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ISSN (Online): 0975-8232, ISSN (Print): 2320-5148

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH

International Journal Of Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly An Official Publication of Society of Pharmaceutical Sciences and Research

Overview of oral dispersible tablets.

The need to deliver pharmaceuticals to patients quickly and with minimal side effects has driven pharmaceutical companies to invest in the development of novel drug delivery systems. Solid dose forms, such as pills, are difficult for pediatric and geriatric patients to swallow. The best treatment for this issue is a mouth dissolving pill that dissolves or disintegrates quickly in the oral cavity. Additionally, they produce a pleasant tongue sensation. ODT has benefits like enhanced Bioavailability, rapid action, and patient compliance. As a result, mouth-dissolved tablets are a desirable substitute for liquid and traditional tablet dose forms. In recent past, several manufacturing technologies such as sublimation technique, spray drying technique etc. are employed to overcome the limitations of conventional tablet dosage forms. The mouth dissolving tablets must undergo a variety of evaluations after they are created in order to ensure their long-term stability and improved therapeutic effectiveness.

Article Information

Page No: 1340-1345

Size: 646 KB

Download: 11

Cited By: 0

Language: English

Licence: IJPSR

Authors: Preeti Sharma

Authors Address: Ram Gopal College of Pharmacy, Sultanpur, Gurugram, Haryana, India.

Email: [email protected]

Received: 30 September 2023

Revised: 02 April 2024

Accepted: 12 April 2024

DOI: 10.13040/IJPSR.0975-8232.15(5).1340-45

Published: 01 May 2024

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International Journal of Pharmaceutical Research (ISSN: 1674-0440). People from various avenues of pharmacy profession, who have come together in a single platform to redefine the structure of pharmacy profession in the country, where it is seen only as an industry oriented profession. IJPR is peer reviewed online journal which is also available in print version. The motto behind the journal is to help students, researchers and scientist worldwide to benefit from the high quality peer reviewed articles and to their high performing works in the entire arena of pharmaceutical science.

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Requirements and challenges of multicultural education in iran, clinical response and toxicities of tkls in advanced medullary thyroid cancer: systematic review and meta-analysis, a systematic and meta-analysis of survival and failure rates of orthodontic temporary anchorage devices in children, the efficacy of renin angiotensin system inhibitors (rasi) in patients with coronary artery disease without heart failure: systematic review and meta-analysis, different scaling approaches used in pediatric pharmacotherapy as well as their proper implementation in drug development and clinical use systematic review and meta-analysis, islamic medicine during the caliphs, gender differences in happiness among the nurses, clinical applications f artificial intelligence in dental and maxillofacial radiology among children: a systematic review and meta-analysis, investigating the dimensions of patient safety indices, epidemiologic study of acute and chronic brucellosis in patients referred to yasuj shahid mofateh clinic from september 2018 to march 201997, evaluation of image quality of the heart spect by modifying the imaging protocol: a phantom study, effect of oral progesterone (dydrogestron) on incidence of glucose intolerance in pregnant females with threatened abortion referred to clinics of shiraz medical university hospitals, impact of individual and social consequences of prayer on the health of the body and soul, with emphasis on the teachings of razavi, a study on the pattern of inotropes use in an intensive care unit, due of aminoglycosides in patients admitted to icu of the shiraz namazi hospital, clinical and functional parallels of severe uncontrolled asthmain children, role of transforming growth factor beta 1 in non alcoholic fatty liver diabetes patients, hepatic and renal status of patients with sickle cell-β thalassemia in thi-qar province/iraq, prevalence of tubal blockage via hystero salpingography in iraqi infertile women, effect of isosorbide dinitrate in lipid profile and oxidant-antioxidant markers of hypercholesterolemia female rats, molecular characterization of ctx-m-15 β-lactamase from clinical isolate of klebsiella pneumoniae sj16, correlation between serum nitric oxide levels and lipid profile in several types of arterial occlusion in atherosclerosis cardiovascular patients, synthesis and identification of new organoselenium compounds derived from 4-[chloromethyl]-2-hydroxybenzaldehyde, synthesis and characterization of some new 3, 4dihydropyrimidinone derivatives, rules and regulations of the hospital, development and evaluation of natural cosmeceutical ingredients as makeup remover to prevent hyperpigmentation.

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Core components of pharmacist-led medication reviews and their relationship to outcomes: a systematic review

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M E Craske, W Hardeman, N Steel, M J Twigg, Core components of pharmacist-led medication reviews and their relationship to outcomes: a systematic review, International Journal of Pharmacy Practice , Volume 32, Issue Supplement_1, April 2024, Pages i52–i53, https://doi.org/10.1093/ijpp/riae013.066

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Medication reviews are a recognised intervention undertaken by healthcare professionals to support patients prescribed multiple medicines or with complex medication regimens. Pharmacist-led medication reviews are now an established intervention in policy and practice. There are different types of medication review, each implemented differently. Huiskes et al . demonstrated that medication reviews undertaken by any professional in any setting had minimal effects on clinical outcomes and that evidence is lacking about their effect on economic outcomes. [1] The implementation of medication reviews in practice was recognised as a factor which may impact outcomes, but this has not been explored further.

To develop an initial programme theory that links the core components of pharmacist-led medication reviews to outcomes in different contexts.

A systematic review was conducted to identify randomised controlled trials of medication reviews in adults (18+). The review updated that by Huiskes et al . and used the same search strategy in the MEDLINE, EMBASE and Web of Science databases. [1] The search terms used were related to ‘medication review’, ‘pharmacist’ and ‘randomised controlled trial’. Medication review was defined as “ a consultation between a pharmacist and a patient to review the patient’s total medicines use with a view to improve patient health outcomes and minimise medicines related problems ”. Studies reporting any outcomes were included. Papers not published in English or not available as full texts were excluded. The Cochrane Risk of Bias 2.0 tool was used to assess the studies. Data were extracted using a previously piloted bespoke data collection form. Descriptions of the medication reviews’ core components, implementation and outcomes were narratively synthesised to draw out common themes. The GRADE framework informed the overall assessment of the quality of the evidence from the studies. [2]

Records screened n= 10947, total reports of studies included n= 68. Of the 50 individual studies that were identified, 66% were assessed as having a high risk of bias. Narrative synthesis of the data extracted relating to the description and implementation of the medication reviews, and where and how this may have affected outcomes, is presented in our programme theory as core components. Collaborative working may help reduce medicines-related problems and number of medicines prescribed. Patient involvement in goal setting and action planning may improve patients’ ability to take medicines as prescribed and help them achieve their treatment goals. Additional support and follow-up may lead to improved blood pressure, diabetes control, quality of life and a reduction of medicines-related problems.

This is an extensive systematic review that has explored pharmacist-led medication reviews in all settings and resulted in the production of a draft programme theory. It is best practice for stakeholders to be involved in the development of a programme theory. Providers of medication reviews can evaluate their processes and consider if and how these core components are implemented in their service provision. This initial programme theory will be refined and discussed in future research.

1. Huiskes VJB, Burger DM, Van Den Ende CHM et al . Effectiveness of medication review: A systematic review and meta-analysis of randomized controlled trials. BMC Fam Pract. 2017;18.

2. Guyatt GH, Oxman AD, Kunz R et al . Going from evidence to recommendations. BMJ. 2008;336:1049–51.

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