is relatively low, […]
• Diabetes Mellitus Care Coordination The aim is to establish what medical technologies, care coordination and community resources, and standards of nursing practice contribute to the quality of care and safety of patients with diabetes.
• Healthy Lifestyle Interventions in Comorbid Asthma and Diabetes In most research, the weight loss in cases of comorbid asthma and obesity is reached through a combination of dietary interventions and physical exercise programs.
• Diabetes: Statistics, Disparities, Therapies The inability to produce adequate insulin or the body’s resistance to the hormone is the primary cause of diabetes. Diabetes is a serious health condition in the U.S.and the world.
• Type 2 Diabetes Prescriptions and Interventions The disadvantage is the difficulty of obtaining a universal model due to the complexity of many factors that can affect the implementation of recommendations: from the variety of demographic data to the patient’s medical history.
• Health Education for Female African Americans With Diabetes In order to address and inform the public about the challenges, nurses are required to intervene by educating the population on the issues to enhance their understanding of the risks associated with the conditions they […]
• Diabetes Risk Assessment and Prevention It is one of the factors predisposing patients suffering from diabetes to various cardiovascular diseases. With diabetes, it is important to learn how to determine the presence of carbohydrates in foods.
• Diabetes Mellitus: Preventive Measures In addition to addressing the medical specialists who will be of service in disease prevention, it will emphasize the intervention programs required to help control the spread of the illness.
• “The Diabetes Online Community” by Litchman et al. The researchers applied the method of telephone interviews to determine the results and effectiveness of the program. The study described the value of DOC in providing support and knowledge to older diabetes patients.
• Mobile App for Improved Self-Management of Type 2 Diabetes The central focus of the study was to assess the effectiveness of the BlueStar app in controlling glucose levels among the participants.
• Type 2 Diabetes in Minorities from Cultural Perspective The purpose of this paper is to examine the ethical and cultural perspectives on the issue of T2DM in minorities. Level 2: What are the ethical obstacles to treating T2DM in ethnic and cultural minorities?
• Ethics of Type 2 Diabetes Prevalence in Minorities The purpose of this article analysis is to dwell on scholarly evidence that raises the question of ethical and cultural aspects of T2DM prevalence in minorities.
• Type 2 Diabetes in Minorities: Research Questions The Level 2 research questions are: What are the pathophysiological implications of T2DM in minorities? What are the statistical implications of T2DM in minorities?
• Improving Adherence to Diabetes Treatment in Primary Care Settings Additionally, the patients from the intervention group will receive a detailed explanation of the negative consequences of low adherence to diabetes treatment.
• An Advocacy Tool for Diabetes Care in the US To ensure the implementation and consideration of my plea, I sent a copy of the letter to the government officials so it could reach the president.
• Diabetes and Allergies: A Statistical Check The current dataset allowed us to test the OR for the relationship between family history of diabetes and the presence of diabetes in a particular patient: all variables were dichotomous and discrete and could take […]
• Type 2 Diabetes in Adolescents According to a National Diabetes Statistics Report released by the Centers for Disease Control and Prevention, the estimated prevalence of the disease was 25 cases per 10,000 adolescents in 2017. A proper understanding of T2D […]
• Analysis of Diabetes and Its Huge Effects In the US, diabetes is costly to treat and has caused much physical, emotional and mental harm to the people and the families of those who have been affected by the disease.
• Nursing: Self-Management of Type II Diabetes Sandra Fernandes and Shobha Naidu’s journal illustrates the authors’ understanding of a significant topic in the nursing profession.”Promoting Participation in self-care management among patients with diabetes mellitus” article exposes readers to Peplau’s theory to understand […]
• The Impact of Vegan and Vegetarian Diets on Diabetes Vegetarian diets are popular for a variety of reasons; according to the National Health Interview Survey in the United States, about 2% of the population reported following a vegetarian dietary pattern for health reasons in […]
• “Diabetes Prevention in U.S. Hispanic Adults” by McCurley et al. This information allows for supposing that face-to-face interventions can be suitable to my practicum project that considers measures to improve access to care among African Americans with heart failure diseases. Finally, it is possible to […]
• Diabetes Disease of the First and Second Types It is a decrease in the biological response of cells to one or more effects of insulin at its average concentration in the blood. During the first type of diabetes, insulin Degludec is required together […]
• Person-Centered Strategy of Diabetes and Dementia Care The population of focus for this study will be Afro-American women aged between sixty and ninety who have diabetes of the second type and dementia or are likely to develop dementia in the future.
• Video Consultations Between Patients and Clinicians in Diabetes, Cancer, and Heart Failure Services For example, during one of my interactions with the patient, I was asked whether the hospital had the policy to avoid face-to-face interaction during the pandemic with the help of video examinations.
• Diets to Prevent Heart Disease, Cancer, and Diabetes In order to prevent heart disease, cancer, and diabetes, people are required to adhere to strict routines, including in terms of diet. Additionally, people wanting to prevent heart disease, cancer, and diabetes also need to […]
• The Centers for Diabetes’ Risks Assessment In general, the business case for the Centers for Diabetes appears to be positive since the project is closely aligned with the needs of the community and the targets set by the Affordable Care Act.
• Diabetes Management Type 1 and Type 2 diabetes contrast based on their definitions, the causes, and the management of the conditions. Since the CDC promotes the avoidance of saturated fat and the increase of fiber intake for […]
• Intervention Methods for Type 2 Diabetes Mellitus An individual should maintain a regulated glycemic control using the tenets of self-management to reduce the possibility of complications related to diabetes.
• Diabetes Mellitus as Leading Cause of Disability The researchers used data from the Centers for Disease Control and Prevention, where more than 12% of older people in the US live with the condition.
• Depression in Diabetes Patients The presence of depression concomitant to diabetes mellitus prevents the adaptation of the patient and negatively affects the course of the underlying disease.
• The Relationship Between Diabetes and COVID-19 After completing the research and analyzing the articles, it is possible to suggest a best practice that may be helpful and effective in defining the relationship between diabetes and COVID-19 and providing a way to […]
• Pre-diabetes and Urinary Incontinence Most recent reports indicate that a physiotherapy procedure gives a positive result in up to 80% of patients with stage I or SUI and mixed form and 50% of patients with stage II SUI.
• Type 1 Diabetes: Recommendations for Alternative Drug Treatments Then, they have to assess the existing levels of literacy and numeracy a patient has. Tailoring educational initiatives to a person’s unique ethnic and cultural background is the basis of cultural competence in patient education.
• Type 2 Diabetes: A Pharmacologic Update Diabetes presents one of the most common diagnoses in causes of ED visits among adults and one of the leading causes of death in the United States.
• Diabetes: Vulnerability, Resilience, and Care In nursing care, resilience is a critical concept that shows the possibility of a person to continue functioning and meeting objectives despite the existing challenges.
• Diabetes Prevention in the United States The analysis of these policies and the other strategies provides the opportunity to understand what role they might play in the improvement of human health. NDPP policy, on the other hand, emphasizes the role of […]
• Teaching Experience: Diabetes Prevention The primary objective of the seminar is to reduce the annual number of diabetes cases and familiarize the audience with the very first signs of this disease.
• Summary of Type 2 Diabetes: A Pharmacologic Update The authors first emphasize that T2D is one of the most widespread diseases in the United States and the seventh leading cause of death.
• Insulin Effects in a Diabetes Person I will use this source to support my research because the perception of diabetes patients on insulin therapy is essential for understanding the impact they cause on the person.
• Diabetes and Medical Intervention In the research conducted by Moin et al, the authors attempted to define the scope of efficiency of such a tool as an online diabetes prevention program in the prevention of diabetes among obese/overweight population […]
• Relation Between Diabetes And Nutrition Any efforts to lessen and eliminate the risk of developing diabetes must involve the dietary habit of limiting the consumption of carbohydrates, sugar, and fats. According to Belfort-DeAguiar and Dongju, the three factors of obesity, […]
• Diabetes Mellitus Type 2 and a Healthy Lifestyle Relationship The advantage of this study over the first is that the method uses a medical approach to determining the level of fasting glucose, while the dependences in the study of Ugandans were found using a […]
• Diabetes and Its Economic Effect on Healthcare For many years, there has been an active increase in the number of cases of diabetes of all types among the global population, which further aggravates the situation.
• Pathogenesis and Prevention of Diabetes Mellitus and Hypertension The hormone is produced by the cells of the islets of Langerhans found in the pancreas. It is attributed to the variation in the lifestyle of these individuals in these two geographical zones.
• Parental Intervention on Self-Management of an Adolescent With Diabetes Diabetes development and exposure are strongly tied to lifestyle, and the increasing incidents rate emphasizes the severity of the population’s health problem.
• Addressing the Needs of Hispanic Patients With Diabetes Similarly, in the program at hand, the needs of Hispanic patients with diabetes will be considered through the prism of the key specifics of the community, as well as the cultural background of the patients.
• Diabetes Issues: Insulin Price and Unaffordability According to the forecast of researchers from Stanford University, the number of people with type 2 diabetes who need insulin-containing drugs in the world will increase by about 79 million people by 2030, which will […]
• Diabetes: Epidemiologic Study Design For instance, the range of their parents’ involvement in the self-management practices can be a crucial factor in treatment and control.
• What to Know About Diabetes? Type 1 diabetes is caused by autoimmune reaction that prevent realization of insulin in a body. Estimated 5-10% of people who have diabetes have type 1.
• Diabetes in Saudi Arabia It is expected that should this underlying factor be discovered, whether it is cultural, societal, or genetic in nature, this should help policymakers within Saudi Arabia create new governmental initiatives to address the problem of […]
• “Medical Nutrition Therapy: A Key to Diabetes Management and Prevention” Article Analysis In the process of MNT application, the dietitian keeps a record of the changes in the main components of food and other components of the blood such as blood sugars to determine the trend to […]
• Global and Societal Implications of the Diabetes Epidemic The main aim of the authors of this article seems to be alerting the reader on the consequences of diabetes to the society and to the whole world.
• Diabetes and Hypertension Avoiding Recommendations Thus, the promotion of a healthy lifestyle should entail the encouragement of the population to cease smoking and monitor for cholesterol levels.
• Pregnant Women With Type I Diabetes: COVID-19 Disease Management The grounded theory was selected for the given topic, and there are benefits and drawbacks of utilizing it to study the experiences of pregnant women with type I diabetes and COVID-19.
• Current Recommendations for the Glycemic Control in Diabetes Management of blood glucose is one of the critical issues in the care of people with diabetes. Therefore, the interval of the A1C testing should also depend on the condition of the patient, the physician’s […]
• Diabetes Mellitus: Types, Causes, Presentation, Treatment, and Examination Diabetes mellitus is a chronic endocrinologic disease, which is characterized by increased blood glucose concentration.
• Diabetes Problem at Country Walk Community: Intervention and Evaluation This presentation develops a community health nursing intervention and evaluation tool for the diabetes problem affecting Country Walk community.
• The Minority Diabetes Initiative Act’s Analysis The bill provides the right to the Department of Health and Human Services to generate grants to public and nonprofit private health care institutions with the aim of providing treatment for diabetes in minority communities.
• Communication Challenges Between Nurses and Patients With Type 2 Diabetes According to Pung and Goh, one of the limitations of communication in a multicultural environment is the language barrier that manifests itself in the direct interaction of nurses with patients and in the engagement work […]
• Diabetes Type 2 from Management Viewpoint Demonstrate the effects of type 2 diabetes and provide background information on the disease; Discuss the management plans of diabetes centers and critically analyze the frameworks implemented in the hospitals; Examine the existing methodology models […]
• Nursing Plan for the Patient with Diabetes Type 2, HTN, and CAD The health of the population is the most valuable achievement of society, so the preservation and strengthening of it is an essential task in which everyone should participate without exception.
• Diagnosis and Classification of Diabetes Mellitus Diabetes is a serious public health concern that introduces a group of metabolic disorders caused by changes in the sugar blood level.
• Diabetes Mellitus Type II: A Case of a Female Adult Patient In this presentation, we are going to develop a care plan for a 47-year-old woman with a 3-year-old history of Diabetes Mellitus Type 2 (also known as Type II DM).
• Diabetes Insipidus: Disease Process With Implications for Healthcare Professionals This presentation will consider the topic of Diabetes Insipidus (DI) with a focus on its etiology and progress.
• A Study of Juvenile Type 1 Diabetes in the Northwest of England The total number of children under seventeen years living with type 1 diabetes in North West England by 2009 was 2,630.
• Imperial Diabetes Center Field Study The purpose is to examine the leadership’s practices used to maintain and improve the quality and safety standards of the facility and, using the observations and scholarly research, offer recommendations for improvement.
• Diabetes Risk Assessment After completing the questionnaire, I learned that my risk for the development of diabetes is above average. Modern risk assessment tools allow identifying the current state of health and possibilities of developing the disease.
• The Role of Telenursing in the Management of Diabetes Type 1 Telemedicine is the solution that could potentially increase the coverage and improve the situation for many t1DM patients in the world.
• Health Issues of Heart Failure and Pediatric Diabetes As for the population, which is intended to participate in the research, I am convinced that there is the need to specify the patients who should be examined and monitored.
• Juvenile Diabetes: Demographics, Statistics and Risk Factors Juvenile diabetes, also referred to as Type 2 diabetes or insulin-dependent diabetes, describes a health condition associated with the pancreas’s limited insulin production. The condition is characterized by the destruction of the cells that make […]
• Diabetes Mellitus: Pathophysiologic Processes The main function of insulin produced by cells within the pancreas in response to food intake is to lower blood sugar levels by the facilitation of glucose uptake in the cells of the liver, fat, […]
• Type 2 Diabetes Management in Gulf Countries One such study is the systematic review on the quality of type 2 diabetes management in the countries of the cooperation council for the Arab states of the Gulf, prepared by Alhyas, McKay, Balasanthiran, and […]
• Patient with Ataxia and Diabetes Mellitus Therefore, the therapist prioritizes using the cushion to the client and persuades the patient to accept the product by discussing the merits of the infinity cushion with a low profile in enabling the customer to […]
• Diabetes Evidence-Based Project: Disseminating Results In this presentation, the involvement of mentors and collaboration with administration and other stakeholders are the preferred steps, and the idea to use social networking and web pages has to be removed.
• The Problem of Diabetes Among African Americans Taking into consideration the results of the research and the information found in the articles, the problem of diabetes among African Americans has to be identified and discussed at different levels.
• Childhood Obesity, Diabetes and Heart Problems Based on the data given in the introduction it can be seen that childhood obesity is a real problem within the country and as such it is believed that through proper education children will be […]
• Hypertension and Antihypertensive Therapy and Type 2 Diabetes Mellitus In particular, Acebutolol impairs the functions of epinephrine and norepinephrine, which are neurotransmitters that mediate the functioning of the heart and the sympathetic nervous system.
• Diabetes: Diagnosis and Treatment The disease is characterized by the pancreas almost not producing its own insulin, which leads to an increase in glucose levels in the blood.
• How to Manage Type 2 Diabetes The article is significant to the current research problem as the researchers concluded that the assessment of metabolic processes in diabetic patients was imperative for adjusting in the management of the condition.
• Clinical Trial of Diabetes Mellitus On the other hand, type II diabetes mellitus is caused by the failure of the liver and muscle cells to recognize the insulin produced by the pancreatic cells.
• Diabetes: Diagnosis and Related Prevention & Treatment Measures The information presented on the articles offers an insight in the diagnosis of diabetes among various groups of persons and the related preventive and treatment measures. The study identified 3666 cases of initial stages of […]
• Reinforcing Nutrition in Schools to Reduce Diabetes and Childhood Obesity For example, the 2010 report says that the rates of childhood obesity have peaked greatly compared to the previous decades: “Obesity has doubled in Maryland over the past 20 years, and nearly one-third of youth […]
• The Connection Between Diabetes and Consuming Red Meat In light of reporting the findings of this research, the Times Healthland gave a detailed report on the various aspects of this research.
• Synthesizing the Data From Relative Risk Factors of Type 2 Diabetes Speaking of such demographic factors as race, the white population suffers from it in the majority of cases, unlike the rest of the races, the remaining 0.
• Using Exenatide as Treatment of Type 2 Diabetes Mellitus in Adults Kendal et al.analyzed the effects of exenatide as an adjunct to a combination of metformin and sulfonylurea against the combination of the same drugs without the adjunct.
• Enhancing Health Literacy for People With Type 2 Diabetes Two professionals, Andrew Long, a professor in the school of heath care in the University of Leeds, and Tina Gambling, senior lecturer in the school of health care studies from the University of Cardiff, conducted […]
• The Scientific Method of Understanding if Coffee Can Impact Diabetes The hypothesis of the experiment ought to be straightforward and understandable. The control group and the experiment group for the test are then identified.
• Gestational Diabetes Mellitus: Review This is because of the current patterns that show an increase in the prevalence of diabetes in offspring born to mothers with GDM.
• Health Service Management of Diabetes During the task, Fay makes a countless number of short calls and often takes water irrespective of the time of the day or the prevailing weather conditions.
• Necrotizing Fasciitis: Pathophysiology, Role of Diabetes In the event of such an infection, the body becomes desperate to get rid of the intruders. For WBC, zero is given if the count is below 15cells/mm3, one is given if the count lies […]
• The Benefits of Sharing Knowledge About Diabetes With Physicians In this research, 3600 diabetic patients were surveyed from twelve hospitals, but due to exclusion criterion, only 1,200 were considered for this particular research. The system allocated numbers to the participants out of which 100 […]
• Gestational Diabetes Mellitus – NSW, Australia
• Health and Wellness: Stress, Diabetes and Tobacco Related Problems
• 52-Year-Old Female Patient With Type II Diabetes
• Healthy People Project: Personal Review About Diabetes
• Coronary Heart Disease Aggravated by Type 2 Diabetes and Age
• Diabetes as the Scourge of the 21st Century: Locating the Solution
• Psychosocial Implications of Diabetes Management
• Gestational Diabetes in a Pregnant Woman
• Diabetes Mellitus: Prominent Metabolic Disorder
• Holistic Approach to Man’s Health: Diabetes Prevention
• Holistic Image in Prevention of Diabetes
• Educational Strategies for Diabetes to Patients
• Diabetes and Obesity in the United Arab Emirates
• Epidemiological Problem: Diabetes in Illinois
• Diabetes as a Chronic Condition
• Managing Diabetes Through Genetic Engineering
• Diabetes, Functions of Insulin, and Preventive Practices
• Treating of Diabetes in Adults
• Diabetes II: Reduction in the Incidence
• Community Health Advocacy Project: Diabetes Among Hispanics
• Community Health Advocacy Project: Hispanics With Diabetes
• Hispanics Are More Susceptible to Diabetes That Non-Hispanics
• Rates Diabetes Between Hispanics Males and Females
• Diabetes Mellitus and HFSON Conceptual Framework
• Prince Georges County Community Health Concern: Diabetes
• Fats and Proteins in Relation to Type 2 Diabetes
• Alcohol Interaction With Medication: Type 2 Diabetes
• Critical Analysis of Policy for Type 2 Diabetes Mellitus in Australia
• The Treatment and Management of Diabetes
• Obesity and Diabetes: The Enemies Within
• Impact of Diabetes on the United Arab Emirates’ Economy
• Childhood Obesity and Type 2 Diabetes
• Diabetes Management: How Lifestyle, Daily Routine Affect Blood Sugar
• Diabetes Management: Diagnostics and Treatment
• Diabetes Mellitus Type 2: The Family Genetic History
• Diabetes Type II: Hormonal Mechanism and Intracellular Effects of Insulin
• Social, Behavioral, and Psychosocial Causes of Diseases: Type 2 Diabetes
• Supportive Intervention in the Control of Diabetes Mellitus
• Enhancing Foot Care Practices in Patients With Diabetes
• Community Health Promotion: The Fight Against Diabetes in a Community Setting
• Diabetes in Australia and Saudi Arabia
• Diabetes: The Advantages and Disadvantages of Point of Care Testing
• Diabetes Mellitus Type 2 or Non-Insulin-Dependent Diabetes Mellitus
• Qualitative Research in Diabetes Management in Elderly Patient
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Latest Research on Diabetes

Diabetes, a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces, is recognized by the World Health Organization as a major cause of mortality around the world.

At Dove Medical Press, we have curated the most recent diabetes research from our diverse range of journals. Thank you to our community of authors and peer reviewers who persistently contribute to the fight against this disease.

This content is free to access and updated daily.

- 468 records -

Exploring the Biological Effects of Anti-Diabetic Vanadium Compounds in the Liver, Heart and Brain

Dayanand Y, Pather R, Xulu N, Booysen I, Sibiya N, Khathi A, Ngubane P

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:3267-3278

Published Date: 4 September 2024

Causes of Excess Mortality in Diabetes Patients Without Coronary Artery Disease: A Cohort Study Revealing Endocrinologic Contributions

Birindwa G, Maeng M, Thrane PG, Gyldenkerne C, Thomsen RW, Olesen KKW

Clinical Epidemiology 2024 , 16:571-585

Published Date: 3 September 2024

Comparing the Self-Reported Acceptability of Discrete Choice Experiment and Best-Worst Scaling: An Empirical Study in Patients with Type 2 Diabetes Mellitus

Li F, Liu S, Gu Y, Li S, Tao Y, Wei Y, Chen Y

Patient Preference and Adherence 2024 , 18:1803-1813

Published Date: 30 August 2024

Evaluation of Vicarious Somatosensory Experience in Diabetes Mellitus: Bases for Empathy and Social Cognition

Amin SN, El-Akabawy G, Baker Saleh L, Sulaiman AS, Alsharif AA, Ahmed Qamoum M, Basheer Fahmawi M, Al-Matrouk A, Taha H, Ismail AA

Risk Management and Healthcare Policy 2024 , 17:1975-1986

Published Date: 15 August 2024

Correlation Between Growth Differentiation Factor-15 and Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus

Li Y, Wang Y, Cao Y, Zhang X, Dai W, Zhao Y, Zhang L, Han X

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:3019-3028

Published Date: 14 August 2024

Lower Visceral Fat is Related to Diabetic Peripheral Neuropathy

Sun L, Zhang X, Yang J, Yuan J, Lei X

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2967-2974

Published Date: 8 August 2024

Integrated Transcriptomics and Proteomics Identified CMPK1 as a Potential Biomarker for Type 2 Diabetes Mellitus

Zhao K, Mao R, Yi W, Ren Z, Liu Y, Yang H, Wang S, Feng Z

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2923-2934

Published Date: 1 August 2024

Impact of Lipids on Insulin Resistance: Insights from Human and Animal Studies

Elkanawati RY, Sumiwi SA, Levita J

Drug Design, Development and Therapy 2024 , 18:3337-3360

Published Date: 31 July 2024

Patient Characteristics and Outcomes of Hospitalized Chronic Kidney Disease Patients with and without Type 2 Diabetes Mellitus: Observations from the German Claims Data-Based Cohort of the CaReMe-CKD Multinational Study

Leiner J, Pellissier V, König S, Stellmacher L, Hohenstein S, Schanner C, Kwast S, Kuhlen R, Bollmann A

Clinical Epidemiology 2024 , 16:487-500

Published Date: 22 July 2024

Exploring the Interplay of Diabetes, Deaf Patient Reported Outcomes, and Cancer Screening in Deaf and Hard of Hearing Women

Perrodin-Njoku E, Rao SR, Wang RM, Moreland CJ, Kushalnagar P

International Journal of Women's Health 2024 , 16:1235-1248

Published Date: 12 July 2024

Assessment of Cognitive Flexibility in Jordanian Diabetic Patients by Wisconsin Card Sorting and Trail Making Tests: Implications with Demographic, Anthropometric and Therapeutic Variables

Amin SN, El-Akabawy G, Abuqasem MA, AL-Rawashdeh AA, Ayyad MM, Ibrahim AK, AlShawagfeih AM, Ebdah SK, AlHajri RJ, Ismail AA

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2655-2670

Published Date: 1 July 2024

Importance of Assessing Sarcopenia in Patients with Type 2 Diabetes Mellitus Based on Body Fat Percentage Measured by Dual-Energy X-Ray Absorptiometry in Different Genders

Hou B, Wei X, Yang M, Cao Y, Dai W

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2571-2581

Published Date: 25 June 2024

New Diabetic Treatment by Alleviation of Autonomic Nervous System Dysfunction Measured as Periosteal Pressure Sensitivity at Sternum Improves Empowerment, Treatment Satisfaction, and Self-Reported Health of People with Type 2 Diabetes: A Randomized Trial

Hecquet SK, Ballegaard S, Eldrup E, Hansen CS, Hansen TW, Harboe GS, Rossing P, Pichat CSH, Watt T, Gyntelberg F, Ørsted N, Faber JO

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2519-2531

Published Date: 19 June 2024

Efficacy and Safety of DPP-4 Inhibitors and Metformin Combinations in Type 2 Diabetes: A Systematic Literature Review and Network Meta-Analysis

Chen R, Li J, Chen D, Wen W, Zhang S, Li J, Ruan Y, Zhang Z, Sun J, Chen H

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2471-2493

The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets

Reed J, Bain SC, Kanamarlapudi V

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2419-2456

Published Date: 13 June 2024

A Novel Diabetic Arthritic Model in Rats Induced by Streptozotocin, High-Fat Diet, and Complete Freund’s Adjuvant

Boedijono DR, Dilogo IH, Prasetyo M, Antarianto RD, Dewi FNA, Yunir E, Kekalih A, Nugroho A, Aprilya D

Orthopedic Research and Reviews 2024 , 16:163-170

Published Date: 11 June 2024

Integrated Bioinformatics Analysis Revealed Immune Checkpoint Genes Relevant to Type 2 Diabetes

Zhang Z, Sun G, Wang Y, Wang N, Lu Y, Chen Y, Xia F

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2385-2401

Effects of Different Carbohydrate Content Diet on Gut Microbiota and Aortic Calcification in Diabetic Mice

Shen X, Guo G, Feng G, Wang Z

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2327-2346

Published Date: 10 June 2024

Gestational Diabetes Mellitus Risk Factors in Pregnant Women Attending Public Health Institutions in Ethiopia’s Sidama Region: An Unmatched Case-Control Study

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2303-2316

Published Date: 7 June 2024

Evaluation of MASLD Fibrosis, FIB-4 and APRI Score in MASLD Combined with T2DM and MACCEs Receiving SGLT2 Inhibitors Treatment

Liu H, Hao YM, Jiang S, Baihetiyaer M, Li C, Sang GY, Li Z, Du GL

International Journal of General Medicine 2024 , 17:2613-2625

Published Date: 5 June 2024

Plasma Asprosin Concentrations are Associated with Progression of Diabetic Kidney Disease

Xu M, Zhang C, Zhang L, Qu H, Wang Y

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2235-2242

Assessment of Health-Related Quality of Life Among Patients with Chronic Diseases and Its Relationship with Multimorbidity: A Cross-Sectional Study from Saudi Arabia

Alzarea AI, Khan YH, Alzarea SI, Alanazi AS, Alsaidan OA, Alrowily MJ, Al-Shammari M, Almalki ZS, Algarni MA, Mallhi TH

Patient Preference and Adherence 2024 , 18:1077-1094

Published Date: 4 June 2024

Current Perspectives, Practices, and Barriers Faced by Community Pharmacists Regarding Pharmaceutical Care Services for Diabetes Mellitus in the United Arab Emirates

Jairoun AA, Al-Hemyari SS, Shahwan M, Jairoun SA, Alorfi NM, Zyoud SH, Suliman AA, Shahwan MK, Alnuaimi G, Shahwan M, Al-Qirim T, El-Dahiyat F

Journal of Multidisciplinary Healthcare 2024 , 17:2563-2576

Published Date: 23 May 2024

The Prevalence of Sleep Disorders in People with Type 2 Diabetes and Obesity in Saudi Arabia: A Cross-Sectional Study

AL-asiri IS, Almatrafi FG, Al-thagafi SD, AlQarni AM, Aljubran HJ, Aljamaan AK, Al-Zahrani N

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:2075-2083

Published Date: 20 May 2024

Machine Learning-Based Predictive Modeling of Diabetic Nephropathy in Type 2 Diabetes Using Integrated Biomarkers: A Single-Center Retrospective Study

Zhu Y, Zhang Y, Yang M, Tang N, Liu L, Wu J, Yang Y

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1987-1997

Published Date: 10 May 2024

Correlation Between Blood Urea Nitrogen and Short- and Long-Term Glycemic Variability in Elderly Patients with Type 2 Diabetes Mellitus Who Were hospitalized:A Retrospective Study

Huang L, Wang Z, Pan Y, Zhou K, Zhong S

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1973-1986

Published Date: 8 May 2024

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Alswat KA, Almorgi Z, Aljardahi AN, Alobaylan RM, Altowairqi MK, Almorgi MW, Almalki DM, Alshehri KM

Journal of Multidisciplinary Healthcare 2024 , 17:2041-2051

Published Date: 3 May 2024

Causal Association Between Diabetes, Body Mass Index and Lichen Sclerosus: A Bidirectional Two-Sample Mendelian Randomization Analysis

Liu L, Zhang Q, Chang J, Yang K

Clinical, Cosmetic and Investigational Dermatology 2024 , 17:931-940

Published Date: 26 April 2024

Health Technology Assessment: Evaluation of 7 Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus

Xie Z, Hu J, Li M, Hu X, Chen J

Risk Management and Healthcare Policy 2024 , 17:1053-1067

Published Date: 23 April 2024

Correlation Between Serum Vitamin E and HOMA-IR in Patients with T2DM

Zhang J, Hou Y, Zhang Z, Shi Y, Wang Z, Song G

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1833-1843

Prevalence and Associated Factors of Sensorineural Hearing Impairment Among Patients with T2DM in Amhara Region, Northwest Ethiopia, 2022: A Multi-Centered Cross-Sectional Study

Esubalew D, Melese M, Belete M, Ambelu A, Mulat B, Adane T, Wondie WT, Diress M

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1821-1832

Published Date: 20 April 2024

Identification of a Novel Mitochondrial tRNA Mutation in Chinese Family with Type 2 Diabetes Mellitus

Li X, Shang J, Li S, Wang Y

Pharmacogenomics and Personalized Medicine 2024 , 17:149-161

Published Date: 17 April 2024

Serum Folate and Vitamin B12 Modify the Associations of N6AMT1 Genetic Variants with Gestational Diabetes Mellitus: A Cross-Sectional Study in Chinese Pregnant Women

Guo G, Chen X, Zhang J, Meng X, Jia A, Xing X, Huang F, Zhang X, Liu J, Li S, Zhang Q

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1781-1791

Latent Profile Analysis of Medication Beliefs in Patients with Type 2 Diabetes in the Hospital-Home Transition and Comparison with Medication Adherence

Jiang S, Luo T, Zhu Z, Huang Y, Liu H, Li B, Feng S, Zeng K

Patient Preference and Adherence 2024 , 18:839-853

Published Date: 16 April 2024

Fractional Excretion of Urate is Positively Associated with Type 2 Diabetes in HUA Patients: A Cross-Sectional Study

Huang B, Li X, Zhang X, Li S, Liu Y, Zhang M, Cui J

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1701-1713

Published Date: 13 April 2024

A Systematic Guideline by the ASPN Workgroup on the Evidence, Education, and Treatment Algorithm for Painful Diabetic Neuropathy: SWEET

Sayed D, Deer TR, Hagedorn JM, Sayed A, D'Souza RS, Lam CM, Khatri N, Hussaini Z, Pritzlaff SG, Abdullah NM, Tieppo Francio V, Falowski SM, Ibrahim YM, Malinowski MN, Budwany RR, Strand NH, Sochacki KM, Shah A, Dunn TM, Nasseri M, Lee DW, Kapural L, Bedder MD, Petersen EA, Amirdelfan K, Schatman ME, Grider JS

Journal of Pain Research 2024 , 17:1461-1501

Semaglutide Effects on Metabolic Outcomes in Diabetes Mellitus Patients — Real World Study

Balcázar-Valencia CM, García-Ramos AF, Osorio-Toro LM, Ordoñez-Guzmán YA, Buitrago-Gómez N, Cabarcas-López WF, Vizcaino-Guerrero CJ, Daza-Arana JE, Ramírez-Rincón A, Restrepo-Erazo K

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1667-1673

Published Date: 10 April 2024

Diversities of Mechanism in Patients with VHL Syndrome and diabetes: A Report of Two Cases and Literature Review

Wang Y, Liu Z, Zhao W, Cao C, Xiao L, Xiao J

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1611-1619

Published Date: 9 April 2024

Metabolic Syndrome and Tendon Disease: A Comprehensive Review

Lai C, Li R, Tang W, Liu J, Duan XD, Bao D, Liu H, Fu S

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1597-1609

First-Trimester Triglyceride-Glucose Index and Triglyceride/High-Density Lipoprotein Cholesterol are Predictors of Gestational Diabetes Mellitus Among the Four Surrogate Biomarkers of Insulin Resistance

Ma N, Bai L, Lu Q

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1575-1583

Published Date: 8 April 2024

DR10627, a Novel Dual Glucagon‑like Peptide‑1 and Gastric Inhibitory Polypeptide Receptor Agonist for the Treatment of Obesity and Type 2 Diabetes Mellitus

Shao Y, Chen Y, Zhu M, Liu Y, Fang C, Wang M, Sun P, Fu W, Huang J, Sheng S, Huang Y

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1563-1573

Published Date: 6 April 2024

A Nomogram Including Total Cerebral Small Vessel Disease Burden Score for Predicting Mild Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus

Teng Z, Feng J, Xie X, Xu J, Jiang X, Lv P

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1553-1562

Age at Diagnosis of Diabetes in Young Men is Associated with Albuminuria

Zhang Q, Cheng L, Li B, Lu Y, Yang S, Wu Y

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1543-1549

Published Date: 4 April 2024

Cost-Savings Associated with Multi-Disciplinary Team Approach for Reducing Macrovascular and Microvascular Complications in Patients with Type 2 Diabetes: A Predictive Model

Alshowair A, Altamimi S, Alruhaimi FA, Alshahrani S, Alsuwailem F, Alkhaldi M, Abdalla H, Alkhuraiji FH, Alaqeel MS, Almureef SS, Alhawasy S, Abdel-Azeem A

ClinicoEconomics and Outcomes Research 2024 , 16:211-223

Butyrate and Propionate are Negatively Correlated with Obesity and Glucose Levels in Patients with Type 2 Diabetes and Obesity

Zhang S, Zhang Y, Li J, Wang X, Zhang M, Du M, Jiang W, Li C

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1533-1541

Published Date: 2 April 2024

Trajectories of Body Mass Index and Risk for Diabetes Complications and All-Cause Mortality in Finnish Type 2 Diabetes Patients

Wang Z, Lavikainen P, Wikström K, Laatikainen T

Clinical Epidemiology 2024 , 16:203-212

Published Date: 29 March 2024

Type 2 Diabetes, the Epidemic: Trends in Prevalence and Incidence, 2004-2020

Overbeek JA, Nijpels G, Swart KMA, Blom MT, Elders PJM, Herings RMC

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1503-1509

Published Date: 28 March 2024

Study on the Interaction Between C3 Gene Polymorphism and Environment in Patients with Type 2 Diabetes Combined with Coronary Artery Disease

Qiu H, Abudureyimu S, Liu M, Liu F, Gao Y

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1467-1479

Published Date: 27 March 2024

Correlation Between Thyroid-Related Hormones and Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients with Normal Thyroid Function: A Retrospective Study

Xiao M, Luo G, Zhang Z, Liu Y, Gong R, Ke J

Diabetes, Metabolic Syndrome and Obesity 2024 , 17:1481-1490

Published Date: 26 March 2024

Impact of Platelet Hyperreactivity and Diabetes Mellitus on Ischemic Stroke Recurrence: A Single-Center Cohort Clinical Study

Mao Y, Zhu B, Wen H, Zhong T, Bian M

International Journal of General Medicine 2024 , 17:1127-1138

Published Date: 23 March 2024

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Recent Advances

ADA-funded researchers use the money from their awards to conduct critical diabetes research. In time, they publish their findings in order to inform fellow scientists of their results, which ensures that others will build upon their work. Ultimately, this cycle drives advances to prevent diabetes and to help people burdened by it. In 2018 alone, ADA-funded scientists published over 200 articles related to their awards!

Identification of a new player in type 1 diabetes risk

Type 1 diabetes is caused by an autoimmune attack of insulin-producing beta-cells. While genetics and the environment are known to play important roles, the underlying factors explaining why the immune system mistakenly recognize beta-cells as foreign is not known. Now, Dr. Delong has discovered a potential explanation. He found that proteins called Hybrid Insulin Peptides (HIPs) are found on beta-cells of people with type 1 diabetes and are recognized as foreign by their immune cells. Even after diabetes onset, immune cells are still present in the blood that attack these HIPs.

Next, Dr. Delong wants to determine if HIPs can serve as a biomarker or possibly even targeted to prevent or treat type 1 diabetes. Baker, R. L., Rihanek, M., Hohenstein, A. C., Nakayama, M., Michels, A., Gottlieb, P. A., Haskins, K., & Delong, T. (2019). Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes. Diabetes , 68 (9), 1830–1840.

Understanding the biology of body-weight regulation in children

Determining the biological mechanisms regulating body-weight is important for preventing type 2 diabetes. The rise in childhood obesity has made this even more urgent. Behavioral studies have demonstrated that responses to food consumption are altered in children with obesity, but the underlying biological mechanisms are unknown. This year, Dr. Schur tested changes in brain and hormonal responses to a meal in normal-weight and obese children. Results from her study show that hormonal responses in obese children are normal following a meal, but responses within the brain are reduced. The lack of response within the brain may predispose them to overconsumption of food or difficulty with weight-loss.

With this information at hand, Dr. Schur wants to investigate how this information can be used to treat obesity in children and reduce diabetes.

Roth, C. L., Melhorn, S. J., Elfers, C. T., Scholz, K., De Leon, M. R. B., Rowland, M., Kearns, S., Aylward, E., Grabowski, T. J., Saelens, B. E., & Schur, E. A. (2019). Central Nervous System and Peripheral Hormone Responses to a Meal in Children. The Journal of Clinical Endocrinology and Metabolism , 104 (5), 1471–1483.

A novel molecule to improve continuous glucose monitoring

To create a fully automated artificial pancreas, it is critical to be able to quantify blood glucose in an accurate and stable manner. Current ways of continuously monitoring glucose are dependent on the activity of an enzyme which can change over time, meaning the potential for inaccurate readings and need for frequent replacement or calibration. Dr. Wang has developed a novel molecule that uses a different, non-enzymatic approach to continuously monitor glucose levels in the blood. This new molecule is stable over long periods of time and can be easily integrated into miniaturized systems.

Now, Dr. Wang is in the process of patenting his invention and intends to continue research on this new molecule so that it can eventually benefit people living with diabetes.

Wang, B. , Chou, K.-H., Queenan, B. N., Pennathur, S., & Bazan, G. C. (2019). Molecular Design of a New Diboronic Acid for the Electrohydrodynamic Monitoring of Glucose. Angewandte Chemie (International Ed. in English) , 58 (31), 10612–10615.

Addressing the legacy effect of diabetes

Several large clinical trials have demonstrated the importance of tight glucose control for reducing diabetes complications. However, few studies to date have tested this in the real-world, outside of a controlled clinical setting. In a study published this year, Dr. Laiteerapong found that indeed in a real-world setting, people with lower hemoglobin A1C levels after diagnosis had significantly lower vascular complications later on, a phenomenon known as the ‘legacy effect’ of glucose control. Her research noted the importance of early intervention for the best outcomes, as those with the low A1C levels just one-year after diagnosis had significantly lower vascular disease risk compared to people with higher A1C levels.

With these findings in hand, physicians and policymakers will have more material to debate and determine the best course of action for improving outcomes in people newly diagnosed with diabetes.

Laiteerapong, N. , Ham, S. A., Gao, Y., Moffet, H. H., Liu, J. Y., Huang, E. S., & Karter, A. J. (2019). The Legacy Effect in Type 2 Diabetes: Impact of Early Glycemic Control on Future Complications (The Diabetes & Aging Study). Diabetes Care , 42 (3), 416–426.

A new way to prevent immune cells from attacking insulin-producing beta-cells

Replacing insulin-producing beta-cells that have been lost in people with type 1 diabetes is a promising strategy to restore control of glucose levels. However, because the autoimmune disease is a continuous process, replacing beta-cells results in another immune attack if immunosorbent drugs are not used, which carry significant side-effects. This year, Dr. Song reported on the potential of an immunotherapy he developed that prevents immune cells from attacking beta-cells and reduces inflammatory processes. This immunotherapy offers several potential benefits, including eliminating the need for immunosuppression, long-lasting effects, and the ability to customize the treatment to each patient.

The ability to suppress autoimmunity has implications for both prevention of type 1 diabetes and improving success rates of islet transplantation.

Haque, M., Lei, F., Xiong, X., Das, J. K., Ren, X., Fang, D., Salek-Ardakani, S., Yang, J.-M., & Song, J . (2019). Stem cell-derived tissue-associated regulatory T cells suppress the activity of pathogenic cells in autoimmune diabetes. JCI Insight , 4 (7).

A new target to improve insulin sensitivity

The hormone insulin normally acts like a ‘key’, traveling through the blood and opening the cellular ‘lock’ to enable the entry of glucose into muscle and fat cells. However, in people with type 2 diabetes, the lock on the cellular door has, in effect, been changed, meaning insulin isn’t as effective. This phenomenon is called insulin resistance. Scientists have long sought to understand what causes insulin resistance and develop therapies to enable insulin to work correctly again. This year, Dr. Summers determined an essential role for a molecule called ceramides as a driver of insulin resistance in mice. He also presented a new therapeutic strategy for lowering ceramides and reversing insulin resistance. His findings were published in one of the most prestigious scientific journals, Science .

Soon, Dr. Summers and his team will attempt to validate these findings in humans, with the ultimate goal of developing a new medication to help improve outcomes in people with diabetes.

Chaurasia, B., Tippetts, T. S., Mayoral Monibas, R., Liu, J., Li, Y., Wang, L., Wilkerson, J. L., Sweeney, C. R., Pereira, R. F., Sumida, D. H., Maschek, J. A., Cox, J. E., Kaddai, V., Lancaster, G. I., Siddique, M. M., Poss, A., Pearson, M., Satapati, S., Zhou, H., … Summers, S. A. (2019). Targeting a ceramide double bond improves insulin resistance and hepatic steatosis. Science (New York, N.Y.) , 365 (6451), 386–392.

Determining the role of BPA in type 2 diabetes risk

Many synthetic chemicals have infiltrated our food system during the period in which rates of diabetes has surged. Data has suggested that one particular synthetic chemical, bisphenol A (BPA), may be associated with increased risk for developing type 2 diabetes. However, no study to date has determined whether consumption of BPA alters the progression to type 2 diabetes in humans. Results reported this year by Dr. Hagobian demonstrated that indeed when BPA is administered to humans in a controlled manner, there is an immediate, direct effect on glucose and insulin levels.

Now, Dr. Hagobian wants to conduct a larger clinical trial including exposure to BPA over a longer period of time to determine precisely how BPA influences glucose and insulin. Such results are important to ensure the removal of chemicals contributing to chronic diseases, including diabetes.

Hagobian, T. A. , Bird, A., Stanelle, S., Williams, D., Schaffner, A., & Phelan, S. (2019). Pilot Study on the Effect of Orally Administered Bisphenol A on Glucose and Insulin Response in Nonobese Adults. Journal of the Endocrine Society , 3 (3), 643–654.

Investigating the loss of postmenopausal protection from cardiovascular disease in women with type 1 diabetes

On average, women have a lower risk of developing heart disease compared to men. However, research has shown that this protection is lost in women with type 1 diabetes. The process of menopause increases rates of heart disease in women, but it is not known how menopause affects women with type 1 diabetes in regard to risk for developing heart disease. In a study published this year, Dr. Snell-Bergeon found that menopause increased risk markers for heart disease in women with type 1 diabetes more than women without diabetes.

Research has led to improved treatments and significant gains in life expectancy for people with diabetes and, as a result, many more women are reaching the age of menopause. Future research is needed to address prevention and treatment options.

Keshawarz, A., Pyle, L., Alman, A., Sassano, C., Westfeldt, E., Sippl, R., & Snell-Bergeon, J. (2019). Type 1 Diabetes Accelerates Progression of Coronary Artery Calcium Over the Menopausal Transition: The CACTI Study. Diabetes Care , 42 (12), 2315–2321.

Identification of a potential therapy for diabetic neuropathy related to type 1 and type 2 diabetes

Diabetic neuropathy is a type of nerve damage that is one of the most common complications affecting people with diabetes. For some, neuropathy can be mild, but for others, it can be painful and debilitating. Additionally, neuropathy can affect the spinal cord and the brain. Effective clinical treatments for neuropathy are currently lacking. Recently, Dr. Calcutt reported results of a new potential therapy that could bring hope to the millions of people living with diabetic neuropathy. His study found that a molecule currently in clinical trials for the treatment of depression may be valuable for diabetic neuropathy, particularly the type affecting the brain.

Because the molecule is already in clinical trials, there is the potential that it can benefit patients sooner than later.

Jolivalt, C. G., Marquez, A., Quach, D., Navarro Diaz, M. C., Anaya, C., Kifle, B., Muttalib, N., Sanchez, G., Guernsey, L., Hefferan, M., Smith, D. R., Fernyhough, P., Johe, K., & Calcutt, N. A. (2019). Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189. Diabetes , 68 (11), 2143–2154.

ADA-funded researcher studying link between ageing and type 2 diabetes

One of the most important risk factors for developing type 2 diabetes is age. As a person gets older, their risk for developing type 2 diabetes increases. Scientists want to better understand the relationship between ageing and diabetes in order to determine out how to best prevent and treat type 2 diabetes. ADA-funded researcher Rafael Arrojo e Drigo, PhD, from the Salk Institute for Biological Studies, is one of those scientists working hard to solve this puzzle.

Recently, Dr. Arrojo e Drigo published results from his research in the journal Cell Metabolism . The goal of this specific study was to use high-powered microscopes and novel cellular imaging tools to determine the ‘age’ of different cells that reside in organs that control glucose levels, including the brain, liver and pancreas. He found that, in mice, the cells that make insulin in the pancreas – called beta-cells – were a mosaic of both old and young cells. Some beta-cells appeared to be as old as the animal itself, and some were determined to be much younger, indicating they recently underwent cell division.

Insufficient insulin production by beta-cells is known to be a cause of type 2 diabetes. One reason for this is thought to be fewer numbers of functional beta-cells. Dr. Arrojo e Drigo believes that people with or at risk for diabetes may have fewer ‘young’ beta-cells, which are likely to function better than old ones. Alternatively, if we can figure out how to induce the production of younger, high-functioning beta-cells in the pancreas, it could be a potential treatment for people with diabetes.

In the near future, Dr. Arrojo e Drigo’s wants to figure out how to apply this research to humans. “The next step is to look for molecular or morphological features that would allow us to distinguish a young cell from and old cell,” Dr. Arrojo e Drigo said.

The results from this research are expected to provide a unique insight into the life-cycle of beta-cells and pave the way to novel therapeutic avenues for type 2 diabetes.

Watch a video of Dr. Arrojo e Drigo explaining his research!

Arrojo E Drigo, R. , Lev-Ram, V., Tyagi, S., Ramachandra, R., Deerinck, T., Bushong, E., … Hetzer, M. W. (2019). Age Mosaicism across Multiple Scales in Adult Tissues. Cell Metabolism , 30 (2), 343-351.e3.

Researcher identifies potential underlying cause of type 1 diabetes

Type 1 diabetes occurs when the immune system mistakenly recognizes insulin-producing beta-cells as foreign and attacks them. The result is insulin deficiency due to the destruction of the beta-cells. Thankfully, this previously life-threatening condition can be managed through glucose monitoring and insulin administration. Still, therapies designed to address the underlying immunological cause of type 1 diabetes remain unavailable.

Conventional approaches have focused on suppressing the immune system, which has serious side effects and has been mostly unsuccessful. The American Diabetes Association recently awarded a grant to Dr. Kenneth Brayman, who proposed to take a different approach. What if instead of suppressing the whole immune system, we boost regulatory aspects that already exist in the system, thereby reigning in inappropriate immune cell activation and preventing beta-cell destruction? His idea focused on a molecule called immunoglobulin M (IgM), which is responsible for limiting inflammation and regulating immune cell development.

In a paper published in the journal Diabetes , Dr. Brayman and a team of researchers reported exciting findings related to this approach. They found that supplementing IgM obtained from healthy mice into mice with type 1 diabetes selectively reduced the amount of autoreactive immune cells known to target beta-cells for destruction. Amazingly, this resulted in reversal of new-onset diabetes. Importantly, the authors of the study determined this therapy is translatable to humans. IgM isolated from healthy human donors also prevented the development of type 1 diabetes in a humanized mouse model of type 1 diabetes.

The scientists tweaked the original experiment by isolating IgM from mice prone to developing type 1 diabetes, but before it actually occurred. When mice with newly onset diabetes were supplemented with this IgM, their diabetes was not reversed. This finding suggests that in type 1 diabetes, IgM loses its capacity to serve as a regulator of immune cells, which may be contribute to the underlying cause of the disease.

Future studies will determine exactly how IgM changes its regulatory properties to enable diabetes development. Identification of the most biologically optimal IgM will facilitate transition to clinical applications of IgM as a potential therapeutic for people with type 1 diabetes.    Wilson, C. S., Chhabra, P., Marshall, A. F., Morr, C. V., Stocks, B. T., Hoopes, E. M., Bonami, R.H., Poffenberger, G., Brayman, K.L. , Moore, D. J. (2018). Healthy Donor Polyclonal IgM’s Diminish B Lymphocyte Autoreactivity, Enhance Treg Generation, and Reverse T1D in NOD Mice. Diabetes .

ADA-funded researcher designs community program to help all people tackle diabetes

Diabetes self-management and support programs are important adjuncts to traditional physician directed treatment. These community-based programs aim to give people with diabetes the knowledge and skills necessary to effectively self-manage their condition. While several clinical trials have demonstrated the value of diabetes self-management programs in terms of improving glucose control and reducing health-care costs, whether this also occurs in implemented programs outside a controlled setting is unclear, particularly in socially and economically disadvantaged groups.

Lack of infrastructure and manpower are often cited as barriers to implementation of these programs in socioeconomically disadvantaged communities. ADA-funded researcher Dr. Briana Mezuk addressed this challenge in a study recently published in The Diabetes Educator . Dr. Mezuk partnered with the YMCA to evaluate the impact of the Diabetes Control Program in Richmond, Virginia. This community-academic partnership enabled both implementation and evaluation of the Diabetes Control Program in socially disadvantaged communities, who are at higher risk for developing diabetes and the complications that accompany it.

Dr. Mezuk had two primary research questions: (1) What is the geographic and demographic reach of the program? and (2) Is the program effective at improving diabetes management and health outcomes in participants? Over a 12-week study period, Dr. Mezuk found that there was broad geographic and demographic participation in the program. The program had participants from urban, suburban and rural areas, most of which came from lower-income zip codes. HbA1C, mental health and self-management behaviors all improved in people taking part in the Greater Richmond Diabetes Control Program. Results from this study demonstrate the value of diabetes self-management programs and their potential to broadly improve health outcomes in socioeconomically diverse communities. Potential exists for community-based programs to address the widespread issue of outcome disparities related to diabetes.  Mezuk, B. , Thornton, W., Sealy-Jefferson, S., Montgomery, J., Smith, J., Lexima, E., … Concha, J. B. (2018). Successfully Managing Diabetes in a Community Setting: Evidence from the YMCA of Greater Richmond Diabetes Control Program. The Diabetes Educator , 44 (4), 383–394.

Using incentives to stimulate behavior changes in youth at risk for developing diabetes

Once referred to as ‘adult-onset diabetes’, incidence of type 2 diabetes is now rapidly increasing in America’s youth. Unfortunately, children often do not have the ability to understand how everyday choices impact their health. Could there be a way to change a child’s eating behaviors? Davene Wright, PhD, of Seattle Children’s Hospital was granted an Innovative Clinical or Translational Science award to determine whether using incentives, directed by parents, can improve behaviors related to diabetes risk. A study published this year in Preventive Medicine Reports outlined what incentives were most desirable and feasible to implement. A key finding was that incentives should be tied to behavior changes and not to changes in body-weight.

With this information in hand, Dr. Wright now wants to see if incentives do indeed change a child’s eating habits and risk for developing type 2 diabetes. She is also planning to test whether an incentive program can improve behavior related to diabetes management in youth with type 1 diabetes. Jacob-Files, E., Powell, J., & Wright, D. R. (2018). Exploring parent attitudes around using incentives to promote engagement in family-based weight management programs. Preventive Medicine Reports , 10 , 278–284.

Determining the genetic risk for gestational diabetes

Research has identified more than 100 genetic variants linked to risk for developing type 2 diabetes in humans. However, the extent to which these same genetic variants might affect a woman’s probability for getting gestational diabetes has not been investigated.

Pathway to Stop Diabetes ® Accelerator awardee Marie-France Hivert, MD, of Harvard University set out to answer this critical question. Dr. Hivert found that indeed genetic determinants of type 2 diabetes outside of pregnancy are also strong risk factors for gestational diabetes. This study was published in the journal Diabetes .

The implications? Because of this finding, doctors in the clinic may soon be able to identify women at risk for getting gestational diabetes and take proactive steps to prevent it. Powe, C. E., Nodzenski, M., Talbot, O., Allard, C., Briggs, C., Leya, M. V., … Hivert, M.-F. (2018). Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus. Diabetes , 67 (12), 2703–2709.

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How People with Type 2 Diabetes Can Live Longer

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Cost of Diabetes Complications for Medicare Beneficiaries

Diabetes in Young People Is on the Rise

Additional 12 Million US Adults Eligible for Diabetes Screening

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• Review Article
• Published: 11 September 2023

Physiology and Biochemistry

Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions

• Mohammad Azam Ansari   ORCID: orcid.org/0000-0002-6122-5479 1 ,
• Waseem Chauhan 2 ,
• Shoaib Shoaib 3 ,
• Sami A. Alyahya 4 ,
• Mubashshir Ali 5 ,
• Hamid Ashraf 6 ,
• Mohammad N. Alomary 7 &
• Ebtesam A. Al-Suhaimi 8  

International Journal of Obesity volume  47 ,  pages 1179–1199 ( 2023 ) Cite this article

2490 Accesses

9 Citations

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• Gastrointestinal hormones

Diabetes is a serious health issue that causes a progressive dysregulation of carbohydrate metabolism due to insufficient insulin hormone, leading to consistently high blood glucose levels. According to the epidemiological data, the prevalence of diabetes has been increasing globally, affecting millions of individuals. It is a long-term condition that increases the risk of various diseases caused by damage to small and large blood vessels. There are two main subtypes of diabetes: type 1 and type 2, with type 2 being the most prevalent. Genetic and molecular studies have identified several genetic variants and metabolic pathways that contribute to the development and progression of diabetes. Current treatments include gene therapy, stem cell therapy, statin therapy, and other drugs. Moreover, recent advancements in therapeutics have also focused on developing novel drugs targeting these pathways, including incretin mimetics, SGLT2 inhibitors, and GLP-1 receptor agonists, which have shown promising results in improving glycemic control and reducing the risk of complications. However, these treatments are often expensive, inaccessible to patients in underdeveloped countries, and can have severe side effects. Peptides, such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), are being explored as a potential therapy for diabetes. These peptides are postprandial glucose-dependent pancreatic beta-cell insulin secretagogues and have received much attention as a possible treatment option. Despite these advances, diabetes remains a major health challenge, and further research is needed to develop effective treatments and prevent its complications. This review covers various aspects of diabetes, including epidemiology, genetic and molecular basis, and recent advancements in therapeutics including herbal and synthetic peptides.

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Targeting the incretin system in obesity and type 2 diabetes mellitus

Novel therapies with precision mechanisms for type 2 diabetes mellitus

Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1

Data availability.

The datasets utilized and/or analyzed during this study are included in the manuscript.

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Acknowledgements

WC and SS are thankful to Indian Council of Medical Research (ICMR), New Delhi and Council of Scientific and Industrial Research (CSIR), New Delhi for providing senior research fellowship, respectively.

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Wellness and Preventive Medicine Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh, 11442, Saudi Arabia

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Ansari, M.A., Chauhan, W., Shoaib, S. et al. Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions. Int J Obes 47 , 1179–1199 (2023). https://doi.org/10.1038/s41366-023-01369-3

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The top 10 research priorities in diabetes and pregnancy according to women, support networks and healthcare professionals

Göher ayman.

1 National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford UK

James A. Strachan

2 Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Oxford UK

Niamh McLennan

3 MRC Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh UK

Reem Malouf

Jack lowe‐zinola.

4 The Royal Wolverhampton Hospital NHS Trust, New Cross Hospital, Wolverhampton UK

Nia Roberts

5 Bodleian Health Care Libraries, University of Oxford, Oxford UK

Fiona Alderdice

6 School of Nursing and Midwifery, Queen’s University Belfast, Belfast UK

Iuliana Berneantu

Niki breslin, caroline byrne.

7 Cambridge University Hospitals NHS Foundation Trust, Cambridge UK

Sonya Carnell

David churchill.

8 University of Wolverhampton, Wolverhampton UK

Jeannie Grisoni

Jane e. hirst.

9 Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford UK

10 John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford UK

Anna Morris

11 Diabetes UK, Wells Lawrence House, London UK

Helen R. Murphy

12 Norwich Medical School, University of East Anglia, Norwich UK

13 Division of Women's Health, St Thomas’ Campus, King's College London, London UK

14 Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital, Norwich UK

Jane O’Brien

15 Stockport NHS Foundation Trust, Stepping Hill Hospital, Stockport UK

Caroline Schmutz

16 JDRF the Type 1 Diabetes Charity, London UK

Kamini Shah

Ankita s. singal, mark w. j. strachan.

17 Metabolic Unit, Western General Hospital, Edinburgh UK

Katherine Cowan

18 James Lind Alliance, National Institute for Health Research Evaluation, Trials and Studies Coordinating Centre, University of Southampton, Southampton UK

Marian Knight

Associated data.

The top 10 and the full long‐list of indicative questions will be made available on the NPEU project website www.npeu.ox.ac.uk/jla‐psp and JLA website www.jla.nihr.ac.uk/priority‐setting‐partnerships/diabetes‐and‐pregnancy . For further information, please contact the team at ku.ca.xo.uepn@PSPALJ .

To undertake a Priority Setting Partnership (PSP) to establish priorities for future research in diabetes and pregnancy, according to women with experience of pregnancy, and planning pregnancy, with any type of diabetes, their support networks and healthcare professionals.

The PSP used established James Lind Alliance (JLA) methodology working with women and their support networks and healthcare professionals UK‐wide. Unanswered questions about the time before, during or after pregnancy with any type of diabetes were identified using an online survey and broad‐level literature search. A second survey identified a shortlist of questions for final prioritisation at an online consensus development workshop.

There were 466 responses (32% healthcare professionals) to the initial survey, with 1161 questions, which were aggregated into 60 unanswered questions. There were 614 responses (20% healthcare professionals) to the second survey and 18 questions shortlisted for ranking at the workshop. The top 10 questions were: diabetes technology, the best test for diabetes during pregnancy, diet and lifestyle interventions for diabetes management during pregnancy, emotional and well‐being needs of women with diabetes pre‐ to post‐pregnancy, safe full‐term birth, post‐natal care and support needs of women, diagnosis and management late in pregnancy, prevention of other types of diabetes in women with gestational diabetes, women's labour and birth experiences and choices and improving planning pregnancy.

Conclusions

These research priorities provide guidance for research funders and researchers to target research in diabetes and pregnancy that will achieve greatest value and impact.

Novelty statement

• Women report a lack of consistent evidence‐based information to help them manage their diabetes in the period before to after pregnancy.
• The top 10 questions for research in diabetes and pregnancy according to women, their support networks and healthcare professionals were identified.
• Joint top priorities for research were diabetes technology and identifying the best test for diabetes in pregnancy.
• These questions will inform funders of research and researchers towards addressing areas of great need and impact.

1. INTRODUCTION

Approximately one in every 10 women will experience a pregnancy complicated by either pre‐existing or gestational diabetes. 1 Rates are increasing as a result of increased rates of obesity and pregnancy at a later age. 2 Although most women have healthy pregnancies and healthy babies, diabetes increases the risk of complications during pregnancy and birth, and can have long‐term effects. Compared to the maternity population without diabetes, the risks are two to six times greater for adverse outcomes such as congenital anomalies, stillbirth, preterm birth, infant death within the first month of life, together with long‐term risks of adverse cardiovascular outcomes in both mothers and children. 3 , 4

Many pregnant women with diabetes report a lack or inconsistency of information, leaving many of their questions unanswered. National guidelines and high‐quality systematic reviews highlight variable quality, heterogeneity and reliability of research. Consequently, treatment guidelines are insufficiently evidenced in line with current context and available healthcare options. 5 , 6 However, with limited funding and resources available for research, it is important to ensure that the research that is undertaken is of highest value and impact.

Healthcare research led by industry and researchers often does not address the issues that are most important for people living with the condition, or those who support them. 7 The James Lind Alliance (JLA), a UK‐based initiative established in 2004, aims to address this mismatch. Through Priority Setting Partnerships (PSP), the JLA supports the identification of the research questions that matter most to patients and the healthcare professionals that care for them. Sharing the outputs of PSPs with health research funders helps to align the work they fund towards addressing the areas of need prioritised by those directly affected and involved.

Previous successful PSPs have been conducted in diabetes in the UK. The type 1 diabetes PSP identified two questions in pregnancy, but both fell outside the top 10 priorities: ‘What impact do changing hormones, for example, during menstruation, pregnancy and menopause, have on blood glucose levels in women with type 1 diabetes?’; ‘Is it safe to continue insulin analogues in preconception and pregnancy in type 1 diabetes? ’ 8 No priorities specific to pregnancy were identified in the type 2 diabetes PSP top 10. 9 There have also been prioritisation exercises using different but overlapping methodology to PSPs in Canada and ​the USA but focussing on gestational diabetes. 10 , 11 However, women's health and pregnancy, particularly in relation to diabetes, are not prioritised, despite being consistently identified as an area of much needed research. 2 , 12 , 13

A PSP was therefore established between the University of Oxford, Diabetes UK, Diabetes Research and Wellness Foundation, JDRF the type 1 diabetes charity, and JLA, on World Diabetes Day 2018. The PSP aimed to find out the priorities for future research in diabetes and pregnancy, according to women and their support networks (families, partners, friends and carers) with experience of pregnancy, or planning pregnancy, with any type of diabetes and healthcare professionals.

2. PARTICIPANTS AND METHODS

The PSP employed the established JLA methodology. 14

2.1. Establishing the PSP

The PSP was overseen by a steering group representing key stakeholders (Supplementary Table  S1 ) and was chaired by a senior JLA advisor to ensure transparency of the process, and fair and equal involvement of all members. The group agreed the scope (Table  1 ) and was responsible for the completeness and appropriateness of the process, ensuring involvement of key stakeholder groups, approval of categorisation, grouping and phrasing of questions and interpretation of data. The protocol was prospectively published online at www.jla.nihr.ac.uk/priority‐setting‐partnerships/diabetes‐and‐pregnancy .

Scope of the James Lind Alliance priority setting partnership in diabetes and pregnancy

2.2. Initial survey—identifying questions

Women and their support networks (partners, families, friends and carers) with experience of pregnancy or planning pregnancy with any type of diabetes and healthcare professionals were invited via an open survey (26 June–15 November 2019) to suggest up to three questions they felt were important to answer. These could be any questions about the time before, during or after pregnancy with any type of diabetes. The scope was intentionally broad so that the submissions reflected public need.

The survey was available, in English, online and on paper. Targeted efforts to maximise responses, particularly from underrepresented groups, included direct approaches in diabetes and pregnancy clinics, outreach through relevant support groups, professional networks and conferences, diabetes, pregnancy and birth charities’ websites and communication channels and social media platforms. Concerted efforts were made to hear the voices of ethnic minorities working with organisations, support groups and community champions, which aim to address health inequalities. Representation across different ethnic minorities was monitored through broad groupings.

2.3. Categorisation and grouping

The submitted questions were organised using NVivo qualitative data analysis software (QSR International Pty Ltd. Version 12, 2018). Initial data cleaning was manually completed with any issues about the clinical aspects or interpretation of the submitted questions resolved with the steering group. The questions were analysed using content analysis with an initial stage of open coding of the question content, followed by the grouping of codes into categories. 15 To retain the integrity of the initial submissions, some questions were mapped to two or more categories. Independent second checks were conducted with members of the steering group to ensure potential impact of individual bias, and missed or misinterpreted categorisation was minimised. The steering group further consolidated the categories into groups and summarised the initial survey submissions under an indicative question. Indicative questions were formulated to capture the issues raised by the submitted questions within each group, whether originating from single or multiple respondents.

2.4. Evidence checking

A broad level and pragmatic evidence checking strategy was taken (January – May 2020) with the aim of ascertaining whether there was evidence of substantial uncertainty for each indicative question. The search was restricted to the Cochrane Database of Systematic Reviews ( www.cochranelibrary.com ) , systematic reviews published since 2017 using Medline or PubMed and National Institute of Clinical Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN) national diabetes and pregnancy guidelines. 5 , 6 Expanded evidence searches, including evidence highlighted by the steering group, were applied on a question‐by‐question basis after finalisation of the list of indicative questions. Research underway or recently completed but not available as published was not included as evidence. Where part of the question had sufficient evidence, the question phrasing was amended to reflect the remaining uncertainty.

2.5. Interim survey and prioritisation

The interim survey presented the long list of indicative questions in groups by phase. The order of the groups and individual questions within the groups were randomised each time the survey was entered. Participants were invited to pick up to 10 that they felt were most important to answer. Due to the Covid‐19 pandemic and social distancing restrictions, the survey was offered online only. Following a pilot mid‐May, the survey ran for nine weeks (29 May–31 July 2020).

2.6. Interim ranking and shortlisting

Every selection made by an individual respondent had equal weighting and no weighting changes were made if fewer than 10 questions were selected. However, to account for the differences in observed voting patterns and the number of respondents from different groups, ranking was tallied separately for: women and support networks, healthcare professionals, ethnic minorities and diabetes type, namely type 1, type 2 and other, and gestational diabetes. Within each of the groups, the total points for each question were put into rank order. The questions ranked in the top 10 for the two main groups (women/support networks and healthcare professionals), and the top three, and at least eight of the top 10, for each of the other subgroups, were shortlisted. In total, 18 questions were shortlisted for the final workshop, the maximum number considered feasible by the steering group for effective discussion online.

2.7. Final workshop—agreeing the top 10

The final stage involved a 1‐day workshop (2 October 2020) using the established JLA approach, which was adapted to be delivered online. 14 Twenty‐five participants were identified initially through phased targeted approaches to prioritise representation from ethnic minority groups, the devolved nations and Crown dependencies, support networks and specific health professions, for example, psychologists and GPs as underrepresented groups, followed by open invitation. Contacts collated through the surveys, and special interest groups and partner communication channels were used. Participants were screened for possible conflicts of interest and whether they were highly research active in the area. The participants were split into four breakout groups balanced by representation between women, support networks and healthcare professionals, and by experience of diabetes and healthcare specialist.

In breakout groups, the attendees participated in a series of discussion and ranking exercises to jointly rank the shortlist of indicative questions and agree the top 10 most important for future research to answer. The workshop and discussions were facilitated by trained JLA advisors to ensure equal and open participation. Four steering group members joined as observers only. Technical support was made available, and a contact point for emotional support was provided should any participant be upset by the process or discussions. The participants were invited to provide anonymous feedback on the prioritised questions and the workshop generally.

2.8. Ethics

The Medical Sciences Interdepartmental Research Ethics Committee, University of Oxford confirmed that the project did not require ethics committee approval.

The top 10 areas of most needed research in diabetes and pregnancy identified were: diabetes technology at any stage pre‐ to post‐pregnancy, the best test for diabetes during pregnancy, diet and lifestyle interventions for diabetes management during pregnancy, emotional and well‐being needs of women with diabetes pre‐ to post‐pregnancy, safe birth at full term, post‐natal care and support needs of women, diagnosis and management late in pregnancy, prevention of other types of diabetes in women with gestational diabetes, women's labour and birth experiences and choices and improving planning for pregnancy (Table  2 ).

Top 10 priorities for research in diabetes and pregnancy according to women, their support networks and healthcare professionals

The indicative questions are presented in final rank order, with phase of pregnancy, the question concerns, the number of initial survey questions grouped within the indicative question and the interim survey ranking results by group; HCPs ‐ Healthcare professionals; T1D – Type 1 diabetes; T2D – Type 2 diabetes; GDM – Gestational diabetes mellitus.

The responses at each stage of the process are summarised in Figure  1 . Participant demographics at each stage of the process are in Table  3 . The survey submission counts and rankings for the 60 indicative questions are available in Supplementary Table  S2 .

Summary of the James Lind Alliance prioritisation process showing how the top 10 questions in diabetes and pregnancy were identified. ^Ongoing studies were not included as evidence as it would not be possible to know if they answer the question

Participant demographics at each stage of the priority setting process

3.1. Initial survey

Four hundred and sixty‐six responses were submitted (64% women and support networks, 32% healthcare professionals and 4% other/not answered) suggesting 1161 questions covering the whole perinatal period (Supplementary Table  S3 ).

Initial questions submitted by women and support networks were mainly in relation to post‐birth effects on themselves and their child, diabetes management during pregnancy and understanding the risks for diabetes in pregnancy. The long‐term effects of diabetes in pregnancy on the child (risks of the child developing diabetes and any wider health effects) being the most frequently asked question (20.1% of women and support networks’ submissions). This group more specifically raised questions about breastfeeding (8.9%) and labour and birth (8.6%) in terms of informed choice, continuity/availability of care and emotional support more generally. Healthcare professionals’ questions were mainly about pre‐pregnancy care, and diagnosis and clinical management of diabetes in pregnancy. How to improve preconception care was most frequently asked (9.7% of healthcare professionals’ submissions), closely followed by the value and methods of diagnosis and management of diabetes late in pregnancy, that is, after 34 weeks (8.5%). Modes of delivering care, improving uptake and access to services and motivational interventions were more specifically raised by this group. Common to both groups were questions about individualised and risk‐based care, optimal management of diabetes, prevention of diabetes and safety of medications.

One hundred and forty‐two categories were extracted and broadly organised by the phase of pregnancy: pre‐pregnancy (62 questions, 6.3%), pregnancy (376, 38.2%), labour and birth (87, 8.8%) and post‐birth (373, 37.9%). Technology (20, 2.0%), mental health and well‐being (20, 2.0%) and health services (46, 4.7%) were identified as cross‐cutting categories. A total of 934 questions were within scope, of which 50 mapped to more than one category, and consolidated into 60 indicative questions. Rarely was there a need to specify a type of diabetes within an indicative question, which reflects the significant overlap in priorities regardless of diabetes type. The main distinctions were questions relating to gestational diabetes, due to its transient nature and diagnosis in pregnancy. All 60 indicative questions were considered to have substantial uncertainty following evidence checks. The evidence check summary is provided in Supplementary Table  S4 .

3.2. Interim survey

Six hundred and fourteen submissions (80% women and support networks and 20% healthcare professionals) were received in the interim survey. In the interim survey rankings, there were notable differences between women and support networks, and healthcare professionals (Figure  2a ). Four of the top 10 ranked questions for healthcare professionals were below the 45th ranking for women and support networks. Women and support networks ranked the long‐term effects of diabetes in pregnancy on the child's general health (non‐diabetes‐related) highest. Varying standards and advice across hospitals and giving birth at full term were also in the top three.

Interim survey question ranking comparisons between respondent groups. (a) Main groups: Indicative questions are ordered by rank position for women and support networks (60th to 1s t place; left to right). (b) Diabetes type: Indicative questions are ordered by rank position for the group that indicated interest/experience in gestational diabetes (60th to 1st place; left to right). ‘Other’ types were grouped with type 2 diabetes due to low number and greatest similarity in rankings. T1D – Type 1 diabetes; T2D – Type 2 diabetes; GDM – Gestational diabetes mellitus

Voting patterns varied for the main groups between surveys (Figure  3 ) with overall movement towards labour and birth and cross‐cutting categories. For example, despite being rarely asked in the initial survey, the use of technology became the highest ranked for healthcare professionals in the interim survey.

Survey submissions by main group. The initial and interim survey submissions for women and support networks, and healthcare professionals proportioned by phase of pregnancy

For ethnic minorities, representation was below national population figures for Black and Black British groups in both surveys (1.6% and 0.5% respectively; national 3.0%), and for Asian and Asian British groups (4.1%; national 7.0%) in the interim survey. With low numbers, the votes across 60 questions became too dispersed to discern a strong pattern. However, peaks in voting overlapped the top 10 for women and support networks, and healthcare professionals, with the eight highest voted questions already shortlisted for the final workshop.

Comparing the interim survey rankings by types of diabetes, there were some clear differences (Figure  2b ). Technology was ranked the top priority for type 1 and type 2/other diabetes groups, but ranked low for the gestational diabetes group. Post‐birth support came in second for type 1, but ranked low for both type 2/other and gestational diabetes groups, whereas testing for diabetes during pregnancy and prevention of developing diabetes ranked high for type 2/other and gestational diabetes groups but low for the type 1 diabetes group.

3.3. Final workshop and top 10

The diversity and balance in experiences and expertise of workshop attendees were strong (Table  3 ). Participants uncovered unexpected overlaps between questions, for example, technology for diabetes care was considered to include telemedicine which was subsequently ranked lower; labour and birth choices was considered to overlap with safety of giving birth at full term and the need for induction. Groups also highlighted recurring themes that linked with multiple questions. For example, technology was considered to improve understanding of diabetes management and reduce burden, linking with mental health and well‐being. Therefore, with further such links highlighted, both these questions were more highly ranked as the discussions progressed.

Consistently, top ranking questions through the surveys were regarding the long‐term health impact of maternal diabetes on the child. The questions submitted in the initial survey were clearly split into risk of the child developing diabetes or the risk of wider health conditions. Ranking in the top 10 of all groups, both questions were shortlisted for the final workshop. However, neither reached the final top 10 (positions 11 and 12 respectively). Workshop discussions and post‐workshop feedback from participants indicated several reasons for this apparent discrepancy. Firstly, the questions were considered to be addressed within the broader research agenda of child health, and not necessarily within pregnancy or women's health. The other questions all affected or contributed to the child outcomes, so it was felt they would help address these questions too. Some participants considered that the answers to the questions about long‐term child outcomes would add burden to women already concerned by many factors associated with dealing with the responsibility of a pregnancy and diabetes. For some, ‘how can it be prevented’ was important wording, as it balanced the concerns of adding burden of information on risks, with learning about what can be done to prevent these being realised. One of the questions did not include the specific wording about prevention and so was ranked less highly. A further possible reason for these questions receiving less priority was because the votes were split; if presented as a single question, this may have meant a higher final ranking. A final possible reason may have been that the workshop consisted of people with recent experience, that is, within the last five years.

Feedback was received from 10 women and support network representatives, and 10 healthcare professionals from the workshop:

‘It was really good having different perspectives. Moving to a second smaller group was also useful, as it showed how varied priorities can be between 2 groups, despite having a similar mix of people from the different backgrounds’ ‘Although the final top 10 was not the same as my personal top 10 that I had prepared, discussing all of the 18 questions, and reflecting on them as a group, meant I was satisfied with it. It was good to hear the views of women with different forms of diabetes and look at the questions from their perspective’ .

Further excerpts of the feedback and the JLA’s review of the online format of the workshop are available at www.jla.nihr.ac.uk/development‐of‐online‐priority‐setting‐workshop.htm .

4. DISCUSSION

4.1. main findings.

We supported women, their support networks and healthcare professionals to jointly identify the top 10 questions for research in diabetes and pregnancy. The final list includes priorities of relevance to all the stakeholders, all types of diabetes and preconception to long‐term post‐pregnancy. These questions were generated through a robust and inclusive process, which can be trusted and used by funders of research and researchers to inform their research activities towards addressing evidence gaps of great need and impact.

There is consistency across many areas also identified by the modified prioritisation exercises in Canada and the USA focussing on gestational diabetes, such as screening, risk factors, prevention and clinical management of diabetes in the woman. 10 , 11 For example, whether there is a better test for diabetes during pregnancy than the oral glucose tolerance test was ranked joint first for similar reasons of application, interpretation and practicality, with no apparent consensus on the thresholds, methods and timing to test for diabetes in pregnancy, due to small‐sized studies. Our participants raised further questions such as the possible use of testing to predict gestational diabetes, the stratification of testing by risk and testing within special populations, such as those who have undergone gastric bypass surgery, and open up further opportunities for research.

There are also some clear differences in priorities including preconception care, late pregnancy diagnosis, labour and birth experiences and post‐natal care needs, particularly breastfeeding. The role of diabetes technology was ranked joint first position, and while explicably not featuring in the gestational diabetes exercises, technology‐specific questions formed the top three of the JDRF UK type 1 diabetes PSP final top 10. There have been significant developments in diabetes technology in the last few years with ongoing innovations. 16 In the time since the final workshop, the National Institute of Clinical Excellence has completed their review and approved the funding of continuous glucose monitoring for pregnant women with type 1 diabetes, in line with The NHS Long Term Plan . 17 , 18 However, our results endorse their recommendations for further large‐scale research in different monitoring methods and systems (i.e. insulin pumps) in women with diabetes of different types, through all stages preconception to post‐pregnancy, and importantly with wider population diversity. There are also wider facets to consider such as apps, automation, data integration platforms and data sharing in supporting the management of diabetes.

Risks to the child's health was the number one priority identified by women in the Canadian exercise, and ranked highest in the USA exercise, but strikingly fell outside our top 10. However, the possible reasons for this, based on differential prioritisation of two related summary questions, made clear that the impact on the child is still considered highly important for separate study.

Important overarching issues were noted around continuity of care and support (particularly post‐birth), consistency in care standards and advice, joint decision making (particularly in labour and birth) and the burden for women of being diagnosed with and managing diabetes. The consequences on women's well‐being and mental health were at the core of much of the discussion at the final workshop. The initial survey submissions also raised further unanswered questions about the impact of a ‘medicalised’ pregnancy, withdrawal of intensive clinical involvement postpartum and support needs of women if adverse outcomes in their child linked to diabetes are realised. There is ongoing lack of evidence on the support pregnant women with diabetes may need as previously echoed by the gestational diabetes prioritisation exercises. However, the Diabetes UK Too Often Missing report highlights pregnancy as a time of particular high risk for emotional and psychosocial impact of diabetes requiring increased awareness and support. 19

5. STRENGTHS AND LIMITATIONS

This is the first priority setting exercise to focus on all different types of diabetes and at any stage before, during and after pregnancy, including long‐term post‐pregnancy.

The initial survey was completed in 2019 before the Covid‐19 pandemic and lockdowns, but the interim prioritisation survey and final workshop took place during the pandemic over 2020. Due to the restrictions, the interim survey and final workshop could only be completed online. Despite an increased response rate in the interim survey, the online‐only nature will have imposed limitations on who could take part. Reliance on online‐only means of communication and participation may also have affected outreach, particularly to ethnic minority groups, which was achieved in the initial survey mainly through the support of community champions and face‐to‐face approaches in hospital clinics. However, despite our best efforts, representation was below what may be expected based on national population statistics, particularly Black and Black British groups. 20 Therefore, the results may not be representative of the priorities of ethnic minority groups.

Although the indicative questions were established before the 2020 Covid‐19 pandemic, it is possible that the voting in the interim survey and, consequently, the shortlist of questions for the final workshop have been influenced. The final workshop participants were advised to consider the shortlisted questions thinking longer term beyond the pandemic so that this would not unduly influence the results for the future. More generally, it is not assured that if the exercise was redone that the same priorities would be identified and assigned the same rank.

6. CONCLUSIONS

Further research is needed to provide evidence‐based healthcare for women, with or at risk of diabetes complications, who are planning pregnancy or are pregnant, to ensure the best outcomes for them and their children in the short and long term.

The Covid‐19 pandemic has highlighted the importance of inclusive research. Pregnant women, those planning pregnancy or breastfeeding are often actively excluded from clinical trials, perpetuating the population as a vulnerable group. 21 The addition of co‐morbidities, such as diabetes, complicates matters further. As well as improved health and well‐being for generations of families, interventions which improve outcomes for pregnancy with diabetes provide significant opportunity in terms of cost savings. 13

The questions identified are areas that still have significant uncertainty and are considered to be of most importance by the beneficiaries of that research. This work presents further opportunity for funders and researchers to focus future research to address the priorities of women, support networks and health professionals.

CONFLICT OF INTEREST

GA, FA, IB, NB, CB, SC, DC, KC, JG, MK, JLZ, FM, RM, NM, AM, JO, NR, CS, KS, AS and JAS none declared. JEH is a member of the NICE Diabetes Committee and holds a UKRI Future Leaders fellowship. HRM sits on a scientific advisory board for Medtronic (insulin pump and CGM manufacturer) and has received research support from Medtronic, Dexcom and Abbott Diabetes Care Inc. (CGM devices). MWJS has received honoraria from Astellas, AstraZeneca, Eli Lilly, Merck, Sanofi, Eisai and Bristol Myers Squibb, and has contributed to advisory boards for Novo Nordisk, Eisai and Servier.

AUTHOR CONTRIBUTIONS

GA and MK conceived the idea for the project and led the PSP. GA had full access to the data, coordinated the PSP process, drafted the surveys, analysed and led the interpretation of the data and wrote the first draft of the manuscript. GA, FA, IB, NB, CB, SC, DC, KC, MD, JG, JH, MK, AM, HM, JO, CS, KS, AS and MS are members of the Diabetes and Pregnancy Priority Setting Partnership (PSP) steering group and were responsible for the development of the protocol, and conduct, integrity and oversight of this work. All steering group members contributed to the outreach and communication activities to maximise participation and awareness. KC facilitated and chaired the PSP process, steering group and final workshop. GA, JS, NM, NR, RM, JL‐Z, FM and MK completed the evidence checks. MK and KC are joint senior authors. All authors reviewed and approved the manuscript and revised it for intellectual content.

Supporting information

Acknowledgements.

The project team thank everyone who contributed through the surveys and took part in the final workshop, our experts by experience steering group members, Rachel Connor, JDRF UK, and Lucy McKillop, University of Oxford, who were advisors to the steering group, our partners and the many people and organisations who supported at various stages throughout the project, sharing their time, expertise, communications and meeting facilities, without whom this project would not have been successful.

Marian Knight and Katherine Cowan should be considered joint senior authors.

The Diabetes and Pregnancy Priority Setting Partnership was funded by Diabetes Research and Wellness Foundation (SCA/PP/12/19), and John Fell Fund and Nuffield Department of Population Health, University of Oxford. The funders had no involvement in the design, conduct, analyses and interpretation of data, or the reporting and submission of results of this project. MK is an NIHR Senior Investigator. The views expressed in this article are those of the author(s) and not necessarily those of the NIHR, or the Department of Health and Social Care.

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Latest List of Best Diabetes Dissertation Topics

Published by Owen Ingram at January 2nd, 2023 , Revised On May 17, 2024

The prevalence of diabetes among the world’s population has been increasing steadily over the last few decades, thanks to the growing consumption of fast food and an increasingly comfortable lifestyle. With the field of diabetes evolving rapidly, it is essential to base your dissertation on a trending diabetes dissertation topic that fills a gap in research. 

Finding a perfect research topic is one of the most challenging aspects of dissertation writing in any discipline . Several resources are available to students on the internet to help them conduct research and brainstorm to develop their topic selection, but this can take a significant amount of time. So, we decided to provide a list of well-researched, unique and intriguing diabetes research topics and ideas to help you get started. 

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List of Diabetes Dissertation Topics

• Why do people recently diagnosed with diabetes have such difficulty accepting reality and controlling their health?
• What are the reactions of children who have recently been diagnosed with diabetes? What can be done to improve their grasp of how to treat the disease?
• In long-term research, people getting intensive therapy for the condition had a worse quality of life. What role should health professionals have in mitigating this effect?
• Why do so many individuals experience severe depression the months after their diagnosis despite displaying no other signs of deteriorating health?
• Discuss some of the advantages of a low-carbohydrate, high-fat diet for people with diabetes
• Discuss the notion of diabetes in paediatrics and why it is necessary to do this research regularly.
• Explain the current threat and difficulty of childhood obesity and diabetes, stressing some areas where parents are failing in their position as guardians to avoid the situation
• Explain some of the difficulties that persons with diabetes have, particularly when obtaining the necessary information and medical treatment
• Explain some of the most frequent problems that people with diabetes face, as well as how they affect the prevalence of the disease. Put out steps that can be implemented to help the problem.
• Discuss the diabetes problem among Asian American teens
• Even though it is a worldwide disease, particular ethnic groups are more likely to be diagnosed as a function of nutrition and culture. What can be done to improve their health literacy?
• Explain how self-management may be beneficial in coping with diabetes, particularly for people unable to get prompt treatment for their illness
• Discuss the possibility of better management for those with diabetes who are hospitalised
• What current therapies have had the most influence on reducing the number of short-term problems in patients’ bodies?
• How have various types of steroids altered the way the body responds in people with hypoglycemia more frequently than usual?
• What effects do type 1, and type 2 diabetes have on the kidneys? How do the most widely used monitoring approaches influence this?
• Is it true that people from specific ethnic groups are more likely to acquire heart disease or eye illness due to their diabetes diagnosis?
• How has the new a1c test helped to reduce the detrimental consequences of diabetes on the body by detecting the condition early?
• Explain the difficulty of uncontrolled diabetes and how it can eventually harm the kidneys and the heart
• Discuss how the diabetic genetic strain may be handed down from generation to generation
• What difficulties do diabetic people have while attempting to check their glucose levels and keep a balanced food plan?
• How have some individuals with type 1 or type 2 diabetes managed to live better lives than others with the disease?
• Is it true that eating too much sugar causes diabetes, cavities, acne, hyperactivity, and weight gain?
• What effect does insulin treatment have on type 2 diabetes?
• How does diabetes contribute to depression?
• What impact does snap participation have on diabetes rates?
• Why has the number of persons who perform blood glucose self-tests decreased? Could other variables, such as social or environmental, have contributed to this decrease?
• Why do patients in the United States struggle to obtain the treatment they require to monitor and maintain appropriate glucose levels? Is this due to increased healthcare costs?
• Nutrition is critical to a healthy lifestyle, yet many diabetic patients are unaware of what they should consume. Discuss
• Why have injuries and diabetes been designated as national health priorities?
• What factors contribute to the growing prevalence of type II diabetes in adolescents?
• Does socioeconomic status influence the prevalence of diabetes?
• Alzheimer’s disease and type 2 diabetes: a critical assessment of the shared pathological traits
• What are the effects and consequences of diabetes on peripheral blood vessels?
• What is the link between genetic predisposition, obesity, and type 2 diabetes development?
• Diabetes modifies the activation and repression of pro- and anti-inflammatory signalling pathways in the vascular system.
• Understanding autoimmune diabetes through the tri-molecular complex prism
• Does economic status influence the regional variation of diabetes caused by malnutrition?
• What evidence is there for using traditional Chinese medicine and natural products to treat depression in people who also have diabetes?
• Why was the qualitative method used to evaluate diabetes programs?
• Investigate the most common symptoms of undiagnosed diabetes
• How can artificial intelligence help diabetes patients?
• What effect does the palaeolithic diet have on type 2 diabetes?
• What are the most common causes of diabetes and what are the treatments?
• What causes diabetes mellitus, and how does it affect the United Kingdom?
• The impact of sociodemographic factors on the development of type II diabetes
• An examination of the link between gut microbiome and diabetes risk
• The effectiveness of lifestyle interventions in preventing type II diabetes
• The role of maternal diabetes in offspring’s risk of developing diabetes
• Artificial intelligence in diabetes diagnosis and management
• Continuous glucose monitoring
• Telehealth interventions for improving diabetes self-management
• The role of wearable technology in diabetes management
• Personalised medicine approaches for diabetes treatment
• The impact of diabetes on mental health and well-being
• The link between diabetes and cognitive decline
• The potential of stem cell therapy for diabetes treatment
• Advances in closed-loop insulin delivery systems
• The use of glucagon-like peptide-1 (GLP-1) receptor agonists in diabetes treatment
• Investigating the efficacy of new oral medications for type II diabetes
• The role of bariatric surgery in the management of type II diabetes
• Improving patient adherence to diabetes treatment regimens
• The role of social support in diabetes management
• Developing culturally sensitive diabetes education programs
• The role of dietary patterns in diabetes prevention and management
• Low-carbohydrate vs. Mediterranean diet for diabetes: A comparative study
• The use of artificial sweeteners in diabetes management: Benefits and risks
• The impact of the gut microbiome on dietary interventions for diabetes
• The role of exercise in improving glycemic control
• Developing effective exercise programs for individuals with diabetes
• The impact of physical activity on diabetic complications
• Promoting physical activity adherence in people with diabetes
• The use of exercise gamification to increase physical activity in diabetes
• The potential of CRISPR gene editing for diabetes treatment
• The role of the microbiome in the development and treatment of diabetes
• An analysis of the artificial Pancreas systems
• The use of big data analytics in diabetes research
• The impact of environmental factors on diabetes risk
• Cost-effectiveness of different diabetes treatment strategies
• Developing effective diabetes prevention programs for communities
• The role of government policies in addressing the diabetes epidemic
• Improving access to diabetes care in underserved populations
• The impact of social determinants of health on diabetes risk
• Management of diabetes in children and adolescents
• The unique challenges of diabetes management in older adults
• Diabetes in ethnic minorities: Disparities in prevalence and care
• The impact of diabetes on LGBTQ+ populations

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You can contact our 24/7 customer service for a bespoke list of customised diabetes dissertation topics , proposals, or essays written by our experienced writers . Each of our professionals is accredited and well-trained to provide excellent content on a wide range of topics. Getting a good grade on your dissertation course is our priority, and we make sure that happens. Find out more here . 

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To find diabetes dissertation topics:

• Study recent research in diabetes.
• Focus on emerging trends.
• Explore prevention, treatment, tech, etc.
• Consider cultural or demographic aspects.
• Consult experts or professors.
• Select a niche that resonates with you.

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