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Sheridan Grant

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Sheridan is a writer from Hamilton, Ontario. She has a passion for writing about what she loves and learning new things along the way. Her topics of expertise include skincare and beauty, home decor, and DIYing.

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About Thesis Nootropics

Thesis Nootropics Review

Hands up if you guzzle five coffees a day to stay awake, have tried all the supplements in the book desperate to improve your headspace, and aren’t interested in prescribed medications. Designed to increase focus , Thesis nootropics might be for you. 

Thesis offers a customized blend of ingredients designed to optimize your cognitive function , with personalized details that tackle your specific needs. Nootropics boost brain performance in the same way a stimulant would, without the common negative effects. 

A study published in the Journal of Alzheimer’s Disease found that nootropics may help improve cognitive function in people with Alzheimer’s disease.

Interested in finding out more about the brand and how it works? Leaf through our Thesis Nootropics review. We’ll be your guide through the company and the process, as well as details on the treatments, highlights from customer reviews, answers to important FAQs, and more, to help you decide if it’s worth the try.

Pros and Cons

Thesis Nootropics Review

  • Multiple cognitive benefits: Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function.
  • Long-term effects: On top of short term benefits for daily life, Thesis nootropics ingredients are designed to impact the brain in the long-term.
  • Personalized recommendations: Thesis Nootropics makes personalized recommendations based on your goals and unique brain chemistry.
  • Potential side effects: The most common side effects to watch out for when you start taking Thesis Nootropics include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
  • Need to stop taking if issues arise: If you experience a headache or an upset stomach that won’t go away while taking their nootropics, Thesis recommends that you stop taking them.

What is Thesis Nootropics?

Thesis Nootropics Review

Nootropics are nutrient compounds and substances that are known to improve brain performance , such as caffeine and creatine. They help with issues that affect motivation, creativity, mood, memory, focus, and cognitive processing.

Nootropics are the ideal addition to an already healthy lifestyle that consists of exercise, proper nutrition, and enjoyable activities.  Thesis nootropics are carefully formulated to target specific needs, ranging from energy to creativity. The brand focuses on safety, ensuring that all supplements adhere to FDA guidelines and go through multiple clinical trials. 

How Thesis Nootropics Works

Thesis Nootropics Review

With all that being said, you may be wondering how Thesis provides users with an option that is specific to their needs. Fortunately, the process is simple and hassle free. Here’s how it works:

  • Take the Thesis nootropics quiz
  • Answer questions about your basic information
  • Receive personalized recommendations 
  • Get your starter kit for $120 , or $79 monthly when you subscribe 

After that, you’ll select one formula to take each week, taking one day off in between each different option. You’ll also track your results in the daily journal over the month to see how they affect your daily life. 

From there, it operates as a subscription service. Users will be able to optimize their next shipment by telling the brand which formulas worked best.

If you don’t like any of the blends in your box, let the company know and they’ll switch it for something that’s a better fit for your lifestyle, genetics, and goals.

Thesis Nootropics Ingredients

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties. Here are some of the key ingredients in Thesis Nootropics:

  • Cognizin (Citicoline) : Cognizin is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
  • L-Theanine : L-Theanine is an amino acid that is found in green tea, and is known for its ability to promote relaxation and reduce stress and anxiety.
  • Lion’s Mane Mushroom : Lion’s Mane Mushroom is a type of medicinal mushroom that is believed to have cognitive-boosting properties, including improved memory and focus.
  • Rhodiola Rosea : Rhodiola Rosea is an adaptogenic herb that is known for its ability to reduce stress and fatigue, and improve mental clarity and cognitive function.
  • Ashwagandha : Ashwagandha is an adaptogenic herb that is known for its ability to reduce stress and anxiety, and improve memory and cognitive function.
  • Phosphatidylserine : Phosphatidylserine is a type of phospholipid that is found in high concentrations in the brain, and is believed to support cognitive function, including memory and focus³
  • Alpha-GPC : Alpha-GPC is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
  • TAU (uridine): TAU is a blend of uridine, choline, and DHA, which is believed to support brain health and cognitive function.
  • Artichoke extract : Artichoke extract is believed to enhance cognitive function by increasing levels of acetylcholine, a neurotransmitter that is important for memory and learning.
  • Dynamine : Dynamine is a type of alkaloid that is believed to enhance cognitive function by increasing levels of dopamine, a neurotransmitter that is important for mood and motivation.

Overall, the ingredients in Thesis Nootropics are carefully chosen for their cognitive-boosting properties, and are designed to work together to enhance overall brain health and cognitive function.

Thesis Nootropics Health Benefits

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties, and offer numerous health benefits. Here are some of the health benefits of Thesis Nootropics:

  • Increased cognitive energy : One of the key benefits of Thesis Nootropics is increased cognitive energy, which can help improve productivity, mental alertness, and motivation, as it contains cognizin .
  • Enhanced mental clarity : Another benefit of Thesis Nootropics is enhanced mental clarity,given from Lion’s Mane Mushroom which can help reduce brain fog and improve focus.
  • Improved memory and learning abilities : Thesis Nootropics contains ingredients that are believed to improve memory and learning abilities, like Phosphatidylserine , which can help users retain information more effectively.
  • Elevated mood : Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression, thanks to ingredients like L-Theanine and Ashwagandha .
  • Lowered stress levels : The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha , are known for their ability to lower stress levels and promote relaxation.
  • Boosted focus : Thesis Nootropics contains ingredients like Alpha-GPC and Artichoke extract , which are believed to boost focus and concentration.

While Thesis Nootropics offers numerous health benefits, it’s important to note that the long-term effects of nootropics are not yet fully understood and more research is needed.

3 Thesis Nootropics Bestsellers

Thesis energy review.

Thesis Energy Review

If you’re constantly struggling to keep up with the demands of your busy life, it might be time to try a natural energy booster like Thesis Energy. This powerful nootropic blend is specifically designed to increase energy, overcome fatigue, and build mental stamina.

Thesis Energy is caffeine-free, making it a great option for those who are sensitive to caffeine or looking for a natural alternative to traditional energy drinks. The Energy formulation is designed to help improve focus and mental clarity, increase cognitive energy, and reduce fatigue. Whether you’re facing a busy day at work, recovering after a night of poor sleep, or gearing up for an intense workout, Thesis Energy can help you power through.

Each ingredient in Thesis Energy is carefully chosen for its energy-boosting properties. The specific ingredients can vary depending on your needs, but they work together to help increase energy, improve mental clarity, and reduce fatigue.

To get the most out of Thesis Energy, take it every morning on an empty stomach. You can also take it again after lunch if you need an extra boost. It’s designed to help you tackle busy, hectic days, recover from poor sleep, and power through intense workouts.

If you’re tired of relying on coffee and energy drinks to get through the day, it might be time to give Thesis Energy a try. Check availability and start boosting your energy naturally today!

Thesis Creativity

Thesis Nootropics

If you’re someone who struggles with creativity or finds yourself feeling stuck in your creative endeavors, Thesis Creativity may be worth considering. This nootropic supplement is designed to help spark inspiration, enhance verbal fluency, and boost confidence in your own great ideas.

So what’s in Thesis Creativity? The ingredients may vary depending on your specific needs, but these ingredients work together to support stress management, memory function, mood regulation, and energy production.

By supporting stress management, memory function, and mood regulation, Thesis Creativity can help free up mental space for more creative thinking. Additionally, the caffeine and L-theanine combo can provide a boost of energy and focus without the jitters and crash that can come with caffeine alone.

To get the most out of Thesis Creativity, it is recommended to take it every morning on an empty stomach and again after lunch if you need an extra boost. This nootropic blend is particularly helpful for brainstorming and creative thinking, writing and creative projects, and public speaking and social situations.

As with any nootropic supplement, it’s important to note that the long-term effects of Thesis Creativity are not yet fully understood and more research is needed. It’s always a good idea to speak with a healthcare professional before adding any new supplements to your routine.

In summary, if you’re looking for a little extra help in the creativity department, Thesis Creativity may be a valuable addition to your nootropic lineup. Its unique blend of ingredients can help support mental clarity, mood regulation, and energy production, making it a valuable tool for any creative individual.

Thesis Logic

Thesis Logic Review

If you’ve been having trouble with your memory lately, such as forgetting what you had for lunch yesterday or struggling to recall common words, then Thesis Logic may be just what you need. This formula is designed to help enhance your processing speed, boost your memory, and deepen your thinking.

Thesis Logic is caffeine-free, making it a great option for those who are sensitive to caffeine. The formula is ideal for use during deep, focused work, complex problem-solving, research projects, and completing tedious tasks.

Taking Thesis Logic is easy – simply take it every morning on an empty stomach, and take it again after lunch if you need an extra boost. By incorporating Thesis Logic into your daily routine, you may notice improvements in your cognitive function and overall mental performance.

Who Is Thesis Nootropics For? 

Thesis Nootropics Review

Thesis nootropics are designed for a number of different specific needs, including anyone who wants to focus better, have more energy, and maintain mental clarity. All in all, the products are specifically formulated to improve day to day life and target your specific needs .

Thesis Nootropics Side Effects

Thesis Nootropics Review

While Thesis nootropics are designed to enhance cognitive performance and provide a range of benefits, it’s important to be aware of the potential side effects that can occur. As with any supplement, individual reactions can vary, and some people may experience side effects while others may not.

Some of the potential side effects of Thesis nootropics include:

  • Insomnia : Some nootropics contain caffeine or other stimulants that can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
  • Blurry vision : Certain nootropics, such as those containing alpha GPC, have been linked to temporary blurry vision.
  • High blood pressure : Stimulant-based nootropics can increase blood pressure, which can be dangerous for people with hypertension or other heart conditions.
  • Fast heart rate : Similarly, stimulants can also increase heart rate, leading to palpitations or a rapid pulse.
  • Circulation problem s: Certain nootropics, such as vinpocetine, can affect blood flow and circulation, leading to issues like dizziness, nausea, or headaches.
  • Addiction : Some nootropics, such as those containing racetams, have been associated with the potential for addiction or dependence if used long-term.

It’s important to remember that not all nootropics will produce these side effects, and the severity of any reactions will depend on individual factors such as dosage, duration of use, and underlying health conditions. However, it’s always wise to discuss any potential risks with a healthcare professional before starting any new supplement regimen.

Additionally, it’s important to follow dosage instructions carefully and not to exceed recommended amounts, as this can increase the risk of side effects. By being mindful of potential risks and using nootropics responsibly, users can reap the benefits of these supplements without experiencing adverse effects.

Thesis Nootropics Reviews: What Do Customers Think?

Thesis Nootropics Review

At this point in our Thesis nootropics review, it’s time to turn to what customers are saying. So, we sourced testimonials from the brand’s website, Reddit, and ZenMasterWellness. And spoiler alert, the Thesis nootropics reviews we came across have nothing but good things to say.

On takethesis.com , the brand earns 4.4/5 stars out of 7,956 reviews. One patron describes their particular blend as the perfect alternative to prescription meds :

“ I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work .”

On Reddit, many reviewers share similar sentiments about how effective the products are. One buyer shares that they tried tons of different nootropics on the market, and Thesis stands out amongst the crowd . 

On ZenMasterWellness, one reviewer states that their blend provided the exact results they were looking for :

“ They offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out .”

Backed by clinical trials and real customer experiences, Thesis stands out in the world of nootropics and supplements. The personalized selections prove effective, while the quality ingredients live up to expectations. 

Is Thesis Nootropics Legit?

Thesis Nootropics Review

If you’re wondering if this brand offers products that are too good to be true, this Thesis nootropics review is here to say that it is the real deal .

The brand is backed by numerous clinical trials, which highlight how 86% of customers reported improvements in a wide range of cognitive challenges, while 89% noticed an improvement in their ability to reduce stress and maintain energy.

Is Thesis Nootropics Worth It?

Thesis Nootropics Review

Thesis is an appealing choice in the world of nootropics because it provides a completely customized selection based on your needs and goals. Plus, the ingredients are potent and ensure the best effects—and you only end up paying for the benefits you actually need.

With that in mind, this Thesis nootropics review deems the brand worth the try.

Alternatives

Here are some alternatives to Thesis Nootropics that you might find interesting:

  • Mind Lab Pro – This nootropic supplement is designed to improve cognitive function and mental performance. It contains 11 ingredients that work together to enhance memory, focus, and overall brain health.
  • Thorne Supplements : If you’re looking for high-quality, science-based supplements, Thorne is a great choice. Their products are designed with the latest research in mind and are rigorously tested for quality and purity. Some of their popular offerings include multivitamins, protein powders, and omega-3 supplements.
  • WeAreFeel Supplements : WeAreFeel is a supplement brand that offers a variety of products designed to support different aspects of your health. Their supplements are vegan-friendly and free from artificial colors, flavors, and preservatives. Some of their popular offerings include multivitamins, probiotics, and omega-3 supplements.
  • Neuro Gum : If you’re looking for a quick and easy way to boost your focus and energy levels, Neuro Gum is a great option. This gum is infused with caffeine and other natural ingredients that can help improve mental clarity and alertness. Plus, it’s sugar-free and comes in a variety of delicious flavors.
  • Neuriva Plus : Neuriva Plus is a brain supplement that’s designed to improve memory, focus, and cognitive performance. It contains a blend of natural ingredients, including coffee fruit extract and phosphatidylserine, that have been shown to support brain health. If you’re looking for a natural way to boost your cognitive function, Neuriva Plus is worth considering.

Thesis Nootropics Promotions & Discounts 

Thesis Nootropics Review

There aren’t currently any Thesis promos or discounts available. That being said, if you subscribe for recurring shipments of your recommended products, you’ll save $40 monthly .

Where to Buy Thesis Nootropics

Thesis Nootropics Review

At the time of this Thesis nootropics review, the products are exclusively available on the brand’s website, takethesis.com .

Is Thesis Nootropics vegan?  

Thesis nootropics are made with only vegan ingredients . That being said, while the brand has taken precautions to protect against cross contamination, the products are not certified vegan.

Is Thesis Nootropics gluten-free? 

On top of being vegan, Thesis products are made without gluten, eggs, or nuts . Again, while the brand strives to protect users against cross contamination, the products are not certified gluten free. 

What is Thesis Nootropics’ Shipping Policy?

If you’re anxiously awaiting your order from this Thesis nootropics review, you’ll be happy to hear that the company offers speedy shipping, sending orders out within 1 business day. After that, packages should arrive within only 1-3 business days . Costs are calculated at checkout.

At this time, Thesis is not able to offer international shipping. This Thesis nootropics review recommends following the brand on social media and signing up for the newsletter to stay up to date with shipping policies. 

What is Thesis Nootropics’ Return Policy?

If you find that your Thesis formula isn’t working out, the company requests that you contact them to make changes and adjustments to ensure you are able to receive the proper help.

If you would still like to make a return, follow these simple steps for a refund:

  • Submit your refund request
  • Ship the items back within 30 days of the original delivery
  • Send an email with your tracking number to the brand
  • Return any remaining product in their original packaging to: 

Thesis Returns 902 Broadway

6th Floor New York, NY 

Once your return has been received, a refund will be processed and email confirmation will be sent. It’s also important to note that the brand can only refund one month’s supply per customer and return shipping is the customer’s responsibility. 

How to Contact Thesis Nootropics

We hope you enjoyed this Thesis nootropics review! If you have any further questions about the brand or its products, you can contact them using the following methods:

  • Call 1 (646) 647-3599
  • Email [email protected]

902 Broadway Floor 6 New York, NY 10010

If you’re looking for other ways to boost your productivity via supplements, check out these other brands we’ve reviewed:

Thorne Supplements Review

WeAreFeel Supplements Review

Neuro Gum Review

Neuriva Plus Review

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Thesis Nootropics Review

Thesis has a range of targeted nootropics you can combine to optimize your results. our team will help you decide which ones are right for you..

Daniel Imperiale

Daniel is a senior editor and writer at Innerbody Research. After receiving his bachelor’s degree in writing, he attended post-graduate studies at George Mason University and pursued a career in nutritional science.

Matt Segar, MD

Dr. Segar is a cardiologist at the Texas Heart Institute and a member of Innerbody Research's Medical Review Board.

In this Review

Nootropics in general offer the potential to improve cognitive abilities and regulate mood without the need for a prescription. And while more research is necessary, current data suggests that they consist of ingredients that are generally safe and effective for healthy adults. 35 However, Thesis isn’t the only provider of high-quality nootropics, nor do they offer especially low prices. In this review, we'll compare and contrast Thesis’ six formulas and see how they stack up against a growing field of competitors.

Our Findings

  • You can feel most results within an hour
  • Products are third-party-tested for purity
  • All options available without stimulants
  • Outstanding phone support
  • Subscriptions include complimentary wellness coaching
  • Free shipping on all orders
  • Use code INNERBODY for 10% off your first order
  • Somewhat more expensive than competitors
  • Up to four large pills per dose

Despite the somewhat high price, we recommend Thesis to anyone looking for a nootropic subscription that can be tailored to their specific needs. The formulas from Thesis provide tangible benefits with minimal ingredients, and each formula is available with or without caffeine. Thesis also offers stellar customer service and delivers their product in individually packed doses you can take just about anywhere.

Special Offer: Take 10% OFF with code INNERBODY

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. As nootropics have become more important players in the supplements landscape, we’ve taken a serious look at the key players to see which ones are worthwhile.

Thesis exists in a class of nootropics that combines multiple nootropic ingredients to achieve specific goals. We’ve spent hundreds of hours researching and testing various nootropics, including both individual ingredients and combinations like Thesis offers. In researching Thesis and their competitors, our team has read more than 100 clinical studies examining the efficacy and safety of nootropic ingredients, and we’ve combined all of that knowledge with our experiences to create this review.

If you're curious about our team's experience using Thesis nootropics and wondering how the products will arrive at your door, we made this handy, 5-minute video summarizing those details:

Youtube Video

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

How we evaluated Thesis

To evaluate Thesis, we examined the extensive research available on each ingredient the company uses and compared them to a growing marketplace of nootropics, many of which our testing team has tried over the past few years. Specifically, we assessed how effectively Thesis' formulas work, as well as their safety, cost, and the convenience of acquiring and taking them.

Ultimately, we found Thesis to be one of the more reliable companies in terms of product quality and customer care, even if they are among the more expensive nootropic brands. For any nootropic, you’re looking to create a noticeable effect in brain performance, and altering anything to do with that sensitive chemistry likely warrants a fair investment. The bargain bin is not typically where you want to shop for mind-enhancing substances.

We’ll get into a more direct comparison between Thesis and their competitors a little later, and you’ll see that the balance between their price and overall value is quite reasonable. For now, let’s look at each criterion in more detail.

Effectiveness

Nootropic companies have a plethora of ingredients at their fingertips when they formulate their products. Some companies take a modern approach, focusing on the latest research into established Western medicines. Others look to the past, where ancient Chinese and Ayurvedic practices employed various botanicals to achieve cognitive effects. The best companies combine these approaches, using potentially beneficial ingredients that science supports.

Thesis takes this combined approach, employing just under three dozen ingredients from amino acids to ancient herbs across their six products. The company scores highly in effectiveness thanks to the ingredients they choose and the doses they offer for each, making it likely that you can notice their combined effects.

Individual results will vary due to everything from sleep patterns to diet, but most people should find benefits in at least one of Thesis' six formulas. Caffeinated formulas generally have more pronounced effects than stimulant-free versions, but the value of Thesis offering every formula with or without stimulants cannot be overstated.

One minor knock against Thesis is that, unlike some of their competitors, Thesis does not have a nootropic blend designed for improved sleep. Better sleep supports cognition and mood, so some companies offer formulas designed specifically for sleep promotion with ingredients like melatonin. That said, some of Thesis’ formulas contain lion’s mane or Zembrin (a branded form of Sceletium tortuosum that’s been shown to reduce anxiety and promote sleep). 2 3 And the amount of Zembrin used in Thesis’ Creativity and Confidence blends is the exact same amount used in these successful studies — 25mg.

Good nootropics are, unfortunately, a bit expensive. You can find less expensive options than Thesis, but their $79 monthly rate is right in the middle of what the market demands. You could also argue that the ingredient quality, customization options, and overall efficacy Thesis offers make it a superior value to many less expensive alternatives. Still, the price remains a sticking point for some.

Let's compare the monthly and per-dose costs with some of Thesis' closest competition. The prices below reflect subscription savings where available.

Three of the seven competitors included in the chart above are more expensive than Thesis, and another three are no more than $15 less expensive, revealing their generally average cost. Focus Factor — consistently our top budget pick among nootropics — costs much less than others in the field and includes many ingredients with associated clinical research. The downside is that increasing the number of ingredients (even when they seem to work) increases the odds of an adverse reaction.

TruBrain is the only company that truly compares to Thesis from a quality and variety standpoint. Other companies offer only one or two formulas, whereas Thesis and TruBrain each offer several more targeted products. TruBrain allows you to spend just $69 on your first jar when you subscribe — $10 less than Thesis — but that price shoots up to $119 every month after that, making Thesis the superior value.

When we consider the safety of any supplement, we look at available research into individual ingredients and compare those dosages with what the supplement offers. Whenever possible, we also test the product ourselves to observe its effects on us. Additionally, we look for safety standards in manufacturing that can provide added peace of mind, like third-party testing and compliance with the FDA’s Good Manufacturing Practices (GMP).

Thesis manufactures their products in GMP-compliant facilities and has third-party testing performed to assess the purity of each ingredient and formula. And the clinical research involving the lion's share of their ingredients reveals minimal risk profiles with few to no adverse effects reported. That said, ashwagandha isn’t safe for pregnant or breastfeeding individuals, and it can stimulate thyroid activity, so anyone with thyroid concerns (hyper- or hypothyroidism) or on medication to regulate thyroid function should be careful. 36 37

Thesis also limits their formulas to a handful of ingredients, which reduces the likelihood that any one of them would cause an adverse reaction. This is pretty typical of nootropics in Thesis’ class, but less expensive nootropics might try to convince you of their value by stuffing a single blend with several dozen components. That might increase the chances you feel some positive effect, but the side effect risk goes up by the same token.

Convenience

Our convenience rating considers various aspects of a user's experience. It usually starts with the quality of a product's website design and whether or not its pages are easy to navigate. We also consider the presence of subscription systems that make reordering easier and money-back guarantees that protect your investment. A company's customer service is another vital aspect of convenience, especially if you need questions answered. The quality of an FAQ section, the availability of representatives via chat or phone call, and the responsiveness to email inquiries all play a part here.

Our convenience rating is also informed by the steps required to actually take the product. Nootropics often consist of large capsules, and doses can contain anywhere from 1-7 capsules, which is awful for anyone with difficulty taking pills. Smaller capsules, fewer capsules per dose, and simple dosing schedules are ideal. Thesis’ capsule count varies per formula, ranging from 2-4 mid-size capsules you can take 30 minutes before you might want or need their effects.

To summarize some important aspects of nootropic company convenience, let's look at which companies have large capsule counts, good money-back guarantees, and subscription systems.

Thesis also provides a service that few other companies offer: free consultations with in-house nootropic coaches. These experts can help you figure out the best time to take specific Thesis formulas and guide your experience so you can tell whether or not they're working for you. Follow-up consultations are also free as long as you subscribe to the product.

What are nootropics?

Nootropic is a term most people use to refer to any non-prescription supplement that can boost brainpower. 4 The technical definition is a little more nuanced — encompassing prescription medications like Ritalin and Adderall — but the supplement industry has largely co-opted it to categorize the new class of non-prescription products. The word loosely translates from its Greek origins to mean mind-changing, and the majority of ingredients in a given nootropic seek to alter the brain’s cognitive abilities, as well as its governance of mood and energy.

Most nootropic supplements contain botanical ingredients, vitamins, minerals, and amino acids that boast at least some clinical research connecting them with improvements in any of the following:

Compared to their prescription cousins, nootropic supplements aren't particularly strong. Still, limited clinical research indicates a tangible benefit to taking them.

What is Thesis?

Thesis is a supplement company with a focus on nootropics. Their founders each had experiences growing up with what would today be considered learning disabilities, and they credit nootropics for changing their lives. They make six distinct nootropic formulas, each with a specific ingredient profile.

Thesis differentiates themselves from their competitors in several critical ways:

  • They offer a starter kit containing a personalized combination of four blends.
  • You have the option to remove caffeine by request from any formula.
  • They provide some of the best phone support we've ever experienced.
  • Their targeted formulas conform to changing needs.

By providing you with a mix of formulas, Thesis gives you the ability to enhance the aspects of your cognitive and emotional life that need it the most on any given day. Maybe you know you have low energy levels on Mondays and Wednesdays, so you can take the Energy formula on those days. Maybe you want to devote your weekends to artistic pursuits. You can use the Creativity blend for that. Or you might find that one of their six blends works well for you in any situation. In that case, you can adjust your order to receive only that formula.

Thesis' customer service — particularly over the phone — is outstanding. While many customers might find chat support more convenient, our testers rarely waited more than a minute to speak to someone, and Thesis employs phone operators who are extraordinarily knowledgeable about the product and nootropics in general. Their email support is fine, and their chat support often redirects to an email inquiry. But that phone support is some of the best our testing team has experienced.

Is Thesis safe?

Most of the ingredients that Thesis uses in their nootropics exhibit minimal side effects in clinical research, so there’s a good chance that Thesis' various formulas will be safe for most people. But Thesis has nearly three dozen ingredients in their catalog, and not all of them will be safe for all users, including those who are pregnant or breastfeeding. Of course, the most important thing you can do is talk to your doctor before taking Thesis.

The most common side effects to watch out for when you start taking Thesis nootropics include:

  • Loss of appetite
  • Digestive issues

Thesis advises discontinuing their nootropics if you experience persistent headaches or an upset stomach.

Some Thesis products may present contraindications with certain prescription medicines. For example, ashwagandha has been shown to normalize thyroid hormone levels in people with hypothyroidism. 5 This has led some to believe that it could conversely cause thyrotoxicity in people with hyperthyroidism, though it’s worth noting that the study in question employed double the highest ashwagandha dose you’ll find in Thesis nootropics — the study used 600mg, and the ashwagandha dose in Thesis’ Creativity is 300mg.

Still, this should make abundantly clear the case for speaking with your doctor prior to taking Thesis. This is especially true considering the lack of research into the specific ingredient combinations you’ll find in Thesis products. There is also very little research looking into the risks of combining nootropic supplements with prescription stimulants such as Ritalin, Adderall, or Vyvanse.

Some side effects, such as jitteriness, can be attributed to the caffeine in Thesis formulas. The fact that you can elect to remove caffeine from any formula expands the company’s reach to anyone with caffeine sensitivities and those who really don’t want to give up their morning cup of coffee. If you want caffeine in your Thesis formula, we recommend trying it without having had any coffee first, so you can see how it affects you.

Insider Tip: If you’re not sure whether to get your formula with or without caffeine, we recommend getting it with caffeine. Thesis isolates the included caffeine in a single capsule separate from other ingredients. Caffeinated formulas cost the same as uncaffeinated ones, and you can always elect not to take the caffeine capsule (the smallest capsule in any formula, containing a white powder).

What are the ingredients in Thesis?

Thesis uses an impressive set of ingredients, many of which have been part of respectable clinical research. Not all of the effects they hope these ingredients provide have been proven with sufficient statistical significance or over multiple studies in different populations, but what we do know strongly suggests efficacy.

Here's a look at several Thesis ingredients that have encouraging research behind them:

Several studies on mice show that dihydrohonokiol-B (DHH-B) has potent anxiolytic effects. 6 That means it may be able to help combat anxiety. However, we can’t say this for sure since there haven’t been any studies conducted on humans yet, so any potential benefits are speculative at this time. 25 Converting the successful dose used in mice (1mg) to the equivalent human amount (4.86 mg) is about half the amount used in Thesis’ Confidence (10mg). 6

In numerous studies, ashwagandha has been shown to reduce stress and anxiety. 32 Thesis uses a branded KSM-66 ashwagandha, which has a high standardized count of withanolides — the component of ashwagandha responsible for its positive effects. 33 This ensures both efficacy and consistency from doses that align with those used in successful studies.

While every formula is different, you'll notice that each contains caffeine and L-theanine. The nootropic properties of caffeine are well established. 19 L-theanine — a non-stimulant derived from green tea — has been shown to smooth out the jittery effects of caffeine. You can easily have caffeine removed from any Thesis formula for no extra cost, which is unique in the nootropic market. The L-theanine will remain, as it has its own set of cognitive benefits in addition to its ability to tame caffeine. 20

Saffron offers multiple benefits, including increased levels of dopamine and glutamate, that are dose-dependent. Human studies have also shown positive effects on depression symptoms. Thesis’ Confidence uses 28mg, which is 2mg less than what was used in many of the studies on saffron’s antidepressant effects. However, one study did find success with as little as 15mg. 7

A review of more than 120 scientific articles looking into the cognitive effects of phosphatidylserine concluded that it “safely slows, halts, or reverses biochemical alterations and structural deterioration in nerve cells.” The study goes on to say that it “supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate.” 34

Derived from a South African plant, Zembrin appears to provide cognitive and anti-anxiety effects as demonstrated in clinical studies on human participants that used the same 25mg dose found in Thesis Creativity and Confidence. 8

Synapsa is a patented form of Bacopa extract, a traditional Ayurvedic memory enhancer. Studies on humans resulted in statistically significant improvements in cognitive tests. The study used 150mg twice daily (300mg total), which is only 20mg less than the 320mg used in Thesis’ Logic. 9

7,8 DHF is a small molecular TrkB agonist that can easily cross the blood-brain barrier. It can increase brain-derived neurotrophic factor (BDNF), a protein that improves neuroplasticity, learning, and memory. BDNF deficiencies are connected to numerous cognitive ailments as well. However, no human studies have been conducted. 26 In mice, 7,8 DHF appears to enhance spatial memory. When converting the effective dose for mice to humans, Thesis’ Clarity offers roughly 6mg more (about 24mg compared to Thesis’ 30mg). 27

Choline is a precursor to acetylcholine, a powerful neurotransmitter in the peripheral, autonomic, and enteric nervous systems. 10 One study on older adult human participants found that taking 187-399mg per day of choline reduced the risk of low cognitive functioning by nearly 50% compared to an intake under 187mg per day. 28 The CDP choline content in Thesis’ Energy is 300mg.

A 2010 clinical study on 485 older adult (over 55 years old) subjects found that 900mg per day of DHA improved memory and learning in those with age-related cognitive decline. 11 And another study in healthy adults 18-90 years old found that 580mg per day helped improve memory. 29 Unfortunately, the amounts used in many studies to improve cognitive function are quite a bit more than the 200mg (which is DHA and L-lysine combined) found in Thesis’ Logic.

Like choline, Alpha-GPC acts as an effective acetylcholine precursor. Studies also show that supplementation with Alpha-GPC can stave off exercise-induced reductions in choline levels. The effective amount used in the mentioned study is 200mg, which is less than half of what you’ll find in Thesis’ Clarity (500mg). 12

In addition to being an effective treatment for neuropathic pain, agmatine appears to have potent effects as an antidepressant. A five-year safety case report study concluded that there are no long-term side effect risks. Thesis’ Creativity only contains 250mg, which is well below the amount tolerated by study participants (2.67g per day). 13

Research into epicatechin indicates that it can enhance cerebral blood flow, delivering more oxygen to the brain to ensure it operates at its highest efficiency. The most effective dose for cognitive benefits appears to be over 50mg per day, and Thesis’ Clarity contains 278mg. 14

Lion's mane has been shown to increase nerve growth factor and promote neurite outgrowth of specific neural cells. It's a safe and reliable neurotrophic, but studies have debunked claims of neuroprotective properties. 15 A very small study of only 41 participants found that 1.8g of Lion’s mane may reduce stress and improve cognitive performance. 30 Thesis’ Clarity contains 500mg of Lion’s mane.

Hyperphenylalaninemia, a severe deficiency in phenylalanine, results in reduced dopamine, serotonin, and noradrenaline levels in the brain. 16 It can also alter cerebral myelin and protein synthesis. Supplementing with phenylalanine may provide neuroprotective benefits.

In a 2020 study, phenylalanine was a large component in a mix of seven amino acids that appeared to improve cognitive, psychological, and social functioning in middle-aged and older adults. Effective doses ranged from 0.85g to 1.7g of phenylalanine. A serving of Thesis’ Motivation contains 500mg, a bit under half of the average amount. 31

Examining the six formulas

Thesis has six nootropic formulas in their lineup (even though you can only choose up to four of them per box). Several other nootropic companies like TruBrain and BrainMD boast targeted lineups, as well, but Thesis is the Goldilocks of the bunch. Where BrainMD’s hyper-specific formulas rely on perhaps too few ingredients to make them worthwhile, many of TruBrain’s complex blends lack real specificity. With Thesis, you get targeted effects from numerous ingredients in moderately complex and reasonably priced combinations.

Each Thesis formula has a blend of ingredients that addresses specific needs. Their names give you a pretty big clue as to what the company intends each to do, but a closer look at their ingredients will help you understand how they achieve this.

Their formulas are:

Interestingly, the company thinks of its formulas as working well in pairs. You don't have to utilize them as such, but it's helpful to know how they view their most effective combinations. The following list details their purported combined benefits.

Enhances focus, eliminates brain fog, and lets thoughts flow naturally

Gets you going, keeps you going, and never crashes

Sparks new ideas, inspires extroversion, and revels in openness

You'll usually only take one formula at a time, but these pairs may act synergistically for specific personality types or cognitive needs.

Note that your first shipment of Thesis will contain six individually packed doses for four of these six formulas. Thesis chooses these formulas for you based on the results of an intake questionnaire, but you can make adjustments to that shipment on the customer dashboard before the shipment leaves their warehouse.

Let's take a closer look at each formula as they would appear with caffeine included.

Thesis Clarity

Thesis Clarity relies on 7,8 DHF (dihydroxyflavone), Alpha GPC (glycerylphosphorylcholine), epicatechin, and lion's mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention. It's particularly adept at cutting through brain fog.

Here's a look at Clarity's full ingredients list:

  • Alpha GPC: 500mg
  • Lion's Mane Mushroom: 500mg
  • Camellia sinensis tea leaf: 278mg
  • Dihydroxyflavone: 30mg
  • Caffeine: 100mg
  • L-Theanine: 200mg

One dose of Clarity consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Logic

Thesis Logic contains triacetyluridine (TAU), which caters to the health of the entire central nervous system. It also uses phosphatidylserine to help facilitate communication between and protection of brain cells. 17

This is Logic’s complete ingredients list:

  • Ginkgo Biloba: 160mg
  • Theobromine: 100mg
  • Phosphatidylserine: 400mg
  • High DHA Algae: 200mg
  • Triacetyluridine: 30mg
  • Bacopa Monnieri: 320mg

One dose of Logic consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Energy

Thesis Energy uses cysteine and tyrosine alongside caffeine to deliver a steady energy supply. It also includes TeaCrine, a branded form of theacrine, which partners with caffeine to affect adenosine signaling and prevent fatigue.

Here’s a full list of Energy’s ingredients:

  • Citicoline: 300mg
  • Mango leaf: 300mg
  • Theacrine: 100mg
  • N-Acetyl cysteine: 500mg
  • Indian trumpet tree: 100mg
  • N-Acetyl L-tyrosine: 300mg

One dose of Energy consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Motivation

Blood flow and cellular function are at the core of Thesis Motivation . It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Here's Motivation's full ingredients list:

  • L-Phenylalanine: 500mg
  • Methylliberine: 100mg
  • Vitamin B12: 1000mcg
  • Forskolin: 250mg
  • Artichoke: 450mg

One dose of Motivation consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Creativity

Thesis Creativity aims to realign you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT reuptake inhibition.

Here's a look at Creativity’s ingredients list:

  • Alpha GPC: 150mg
  • Agmatine sulfate: 250mg
  • Panax ginseng: 200mg
  • Ashwagandha root: 300mg
  • Sceletium tortuosum : 25mg

One dose of Creativity consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Confidence

Confidence is designed to work hand-in-hand with Creativity, using saffron and DHH-B from magnolia bark to increase dopamine levels and decrease anxiety. One fascinating ingredient in this formula is sage extract, which one 2021 study showed can help with various memory tasks, including name and face recognition. 18 It’s worth noting, though, that this study employed a 600mg dose compared to Thesis’ 333mg dose.

Here is Confidence's complete ingredients list:

  • Saffron: 28mg
  • Magnesium bisglycinate: 500mg
  • Sage: 333mg
  • Magnolia Bark: 10mg
  • Ashwagandha leaf & root: 120mg

One dose of Confidence consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Our Thesis testing results

Our testing team has tried every Thesis formula (with and without caffeine) to determine their short- and long-term efficacy, at least at an anecdotal level. Here’s a quick summary of our experiences:

Clarity provided our testers with a combined sense of focus and mental ease, though we mostly found that it worked best from its second day forward. The very first dose is mildly effective, but it served us better as a loading dose. We had no crash from either caffeinated or uncaffeinated formulas.

Our testers found that Logic provided a similar experience as Clarity, increasing focus and mental acuity, but the caffeinated formula caused a crash in two of our testers. By excluding the caffeine, that crash can be avoided, though that comes at the expense of some efficacy.

We were very curious about how this formula would perform without the caffeine. Our testers had a noticeable increase in energy without jitteriness about one hour after taking Energy. The caffeinated version caused the worst crash of all the formulas, but we were pleased to find that the formula without caffeine still provided noticeable energy increases without a crash.

Our testers are generally a pretty motivated bunch, so we might not have been the best group to evaluate this particular formula. The testers who felt an uptick in a sense of motivation described it more like a feeling of being able to follow through on tasks with less distraction and completion anxiety.

Creativity, like Clarity, seemed to work better for our testers on its second and third days than on its first. Testers generally described a sensation similar to Motivation but without the feeling of being “on rails,” as one tester put it. It seems to allow for more curiosity and exploration, though not necessarily as much follow-through.

This is Thesis’ newest formula, so fewer of our testers have tried it. Among those who have, one tester with a mild case of social anxiety described feeling a bit more relaxed among groups of people. Testers preferred this formula without caffeine.

Thesis pricing, shipping, and returns

Thesis keeps their price structure decidedly simple. This is refreshing, considering the range of nootropics they offer. You don't have to worry about one formula costing you more than another. However, Thesis doesn't make a non-subscription approach economically feasible.

Every Thesis shipment — including the starter pack — consists of four small boxes, each containing six doses of a single formula. That’s 24 doses/month.

Here's how it works:

  • Any one-time purchase of a one-month supply, including the starter kit, costs $119.
  • When you subscribe, that monthly cost is only $79.
  • You can take an extra 10% off your first order with the coupon code INNERBODY

Subscriptions require an account with Thesis, which gives you access to a well-designed customer dashboard. This is where you can easily make formula adjustments, alter your shipping schedule, or cancel your subscription entirely.

Shipping from Thesis is free in the U.S., and the company offers a 30-day money-back guarantee. In our testing experience, we attempted a return on a second shipment into the subscription. While it isn’t the company’s policy to do so, they refunded our money and let us keep the product. This is similar to some other “Keep it” guarantees we’ve seen from competitors, and we appreciated it.

Getting started with Thesis Nootropics

Thesis' website is easy to navigate, but it is inconvenient that you must complete the signup questionnaire before accessing formula-specific pages. There are ways around this — like direct searching or just knowing the formula URLs — but we think reviewing formulas should be a little easier when you first get to the site. And you won’t be able to place an order for anything until you complete the questionnaire.

The user interface for managing your subscription is exceptionally intuitive. You can quickly adjust your formula combinations, specifying whether or not you want specific formulas to contain caffeine.

Setting up a subscription with Thesis is a straightforward process. Here are the basic steps:

  • Take the Thesis quiz . This will create a starter kit specific to your results. (You can also build a box from scratch if you know which formulas you want to try.)
  • Order your starter kit. We recommend going with the kit Thesis creates after your quiz, but if you change your mind, you can use the customer portal after placing your order to make any changes to the formula combination before it ships.
  • Set up a coaching consultation. This is an optional step, but we recommend it and encourage you to have your first consultation before your kit arrives.
  • Take your nootropics as needed. Most people can experience some of Thesis nootropics' benefits within a few hours of ingestion. Some ingredients and formulas may take a few days to produce results.
  • Refine your order. As you near the end of your first month, you can head over to the Thesis website and customize your next order to include the formula or formulas you like most.
  • Set up follow-up consultations as needed. These will help you refine your future orders and maximize your results.

When you subscribe to the starter kit, you will continue receiving that kit every month until you customize your order. Thesis divides their boxes into four six-dose supplies, and you can mix and match those supplies to suit your needs. For example, you could boost energy on the weekdays and creativity on the weekends by getting a one-month supply with 18 servings of Energy in three packages and six servings of Creativity in a single package.

Personalized insights and coaching

When you take the quiz on the Thesis website, you'll get personalized insights comparing your results to other quiz-takers and a data set developed from nearly 500 scientific studies. The parameters in your results cover don’t completely line up with their formulas, but they include:

These results inform the system to make recommendations for your starter kit. After you order, you can set up a consultation with a Thesis coach. These consultations are free, and you can have as many follow-up sessions as you like. Other companies have apps or online resources like blogs or courses to help you on your nootropic journey, but Thesis’ personalized coaching offers a unique approach and execution.

Consultation calls last around 15 minutes, though some of our testers had their sessions go longer as their coaches' schedules allowed. We received best practices information about taking nootropics that covered dose timing, formula application, and more. Some of our testers also received diet and exercise advice that coincided with their formulas.

Alternatives to Thesis

There are generally two tiers of products in the nootropics landscape. The lower tier consists of products that cost between $20 and $40. Many of these nootropics contain proprietary blends that obscure the exact quantities of ingredients, presumably so companies can use more of the least expensive components. Some companies in this tier disclose their ingredient quantities but may not source them from the highest quality suppliers or perform third-party testing of any kind.

Top brands in this tier include:

  • Onnit Alpha BRAIN
  • Moon Juice Brain Dust
  • Focus Factor

The second tier — where you'll find Thesis — consists of more expensive nootropics that spell their contents out clearly, use high-quality ingredients, and often perform third-party testing to ensure safety and potency. Top brands in this tier include:

  • Qualia Mind

Hunter Focus

We have a comprehensive breakdown of our top nootropics , but here's a concise breakdown of Thesis' most comparable competition.

TruBrain offers one of the widest varieties of nootropics of any company — one of the few catalogs that rivals the variety Thesis offers. They also have some novel and beneficial delivery methods for their nootropic ingredients. Those include energy bars and liquid shots that are outstanding for anyone with difficulty swallowing pills.

TruBrain offers their nootropics in a targeted fashion, not unlike what you get from Thesis. They formerly offered their targeted blends in shot form only, but now you can get any of these targeted blends in capsule or liquid shot form. The shots come in small 1oz pouches that make them easy to take anywhere.

TruBrain's targeted blends include:

This is TruBrain's original blend. It contains seven nootropics, including Noopept, a branded form of N-phenylacetyl-L-prolylglycine ethyl ester. This blend is caffeine-free.

The Strong blend is identical to the Medium formulation in contents and doses, but it also contains 100mg of caffeine.

The Extra Strong formula builds on the Strong blend by adding 150mg of adrafinil (2-(diphenylmethyl)sulfinyl-N-hydroxyacetamide). 21 This wakefulness-promoting substance may also help with weight loss and athletic performance.

TruBrain's Sleep formula contains just four nootropic ingredients: GABA, melatonin, 5-HTP, and a blend that TruBrain calls "functional oils."

Mellow is identical to the medium strength formula, but it adds the functional oil combination used in Sleep.

This formula contains Lion's mane, a mushroom that may promote neural growth , though human studies are necessary to determine if this is true. 22 Its other nootropic ingredients are rhodiola, guayusa, and rosehips.

A 30-day supply of TruBrain nootropic shots costs $89. That's $10 more than the subscription cost for a one-month supply of Thesis. Some of their shots contain caffeine, and others don't. If it already contains caffeine, there's no way to alter a TruBrain formula to be stimulant-free.

The first month of TruBrain capsules costs a bit less, coming in at $69. After your first month, however, the price goes up to $119. That makes Thesis the better value, but if you want the best possible nootropics for sleep support, it might be worth the extra money to check out TruBrain.

Qualia Mind is a brand under the Neurohacker Collective, a company that offers several products to address things like sleep quality, skin health, and vision. They have three nootropics available:

  • Qualia Mind Caffeine-Free
  • Qualia Mind Focus

Their original blend is comprehensive, consisting of nearly 30 ingredients in high doses. That means it's liable to provide you with noticeable effects. It also means you might not know which of those effects are coming from which ingredients, and some of the less beneficial components in your body may also have side effects you'd rather avoid.

The caffeine-free version is identical to the original formula but leaves the caffeine out. Qualia Focus is a more streamlined offering with only seven nootropic ingredients, including caffeine, L-theanine, and L-ornithine. 23

Initial shipments from Qualia Mind are significantly discounted, but after the first month, the price makes theirs one of the most expensive nootropics we've tested. For example, the first month of a subscription to Qualia Mind costs just $39. After that, it costs $139/month. And a one-time purchase is $159.

One inconvenient aspect of Qualia Mind is that a single dose consists of seven capsules, which can get tiresome even for people who don't have trouble swallowing pills. On the bright side, Qualia's 100-day money-back guarantee allows you to try it for a little over three months to determine if you can handle that kind of daily dosing.

Hunter Focus is one of three supplements in the Hunter stack alongside the company's Test and Burn supplements. The stack is intended for male use — Test is a testosterone supplement — but Focus and Burn are suitable for men and women.

Like Qualia Mind, Focus has a long list of ingredients in generous doses. In fact, one serving of Hunter Focus is like taking all six of Thesis' formulas at once. That said, the serving itself is difficult to swallow, as it consists of six large pills.

Another knock on Hunter is that they don't offer a subscription system. That means you can't get an extra discount, and you must remember to reorder when you're running low (theoretically, a nootropic like this should boost your memory). There's also no money-back guarantee to speak of, only a return policy with a relatively short window that only applies to unopened products.

One bottle of Hunter Focus costs $90, and shipping is $8.95 unless you buy more than one bottle at a time. The company will throw a fourth in for free if you buy three bottles at once. That's the only way to get any savings through Hunter.

Individual nootropic components

Many companies offer combinations of nootropic ingredients to perform specific brain-related tasks or even provide globally positive cognitive benefits. However, the scientific research behind most of these ingredients almost always includes just one rather than a combination. Some people prefer to try one at a time to minimize the potential for side effects and determine if one particular ingredient works for them. A few companies offer single-ingredient nootropic supplements for this specific purpose.

Our favorite company dealing in individual nootropic components is Nootropics Depot. They offer a wide variety of single-ingredient supplements and a few targeted blends. The prices are generally fair, with an average range running from $16-$70. A 30-day money-back guarantee covers every purchase, and you get free shipping on orders over $50.

Nootropics FAQ

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Specific nootropics affect different parts of the brain in their own ways. Some — like caffeine — reduce fatigue by blocking adenosine receptors, while others act to protect neural connections that are already present while possibly contributing to new neural growth. 24 Some also mitigate depression and anxiety, which frees up the brain to perform at its best.

Are nootropics safe?

The safety of a nootropic depends on the specific ingredients involved. Many are perfectly safe in the doses commonly employed by nootropic companies, but some can cause reactions like increased heart rate, gastrointestinal discomfort, headache, and even tremors. The smartest thing to do is to talk to your doctor before introducing any new supplement to your regimen.

Do nootropics really work?

Many nootropic supplements are noticeably effective — caffeine is a great example. Efficacy varies depending on the specific component or combination. Fortunately, a lot of companies offer money-back guarantees, so you can try their products to see if they work for you without much financial risk.

Will nootropics make me smarter?

Nootropics won't necessarily make you smarter, but many can increase your alertness, improve short-term recall, and promote neural growth and protection. That creates a great environment for learning if you apply yourself while using nootropics, and many ingredients can help you with the motivation it takes to do so.

How do you pronounce nootropics?

The 'noo' in nootropics comes from the Greek nous , which philosophers use to mean mind or intelligence. The 'tropic' in nootropic comes from the Greek tropikos , which relates to turning or changing. So, nootropic roughly translates to mind-changing. You pronounce the 'noo' like 'new' and the 'tropic' with a long O sound, like 'toe pick.'

Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Mayo Clinic. (2022). Memory lapses: Normal aging or something more? Mayo Clinic Press.

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Kumar, N., Abichandani, L. G., Thawani, V., Gharpure, K. J., Naidu, U. R., & Ramana, G. V. (2015). Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial . Evidence-based Complementary and Alternative Medicine: eCAM, 2016 .

Colucci, L., Bosco, M., Ziello, A. R., Rea, R., Amenta, F., & Fasanaro, A. M. (2012). Effectiveness of nootropic drugs with cholinergic activity in treatment of cognitive deficit: A review . Journal of Experimental Pharmacology, 4 , 163-172.

Yurko-Mauro, K., McCarthy, D., Rom, D., Nelson, E. B., Ryan, A. S., Blackwell, A., Salem, N., Jr, Stedman, M., & MIDAS Investigators (2010). Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 6 (6), 456–464.

Parker, A. G., Byars, A., Purpura, M., & Jäger, R. (2015). The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility . Journal of the International Society of Sports Nutrition, 12 (Suppl 1), P41.

Gilad, G. M., & Gilad, V. H. (2014). Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report . Journal of Medicinal Food, 17 (11), 1256–1259.

Haskell-Ramsay, C. F., Schmitt, J., & Actis-Goretta, L. (2018). The Impact of Epicatechin on Human Cognition: The Role of Cerebral Blood Flow . Nutrients, 10 (8).

Lai, P. L., Naidu, M., Sabaratnam, V., Wong, K. H., David, R. P., Kuppusamy, U. R., Abdullah, N., & Malek, S. N. (2013). Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia . International Journal of Medicinal Mushrooms, 15 (6), 539–554.

Ashe, K., Kelso, W., Farrand, S., Panetta, J., Fazio, T., De Jong, G., & Walterfang, M. (2019). Psychiatric and Cognitive Aspects of Phenylketonuria: The Limitations of Diet and Promise of New Treatments . Frontiers in Psychiatry, 10 , 434708.

Dobolyi, A., Juhász, G., Kovács, Z., & Kardos, J. (2011). Uridine function in the central nervous system . Current Topics in Medicinal Chemistry, 11 (8), 1058–1067.

Wightman, E. L., Jackson, P. A., Spittlehouse, B., Heffernan, T., Guillemet, D., & Kennedy, D. O. (2021). The Acute and Chronic Cognitive Effects of a Sage Extract: A Randomized, Placebo Controlled Study in Healthy Humans . Nutrients, 13 (1), 218.

Cappelletti, S., Daria, P., Sani, G., & Aromatario, M. (2015). Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug? Current Neuropharmacology, 13 (1), 71-88.

Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M., & Kunugi, H. (2019). Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial . Nutrients, 11 (10), 2362.

Lowe, D.W., Dobson, E., Jewett, A.G., Whisler, E.E. (2021). Adrafinil: Psychostimulant and Purported Nootropic? The American Journal of Psychiatry Residents’ Journal, 17 (1).

Sabaratnam, V., Kah-Hui, W., Naidu, M., & David, P. R. (2013). Neuronal Health – Can Culinary and Medicinal Mushrooms Help? Journal of Traditional and Complementary Medicine, 3 (1), 62-68.

Miyake, M., Kirisako, T., Kokubo, T., Miura, Y., Morishita, K., Okamura, H., & Tsuda, A. (2014). Randomised controlled trial of the effects of L-ornithine on stress markers and sleep quality in healthy workers . Nutrition Journal, 13 , 53.

P., E., Rábano, A., Cafini, F., & Ávila, J. (2019). Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease . Nature Medicine, 25 (4), 554-560.

Rauf, A., Olatunde, A., Imran, M., Alhumaydhi, F. A., Aljohani, A. S., Khan, S. A., Uddin, M. S., Mitra, S., Emran, T. B., Khayrullin, M., Rebezov, M., Kamal, M. A., & Shariati, M. A. (2021). Honokiol: A review of its pharmacological potential and therapeutic insights . Phytomedicine, 90 , 153647.

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Lazari, A., Tisca, C., Tachrount, M., B., A., Miller, K. L., & Lerch, J. P. (2023). 7,8-dihydroxyflavone enhances long-term spatial memory and alters brain volume in wildtype mice . Frontiers in Systems Neuroscience, 17 , 1134594.

Liu, L., Qiao, S., Zhuang, L., Xu, S., Chen, L., Lai, Q., & Wang, W. (2021). Choline Intake Correlates with Cognitive Performance among Elder Adults in the United States . Behavioural Neurology, 2021 .

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Docherty, S., Doughty, F. L., & Smith, E. F. (2023). The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study . Nutrients, 15 (22).

Suzuki, H., Yamashiro, D., Ogawa, S., Kobayashi, M., Cho, D., Iizuka, A., Takada, M., Isokawa, M., Nagao, K., & Fujiwara, Y. (2020). Intake of Seven Essential Amino Acids Improves Cognitive Function and Psychological and Social Function in Middle-Aged and Older Adults: A Double-Blind, Randomized, Placebo-Controlled Trial . Frontiers in Nutrition, 7 , 586166.

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Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. Health and wellness celebrities have pushed it, causing a wave of popularity.

Do Thesis nootropics live up to the hype?

  • Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
  • Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
  • Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
  • Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
  • Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
  • Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.

NooCube Nootropic

Quick Verdict

Thesis has a range of suitable nootropic blends to cater to many needs.

However, our #1 nootropic of choice is NooCube. It’s designed for long-term brain changes, not just short-term boosts in mental performance.

What Is Thesis Nootropics?

Thesis Nootropics is a company that specializes in customized cognitive performance products. Dan Freed founded it in 2017.

Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.

This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.

The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.

Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.

The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.

Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

Thesis Nootropics

Customized Blends For Cognitive Enhancement

Take the quiz and see which blends are right for you.

Thesis Nootropics

Thesis Nootropic Ingredients

Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.

The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .

The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.

Thesis Clarity Blend

Alpha gpc (speculative).

Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .

Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .

It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .

It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .

Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.

Lions Mane Mushroom (Speculative)

The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .

According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .

It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .

Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .

While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.

Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.

Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:

Camellia Sinensis Tea Leaf (Speculative)

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.

Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.

Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .

The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.

I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.

Dihydroxyflavone

Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).

BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .

It enhanced memory formation in healthy rats and improved spatial memory in Alzheimer’s disease mouse models [14] .

Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .

This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.

Thesis Energy Blend Ingredients

Citicoline is commonly mentioned in relation to memory enhancement. Studies have shown that 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .

According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .

The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.

Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.

Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .

In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .

These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .

Thesis Energy contains 300 mg of mango leaf.

Theacrine is a purine alkaloid similar to caffeine. It is found in the Camellia kucha plant and is often included in dietary supplements.

Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .

Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .

It may enhance cognitive function and physical performance, either alone or in combination with caffeine [23] .

Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Theacrine manufacturers fund some of these studies.

Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.

N-Acetyl Cysteine

N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.

Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .

Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .

To confirm its benefits, the effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies [27] .

N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.

In human trials, a 600 – 2000 mg dose seems needed for cognitive benefits. Thesis Energy contains 500 mg, which is potentially underdosed.

Indian Trumpet Tree

Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .

Compared to a placebo, this supplementation improved episodic memory and numeric working memory. It also accelerated learning in location tasks.

However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.

The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.

Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.

This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.

L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .

It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.

While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.

It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .

According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.

Thesis Creativity Blend Ingredients

Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.

Agmatine Sulfate

Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.

Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .

It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.

In animal studies, agmatine sulfate has been shown to be safe and well-tolerated, with oral administration effectively increasing its levels in the brain [32] .

This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.

Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.

Panax Ginseng

Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .

It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .

Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .

Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.

Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.

Ashwagandha Root

Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .

It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .

Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .

It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.

Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.

Sceletium Tortuosum

Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .

Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .

Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .

The plant’s bioactive alkaloids are also being explored for commercial medicinal use.

The 25 mg dose in Thesis Creativity is the same as used within the human trials.

Thesis Motivation Blend Ingredients

L-phenylalanine.

L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.

Studies have shown that doses of up to 1200 mg show initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance develops over 2-4 months [44] .

In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .

However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .

Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.

Methylliberine

Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.

Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .

These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .

However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.

The 100 mg dose in Thesis Motivation aligns with the current research.

Vitamin B12 (Speculative)

Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .

There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .

B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.

Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.

Forskolin (Speculative)

Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.

Studies have shown that it restores nest-building and social behaviors in mice with Alzheimer’ s-like symptoms, reduces amyloid plaque deposition, and regulates brain inflammation [53] .

Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .

Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .

These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.

I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.

Artichoke (Speculative)

Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .

In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .

Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .

The 450 mg dose is well under the dose used in these studies.

Thesis Confidence Blend Ingredients

Saffron (speculative).

Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .

Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .

However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.

All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.

Magnesium Bisglycinate

Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .

However, its role in anxiety and mood disorders is less clear [62] .

Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .

Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .

500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.

Sage (Speculative)

Sage, also known as Salvia, has traditionally been known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .

This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.

However, this has not been replicated.

While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.

Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.

Sceletium Tortuosum (Speculative)

As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. The same 25 mg dose is used in human trials.

Magnolia Bark (Speculative)

Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.

Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .

The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.

Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .

These are rodent studies, so they cannot be extrapolated to humans. Regardless, they are included based on the mechanistic data and the theory that the 10 mg dose does the same thing in humans.

Ashwagandha Leaf & Root

The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.

Thesis Logic Blend Ingredients

Ginko biloba.

Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.

Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .

Clinical trials have shown it to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .

Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.

Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.

Theobromine

Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.

Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .

Further studies are needed to fully understand its impact on cognition.

Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .

However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .

More research is required to confirm theobromine’s cognitive and mood-related effects.

Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.

Phosphatidylserine

Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .

Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .

It is well absorbed in humans and crosses the blood-brain barrier.

Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated. Dosages ranging from 100 to 800 mg per day are advised for cognitive support [76] [77] .

Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.

High DHA Algae

DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.

DHA consumption improves adult cognitive abilities, especially when paired with eicosapentaenoic acid (EPA) [78] .

This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.

Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.

Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.

Triacetyluridine (Speculative)

Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .

The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).

Results indicated significant early improvement in depression symptoms.

Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.

Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.

Bacopa Monnieri

Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.

Studies have demonstrated that bacopa extract, specifically bacosides A and B, increases memory formation, recall, and cognitive function [80] .

It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.

Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.

Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . However, more research is needed to thoroughly grasp its usefulness across many cognitive domains.

Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.

Thesis Nootropics Price

Thesis Nootropic Review

Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:

  • Subscription = $79
  • One Time Purchase = $119

This is regardless of whether you purchase a personalized starter kit or build your own box.

You can’t buy them individually, either. You must purchase four boxes. When building your own, you can choose whether you want four of the same blend or mix and match.

They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.

Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.

Is Thesis Nootropics Really Personalized?

I went through the initial quiz to see how they “personalize” their nootropic stack.

Thesis Baseline

Here is what they recommended me:

Thesis Picks

Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.

However, the fact they have multiple blends means people can experiment to find which works best for them.

I will say, though, that if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, and many are underdosed.

Benefits Of Thesis Nootropics

Multiple blends for different purposes.

To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.

Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.

Options For Stimulants Or Not

You can choose whether or not to include stimulants in your Thesis Blends. If you add the caffeine and L-theanine nootropic stack, the most potent synergistic brain booster, every blend will provide similar benefits.

However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.

My Experience With Thesis

Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.

I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.

The Logic and Clarity Blends had small positive effects on my concentration on mentally demanding tasks like writing, coaching, or podcasting.

If I were to continue taking Thesis, I’d opt for either of these two blends.

Who Is Thesis For?

Busy working professionals.

Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.

They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.

Creative Artists

For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can help break through creative blocks, foster innovative thinking, and maintain a heightened state of inspiration.

They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.

Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.

The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.

Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.

They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.

Coffee Haters

Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.

These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.

User Testimonials And Reviews

You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)

I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.

Thesis Side Effects

Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.

Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

Thesis Alternatives

If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.

Nooceptin Nootropic

SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.

It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.

This brain supplement contains Lion’s Mane Extract, Citicoline, rhodiola rosea extract, L-theanine, Bacopa Monnieri, ginkgo biloba, and panax ginseng.

Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.

Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.

Read more in our Nooceptin review .

Mind Lab Pro

Mind Lab Pro

Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.

Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.

Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.

These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.

Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.

Our Mind Lab Pro review goes into great detail.

Braini

Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.

Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.

Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.

Our Braini review contains an in-depth breakdown.

Vyvamind

Vyvamind is a nootropic supplement containing caffeine and L-theanine. It helps users focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.

This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.

Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.

Our Vyvamind review goes into great detail.

NooCube

Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. It contains ingredients such as Bacopa Monnieri, L-tyrosine, and L-theanine.

These are well-known for their mental health advantages. However, several compounds, such as Huterzine-a and Alpha GPC, remain speculative without additional investigation.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.

Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.

Our detailed analysis can be found in our NooCube review .

Frequently Asked Questions

What is thesis nootropic and what does it do.

Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Depending on the blend chosen, users can expect improvements in focus, reduction in procrastination, stress management, and memory recall.

Does Thesis Work Like Adderall?

Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.

Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.

I’ve explored the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.

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  • Tildesley, N. T., Kennedy, D. O., Perry, E. K., Ballard, C. G., Savelev, S. A. W. K., Wesnes, K. A., & Scholey, A. B. (2003). Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacology Biochemistry and Behavior, 75(3), 669-674.
  • Lee, H. K., & Lee, U. J. (2015). Effects of Ethanol Extract from Magnolia Officinalis on Anxiety and Cognitive Function. The Journal of Internal Korean Medicine, 36(4), 507-517.
  • Borgonetti, V., Governa, P., Manetti, F., Miraldi, E., Biagi, M., & Galeotti, N. (2021). A honokiol-enriched Magnolia officinalis Rehder & EH Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. Journal of Pharmacy and Pharmacology, 73(9), 1161-1168.
  • Kim, M. S., Bang, J. H., Lee, J., Han, J. S., Baik, T. G., & Jeon, W. K. (2016). Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system. Phytomedicine, 23(12), 1356-1364.
  • Stough, C., Clarke, J., Lloyd, J., & Nathan, P. J. (2001). Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. International Journal of Neuropsychopharmacology, 4(2), 131-134.
  • Canter, P. H., & Ernst, E. (2007). Ginkgo biloba is not a smart drug: an updated systematic review of randomised clinical trials testing the nootropic effects of G. biloba extracts in healthy people. Human Psychopharmacology: Clinical and Experimental, 22(5), 265-278.
  • Cova, I., Leta, V., Mariani, C., Pantoni, L., & Pomati, S. (2019). Exploring cocoa properties: is theobromine a cognitive modulator?. Psychopharmacology, 236, 561-572.
  • Judelson, D. A., Preston, A. G., Miller, D. L., Muñoz, C. X., Kellogg, M. D., & Lieberman, H. R. (2013). Effects of theobromine and caffeine on mood and vigilance. Journal of clinical psychopharmacology, 33(4), 499-506.
  • Mitchell, E. S., Slettenaar, M., Vd Meer, N., Transler, C., Jans, L., Quadt, F., & Berry, M. (2011). Differential contributions of theobromine and caffeine on mood, psychomotor performance and blood pressure. Physiology & behavior, 104(5), 816-822.
  • Glade, M. J., & Smith, K. (2015). Phosphatidylserine and the human brain. Nutrition, 31(6), 781-786.
  • Cenacchi, T., Bertoldin, T., Farina, C., Fiori, M. G., Crepaldi, G., Azzini, C. F., … & Allegro, L. (1993). Cognitive decline in the elderly: a double-blind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration. Aging Clinical and Experimental Research, 5, 123-133.
  • Kang, E. Y., Cui, F., Kim, H. K., Nawaz, H., Kang, S., Kim, H., … & Go, G. W. (2022). Effect of phosphatidylserine on cognitive function in the elderly: A systematic review and meta-analysis. ????????, 54(1), 52-58.
  • Ma, X., Li, X., Wang, W., Zhang, M., Yang, B., & Miao, Z. (2022). Phosphatidylserine, inflammation, and central nervous system diseases. Frontiers in Aging Neuroscience, 14, 975176.
  • Yurko-Mauro, K., Alexander, D. D., & Van Elswyk, M. E. (2015). Docosahexaenoic acid and adult memory: a systematic review and meta-analysis. PloS one, 10(3), e0120391.
  • Jensen, J. E., Daniels, M., Haws, C., Bolo, N. R., Lyoo, I. K., Yoon, S. J., … & Renshaw, P. F. (2008). Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients. Experimental and Clinical Psychopharmacology, 16(3), 199.
  • Singh, H. K., & Dhawan, B. N. (1997). NEUROPSYCHOPHARMACOLOGICAL EFFECTS OF THE AYURVEDIC NOOTROPlC BACOPA MONNlERA LINN.(BRAHMI). Indian Journal of Pharmacology, 29(5), 359-365.
  • Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008). Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. The journal of alternative and complementary medicine, 14(6), 707-713.
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Thesis Nootropics Review 2024: Honest Thoughts + Am I Still Buying?

  • Last updated: August 28, 2024

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About Dr. Steve Kim, MD

Physician Advisor

does thesis pills work

After using Thesis nootropics for more than a year, for me, the higher price point is definitely worth it for the cognitive benefits I’ve experienced. Specifically, I’ve noticed that I am not feeling overwhelmed as often as I was prior, and I am able to focus and complete tasks with more ease.

Thesis Overview

  • Price:  $119 for one-time purchase or $79 with subscription
  • Helps With:  Cognitive function, including motivation, memory, focus, and more
  • Side Effects:  Headache, stomachache, and more
  • Safety: Made with ingredients that are Generally Recognized As Safe (GRAS) by the FDA or have passed Phase III clinical trials
  • Dietary Information:  Vegan, and made without gluten, eggs, and nuts

Thesis Nootropics

Thesis offers a variety of  nootropics, also called “smart drugs,” which are medicinal substances that improve cognitive function, specifically memory, thinking, and learning. While some prescription nootropics are FDA-approved, Thesis is not regulated by the FDA and is available over-the-counter (OTC). However, their ingredients are third-party tested and they only use ingredients that are either Generally Recognized As Safe (GRAS) by the FDA or have passed through Phase III clinical trials. 

I’ve been taking Thesis for over a year now, about six times a week, and I’ve noticed some significant improvements in terms of how often I feel overwhelmed, as well as my ability to focus and stay on task. While I know Thesis won’t work well for everyone, these nootropics agree well with me and I’ll continue using them to help boost my productivity, focus, and more. 

In this article, I’ll delve into my experience using Thesis nootropics, as well as discuss their potential benefits, side effects, and more.

Thesis Nootropics

  • Custom blends
  • Personal coaching / support by nootropic experts
  • No proprietary blends (AKA no hidden ingredients!)
  • Caffeinated or noncaffeinated formulas
  • Effective ingredients
  • No free trials
  • Relatively high monthly cost

My Experience Taking Thesis Nootropics

I’ve been loving Thesis since I started using their products, specifically the Clarity, Creativity, Logic, and Energy blends, over a year ago. While there’s no nootropic that’ll offer you the same potency you’d get from Adderall, or other prescription stimulant medications, I’ve found Thesis to work surprisingly well for my needs.

When using them 6 times a week, they have offered notable improvements in how well I’m able to focus and stay on task. In practice, this usually looks like a clearer mind and an improved ability to maintain a relaxed state of mind while completing various tasks. As someone who feels overwhelmed fairly often, this is a welcomed change of pace.

With their Clarity and Creativity blends, in particular, I just feel leveled out. I’m able to sit down and work, without feeling like I’m just hopped up on too much caffeine, a feeling that really makes me uncomfortable. 

In the world of nootropics, where certain products don’t seem noticeable whatsoever, it cannot be overstated just how awesome my experience with Thesis has been.

Benefits of Thesis

As a customer, you’ll have the opportunity to speak with their coaches at any time. I have reached out on a few occasions, just to talk about the fascinating world of nootropics. In particular, I have had amazing conversations with one of their neurologists, Cindy. It truly is nice to speak with other individuals who are as fascinated with the science behind nootropics as I am.

Another aspect of Thesis that I really respect is that they clearly publish not only which ingredients they include, but also the exact amounts of each ingredient. This matters because it allows consumers to actually cross-check the research behind the ingredients/dosages, an unfortunate rarity in the supplement space.

Thesis nootropics product

  •  6 custom blends, each with unique effects that may work well for many individuals
  • Personal coaching/support from nootropic experts
  • No proprietary blends (hidden ingredients)
  • Caffeinated or non-caffeinated formulas
  • Effective ingredients that are backed by science and are third-party tested
  • Available OTC
  • Not FDA-approved
  • Relatively high monthly price, which may not work for everyone

How Does Thesis Work?

You’ll start by filling out a questionnaire on their website, which should only take a few minutes. Once you’re done with the survey, Thesis’ algorithm will run through its millions of data points to predict which of their blends may work best for you. 

Once you place your order, either as a one-time purchase or as a subscription, you’ll be shipped your blends.

Per the instructions, you’ll begin taking your blends and note how you feel in the included daily journal. This will help your track whether your blends are the right fit for your needs or if they need to be adjusted. You’ll also be able to speak with one of their coaches at any time for additional support. 

Related reading: Stasis Supplement Review – Our Research, Testing, and Impressions

Thesis vs. Alternatives

 We’ve created this comparison table to pit Thesis up against Onnit and Mind Lab Pro , two other popular nootropic brands.

Thesis Nootropics Side Effects

The ingredients in Thesis may lead to side effects in some individuals, including: 

  • Stomachache
  • Signs of an allergic reaction

If you experience any prolonged discomfort, stop taking Thesis and reach out to your healthcare provider. Seek urgent medical care if you experience serious symptoms of an allergic reaction.

The Verdict: Are Thesis Nootropics Worth It?

Thesis offers a complete toolkit of nootropics that are tailored to your needs, in addition to ongoing expert support. Unlike other nootropics, which may include unnecessary or hidden ingredients, Thesis only offers what you need with their six unique blends that focus on supporting logic, energy, creativity, clarity, motivation, and confidence. Once you find the blend or blends that work for you, you can opt into a subscription and save on costs. 

While the monthly cost may be on the higher side, the ability to select only the blends you need, instead of opting for a nootropic that may include ingredients that are unnecessary for your particular needs, is definitely a major benefit of opting for this provider over others.

Keep in mind that Thesis will not feel as potent as prescription stimulant medication and that certain blends may lead to side effects, like gastrointestinal problems or headaches, in some. It’s always best to speak with your healthcare provider prior to trying Thesis to ensure that it is safe for you to do so.

Thesis will not be as potent as Adderall, a prescription medication. However,  Thesis , a type of nootropic or “smart drug,” may work well for some individuals in boosting cognitive function, focus, and more. 

Some nootropics can be used every day. However, it’s best to follow the specific’s products instructions, as well as speak to your healthcare provider about safe use.

Thesis  may be safe for some individuals to use. According to the company, they only use ingredients that are either classified as Generally Recognized As Safe (GRAS) by the FDA or that havve passed through Phase III clinical trials. However, it’s always best to speak with your healthcare provider prior to trying Thesis to ensure that it is safe for you to use.

Thesis does not offer free samples, however, they do offer a no-questions-asked refund. 

Thesis offer caffeinated and caffeine-free formulas.

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How can we help?

Month 1: what to expect, month 2+: what's next, quality control & manufacturing, subscriptions & shipping + orders, health & safety.

What are nootropics, and how do they work?

Nootropics are a class of compounds that enhance cognitive function by helping to promote neurotransmitter activity to support motivation, mood, memory, and focus. Some of the most widely consumed nootropics are caffeine and L-theanine, found in coffee and tea. Whether you’re looking to enhance your productivity, maintain mental sharpness, or improve working memory, nootropics can offer a range of benefits to support your cognitive goals.

How do we recommend nootropics?

We developed six unique nootropic blends designed to cater to different cognitive goals. Our quiz assesses various traits to pinpoint areas with the greatest potential for improvement (e.g., focus, energy, motivation, etc.). Based on your quiz results, we make recommendations to match you with the four blends we think you’ll experience the most benefits from. The Starter Kit contains four blends, designed for you to try a new blend each week, moving you closer to the blend that best complements your personal brain and goals.

Can I select my blends instead of getting a Starter Kit?

Yes. If you have a clear idea of which blend(s) you want to try, you can customize your next refill on the Build Your Box page. If you already took the quiz and want to adjust your blends but the order has already been processed, contact us right away at 646-647-3599 or email us at [email protected] so we can help.

Do you offer caffeine-free blends?

Yes! You can choose to receive a caffeine-free version by selecting the Caffeine-free toggle on the Build Your Box page. If you would like to make adjustments to your blends after taking the quiz, please email us at [email protected] so we can update your order to caffeine or caffeine-free. If you’ve already received the caffeinated blends and do not want the caffeine, you can simply remove the white capsule from each packet, which contains all the caffeine content within each blend.

Where can I find more information on each ingredient?

If you want to learn more about the science behind each ingredient, check out the Ingredients page on our website. To discuss the function or science behind our ingredients, speak with any of our Coaches by calling us at 646-647-3599 or emailing us at [email protected].

Can I open the capsules and pour them into water?

You can — but we don’t recommend it. We encapsulate the ingredients because they have a strong, unpleasant taste. If you have a hard time swallowing capsules, it is perfectly safe to mix the contents into a smoothie, juice, or flavored drink to help mask the taste.

I want to try before I buy. Do you offer free samples?

We don’t offer free samples. However, if you aren’t happy with Thesis, we will offer a refund within 30 days of your first delivery.

How does the Starter Kit work?

The Thesis Starter Kit introduces you to four unique blends, each designed to be tested over one week, helping you discover which blend best aligns with your neurochemistry and goals. You can begin your Starter Kit journey with any blend. Start by taking one full packet each morning for six consecutive days, followed by one day off, before moving on to the next blend. It's important to monitor how each blend affects you, tracking changes across traits like memory, alertness, mood, and productivity. At the end of the four weeks, the goal is to identify the one or two blends that benefited you the most. For subscriptions, remember to customize your next box through your Thesis Account before your next shipment. If you opted for a one-time purchase, you can select your preferred blends for your next order by visiting the Build Your Box page.

Should I take Thesis blends with food or on an empty stomach?

We recommend taking Thesis blends on an empty stomach to maximize the effects and absorption of the ingredients. However, if you have a sensitive stomach, your blends can be taken with a meal or light snack to make them more tolerable.

Can I still drink coffee?

Yes. For most Thesis users, you can continue to enjoy coffee even if you’re taking our caffeinated blends. Keep in mind, that our caffeinated blends contain 100 mg of caffeine and 200 mg of L-theanine, which is roughly equivalent to a cup of coffee, so depending on your sensitivity, you may want to monitor your total caffeine intake. Many Thesis users have even reported that their coffee consumption has gone down and become less reliant on coffee to energize them throughout the day. If you’ve received the caffeinated Thesis blends and do not want the additional caffeine, you can simply remove the white capsule from each packet, which contains all caffeine content within each blend.

How long until I start seeing results?

Many Thesis users will begin to notice the initial effects within 60 to 90 minutes after taking it. But depending on your body's metabolism and your familiarity with nootropics, it could take a few days of consistent use for the full effects to ramp up. So, patience is key! For long-term improvements in cognitive performance, consistent use is crucial. Once you've found the blend that best suits your brain chemistry, give it about 4-6 weeks to gauge the true changes and benefits.

Are there any known side effects?

Experiencing side effects like headaches, nausea, anxiety, or agitation can occur. If discomfort arises it's important to listen to your body; this could mean adjusting the dosage, spacing out the intake, or switching to another blend. Identifying what doesn't work is just as important as finding what does. It’s important to remember that everyone responds differently to supplements, so we recommend you discuss any effects you may experience with your doctor. If you would like more information, contact us at 646-647-3599 or email us at [email protected] to speak with one of our Thesis Coaches.

What happens if I don’t like one or more of my blends?

Discovering that a blend isn't right for you is normal and a positive step forward! It's all part of the optimization process to help you pinpoint the nootropic blend(s) that best enhances your cognitive function. If you aren’t noticing any effects from a blend after taking it for six consecutive days, it's a sign to adjust your selection for the next month. If you need more guidance on assessing the effectiveness of each blend, our Thesis Coaches can provide recommendations and tools to make this process easier. Give us a call at 646-647-3599 or send us an email to [email protected].

Do I need to take all of the capsules in a packet?

While the capsules in each packet are based on dosages shown to be effective, we understand that everyone's body reacts differently. The nootropic ingredients are evenly distributed across the brown capsules, allowing you to adjust your dosage by adding or removing these capsules. The white capsule in each packet only contains caffeine and L-theanine, giving you more flexibility on what you need each day. If you’re interested in increasing the dosage beyond the recommended capsules in each packet, please consult with one of our Coaches by calling us at 646-647-3599 or emailing us at [email protected].

I finished my Starter Kit. What do I do now?

Congrats! Finishing your Starter Kit is a significant milestone towards helping to improve your cognitive performance. The next step is selecting the one or two blends that benefited you the most, even if the changes were subtle. Now, you can start fine-tuning your experience, using your blends based on what you need that day (e.g., mental clarity, energy, motivation, and so on). During the second month, continue to pay attention to the changes in your cognitive performance and well-being. Before long, you'll find yourself settling into a rhythm that feels right.

Can I try the blends that were not included in my Starter Kit?

Absolutely! We have six unique nootropic blends, so if you’re interested in trying the remaining blends that weren’t in your Starter Kit, we encourage you to keep experimenting. If you choose to go with a new blend, the same recommendations apply: use the blend for six consecutive days to allow your brain and body to adapt to these new ingredients before determining its effect.

How often should I take my blends?

Thesis is designed for daily use–with intentional rest days built in. Incorporating 1-2 days off per week can prevent building up a tolerance to your blends and allows you to reassess your baseline. If you have a very busy week, you can take your blends all seven days; just adjust for next week by taking two rest days.

What happens if I take more than the recommended dose?

Although our blends were formulated to be taken once daily, we understand some days require extra support. If you need to extend past the typical 4-6 hour half-life, taking a second packet four hours after the first is safe. Of course, everybody responds to supplements differently, so please listen to your body. Please don’t exceed two packets in any 24-hour period. Additionally, be mindful of taking a packet within eight hours of your planned bedtime as disturbing your sleep is counterproductive to your cognitive health.

Can I take more than 1 blend per day?

Yes. While Thesis aims to identify your single optimal blend, we know for some, two blends might be needed to cater to different requirements throughout the day. If you choose to take two blends in a day, we recommend spacing them at least four hours apart to prevent any potential interactions or absorption issues. For advice on combining blends safely and effectively, please speak with one of our Coaches who can help tailor recommendations to your specific needs and goals.

What are the long-term effects?

In clinical trials, none of our ingredients show negative long-term effects. Many nootropics become more effective over time due to the compounding effects on brain health and the structural integrity of neurons. Early research studying the long-term effects of certain nootropics ingredients shows improvement in cognitive traits like memory retention, cognitive flexibility, and focus following persistent use.

Do benefits continue even after I stop taking my blends?

One of the remarkable benefits of nootropics is the neuroprotective effects that promote the long-term health of our brains. For example, by increasing Brain-Derived Neurotrophic Factor (BDNF) in the brain, nootropics promote adaptability to improve traits such as attention, learning, and emotional regulation–when paired with deliberate effort, such as challenging yourself with complex puzzles, practicing a skill, or trying to remember information without looking it up. For a comprehensive overview of our ingredients, their respective benefits, and the latest clinical research, please visit the Ingredients page on our website.

Will I become reliant on taking my blends?

No, you won’t develop a dependency on any of our blends. Because nootropics are non-habit-forming compounds, you have the flexibility to pause or stop taking them without experiencing unwanted side effects.

Where do you source your ingredients from?

Our ingredients are globally sourced to ensure we're using the best available, but all our products are manufactured right here in the U.S. We utilize a combination of natural and synthetic ingredients for consistency and control, like our lab-created caffeine, which reduces batch variability.

How do you test for purity and potency?

To guarantee each blend meets our high standards for purity and potency, we conduct regular third-party lab testing. Unlike many supplement brands, our blends contain minimal fillers and always use the most bioavailable form of active ingredients.

Do you have third-party testing?

We rely on third-party labs for detailed testing to ensure each ingredient and finished product matches our standards for concentration and purity. All of our products go through rigorous quality control testing, as well as batch-specific COAs (Certificate of Analysis) for all raw ingredients and finished goods, emphasizing our commitment to consistency and safety.

What is the shelf-life of your blends and how should they be stored?

Our blends have a two-year shelf life and maintain their efficacy when stored at room temperature.

Are your ingredients allergen-free and/or vegan?

All our ingredients are vegan and free from gluten, eggs, and nuts. While our manufacturing process is designed to minimize any cross-contamination, our facilities process other products, so we cannot offer certified vegan or gluten-free guarantees.

Are your blends FDA-approved?

In accordance with manufacturing practices in the United States, dietary supplements do not go through pre-market FDA approval. Thesis follows current Good Manufacturing Processes (cGMP), which are maintained by the FDA to ensure proper supplement manufacturing. FDA regulates everything from raw material selection to product safety to labeling. All of our ingredients are classified by the FDA as Generally Recognized as Safe (GRAS) or have undergone phase III clinical trials, which both establish measures of safety.

How does my subscription work?

At checkout, you have the option of selecting the subscription model priced at $79 or opting for a one-time purchase for $119. By selecting the subscription option, a new order will be shipped to your address every 28 days unless any adjustments have been made to your subscription in your Thesis Account . You can select or update your blends or reschedule your next order if you're traveling or have simply fallen behind on taking them and have a surplus of packets.

Can I pause my subscription?

We can't pause a subscription in perpetuity, but you can reschedule your next order to any date in the future. You can manage your subscription and delivery schedule by logging into your Thesis Account .

Can I cancel my subscription?

You have full control of your subscription with Thesis and can cancel at any point before your next order has been processed. You can do this by logging into your Thesis Account , selecting "Manage Subscription” in the “My Subscription” tab, and scrolling to the bottom of the page.

Do you offer refunds or returns?

Yes. If you are not 100% satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product, including shipping. Refunds apply to your first order only. For subsequent orders, you may reschedule, skip, or cancel at any time in your Thesis Account . If you have issues with subsequent orders, please contact us at [email protected], let us know what happened and we’ll see what we can do.

What are your shipping delivery times?

Once your order has been placed, our team will work on getting your order ready within 1-2 business days–excluding holidays and weekends. The estimated delivery window is between 3-7 business days. Expedited shipping methods are available for one-time purchases on our website, however, if you’re a Thesis subscriber and would like an expedited shipment, please email us at [email protected] or call 646-647-3599. For all standard and expedited shipping methods, orders placed on Friday after 12 PM ET will be processed on Monday to ship.

How can I track my order?

By logging into your Thesis Account and navigating to the Order History tab, you’ll be able to track your order by clicking on the order number. If you’re experiencing issues finding the tracking information, please contact us at [email protected] with your order number.

Why hasn’t my order tracking updated?

Movement on your tracking link can take up to 24 hours to update. If you continue to see no movement after 24 hours please contact us at [email protected] with your order number and we will look into it further.

Why does the DHL tracking show a different date from USPS tracking?

DHL tracking updates are based on USPS updates. In some cases, the DHL tracking will show a later delivery date initially and then update once USPS has a more accurate estimate. Additionally, DHL hands off the package to USPS in the last leg of delivery, so when this happens your order is often delivered within a couple of days.

Why does my tracking link show it was delivered, but I didn’t receive it?

Please check in and around your mailbox, or check with your neighbors to see if the package was mistakenly delivered to them. If you still can’t locate your package after 48 hours, please contact us at [email protected].

Do you ship internationally?

Due to complexities with various customs regulations, we don’t currently ship internationally. We do, however, ship to all 50 U.S. states and the five major territories (American Samoa, Guam, Northern Mariana Islands, Puerto Rico, and U.S. Virgin Islands).

Can I change my shipping address after placing my order?

We’ll do our best to make any updates to your order before it has left our fulfillment center. The fastest way to contact us is by calling 646-647-3599 between 10 am - 5 pm ET or sending us an email at [email protected], with your order number, original shipping address, and the new address you wish to change to.

Can I take Thesis while on antidepressants, stimulants, and non-stimulant medications?

Psychopharmaceutical medications, including antidepressants, stimulants, and non-stimulants, may interact with ingredients in Thesis, potentially leading to adverse or combinatorial effects. It’s important to speak with your primary medical provider before starting any new supplement or altering any course of medication. They will be able to provide the best advice regarding the safety of adding Thesis to your routine.

Are there any pre-existing conditions that make someone ineligible to take Thesis?

You should consult your primary medical provider before taking Thesis blends, especially if you are pregnant, planning to become pregnant, are breastfeeding, or have a history of any of the following: high blood pressure, heart disease, chest pains, stroke, seizures, high cholesterol, obesity, psychiatric conditions, if you smoke, or have a health problem that could be made worse by a change in diet or supplement routine.

Does Thesis replace my ADHD medication?

Our blends and many stimulant or non-stimulant medications will impact the same neurochemical systems (e.g., dopamine, norepinephrine, and serotonin) involved in mood, attention, energy, and focus. While Thesis may support cognitive function, it is not designed to treat, cure, or replace medication for ADHD or any other medical condition. Discuss with your healthcare provider for guidance tailored to your health needs.

Can I take Thesis if I’m under 18?

Our product is one of the most comprehensive nootropics systems on the market and our ingredients are backed by hundreds of clinical research papers. Unfortunately, the research conducted on these ingredients did not include participants who were under the age of 18. We advise against children taking our product and encourage you to consult a pediatric healthcare provider for advice tailored to minors.

Is it safe to take if I’m pregnant or breastfeeding?

Our product is one of the most comprehensive nootropics systems on the market and our ingredients are backed by hundreds of clinical research papers. Unfortunately, the research conducted on these ingredients did not include participants who were pregnant, nursing, or breastfeeding. For that reason, you should always consult your healthcare provider before starting any new supplement to ensure it is safe for you and your baby.

Can I use my HSA or FSA account to pay for Thesis?

Most FSA and HSA programs will cover the cost of prescription medication; however, since our supplements do not fall into the prescription category, you may not be eligible for reimbursement through your FSA or HSA program. Consult your HSA or FSA plan administrator to confirm which types of supplements, if any, are eligible for reimbursement under your specific plan.

Didn’t find what you were looking for? You can always call or email.

[email protected]

1-646-647-3599

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Nootropic formulas to activate every kind of brain.

Curious About Brain Optimization? Thesis Nootropics May Be Your In

Pills for creativity, energy, confidence, and more.

By Will Price and Rebekah Harding

Medically Reviewed by Sydney Greene, M.S., R.D.

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Ever feel like you have the ability but not the willpower or inspiration to excel at your job? Or maybe you’re stuck in a creative rut and are struggling to get yourself out. Thesis , a nootropics company, wants you to stop being so hard on yourself.

Nootropics are the buzzy brain-boosting substances of the moment, and Thesis attempts to match people to different nootropic blends designed for certain needs—creativity, confidence, energy, clarity, logic, and so on. But can you really summon the powers of creativity on demand from a pill? Myself, and fellow Edge writer Rebekah Harding, tried Thesis for three months to find out. Here’s what you need to know. 

Why You Should Trust Us

Hone Health is a team of health-obsessed journalists, editors, fitness junkies, medical reviewers, and product testers. The two authors of this review, Rebekah Harding and Will Price, spent months taking Thesis’ nootropics blends and logging how we felt. We’ve reported on the ingredients Thesis incorporates in its nootropic blends extensively, such as  ashwagandha ,  Alpha-GPC ,  Lion’s mane , and more.

For this review, we opted to review the product and service independently, as nootropics do not all affect people in the same way. Here’s what we found. 

Thesis Nootropics

Thesis Nootropics

Personalized recommendations.

  • High quality ingredients, third-party tested

Excellent customer service

Not for everybody, what is thesis.

Thesis’s thesis (sorry, I had to) is that you are capable of more. But as co-founder and CEO Dan Freed says on the back of the box the pills come in, “…people thought I was lazy, stupid, or unmotivated. I knew there was more in me.” Freed and his brand propose that the solution to this conundrum many of us face may be nootropics, which are substances that aim to improve cognitive performance. 

New users are funneled through a quiz that determines the best nootropic blends for them—each named for the feeling they’re meant to evoke, e.g. confidence, clarity, creativity. Boxes come with four blends, each of which should last one week, with auto-renewing deliveries shipping at $79 a month. (Note: you can buy Thesis for just one month, but it will cost $119). 

You’re meant to take notes on how each blend makes you feel and, after you’ve completed your first box, adjust which blends you receive going forward.

What are nootropics?

Nootropics are medicinal substances (some pharmaceutical, some natural) that take aim at improving brain performance—memory, creativity, motivation, mood, as well as anxiety reduction and sleep improvement.

While most have heard of popular nootropics like caffeine , creatine , or nicotine , most over-the-counter nootropic supplements—like Thesis—are formulated largely with herbs, vitamins, minerals, and other natural compounds that are known to benefit the brain.

Thesis ingredients

Each Thesis blend contains different ingredients, many of which are supported by solid research. Here are a handful. 

Lion’s mane: Mushrooms that contain hericenones and erinacines, which can stimulate nerve growth and may offer potential cognitive benefits ( 1 ). In addition to thinking capacity, these mushrooms may lower the risk of age-related brain diseases, like Alzheimer’s disease ( 2 ).

Alpha-GPC: May increase your levels of a neurotransmitter called acetylcholine, which facilitates memory and learning, and plays an important role in cognitive function ( 3 ). 

L-Theanine: An amino acid that can positively affect mood. Studies have found L-theanine may be a beneficial nootropic for mood and mental health. It may also help ease anxiety and stress levels ( 4 ).  

Ashwagandha: An ancient herb taken for thousands of years, ashwagandha is an adaptogen that has been found to reduce cortisol —stress—levels in humans, which can have a number of powerful knock-on effects on the brain ( 5 ). 

DHA (Omega-3): This omega-3 fatty acid plays a role in supporting cognitive function and promoting growth and maintenance of brain cells . Research suggests that DHA may improve memory, learning, and overall cognitive performance ( 6 ). 

Synapsa: This patented extract of Water Hyssop boasts nootropic benefits such as enhanced memory and cognitive function ( 7 ). Research shows that taking Synapsa regularly may improve your information processing speed, increase your attention span and enhance your memory ( 8 ).

Ginkgo Biloba: Ginkgo Biloba has antioxidant properties, which are associated with cerebral blood flow and neuroprotection ( 9 ). Studies suggest that this nootropic may boost memory, mental clarity, and overall cognitive function ( 10 ).

Theacrine: This natural plant compound acts as a mild stimulant, without the tolerance build-up and jitters associated with caffeine ( 11 ). Theacrine may boost energy, mental clarity, and focus.

These supplements and packaging

What’s Good About Thesis Nootropics?

There are a lot of folks interested in nootropics. Google reports something like 100,000 monthly searches for the term each month. The issue many have is simple: nootropics aren’t easy. 

It’s not easy to know what companies are selling legitimate products and which are pushing low-grade stuff. It’s not easy to get a handle on what the many, many different nootropics are meant to do. Sometimes it’s not easy to know if the good week you just had was thanks to a nootropic you just took, or the absence of some stressor you forgot about. Then there’s dosage, doctors, and the way in which these substances play off each other to worry about. 

Getting your foot in the door with nootropics is a challenging task. Thesis’s approach is designed to simplify this, and it largely works.

The personalization is somewhat limited, in that the blends themselves cannot be changed, but the blends you receive can. Interested customers are prompted to complete a simple questionnaire that asks about physical traits as well as your goals in taking nootropics. You’re then given a “Starter Kit” that includes four different blends suited to what you’re after. 

High-quality ingredients

The more you delve into nootropics, the more you realize there are, broadly, two classes of company: the legit class and the not-so-legit class. Thesis, by our account, is the former. The company’s products are products in FDA-approved cGMP facilities, which ensures the manufacturing of the product is sound. More importantly, though, and this will sound humorous if you’ve never shopped for nootropics, Thesis actually tells you what’s in its blends. 

Thesis is not the only company selling nootropic blends as a shortcut for people not interested in doing months of research. There are a great many companies that don’t specify ingredients (“focus blend”) or, more commonly, aren’t clear on dosage of each individual nootropic.

Thesis’s nutrition label is crystal clear on what’s inside each serving of its nootropic blend.

When launching oneself into a health category one doesn’t know much about, having a friend can be helpful and reassuring. Thesis’s customer support service—available via email or phone—is the weird science friend you need. 

I pestered them numerous times and each issue was responded to and resolved within 24 hours every time. The first time I called. Is there a way to remove the caffeine from the blends (there’s 100mg, or a cup of coffee’s worth in each pack)? You can request non-caffeinated blends on your next order, but for the time being simply don’t take the white pill in the daily dose packet. My email questions were answered with similar speed as well. 

There’s also Thesis’s coaching feature, which is effectively customer service for questions about your specific blends, how the blends make you feel, and so on. When I called into it I mentioned that some of the blends made me slightly antsy, some made me feel great, and others seemed to have no effect at all. Not only is this common, it’s expected: these substances do not affect us all in the same way, so there is a necessary trial period to get through. 

Having a source of reassurance when trying something new to improve our health makes the process more comfortable. 

MENTAL WORKOUT

does thesis pills work

What’s Not Good About Thesis Nootropics?

As previously mentioned, not all blends will work for you. Several reviews online suggest there are people for which none of them will work. My fellow reviewer and I each found one or two blends that worked especially well, some blends that didn’t seem to have any effect at all, and others that caused some minor anxiety. 

This is sort of the rub with nootropics. Different people will be hit different by different nootropics ; and even then there is the matter of dosage and duration, as most research suggests there is bedding-in period associated with nootropic effectiveness ( 12 ).

So is this a con for Thesis or for nootropic supplementation more generally? It’s a little of both, but more so a hurdle with the wider world of nootropics.

If you’re already waist deep in nootropics as a hobby or interest area, you can likely build your own nootropic stacks for cheaper than what Thesis offers.

Thesis costs $79 a month, or $3.29 per serving, once you’ve set up your account for automatic renewal. This is, unsurprisingly, on the middle-higher end of the nootropic blend market. 

Budget brands like Focus Factor come in at less than a dollar per serving. Mind Lab Pro , a brand closer to Thesis’s efficacy and quality, goes for about $2.10 per serving. The popular NooCube blend is also about $2.15 per serving. 

It should be said that I’m obviously comparing apples to oranges here. Each of these blends are made of up different stuff. Each of these companies is selling to a different customer. It could be argued that Thesis’s hyper responsive customer service and task-focused personalization model makes the $79 a month bill a fair deal. That said, the price doesn’t pull you in quite like the promise the rest of the product provides. 

Thesis Nutritional facts

What It’s Like to Take Thesis Nootropics

Tester #1 info : Female, 23 years old Reason for taking : diagnosed ADHD, brain fog, difficulty concentrating, anxiety Blends taken : Confidence, Motivation, Energy, Clarity

When I was diagnosed with ADHD in 2016, everything clicked. I’ve struggled with brain fog, task paralysis, and extreme difficulty concentrating for as long as I can remember. But all I have to show for my diagnosis is a raging caffeine addiction, two failed tries at taking prescription stimulant medication, and an ever-changing-never-working supplement stack.

As a neurodivergent person, the idea of nootropics—supplements that may improve cognitive performance—is intriguing to me. The idea of spending hours researching different blends and stand alone supplements, however, is not. That’s where Thesis comes in. 

To order your four-blend starter kit, Thesis kicks things off with a quick 25-question quiz. The questions were quick and multiple choice, and didn’t take more than a couple of minutes. (As a company that markets to ADHD-ers, I have to say they know their audience.) The quiz covers questions like how much sleep you clock in each night, your typical mood, and your procrastination habits—and a memory test at the end that I won’t spoil. At the end, you plug in an email and receive a customized recommendation based on your goals and struggles. 

I’m ultra-productive, but I have extreme anxiety and frequent brain fog depending on the state of my hormones. Thesis recommended four blends—Confidence, Motivation, Energy, and Clarity—to boost my mental health, promote relaxation, and fight off brain fog. 

I took each blend for six days each—as directed—with one day in between to reset.

Week one I opted for Confidence—a blend that includes saffron, ashwagandha, sage, and magnesium—which oddly produced the opposite of its intended effect. Two days in, I ditched the separate, white caffeine pill in the packet, but that only alleviated my anxiety slightly. Week two, I took Motivation—which contains artichoke extract, vitamin B12, methylliberine, and L-theanine. I enjoyed this blend the most, and felt like my mood and concentration got a decent boost. Weeks 3 and 4 I took Energy (mango leaf extract, theacrine, citicoline, and more) and Clarity (Lion’s Mane, L-theanine, and more) respectively. I noticed no changes these weeks.

Overall, I think Thesis is worth a shot for the nootropic-curious. Especially if you don’t have the time or patience to research these trendy supplements. However, I don’t think I’ll be stocking up on any of their blends any time soon.

BRAIN GAMES

does thesis pills work

Tester #2 info : Male, 30 years old Reason for taking : brain fog, unfocused, spark creativity Blends taken : Clarity, Logic, Creativity, Energy

I’ve not been evaluated for or diagnosed with any neurological or neurodevelopmental matters, but I have struggled to train my mind’s gaze on one thing for long periods of time for as long as I can remember. Call it brain fog or something else, it’s been a persistent issue of mine going back to my high school and college years, where I’d substitute just about any distraction available to me instead of something that would require real attention.

A Thesis ad on Instagram suggested this issue may not be my own failing (a source of great personal anxiety), but perhaps something that could be fixed with nootropics. I’m willing to believe most anything that suggests my failings are not my failings, so I ordered my personalized starter kit. 

My kit came with the Clarity, Logic, Creativity, and Energy blends. I quickly eliminated Clarity and Logic from the rotation, and both seemed to trigger a mix of uncomfortable headaches and anxiety (a quick browse of the internet suggests this isn’t an uncommon reaction to these specific blends). Energy, while effective, wasn’t the most useful to me, someone who doesn’t struggle as much with alertness. 

Creativity was different, though. During the second month of testing, once I’d taken Creativity for a few weeks straight (remember there is a bedding-in period!), things started to click. I started to feel the gears turning a bit more in brainstorm meetings at work, and I could think more deeply about how I could build a workout plan for a friend.

That’s how I would describe the feeling: a noticeable but slight improvement in my ability to untangle a problem of some kind. It wasn’t as though the shackles of my brand were removed and I launched a Fortune 500 company which, thankfully, Thesis does not suggest in any of its marketing materials. 

I’ve taken the Creativity tablets for a few months now and find them to be good value for the money, for me. For those curious about nootropics, I think of Thesis as the ideal first stop. Once you figure out what works for your brain and needs, you might seek out other solutions. 

The Bottom Line

Thesis nootropics are probably the best way to get into nootropics without having to do loads of research. The brand isn’t the cheapest out there, but the product is quality and the customer service is excellent.

Lai, Puei-Lene et al (2013) https://pubmed.ncbi.nlm.nih.gov/24266378/

Skubel Tomasz et al (2022) https://www.researchgate.net/publication/363300485_Therapeutic_potential_of_Lion

Ham, Juhee et al (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645066/

Williams, Jackson L. et al (2019) https://pubmed.ncbi.nlm.nih.gov/31758301/

Lopresti, Adrian L. et al (2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/

Yurko-Mauro, Karin et al (2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364972/

Downey, Luke A. et al (2012) https://pubmed.ncbi.nlm.nih.gov/23281132/

Kumar, Navneet et al (2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/

Mashayekhu, Ameneh et al (2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163160/

Ge, Wei et al (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014356/

Bello, Marissa L. et al (2019) https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0287-6

Malik, Matej et al (2022) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415189/

About the author

Will Price is Hone Health’s Senior Lifestyle Editor. Before Hone he was Gear Patrol’s home and drinks editor.

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does thesis pills work

Thesis Nootropics Review: Unveiling the Effects on Cognitive Enhancement

Nootropics , often referred to as “smart drugs” or cognitive enhancers, have gained popularity for their potential to improve mental functions such as cognition, memory , intelligence, motivation, attention, and concentration . As an avid researcher in the field of cognitive enhancement , I have come across various products that claim to offer these benefits. Thesis, a company that provides personalized nootropic stacks, presents a unique approach to cognitive enhancement by customizing supplements to match individual needs and goals.

does thesis pills work

My personal journey with nootropics led me to investigate Thesis Nootropics further. Their promise hinges on the tailoring of their product to the user’s specific cognitive profile. This level of customization is intended to maximize the benefits while minimizing potential side effects. In reviewing Thesis Nootropics, I examined the ingredients used, the science behind them, the efficacy as reported by users, and how they compare to other products in the market.

Key Takeaways

  • Thesis provides personalized nootropic stacks to enhance cognitive functions.
  • Customization of supplements is designed to optimize benefits and reduce side effects.
  • Examining user experiences and comparative analysis is crucial in evaluating Thesis Nootropics.

Understanding Nootropics

does thesis pills work

Nootropics, often referred to as “smart drugs,” have garnered attention for their potential cognitive benefits . I’ll give you an overview of their history and types, specifically focusing on natural versus synthetic variants.

History and Definition

Nootropics, a term coined in 1972 by psychologist Corneliu E. Giurgea, refer to substances that can improve mental performance. Initially, nootropics were associated with compounds that met very specific criteria that include the enhancement of learning and memory while providing protection to the brain under various conditions. The concept has since expanded to include a variety of nootropic supplements that claim to boost cognitive functions such as memory, creativity, and motivation.

Natural vs. Synthetic

Natural nootropics are compounds found in nature such as herbs and plant extracts that may offer cognitive enhancements. Common examples include:

  • Ginkgo Biloba: Often used with an aim to improve memory.
  • Panax Ginseng : Sought for its potential to boost brain function.

Conversely, synthetic nootropics are manufactured compounds like racetams and amphetamine derivatives. They include:

  • Piracetam: The first synthetic nootropic, designed to aid in memory and learning.
  • Modafinil: Prescribed for sleep disorders but often used off-label for its concentration-enhancing effects.

Both types aim to offer cognitive benefits, but their effects and mechanisms can widely differ. Natural nootropics are typically preferred by those seeking milder effects and a more holistic approach, whereas synthetic ones are chosen for their strong, targeted actions.

Thesis Nootropics Specifics

I’ve researched Thesis Nootropics intricately to provide accurate details on their product lineup, the customization process, and the intricacies of their subscription model.

Product Offerings

Thesis Nootropics presents a range of dietary supplements, each targeting specific cognitive functions. Their offerings typically include Thesis Energy , designed to boost stamina and focus , Thesis Clarity , intended to enhance cognitive sharpness, and Thesis Motivation , aimed at increasing users’ drive and productivity. The ingredients in these supplements range from natural extracts to amino acids , all selected for their potential nootropic properties.

  • Thesis Energy : Ingredients such as caffeine and L-theanine
  • Thesis Clarity : Includes nootropics like Rhodiola Rosea
  • Thesis Motivation : Features compounds such as sulbutiamine

Thesis Customization

The cornerstone of Thesis Nootropics is personalization. Upon embarking on their nootropic journey, customers receive a starter kit which allows them to test different ingredients and track their effects. This process is critical in developing personalized blends that match individual cognitive needs and goals. I appreciate that this approach acknowledges biological uniqueness and optimizes supplementation for personal effectiveness.

Subscription Model

Thesis offers their nootropic supplements through a monthly subscription model. After the initial starter kit evaluation phase, customers receive monthly deliveries of their tailored supplements. Subscriptions provide convenience and ensure continuous use for consistent cognitive support. This model necessitates a commitment but also emphasizes regularity in pursuing cognitive enhancement.

  • Monthly Deliveries: Ensures a steady supply of personalized nootropic blends
  • Subscription Cycles: Typically require a monthly payment with the flexibility to pause or cancel

The focus on specifics ensures that you possess a clear understanding of what Thesis Nootropics brings to the table in terms of products, customization, and purchase options.

Benefits and Efficacy

In evaluating Thesis Nootropics, I’ve found that the primary benefits are centered around enhancing cognitive function and managing mood and stress, both essential for optimal mental performance.

Cognitive Function Enhancement

Energy & Concentration: Users report heightened energy levels, which appear to correlate with an increased ability to focus and maintain concentration. This makes tackling complex tasks somewhat easier.

Memory & Clarity: Memory recall and mental clarity are also areas where Thesis Nootropics shows potential. My review notes improvements in these domains, supporting better retention of information and clearer cognitive processing.

Motivation & Creativity: There’s mention of an uptick in motivation, alongside a conducive environment for creativity. This is pertinent for those requiring innovative thinking in their daily activities.

Mood and Stress Management

Mood Improvement : Regular intake of Thesis Nootropics may lead to a stabilized and improved mood, as suggested by my analysis and user testimonials. This is vital for sustained cognitive performance.

Stress Reduction: Stress levels reportedly see a downward trend with these nootropics. My observations concur, and lower stress is indispensable for reducing cognitive friction and the dreaded brain fog.

Potential Side Effects and Safety

In assessing the side effects and safety of Thesis Nootropics, I focus on the documented experiences of users and the available clinical evidence supporting safety claims.

Common Concerns

Side effects : In my examination, users have reported various side effects that may include headache , anxiety, and jitteriness—typically associated with products containing caffeine . While individual tolerance varies, I have observed these reports to be relatively infrequent.

  • Headache : Possible in sensitive individuals or new users.
  • Anxiety : Can occur, particularly in formulations with high stimulant content.
  • Interactions : As with any supplement, a check for potential interactions with prescription medication is prudent.

Clinical Evidence

Clinical Trials : Thesis Nootropics’ safety profiles are often supported by studies on individual ingredients rather than on the products themselves. Comprehensive, product-specific clinical trials that are peer-reviewed and FDA-recognized remain limited.

  • Caffeine : Investigations affirm it’s generally safe in moderate amounts; however, excessive intake can lead to side effects.
  • FDA Oversight : Dietary supplements like Thesis Nootropics are not as stringently regulated as prescription medications, hence the FDA does not approve them. However, safety can be inferred from the FDA’s guidelines on individual ingredients.

Comparative Analysis

In this section, I examine how Thesis Nootropics stack up against other prominent brands in the market and assess their value for money.

Thesis vs. Other Brands

Thesis Nootropics stand out due to their personalized approach to cognitive enhancement. Customers complete an assessment that tailors the nootropics stack to their individual needs.

  • Mind Lab Pro offers a universal nootropic aiming to target all areas of cognitive function without personalized stacks. It has received acclaim for its comprehensive formula .
  • Onnit’s Alpha Brain is another competitor, well-known for celebrity endorsements and a formula that supports memory, focus, and cognitive processing without the need for personalization.

When looking at customer reviews , Thesis seems to have a strong following due to its bespoke service. On the other hand, both Mind Lab Pro and Alpha Brain have amassed numerous reviews praising their effectiveness for a broader audience.

Pros of Thesis: personalized approach, tailored benefits. Cons of Thesis: may be costlier due to customization, less known than other brands.

Pros of Mind Lab Pro: broad-appeal formula, strong market presence. Cons of Mind Lab Pro: lacks personalization, potential overkill of ingredients for some.

Pros of Alpha Brain: popularized by endorsements, focus on cognitive processing. Cons of Alpha Brain: potential variability in individual results, less tailored experience.

Cost-Benefit Consideration

When I consider the price of Thesis, it is generally on the higher side due to the personalized nature of the product. However, my logic dictates that the cost could be justified if the tailored stacks lead to more noticeable improvements in cognitive function.

  • Thesis sells their personalized nootropics starting at a certain price point that can go up depending on the customization.
  • Mind Lab Pro comes at a set price, positioning itself as a one-size-fits-all solution, potentially more cost-effective for those not seeking personalization.
  • Alpha Brain is similar to Mind Lab Pro in pricing but frequently offers deals and discounts which may make it a more attractive option for budget-conscious consumers.

To decide if Thesis is worth it , compare:

  • Price: Higher for customization.
  • Buy: Direct and through subscriptions for ongoing benefits.
  • Reviews: Positive for the personalized approach.
  • Comparison: More expensive than some, but the cost is justified for users who value bespoke formulas.

The deciding factor often comes down to whether an individual prefers a personalized approach or a generalized formula that has been traditionally popular in the market.

User Experience and Reviews

In this section, I will provide a detailed look at what consumers and professionals are saying about Thesis Nootropics. I seek to offer a balanced and informed perspective on the real-world impact these supplements have on cognitive performance.

Customer Testimonials

Thesis Nootropics have been met with a broad spectrum of feedback from users who typically emphasize gains in focus, clarity, and energy levels. Below is a curated selection of customer testimonials:

Professional Opinions

In the realm of expert analysis, coaches and neuroscientists have offered their professional outlook on Thesis Nootropics. The consensus is that these supplements provide a tailored approach to cognitive enhancement, by customizing nootropic blends to individual needs.

  • Dr. Aiden Smith, Neuroscientist : “Thesis Nootropics offer an innovative approach to cognitive support, backed by scientific research in neurology.”
  • Coach Jennifer Lynn , Cognitive Performance Coach: “My clients report clear, sustained focus and improved mental energy when incorporating Thesis into their wellness routine.”

Frequently Asked Questions

In this section, I provide answers to some of the most common inquiries regarding Thesis nootropics. I focus on ingredients, comparisons with pharmaceuticals, potential benefits, side effects, user feedback, and top-rated alternatives for cognitive enhancement.

What are the main ingredients in Thesis nootropics and how do they work?

The main ingredients in Thesis nootropics include a range of vitamins, amino acids, and herbal extracts, each serving a specific function. Ingredients like Rhodiola and Bacopa enhance memory and focus, while L-Theanine and caffeine stimulate alertness and cognitive performance.

How do Thesis nootropics compare to Adderall in terms of effects and safety?

While Adderall is a prescription medication primarily used to treat ADHD, Thesis nootropics are over-the-counter supplements aimed at boosting cognitive performance. Adderall contains amphetamine salts, which have a significant impact on neurotransmitters but also carry a higher risk of side effects and dependency. Thesis nootropics offer a milder, non-prescription alternative with a focus on safety and minimal side effects.

Can Thesis nootropics potentially improve attention and focus in individuals with ADHD?

Some users with ADHD may find the ingredients in Thesis nootropics beneficial for improving attention and focus. However, Thesis products are not approved as a treatment for ADHD by the FDA, and individuals with ADHD should consult with a healthcare provider before using these supplements.

What are the reported side effects of taking Thesis nootropics?

The reported side effects of Thesis nootropics tend to be mild and can include jitteriness, stomach upset, or headaches. These are typically dosage-dependent and can often be mitigated by adjusting the intake.

How effective are Thesis nootropics according to user reviews?

User reviews generally suggest that Thesis nootropics are effective for enhancing cognitive functions such as focus, memory, and mental clarity. Effectiveness can vary individually, but many users report noticeable improvements after consistent use.

What nootropic is considered the highest-rated for cognitive enhancement?

While individual experiences may vary, many users and experts consider modafinil to be one of the highest-rated nootropics for cognitive enhancement. It is often praised for its ability to increase wakefulness, focus, and productivity. However, it is important to note that modafinil is a prescription medication and should be used under medical supervision.

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COMMENTS

  1. Thesis Nootropics Review - Must Read This Before Buying

    Get a detailed honest Thesis Nootropics Review. Here's what you need to know before you buy. Get full customer ratings, coupons, return policy, and more.

  2. Thesis Nootropics Review: Tested In 2024 – Forbes Health

    Thesis nootropics are designed to enhance specific elements of brain health, from focus to energy. To get started with Thesis, you can take an online survey or choose your own blends.

  3. Thesis Nootropics Review | Custom Brain Boosters [2024]

    Thesis Clarity relies on 7,8 DHF (dihydroxyflavone), Alpha GPC (glycerylphosphorylcholine), epicatechin, and lion's mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention.

  4. I Tried 4 Thesis Nootropic Blends (My 2024 Review)

    What Is Thesis Nootropic And What Does It Do? Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Depending on the blend chosen, users can expect improvements in focus, reduction in procrastination, stress management, and memory recall. Does Thesis Work Like Adderall?

  5. Thesis | Personalized nootropics for every brain

    Fight your fatigue. Sharpens energy and strengthens stamina. Try Energy. We formulate potent nutrient compounds to enhance mental performance and make personalized recommendations based on your goals and unique brain chemistry. Tell us about yourself and your goals.

  6. Thesis Nootropics Review 2024: Honest Thoughts + Am I Still ...

    Does Thesis work like Adderall? Thesis will not be as potent as Adderall, a prescription medication. However, Thesis , a type of nootropic or “smart drug,” may work well for some individuals in boosting cognitive function, focus, and more.

  7. Thesis Nootropics Helped Me Ditch My 3-Coffee-A-Day Habit

    It works like a process of elimination — you experiment by taking each supplement for six days to see whether or not it feels effective. The Thesis line features eight different supplement...

  8. FAQ – Thesis

    Does Thesis replace my ADHD medication? Our blends and many stimulant or non-stimulant medications will impact the same neurochemical systems (e.g., dopamine, norepinephrine, and serotonin) involved in mood, attention, energy, and focus.

  9. Thesis Nootropics Review (2024): Do The Brain Boosters ...

    Nootropics are the buzzy brain-boosting substances of the moment, and Thesis attempts to match people to different nootropic blends designed for certain needs—creativity, confidence, energy, clarity, logic, and so on. But can you really summon the powers of creativity on demand from a pill?

  10. Thesis Nootropics Review: Unveiling the Effects on Cognitive ...

    Thesis, a company that provides personalized nootropic stacks, presents a unique approach to cognitive enhancement by customizing supplements to match individual needs and goals. My personal journey with nootropics led me to investigate Thesis Nootropics further.