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Altasciences conducts contract clinical research to assess the safety and effectiveness of new medications. We are always recruiting participants to take part in clinical studies. We are interested in healthy adult participants, as well as those with a specific illness or medical condition depending on the needs of each trial.

We are committed to your safety and comfort during our trials.

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Altasciences has clinics in both the U.S. and Canada, where experienced medical and clinical professionals oversee all aspects of trial conduct. Click on your location to see the open trials we are recruiting for:

KANSAS CITY

10103 Metcalf Avenue Overland Park, KS 66212 U.S.A.

Phone: 913 696-1601

Participant Website

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Phone: 514 381-2546

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Phone: 714 252-0700

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Gain research and teaching experience within your program by becoming a graduate research assistant, graduate teaching assistant or graduate assistant. Visit the KU Jobs website for opportunities outside of your graduate program.

Find a Trial

Clinical trials in kansas.

Are you looking to enroll in a clinical trial in Kansas? With new trials like " Changing the Default for Tobacco Treatment " and " Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients ", the Sunflower State has established itself as a great location for clinical research studies, particularly in cities like Kansas City and Wichita.

While some individuals are looking for paid clinical trials, others want to help advance immunology and pharmacology clinical research in Kansas. To begin your search for Kansas clinical trials, use the form on the right.

Use our guide to learn which trials are right for you!

We've found 2,840 clinical trials in kansas.

Select your condition

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• Kansas Studies Institute
• Scholarly Research

The Kansas Studies Institute at JCCC promotes research and teaching on the culture, history, economics and natural environment of Kansas.

Kansas Studies Institute, founded in 2009, fulfills its mission by collaborating with individuals and entities both at JCCC and throughout Kansas to expand our understanding of the state’s peoples, places, and landscape. Tai Edwards is the director.

Kansas Cosmos

KSI is coordinating a multi-disciplinary project where students are creating a to-scale version of the solar system that maps over the state of Kansas. Imagine driving on I-70 across the state and having this app tell you where you are in the solar system, when you reach the orbit of each planet/object, and the relative size and other interesting facts about each object. In 2020 students began designing, coding, researching, writing, and building the application. We soft-launched the app/website on Kansas Day, Jan. 29, 2021, and will continue building and updating it throughout the spring semester. Read about our progress or visit kansascosmos.org .

Watch a highlight video of our work so far  

In ‘zhúje ‘waxóbe/Sacred Red Rock Project

Kansas Studies Institute is a collaborator on the Mellon Foundation grant project In ‘zhúje ‘waxóbe/Sacred Red Rock. This two and a half year project builds on the work of the “Between the Rock and a Hard Place”/Robinson Park project, on which KSI also collaborated. Members of the Kaw Nation, the City of Lawrence, University of Kansas, Kanza Heritage Society, and others will relocate In ‘zhúje ‘waxóbe, a 28-ton red Siouxan quartzite boulder from Robinson Park in Lawrence, to the Kaw Nation’s Allegawaho Memorial Heritage Park near Council Grove. Interpretation, community engagement, and the development of educational materials will also be part of this project.

Visit Sacred Red Rock project’s website to learn more

Visit the Robinson Park project’s website to learn more

Other recent projects include:

• Tai Edwards shared a Big Idea on the Humanities Kansas website: How Should We Honor Someone's Military Service?
• Recording oral histories. This began with Vietnam-era veterans in “Kansas Stories of the Vietnam War” – a Humanities Kansas project. KSI has continued this work, recording oral histories with veterans of any era. KSI also partnered with Special Olympics Kansas on “Celebrating Inclusion Since 1970: A Special Olympics Kansas Oral History.”
• Production assistance for Kansas-themed documentaries.
• Hosting lectures on a variety of Kansas topics, such as depletion of the Ogallala aquifer, artistic representations of Kansas, and Quindaro Townsite preservation.
• Commissioning and maintenance, including prairie burning, of Stan Herd’s “earthworks” installation titled  Kansa , on the southwestern side of the JCCC campus.
• Traveling with students and teaching coursework on the state.
• Student internships involving a range of opportunities, including researching and designing installations in celebration of JCCC’s 50th anniversary; publishing peer-reviewed scholarship; and assisting in the Johnson County Trails Project that posts historic signage around the county’s hiking trails.
• Annual programming on Kansas Day, Jan. 29 – the date Kansas became a state.

Much of this great work can be accessed through the Kansas Studies Institute digital archive, available through JCCC’s Billington Library   and on the Kansas Studies Institute playlist on JCCC's YouTube channel .

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Director: Tai Edwards Phone: 913-469-8500, ext. 4505 Location Bldg: OCB 234

Kansas City (Overland Park), Kansas

Velocity clinical research, kansas city.

Velocity’s Allergy and Asthma research site in Overland Park, KS partners with Kansas City Allergy and Asthma Associates, P.A. (KCAA) to conduct clinical trials for investigational products intended to help treat allergies, asthma, immunologic diseases, and related conditions. The area’s premiere provider of allergy and asthma care, the site is easily accessible to thousands of patients, including those established with the practice. KCAA has served the community since 1979, and began conducting clinical trials with Meridian Clinical Research in 2022, shortly before being acquired by Velocity.

All trials conducted at the site are performed in accordance with ICH and FDA guidelines, and in compliance with GCP. The Kansas City team is committed to being a resource for study participants, to providing the highest quality of patient care with compassion and kindness, and to advancing medicine through research.

Velocity Clinical Research, Kansas City 8675 College Blvd, Suite 200, Overland Park, KS 66210

Phone: (913) 408-5501

Email: [email protected]

Find a Clinical Trial in Kansas City (Overland Park) Use the dropdown to browse current studies in Kansas City (Overland Park).

Follow Velocity on Facebook for company updates and more.

About Velocity Clinical Research

155,000+ people have a joined a study at velocity.

Many people enjoy the study experience and have joined several clinical trials at Velocity.

Velocity has decades of research experience

With sites that were established as long ago as 1986, Velocity has experts who have supported clinical trials for decades.

Velocity studies are led by healthcare professionals

All clinical trials conducted at Velocity are overseen by the U.S. Food and Drug Administration (FDA).

Our experienced research team in Kansas City (Overland Park)

Every clinical trial is overseen by a Principal Investigator – a physician who is responsible for the rights, safety and welfare of the study participants. All physicians at Velocity are board certified in their specialty area(s) and all research staff is trained in clinical research regulations, including GCP and HIPAA. Our clinical research team in Kansas City (Overland Park) is dedicated to conducting quality research in a professional and caring environment.

Derrick R. Ward, MD

Principal Investigator Board certified in internal medicine and allergy, asthma, and immunology, Derrick R. Ward, MD received his medical degree from Southern Illinois University School of Medicine. He completed an internal medicine residency at John’s Mercy Medical Center in St. Louis and an allergy/immunology fellowship at Children’s Mercy Hospitals and Clinics in Kansas City. Dr. Ward is a member of the American Academy of Allergy, Asthma and Immunology, the Joint Council of Allergy, Asthma and Immunology, the American College of Physicians, the American Medical Association, the Greater Kansas City Allergy Society, and a fellow of the American College of Allergy, Asthma and Immunology.

James B. Sterner, MD

Principal Investigator James B. Sterner, MD joined KCAA in 2014. Board certified in internal medicine and allergy as well as asthma and immunology, Dr. Sterner received his medical degree from University of Missouri-Columbia School of Medicine. He also completed an internal medicine residency at Brooke Army Medical Center, Fort Sam Houston, Texas and an allergy and immunology fellowship at Walter Reed Army Medical Center in Washington, D.C. Dr. Sterner is also a member of the American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology.

William J. Lavery, MD, PhD

Principal Investigator William J. Lavery, MD, PhD is a board-certified pediatrician with fellowship training in adult and pediatric allergy, asthma and immunodeficiency. Dr. Lavery is also board-eligible in allergy and immunology. He received his medical degree from University of Texas School of Medicine and completed a pediatrics residency at University of Colorado/Children’s Hospital Colorado as well as an allergy and immunology fellowship at University of Cincinnati/Cincinnati Children’s Hospital Medical Center. Dr. Lavery is a member of the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), and the American Academy of Pediatrics (AAP).

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Clinical Research Careers

Lyme Disease: What You Need to Know About Transmission, Long-Term Effects, and Lyme Disease Vaccines

Learn more about participating in a clinical trial.

Liver disease is a growing concern across the globe, especially in the United States, where the prevalence of conditions like Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis … Read more

What is Informed Consent?

Joining a clinical trial is an important decision. Most participants come to the clinic with questions about clinical trials and what joining one could mean. This is why every study … Read more

Clinical Trial Phases: What Happens in Phase 1, 2, 3 and 4?

Clinical trials are research studies of medications, vaccines, medical devices, procedures, diagnostics (tests), and other health-related products. These studies involve participants (also known as patients, volunteers, or subjects) to determine … Read more

Participant Story: Maryann, a Research Study Participant at Velocity

What led you to participate in a research study? I saw a roadside poster near the university in my neighborhood [for a vaccine study] and called Velocity. My first experience … Read more

Complete the form to start your clinical trial journey in Kansas City (Overland Park)

Why join a clinical trial?

• Help advance medicine
• Learn about potential new medicines in development
• Get study-related medical exams at no cost
• Receive compensation for participating (available amounts may differ for each study)

After you submit your info, a Velocity staff member will review your info. They will contact you to talk about the study, or others that may be right for you.

Health insurance is generally not needed to join a clinical trial.

Remember, there is never an obligation to join — we're here to help you make the best decision.

Submit your info

By entering your email address and/or phone number on this form, you represent that you are at least 18 years of age and consent to receiving communications (e.g., call, SMS, text, and/or email) from Velocity and/or the research site(s) involved with the clinical trials that appear on this website. Message and data rates may apply. You may reply with STOP to a text message. For full details, refer to Velocity's privacy policy and website terms of use . Submissions on this website are not monitored 24/7. Do NOT submit personal health or medical information on this form. If you are enrolled in a trial and have questions, please call your research site.

Sponsors and CROs

From the leading pharma companies, to the most pioneering biotech startups, Velocity supports those who are exploring new frontiers in human health. Whether you’re ready to conduct a single-site study or a complex, high-volume clinical trial, trust Velocity.

It all starts with people like you.

Without clinical trial participants, it would not be possible to create new medicines, treatments, and cures..

Bringing better medicine to life.

Center for pharmaceutical research is now amr kansas city . . . help others through the vital clinical research taking place in kansas city., research studies may test new drugs, medical devices, medical interventions or investigate vaccinations..

Center for Pharmaceutical Research is now AMR Kansas City. We may have a new name, but we’re still the same full service clinical research site that delivers high quality research services through a highly trained, experienced and dedicated staff.

AMR Kansas City conducts and manages the day-to-day clinical research trial at the investigative site level under the direction of the principal investigator. We handle all regulatory correspondence, contracts and budgets, plus training and placement of study-dedicated research coordinators. We recruit participants, gather data, provide complete documentation and follow study participants.

Clinical research matters.  You matter.

Clinical research matters because it makes healing possible. Without it, a broken arm would remain broken. A common ailment would go untreated.  A cancer patient would have no hope for a cure. It has to start somewhere.  It has to start with someone.

Will that someone be you?

A leader in the fight against COVID-19.

A wide-range of therapeutic areas., help others through clinical research..

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Paid Clinical Trials in Kansas City, MO

Find paid studies that are recruiting healthy participants in Kansas City, MO. Filter by distance, duration, and inclusion criteria to find clinical trials that pay well for your time.

Here are the 6 most popular medical studies in paid studies kansas city

Michael Bask Gill, B Sc

Last Reviewed: March 18th, 2024

Development of AD/OI after BS. for Orthostatic Intolerance

Observational two phase, retrospective and prospective registry study to assess the prevalence of and characterize outcomes of autonomic dysfunction (ad) in patients who undergo bariatric surgery (bs) and to better define the underlying pathophysiology of ad following bs..

Behavioral Intervention

High-intensity interval training +1 more for stroke, this trial will study stroke survivors who still have trouble walking. they will be randomly placed in either a moderate or vigorous walking exercise group. the exercises will be done with a physical therapist for 45 minutes.

Behavioural Intervention

Gait training for stroke, this trial aims to see if a walking training program can improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a cycling exercise. participants will walk on a treadmill with support and a special.

Felix NeuroAI Wristband for Essential Tremor

This trial aims to see if the felix neuroai wristband is a safe and effective treatment for patients with essential tremor. participants will be given either the felix device or a sham device for up.

LY3841136 for Obesity

This trial aims to study the effectiveness and safety of ly3841136 for managing weight in adults who are overweight or have obesity. the study will last for about 64 weeks and participants may need to.

AXS-05 for Depression

This trial is being conducted to see if a new medication called axs-05 is effective in preventing the return of depressive symptoms in people with major depressive disorder. the study will compare axs-05, popular filter options for paid studies kansas city trials, phase 3 clinical trials.

View 93 phase 3 medical studies.

Monoclonal Antibodies

Azd0901 for stomach cancer, this trial aims to compare the effectiveness and safety of azd0901 with other treatment options for patients with advanced stomach or gastroesophageal junction cancer that has spread, and that expresses a specific protein.

RNA-targeted therapy

Lepodisiran for elevated lipoprotein, this trial aims to test whether lepodisiran can reduce the risk of heart disease in people with high lipoprotein(a) levels who already have heart disease or are at risk of a heart attack.

Corticosteroid

Budesonide +1 more for chronic obstructive pulmonary disease, this trial will compare the effect of using a combination inhaler (bgf) containing three types of medication versus a different combination inhaler (gff) in people with copd and high risk for.

Combination Therapy

Icosema +1 more for type 2 diabetes, "this trial will compare a new medicine called icosema, which is a combination of insulin icodec and semaglutide taken once a week, to insulin glargine taken daily in.

GLP-1 Receptor Agonist

Cagrilintide +2 more for type 2 diabetes, this trial will test how well a new medicine called cagrisema helps people with type 2 diabetes to lower their blood sugar and body weight. cagrisema is not yet approved.

Growth Factor

Efruxifermin for nonalcoholic steatohepatitis, this trial is evaluating the effectiveness of a drug called efruxifermin in treating a liver condition called non-cirrhotic nash/mash with fibrosis stage 2 or 3, clinical trials with no placebo.

View 93 medical studies that do not have a placebo group.

Phosphodiesterase Inhibitor

Sildenafil +1 more for fontan circulation, "this trial will study how liver congestion and fibrosis affect how drugs are processed in the liver in young patients with fontan circulation.".

Sleep health enhancement intervention for Sleep Hygiene

This trial aims to develop and test a program to improve sleep in adults aged 45-64 in order to potentially delay or prevent alzheimer's disease. the study will focus on the feasibility, acceptability.

Miebo for Dry Eye Syndrome

This trial aims to assess the effectiveness of miebo™ in treating dry eye disease in a real-world setting., car t-cell therapy, bms-986393 for multiple myeloma, this trial aims to test how well bms-986393 works and how safe it is for people with multiple myeloma that has come back or not responded to previous treatment..

Cost Communication and Financial Navigation (CostCOM) for Cancer

This trial looks at how a program called cost communication and financial navigation (costcom) can help cancer patients with their medical costs and financial stress. cancer patients often struggle with high medical costs and financial difficulties, paid clinical trials.

View 93 medical studies that offer remuneration.

CS-1103 for Substance Use Disorder

This trial will test how safe and well-tolerated a new drug, cs-1103, is when given in increasing doses through a vein to healthy volunteers..

Anti-tumor antibiotic

S-337395 for healthy subjects, this trial aims to study different versions of a drug called s-337395..

LAD603 for Healthy Subjects

This trial aims to determine if lad603 is safe and well-tolerated at different doses in healthy adults. it will also examine how the drug is processed in the body and its effects on the.

VX-828 for Cystic Fibrosis

This trial is being conducted to test the safety, side effects, and how the drug vx-828 is processed in the bodies of healthy individuals..

Cancer Vaccine

31-valent pneumococcal vaccine for preventing pneumococcus-related diseases, this trial tests the safety and effectiveness of a new vaccine in adults 50-64, compared to the existing prevnar 20 vaccine., view more paid studies kansas city trials.

See another 71 medical studies focused on paid studies kansas city.

Placebo +1 More

Alagille syndrome (ALGS)

Non-HEMT/Control Group

High-Risk Cardiac Device Recipients

Smoking Abstinence (non-menthol) +3 More

COVID-19 Vaccine +3 More

Sacituzumab Govitecan

Subjects successfully implanted with an Abbott Assert-IQ ICM device

Efruxifermin

Disitamab Vedotin

Simultaneous UroLift™ and HoLEP

Umbilical Cord Clamping at ~30 seconds +2 More

Lorundrostat

Cohort A - Historical Cohort

Treatment Group

JNJ-77242113 +1 More

RSV/hMPV vaccine candidate

Expanding Communication and Language Generated in Conversation Treatment (ECoLoGiC Treatment)

AMG 355 +1 More

Volrustomig

LY3305677 +1 More

Episodic Future Thinking

AZD5305 +1 More

Pembrolizumab +1 More

More and Less Social Comprehension

Povorcitinib

Patient Navigation

Livmoniplimab +1 More

Miricorilant

Onvansertib

One arm pilot trial

Naltrexone-Bupropion (NB) Combination

Participants

Bexotegrast (PLN-74809)

Resistance Training

JNJ-77242113

Aficamten +1 More

LockeT Device

Tirzepatide

LY3556050 +1 More

Portable MRI Arm

SV-BR-1-GM +1 More

Ritlecitinib

VK2735 +1 More

Pregnancies with GDM and BMI > 30

Eye Gaze Technology

CagriSema +3 More

Whole-body Electrical Muscle Stimulation Exercise

Risankizumab

Left atrial appendage closure

Patients with PVCs

View more paid studies kansas city

See more medical studies focusing on paid studies kansas city

Frequently Asked Questions

Other Trials to Consider

VTX958 Dose A

Transcatheter aortic valve replacement (tavr), j-valve tf system, amplatzer valvular plug iii, jenavalve pericardial tavr system, computerized auscultation, accucinch® ventricular restoration system, tendyne mitral valve system, nap first, then umpc, cephea mitral valve system, edwards sapien 3 transcatheter valve, model 9600tfx, cardiomech mvrs, edwards aortic and mitral bioprostheses models 11000a and 11000m, harmony tpv system, popular categories.

Clinical Trials in Kansas City, MO

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Clinical Trials in Kansas

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Clinical Trials in New Hampshire

Paid Clinical Trials in Houston, TX

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Paid Clinical Trials in Virginia

Paid Clinical Trials in Kansas

Paid Clinical Trials in Mississippi

Paid Clinical Trials in New Hampshire

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Popular guides.

K-State partners with University of Kansas Health System to support rural health care, communities

MANHATTAN, Kan. (WIBW) - Kansas State University and the University of Kansas Health System announced a partnership that will involve supporting rural health care and communities.

On Thursday, April 4, K-State and the University of Kansas Health System provided a news conference about their partnership and what it will look like in the next six months to a year.

The partnership is a first-of-its-kind collaboration that brings together the land-grant mission and statewide presence of K-State through K-State Research and Extension with the expertise and experience of the state’s only academic health system.

“Our partnership with the University of Kansas Health System is just the beginning,” said Jessica Gnad, director of K-State 105. “It’s a way for us to collaborate and to empower Kansans to find local solutions that work in their local community.”

Individuals from K-State and UKHS are putting their heads together to come up with a plan for how this new partnership will work by looking at communities across Kansas.

Through the K-State 105 partnership, K-State and the University of Kansas Health System will work with the statewide K-State Research and Extension network to meaningfully address healthcare challenges, particularly in rural Kansas.

“One of our primary responsibilities is to make sure we take care of Kansans, and we improve the health of Kansans,” said Bob Page, President and CEO of the University of Kansas Health System. “We believe in concert with K-State 105 and in building on the Care Collaborative that we started 10 years ago, this an ideal partnership, for us to be able to deliver that care.”

This program is building off of work done by the Care Collaborative. This health system program serves 73 counties statewide and provides access to the tools, expertise, and resources rural healthcare providers need.

Copyright 2024 WIBW. All rights reserved.

Over 75 firefighters on scene of Jenkin Fire in Pottawatomie, Sunday

Evacuate immediately: RCPD issues evacuation as wildfire swiftly approaches

One home destroyed in Axelton Hill Road fire as multiple agencies continue to battle the blaze

TFD extinguish mulch fires at Topeka Forestry Recycling Center

Three Lawrence city officials receive disturbing notes at their homes, authorities said

Latest news.

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K-State News Kansas State University 128 Dole Hall 1525 Mid-Campus Dr North Manhattan, KS 66506

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K-State doctoral students receive awards for research presentations at Capitol Graduate Research Summit

Friday, March 29, 2024

Two graduate students, Jaymi Peterson and Ramona Weber, were K-State award recipients at the annual Capitol Graduate Research Summit at the State Capitol in Topeka.

MANHATTAN — Two Kansas State University graduate students were recognized for their outstanding research poster presentations at the annual Capitol Graduate Research Summit , or CGRS, held at the State Capitol in Topeka on March 21. Ramona Weber, doctoral student in health and human sciences specializing in kinesiology, Hanover , presented "Effect of dietary nitrate supplementation on tumor oxygenation." Weber's major professor is David Poole, university distinguished professor of kinesiology. Jaymi Peterson, doctoral student in food, nutrition, dietetics and health, Chanute , presented "Effects of pH and wet cooking on sorghum starch digestibility, phenolic profile, and cell bioactivity." Her major professor is Weiqun (George) Wang, professor of food, nutrition, dietetics and health. Both Peterson and Weber received $500 scholarships from the Graduate School for their presentations. The CGRS — coordinated between Kansas' six state universities — is an annual showcase in which graduate students present posters of their research to state legislators and the public to showcase their work and promote the value of graduate education. This year, more than 40 students discussed the implications their work has for issues of interest to Kansas legislators and residents. Outstanding presentations received awards from the participating institutions. Additionally, BioKansas presented three awards. During her presentation, Weber spoke with faculty and graduate students from the University of Kansas Medical Center about the impact of breast cancer, a disease that affects approximately one in eight women. Weber said learning about the research and experiences of graduate students from other departments and universities demonstrated the value of interdisciplinary collaboration. They discussed the dietary aspects of her research, and how it could help improve the chemotherapy process. Prior to the summit, Weber contacted State Rep. Lisa Moser, who represents the 106th District which includes Hanover. Moser visited with Weber at the Capitol and discussed Weber's ongoing research in breast cancer, as well as the impact of breast cancer in rural communities. Weber noted that effective communication of research results, both within the scientific community and the public, is integral to her doctoral training. "There is a significant gap between the public and scientists, which often results in misinformation," she said. "Impactful communication of research can bridge this gap and foster a trusting relationship, enabling continued support for the advancement of science." Peterson also had the opportunity to speak with legislators. She said the process of preparing her research presentation taught her the value of learning to discuss her work in a variety of formats for different audiences, so that it can be relatable to everyone. "One legislator spoke with me in depth," she said. "They were interested to learn about their potential uses for health-foods. When I explained to them that a majority of the public doesn't know what sorghum is or how it could be potentially leveraged for the Kansas economy, the legislators were very interested to learn more." She said the legislators who she spoke with seemed surprised that, according to Peterson's research, cooking food samples for 10 minutes improved starch digestibility. By doing this, the nutritional profile of sorghum for food applications could improve. "They were pleased to learn more about sorghum and how we could use this undervalued cereal grain to better the Kansas economy," Peterson said. "They agreed with me that to better leverage sorghum for Kansas farmers, it is important to first educate the public on sorghum polyphenols and their potential health benefits." Weber and Peterson were two of ten K-State graduate students who presented their research at this year's CGRS were selected to represent K-State based on their presentation at the university's Research and the State poster forum, which took place Oct. 24. They included Savannah Stewart, doctoral student in food science, Valley Center ; Holly Ellis, master's student in architecture, Grimes, Iowa ; Adi Siegmann, master's student in human development and family science-couple and family therapy, Detroit, Michigan ; Andrea Salazar, doctoral student entomology, Ecuador ; Manivannan Selladurai, doctoral student in grain science, India ; Amirsalar Bagheri, doctoral student in chemical engineering, Iran ; Reza Nematirad, doctoral student in electrical and computer engineering, Iran ; and Fidelis Onwuagba, master's student in geology, Nigeria . To learn more about the summit, its participants and their research, visit the Capitol Graduate Research Summit website .

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Sex differences in the role of sleep on cognition in older adults

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Study Objectives: The study aimed to investigate sex differences in the relationship between sleep quality (self-report and objective) and cognitive function across three domains (executive function, verbal memory, and attention) in older adults. Methods: We analyzed cross-sectional data from 207 participants with normal cognition or mild cognitive impairment (89 males and 118 females) aged over 60. The relationship between sleep quality and cognitive performance was estimated using generalized additive models. Objective sleep was measured with the GT9X Link Actigraph, and self-reported sleep was measured with the Pittsburgh Sleep Quality Index. Results: We found that females exhibited stable performance of executive function with up to about 400 minutes of total sleep time, with significant declines in performance (p = 0.02) when total sleep time was longer. Additionally, a longer total sleep time contributed to lower verbal memory in a slightly non-linear manner (p = 0.03). Higher self-reported sleep complaints were associated with poorer executive function in females with normal cognition (p = 0.02). In males, a positive linear relationship emerged between sleep efficiency and executive function (p = 0.04), while self-reported sleep was not associated with cognitive performance in males with normal cognition. Conclusions: Our findings suggest that the relationships between sleep quality and cognition differ between older males and females, with executive function being the most influenced by objective and self-reported sleep. Interventions targeting sleep quality to mitigate cognitive decline in older adults may need to be tailored according to sex, with distinct approaches for males and females.

Competing Interest Statement

CS is the owner and Chief Executive Officer of Sleep Health Education, LLC.

Funding Statement

This study was funded by the University of Kansas Alzheimers Disease Research Center, the National Institute on Aging (grant nos. P30AG035982; R01AG033673), and the University of Kansas General Research Fund.

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Ethics committee/IRB of The University of Kansas Alzheimer's Disease Research Center gave ethical approval for this work.

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

We added exploratory analyses comparing sleep parameters measured by actigraphy and the PSQI. We also compared performed model comparisons to assess which model best explains the relationship between sleep and cognition.

Data Availability

The dataset presented in this article is not readily available because dataset requests must be made directly to the KU-ADRC. Those interested in accessing the dataset should be directed to the following website where they can complete a data request form: https://www.kumc.edu/research/alzheimers-disease-research-center/research/resources-for-researchers-and-principal-investigators.html.

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Dr. Mark Clements Receives JDRF Award to Study Psychosocial Technology for Youth with Type 1 Diabetes

April 03, 2024.

Mark A. Clements, MD, PhD

Rick & cathy baier family endowed chair in endocrinology; medical director, pediatric clinical research unit; professor of pediatrics, university of missouri-kansas city school of medicine; clinical assistant professor of pediatrics, university of kansas school of medicine.

Mark Clements, MD, PhD , Endocrinology , received a two-year, $710,434.16 award from JDRF International for his project, “Spotlight-AQ 2 Center RCT,” to study whether the use of Spotlight-AQ, a biopsychosocial pre-visit planning technology, will benefit adolescents and young adults with type 1 diabetes (T1D).

Dealing with T1D can cause psychosocial burdens (depression, diabetes distress, anxiety, fear of hypoglycemia, family conflict) in adolescent and young adults. If not addressed, these issues can result in negative outcomes for individuals with T1D. Routine clinical visits often focus on biomedical outcomes and disease management, and it can be difficult for health care providers to provide tailored support for psychosocial-related issues.

“While we have made some progress in assessing psychosocial concerns during our pre-visit planning process, the approach offered by the Spotlight AQ tool has the potential to accelerate our progress in this important area,” said Dr. Clements.

Data from Spotlight-AQ studies in adults with T1D indicate the use of the technology had positive outcomes for participants. Dr. Clements will study whether adolescents and young adults with T1D could also benefit from a youth- and young adult-focused version of the technology. His team will collect initial data on the acceptability, feasibility, and effectiveness of Spotlight-AQ in this population. The team will use Spotlight-AQ to identify patient-defined needs to guide topics discussed in two, regularly scheduled clinic visits. His team will measure:

• Acceptability to youth/young adults with T1D, their parents and providers
• Feasibility (completion rate for all components)
• Effectiveness (glycemic control, psychosocial outcomes, and engagement with self-management)

Spotlight-AQ was co-designed by persons with T1D and applies a biopsychosocial theoretical model of care. It includes electronic assessments for the person with diabetes to complete and a clinician toolkit on how to respond at the point of care to identified needs. Previous research has shown that the most common patient priorities are knowledge gaps and psychological burden. Often, it is possible for clinicians to address these issues in routine care. By applying an evidence-based and patient-centered approach to pre-visit planning, Spotlight AQ reduces the chances of problems persisting or worsening and requiring professional psychology support.

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Florida State University

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Fsu researcher: digital tools including ai alter consumer trust, purchasing decisions.

Colleen Harmeling, FSU’s Dr. Persis E. Rockwood Associate Professor of Marketing, points to photo filters, overly edited photos and other distortions of user-generated content as impediments to consumer trust. Harmeling credits a new study on the topic largely to University of Missouri-Kansas City assistant professor Rachel Hochstein, who studied under Harmeling as a marketing Ph.D. student at FSU before landing her faculty post.   Photo by Kallen M. Lunt/College of Business Click to enlarge

Consumers who rely on blog posts, online reviews, testimonials and other user-generated content to inform their purchase decisions require digital platforms that minimize suspicion of missing or misrepresented content.

So says Colleen Harmeling , a Florida State University College of Business researcher who points to photo filters, overly edited photos and other distortions of user-generated content as impediments to consumer trust and, in turn, as potential barriers to the performance of products that users present and discuss in online platforms.

“Availability of certain features, including photo filters or the ability to delete content once you’ve posted it, dramatically impacts whether user-generated content affects brand performance or firm performance,” says Harmeling, FSU’s Dr. Persis E. Rockwood Associate Professor of Marketing and the co-director of the Ph.D. program’s major in marketing. “Those features don’t even have to be used to affect product performance. The mere presence of such features in a digital space affects consumer trust in that content for their purchase decision.”

Harmeling’s new study with Rachel Hochstein , an assistant professor of marketing at the University of Missouri-Kansas City, and Taylor Perko , who served as an FSU research assistant while earning her MBA from the College of Business, appears in the Journal of the Academy of Marketing Science . 

The authors assert in their study that their findings reinforce the notion that digital platforms “serve as custodians of trust in modern society.” 

Harmeling credits the study largely to Hochstein, who studied under Harmeling as a marketing Ph.D. student at FSU before landing her faculty post. Hochstein compiled a database of nearly 20 years of digital platform innovations, recording the timing of changes in user features such as photo filters across online platforms, including Facebook, Amazon and Twitter, now known as X. She combined the database with data, through a so-called meta-analysis, from 77 published studies on the effects of consumer-generated content on company performance. 

Harmeling called it “a very significant study” that “I think has profound implications for how and what we trust as consumers, for how marketers engage with their consumers and how to increase the trustworthiness of the information that's being circulated about the brand.” 

'Helping consumers make these judgments should be a priority of marketers, because suspicion of even single posts can erode trust in the entire body of user-generated content and sow uncertainty in consumers’ purchase decisions.' 

“We’re very proud of Colleen, Rachel and Taylor’s work to develop strategies that promote trust and offset consumers’ concerns in a setting where it’s needed most,” said Michael Brady , director of Dr. Persis E. Rockwood School of Marketing and the Bob Sasser Professor of Marketing in the FSU College of Business. “Their study exemplifies our world-renowned faculty’s cutting-edge research, which asks crucial questions and seeks achievable solutions for the benefit of students, consumers and industries.”

The results showed ways in which those features influenced trust, distrust and purchasing decisions, the researchers said

“We found that trust can be violated if people believed that that their digitally presented content wasn't what unfolded in reality – that's where the photo filters come into play – or if there was missing data from their observable example,” Harmeling said. “If we suspect missing data, then we start to call into question whether the online user’s experience with a product is reflective of the population.

The researchers wrote that their findings also carry implications for social media influencers, who they say might want to avoid use of, for example, photo filters or overly edited photos and videos. “Focusing instead on live videos or real-time ‘story’ posts may be perceived as more trustworthy,” they wrote.

More importantly, the researchers urged marketers to help consumers distinguish “real versus fake or missing versus complete content.” Such judgments “require the ability to identify patterns in a body of user-generated content, recognize anomalies in the pattern and estimate the impact of truth-altering features on each online platform,” they wrote.

They added: “Helping consumers make these judgments should be a priority of marketers, because suspicion of even single posts can erode trust in the entire body of user-generated content and sow uncertainty in consumers’ purchase decisions.” 

Harmeling also emphasized policy implications, especially amid the rapid proliferation of artificial intelligence. The European Union’s AI Act, scheduled to take effect this year, will require labeling of deepfake  AI-generated photos, video or audio of existing people and places as artificially manipulated.

“We think of photo filtering as one of the first movers in AI, changing reality to something that’s slightly enhanced,” Harmeling said. “Now we have AI that’s much more advanced – replicating people’s voices, for example. I think there are numerous implications for this research and for further research down this path.”

-- Pete Reinwald

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