Analytical Research Laboratories

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2225 W Alice Ave

Phoenix, AZ 85021

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This program probably saved my life. I believe in what they're doing and I find them totally honest and ethical. As a practitioner, I continue to use their services over 30 years.

Their program saved my life. Excellent!

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they do not know what they are doing! beware. they contradict themselves and are poorly run and unethical. their knowledge and accuracy are bad. also, they are very money hungry, charging the consumer 4 times as much or more then the cost.

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hairanalysisreport.com

HairAnalysisReport.com

Using Hair Analysis to Improve Health Through Nutrition!

Analytical Research Labs Inc. | Profile II

Analytical research labs inc. profile ii – hair analysis.

Our ARL Profile II hair analysis is your initial analysis that provides important information needed for comprehensive nutrition specific to your current metabolic needs.

Our Profile II Hair Analysis by Analytical Research Labs Inc. includes:

Arl Hair Mineral Analysis, Hairanalysisreport.com

  • A comprehensive interpretation, in layman terms, (usually 26 pages)
  • Stage of stress
  • Organs and systems patterns
  • Metabolic patterns and trends
  • Electrolyte patterns
  • Digestion patterns
  • Recommendations for foods and supplements
  • Program support – Includes complementary phone Consultation (up to 1-hour) to review results and includes any additional questions while following the program

Note: Supplements from Endo-met Laboratories (ARL) are purchased separately. Tests not available to New York residents. For accuracy, we prefer untreated scalp hair. See  FAQ’s .

Profile II – Hair Analysis by Analytical Research Labs Inc. Only $174.00   (U.S. only – NO International Orders!)

Order Your ARL Hair Analysis Today!

Turnaround Time: averages 18-21 days

Commonly tested elements:

Nutritional Elements: Calcium, Magnesium, Sodium, Potassium, Iron, Copper, Manganese, Zinc, Chromium, Selenium, Phosphorus

Toxic Elements:  Arsenic, Mercury, Cadmium, Lead, Aluminum

Additional Elements: Cobalt, Molybdenum, Lithium, Nickel

Significant Mineral Ratios: Calcium/Magnesium, Calcium/Potassium, Sodium/Magnesium, Sodium/Potassium, Zinc/Copper, Calcium/Phosphorous

View a Sample Report from Analytical Research Labs Inc.

The content and laboratory services provided on this site are for educational and informational purposes only and not intended to diagnose, treat, prevent, or cure disease.

analytical research labs reviews

Hair Analysis: Why We Use Analytical Research Labs

Posted by Eileen Durfee on 22nd Mar 2015

Get your  Hair Analysis test and Nutritional Balancing program to determine the toxic metals and mineral imbalances in your body! This will help guide a corrective program customized to enhance your health. This is the most affordable and reliable method for precise results that will lead the way to a healthier life.  All of the Hair Analysis tests purchased through us are processed by  Analytical Research Labs and reviewed by  Dr. Lawrence Wilson . 

Why we recommend Analytical Research Labs

There are several factors that contribute to why Analytical Research Labs is the most  recommended for processing Hair Analysis tests:

  • They do not wash the hair samples at the lab

For the most complete analysis, it is necessary that the hair  is not washed in the lab before testing. The results can vary when the washing agents and chemicals remove natural minerals from the hair. 

  • Dr. Eck’s ideal ratios and levels are used

Analytical Research Labs provides a full Hair Analysis test interpretation based on Dr. Paul Eck's methods. This includes information about energy levels, carbohydrate tolerance, autonomic balance, metabolic trends, diet guidelines, metabolic rate, sugar tolerance, immune system, glandular activity, and a customized supplement program.

  • Personalized Dr. Wilson program

All Hair Analysis tests processed with Analytical Research Labs include a Dr. Wilson created and customized program based on your personal lifestyle and diet to provide the most successful and accurate outcome.

analytical research labs reviews

A criticism may be made that other research labs point out more toxic elements than Analytical Research Labs. However, ARL does not review more toxic metals than are necessary to help create a corrective program. They analyze and report only the essential information in order to keep the costs low and lead the way with the most accurate Nutritional Balancing Science program possible.

Purchase your Hair Analysis test from Wellness Shopping Online today for the best results and a personalized plan to help improve your health and future!

This material is for educational purposes only The preceding statements have not been evaluated by the Food and Drug Administration This information is not intended to diagnose, treat, cure or prevent any disease.

  • #Dr. Lawrence Wilson
  • #Dr. Wilson and associates
  • #Hair Analysis
  • #Hair Analysis kit
  • #Hair Analysis lab report
  • #Nutritional Balancing Science
  • #www.drlwilson.com

analytical research labs reviews

ARL is an Authority on Nutrition and the Science of Balancing Body Chemistry Through Hair Tissue Mineral Analysis!

The Validity of Hair Analysis

Home » Newsletters » The Validity of Hair Analysis

Clients and other health professionals at times ask for proof of the validity of hair mineral test­ing. There are at least three issues to consider: the validity of the testing procedure, the significance of the results and the validity of supplement programs based upon the readings.

Validity Of Mineral Testing

Spectrographic analysis is the standard method used for determining the mineral content of soil, rocks, tissue samples and other mineral-contain­ing materials. Anyone knowledgeable in chemical analysis is aware this technique is used at every university and in thousands of private laboratories across the nation.

Tissue mineral analysis is performed at Ana­lytical Research Labs (a.k.a. Accutrace Labs) via a computer-controlled inductively coupled plasma (ICP) instrument. This is a standard testing instru­ment used throughout the world.

Accutrace replaced their Perkin Elmer Elan 9000 ICP Mass Spectrometer with the Perkin Elmer NexION 2000 ICP-MS. ICP instrumentation is faster and can analyze more minerals. Accutrace Laboratories is licensed by the federal government and is inspected annually. Blind samples must be submitted that are within standard limits.

Accuracy also depends upon careful attention to the testing procedure and the kind of controls that are run with each batch of samples. Control samples are test samples in which the values are known in advance.

At Accutrace Labs, three sets of controls are run at the beginning and end of every batch of samples, every day. If any of the readings of the controls are not within strict guidelines, the entire batch of results is discarded. The instrument is recalibrated and the batch is rerun. We know of very few laboratories that go to this much trouble to make sure every reading is accurate.

Hair Analysis Studies

One study in the Journal of the AMA , August 23/30, 1985, Vol. 254, #8, pp 1041-1045 ques­tioned the validity of the testing procedure for hair analysis. Supposedly, similar samples were sent to 13 laboratories. Results varied between several of the laboratories. On this basis, the author felt that hair analysis was a "fraud".

  • Long hair was cut up and mixed by hand for the samples. Mechanical mixing of hair sam­ples to produce a homogenous sample is very difficult, if not impossible.
  • After cutting, hair was washed under the tap before being cut up. This is a violation of sampling protocol. Hair should not be washed at home after being cut and especially not in tap water.
  • Some hair analysis laboratories wash the samples in various chemicals including water, detergents and acetone for varying lengths of time. This creates some variations in the readings. These differences were ignored in the study. We do not wash the sample before testing.

Any one of these problems would discredit the study. Together they make it basically useless.

For those who like scientific studies, however, the U.S. Environmental Protection Agency reviewed over 400 studies of hair analysis in 1979. The reviews involved mainly toxic metals. The EPA concluded that "hair is a meaningful and representative tissue for biological monitoring for most of the toxic metals." This 300-page docu­ment is entitled Toxic Trace Metals in Mam­malian Hair and Nails , EPA-600 4.79-049, August 1979.

Significance Of The Readings

What do hair analysis readings mean? This is a more difficult question. Our test interpretation is based upon original research by Dr. Paul Eck.

Dr. Eck synthesized many modern biological concepts to arrive at his interpretation methods. These include general systems theory, retracing theory, theory of biological transmutation (Louis Kervan), biochemical individuality (Roger Williams), the oxidation types (Dr. George Watson), the stages of stress (Dr. Hans Selye) and the mineral system (William Albrecht).

There have been a few scientific studies of hair analysis interpretation. One article appeared in the Journal of Orthomolecular Medicine , Vol. 1, #2, 1986. This article compared physical signs and symptoms in a group of patients with their oxidation type according to a hair analysis. The study found good, though not perfect correlation. This same journal is a good source for other hair analysis studies.

Regarding the significance of the readings, the best answer is the concepts and principles of interpretation we use correlate well with physical signs and symptoms. They allow us to predict symptoms accurately and are certainly subject to refinement by future researchers. This is the nature of scientific research.

Diet And Supplement Programs Based Upon Hair Analysis

It is one thing to interpret a hair test. It is another thing to offer a protocol for correction of imbalances. This area is even more empirical. Dr. Eck based his work on that of many other clini­cians, including Dr. George Watson, Dr. Carl Pfeiffer, MD PhD and many others who spent years designing clinical regimens to correct body chemistry. Quantities of foods, dosages of supplements, frequency of dosages and other factors are all empirical and individual in nature. The only proof of the validity of any such regimen is its effectiveness.

In summary, there is no question about the validity of hair mineral testing. The interpretation method is rather complex. We can say that the program has helped thousands of people. Ulti­mately, you must experience the program for yourself to determine its validity for you.

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  • News & Analysis on Clinical Trial Services & Contract Research And Development

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Could AI signal the end of the use of lab rats in research? Olden Labs reveals all

29-Apr-2024 - Last updated on 29-Apr-2024 at 11:23 GMT

  • Email to a friend

© Olden Labs

Using artificial intelligence (AI), genetic engineering, and robotics, the company said it proudly introduces the world’s first automated animal research lab.

Founded by a team of experts spanning diverse disciplines, including a Harvard PhD biologist, a Forbes 30 Under 30 AI developer, and engineers from 10X Genomics and Apple, Olden Labs stands backed by supporters such as CHMBR Partners, Healthspan Capital, and the Mercatus Center’s Emergent Ventures.

“Animal research has been a cornerstone of therapy development, yet it has seen limited innovation,” remarks Michael Florea, co-founder, and CEO of Olden Labs.

“Many current methods are relics of the 1960s, while biologists revel in terabytes of digital data, animal studies remain entrenched in manual processes, often relegating results to paper. It became evident that bridging this technology gap could yield profound societal benefits.”

Animal testing ineffective and costly

Olden’s emergence aligns with a pivotal moment in legislative history, where a new US law eliminates the requirement for drugs in development to undergo testing in animals before human trials. Advocates for animal rights have long championed such a move, arguing that animal testing can be both ineffective and costly.

Dating back to the 18th century, laboratory rats have played a pivotal role in scientific research, from studies on digestion to advancements in physiology, pharmacology, and toxicology.

This legislative shift comes at a time when over $36 billion is annually allocated to animal studies, yet a staggering 90.4% of new drugs fail in human clinical trials. The archaic nature of animal research, characterized by high costs, low reproducibility, and poor data quality, necessitates a paradigm shift.

Real-time monitoring of animal health and behavior

Olden Labs, with its trifecta of innovative technologies encompassing robotics, AI, and gene delivery, aims to revolutionize animal studies. Their pioneering product, DOME smart cages, equipped with AI capabilities, offers real-time monitoring of animal health and behavior, providing researchers with a comprehensive understanding of their subjects' well-being.

“Labs across the U.S. utilize 111 million rodents annually, with upkeep costs exceeding $16 billion,” explains Charles Hirschler, managing member of CHMBR Partners, L.P., Olden Labs’ lead seed investor.

“Having experienced firsthand the challenges of traditional animal research, coupled with the rapid advancements in AI, robotics, and data acquisition, Olden Labs presents a unique opportunity to address these pressing needs.”

Voices as well as Olden Labe within the pharmaceutical sector have echoed these sentiments, highlighting the shortcomings of animal testing.

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analytical research labs reviews

Challenges faced with 3D-printed electrochemical sensors in analytical applications

  • Critical Review
  • Published: 26 April 2024

Cite this article

analytical research labs reviews

  • Lauro A. Pradela‑Filho 1 ,
  • Diele A. G. Araújo 1 ,
  • Vanessa N. Ataide 1 ,
  • Gabriel N. Meloni 1 &
  • Thiago R. L. C. Paixão 1  

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Prototyping analytical devices with three-dimensional (3D) printing techniques is becoming common in research laboratories. The attractiveness is associated with printers’ price reduction and the possibility of creating customized objects that could form complete analytical systems. Even though 3D printing enables the rapid fabrication of electrochemical sensors, its wider adoption by research laboratories is hindered by the lack of reference material and the high “entry barrier” to the field, manifested by the need to learn how to use 3D design software and operate the printers. This review article provides insights into fused deposition modeling 3D printing, discussing key challenges in producing electrochemical sensors using currently available extrusion tools, which include desktop 3D printers and 3D printing pens. Further, we discuss the electrode processing steps, including designing, printing conditions, and post-treatment steps. Finally, this work shed some light on the current applications of such electrochemical devices that can be a reference material for new research involving 3D printing.

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analytical research labs reviews

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analytical research labs reviews

Reproduced from Stefano et al. [ 17 ]

analytical research labs reviews

Adapted from Shergill and Patel [ 29 ]. B Electrode orientated vertically on the printed platform to increase the conductivity of back-contacted electrodes. Adapted from Hamzah et al. [ 32 ]. C Different infill patterns used to print solid electrodes. Adapted from Bernalte et al. [ 30 ]

analytical research labs reviews

Adapted from Kalinke et al. [ 26 ]. B Manufacture of lab-made conductive filaments using graphite and ABS for printing 3D electrodes. Reproduced from Petroni et al. [ 15 ]. C Production of lab-made recycled conductive and non-conductive filaments for electroanalysis. Reproduced from Crapnell et al. [ 45 ]

analytical research labs reviews

Adapted from Silveira et al. [ 52 ]. B The electrochemical cell (transversal cut view) is used for batch and flow electroanalysis. Reproduced from Cardoso et al. [ 8 ]. C 3D-printed cassette-based integrated into an electrochemical-aptasensor for detecting dengue virus. Reproduced from Mohd et al. [ 53 ]. D 3D robotic system for ion-selective sensing. Reproduced from Ozer et al. [ 54 ]

analytical research labs reviews

Reproduced from Hamzah et al. [ 58 ]. B Scheme that represents an alternative to modifying the 3D-printed electrodes on the printing table. Reproduced from Hérnandez-Rodríguez et al. [ 59 ]. C The 3D-printed electrochemical ring (e-ring) for glucose sensing. Reproduced from Katseli [ 60 ]

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analytical research labs reviews

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Additive manufacturing by digital light processing: a review

analytical research labs reviews

A 3D printed acoustofluidic nozzle-diffuser microfluidic pump

Veloso WB, Paixão TRLC, Meloni GN. 3D printed electrodes design and voltammetric response. Electrochim Acta. 2023;449: 142166. https://doi.org/10.1016/J.ELECTACTA.2023.142166 .

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Ambrosi A, Pumera M. 3D-printing technologies for electrochemical applications. Chem Soc Rev. 2016;45:2740–55. https://doi.org/10.1039/C5CS00714C .

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Sharma A, Faber H, Khosla A, Anthopoulos TD. 3D printed electrochemical devices for bio-chemical sensing: a review. Mater Sci Eng R Rep. 2023;156: 100754. https://doi.org/10.1016/J.MSER.2023.100754 .

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Pradela-Filho LA, Veloso WB, Medeiros DN, Lins RSO, Ferreira B, Bertotti M, Paixão TRLC. Patterning (electro)chemical treatment-free electrodes with a 3D printing pen. Anal Chem. 2023;95:10634–43. https://doi.org/10.1021/acs.analchem.3c01084 .

Pradela Filho LA, Paixão TRLC, Nordin GP, Woolley AT. Leveraging the third dimension in microfluidic devices using 3D printing: no longer just scratching the surface. Anal Bioanal Chem. 2023. https://doi.org/10.1007/s00216-023-04862-w .

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Singh Shergill R, Anil Patel B. Preprinting saponification of carbon thermoplastic filaments provides ready-to-use electrochemical sensors. ACS Appl Electron Mater. 2023;5:5120–8. https://doi.org/10.1021/acsaelm.3c00862 .

Manzanares Palenzuela CL, Novotný F, Krupička P, Sofer Z, Pumera M. 3D-printed graphene/polylactic acid electrodes promise high sensitivity in electroanalysis. Anal Chem. 2018;90:5753–7. https://doi.org/10.1021/acs.analchem.8b00083 .

Cardoso RM, Mendonça DMH, Silva WP, Silva MNT, Nossol E, da Silva RAB, Richter EM, Muñoz RAA. 3D printing for electroanalysis: from multiuse electrochemical cells to sensors. Anal Chim Acta. 2018;1033:49–57. https://doi.org/10.1016/j.aca.2018.06.021 .

Katic V, Dos Santos PL, Dos Santos MF, Pires BM, Loureiro HC, Lima AP, Queiroz JCM, Landers R, Muñoz RAA, Bonacin JA. 3D printed graphene electrodes modified with Prussian blue: emerging electrochemical sensing platform for peroxide detection. ACS Appl Mater Interfaces. 2019;11:35068–78. https://doi.org/10.1021/acsami.9b09305 .

Abdalla A, Patel BA. 3D printed electrochemical sensors. Annu Rev Anal Chem. 2021;14:47–63. https://doi.org/10.1146/annurev-anchem-091120-093659 .

de Matos Morawski F, Martins G, Ramos MK, Zarbin AJG, Blanes L, Bergamini MF, Marcolino-Junior LH. A versatile 3D printed multi-electrode cell for determination of three COVID-19 biomarkers. Anal Chim Acta. 2023;1258. https://doi.org/10.1016/j.aca.2023.341169

Sigley E, Kalinke C, Crapnell RD, Whittingham JM, Williams RJ, Keefe EM, Campos Janegitz B, Alves Bonacin J, Banks CE. Circular economy electrochemistry: creating additive manufacturing feedstocks for caffeine detection from post-industrial coffee pod waste. ACS Sustain Chem Eng. 2023;11:2978–88. https://doi.org/10.1021/acssuschemeng.2c06514 .

Article   CAS   PubMed   PubMed Central   Google Scholar  

Saggiomo V. A 3D printer in the lab: not only a toy. Adv Sci. 2022;9:1–8. https://doi.org/10.1002/advs.202202610 .

UltiMaker S7 3D Printer. https://store.makerbot.com/3d-printers/s-series-3d-printers/ultimaker-s7-3d-printer . Accessed 10 March 2024

Petroni JM, Neves MM, de Moraes NC, Bezerra da Silva RA, Ferreira VS, Lucca BG. Development of highly sensitive electrochemical sensor using new graphite/acrylonitrile butadiene styrene conductive composite and 3D printing-based alternative fabrication protocol. Anal Chim Acta. 2021;1167. https://doi.org/10.1016/j.aca.2021.338566

Tully JJ, Meloni GN. A scientist’s guide to buying a 3D printer: how to choose the right printer for your laboratory. Anal Chem. 2020;92:14853–60. https://doi.org/10.1021/acs.analchem.0c03299 .

Stefano JS, Guterres e Silva LR, Rocha RG, Brazaca LC, Richter EM, Abarza Muñoz RA, Janegitz BC. New conductive filament ready-to-use for 3D-printing electrochemical (bio)sensors: towards the detection of SARS-CoV-2. Anal Chim Acta. 2021;1191:339372. https://doi.org/10.1016/j.aca.2021.339372 .

Foster CW, Elbardisy HM, Down MP, Keefe EM, Smith GC, Banks CE. Additively manufactured graphitic electrochemical sensing platforms. Chem Eng J. 2020;381: 122343. https://doi.org/10.1016/J.CEJ.2019.122343 .

Cruz MA, Ye S, Kim MJ, Reyes C, Yang F, Flowers PF, Wiley BJ. Multigram synthesis of Cu-Ag core–shell nanowires enables the production of a highly conductive polymer filament for 3D printing electronics. Part Part Syst Charact. 2018;35:1700385. https://doi.org/10.1002/ppsc.201700385 .

Stefano JS, Kalinke C, Da Rocha RG, Rocha DP, Da Silva VAOP, Bonacin JA, Angnes L, Richter EM, Janegitz BC, Muñoz RAA. Electrochemical (bio)sensors enabled by fused deposition modeling-based 3D Printing: a guide to selecting designs, printing parameters, and post-treatment protocols. Anal Chem. 2022;94:6417–29. https://doi.org/10.1021/acs.analchem.1c05523 .

Crapnell RD, Kalinke C, Silva LRG, Stefano JS, Williams RJ, Abarza Munoz RA, Bonacin JA, Janegitz BC, Banks CE. Additive manufacturing electrochemistry: an overview of producing bespoke conductive additive manufacturing filaments. Mater Today. 2023;71:73–90. https://doi.org/10.1016/J.MATTOD.2023.11.002 .

Silva-Neto HA, Duarte-Junior GF, Rocha DS, Bedioui F, Varenne A, Coltro WKT. Recycling 3D printed residues for the development of disposable paper-based electrochemical sensors. ACS Appl Mater Interfaces. 2023. https://doi.org/10.1021/acsami.3c00370 .

Arantes IVS, Crapnell RD, Whittingham JM, Sigley E, Paixão TRLC, Banks CE. Additive manufacturing of a portable electrochemical sensor with a recycled conductive filament for the detection of atropine in spiked drink samples. ACS Appl Eng Mater. 2023;1:2397–406. https://doi.org/10.1021/acsaenm.3c00345 .

Crapnell RD, Arantes IVS, Camargo JR, Bernalte E, Whittingham MJ, Janegitz BC, Paixão TRLC, Banks CE. Multi-walled carbon nanotubes/carbon black/rPLA for high-performance conductive additive manufacturing filament and the simultaneous detection of acetaminophen and phenylephrine. Microchim Acta. 2024;191:96. https://doi.org/10.1007/s00604-023-06175-2 .

Meloni GN, Bertotti M. 3D printing scanning electron microscopy sample holders: a quick and cost effective alternative for custom holder fabrication. PLoS ONE. 2017;12: e0182000. https://doi.org/10.1371/journal.pone.0182000 .

Kalinke C, Neumsteir NV, Aparecido GDO, Ferraz TVDB, Dos Santos PL, Janegitz BC, Bonacin JA. Comparison of activation processes for 3D printed PLA-graphene electrodes: electrochemical properties and application for sensing of dopamine. Analyst. 2020;145:1207–18. https://doi.org/10.1039/c9an01926j .

Torres LM, Gil AF, Galicia L, González I. Understanding the difference between inner- and outer-sphere mechanisms: an electrochemical experiment. J Chem Educ. 1996;73:808. https://doi.org/10.1021/ed073p808 .

Crapnell RD, Garcia-Miranda Ferrari A, Whittingham MJ, Sigley E, Hurst NJ, Keefe EM, Banks CE. Adjusting the connection length of additively manufactured electrodes changes the electrochemical and electroanalytical performance. Sensors. 2022;22:9521. https://doi.org/10.3390/s22239521 .

Shergill RS, Patel BA. The effects of material extrusion printing speed on the electrochemical activity of carbon black/polylactic acid electrodes**. ChemElectroChem. 2022;9:1–8. https://doi.org/10.1002/celc.202200831 .

Bernalte E, Crapnell RD, Messai OMA, Banks CE. The effect of slicer infill pattern on the electrochemical performance of additively manufactured electrodes. Chem Electro Chem. 2024;1–10. https://doi.org/10.1002/celc.202300576

Kalinke C, Crapnell RD, Sigley E, Whittingham MJ, de Oliveira PR, Brazaca LC, Janegitz BC, Bonacin JA, Banks CE. Recycled additive manufacturing feedstocks with carboxylated multi-walled carbon nanotubes toward the detection of yellow fever virus cDNA. Chem Eng J. 2023;467: 143513. https://doi.org/10.1016/j.cej.2023.143513 .

Bin Hamzah HH, Keattch O, Covill D, Patel BA. The effects of printing orientation on the electrochemical behaviour of 3D printed acrylonitrile butadiene styrene (ABS)/carbon black electrodes. Sci Rep. 2018;8:9135. https://doi.org/10.1038/s41598-018-27188-5 .

Browne MP, Novotný F, Sofer Z, Pumera M. 3D printed graphene electrodes’ electrochemical activation. ACS Appl Mater Interfaces. 2018;10:40294–301. https://doi.org/10.1021/acsami.8b14701 .

Cardoso RM, Castro SVF, Silva MNT, Lima AP, Santana MHP, Nossol E, Silva RAB, Richter EM, Paixão TRLC, Muñoz RAA. 3D-printed flexible device combining sampling and detection of explosives. Sens Actuators B Chem. 2019;292:308–13. https://doi.org/10.1016/j.snb.2019.04.126 .

Singh Shergill R, Perez F, Abdalla A, Anil Patel B. Comparing electrochemical pre-treated 3D printed native and mechanically polished electrode surfaces for analytical sensing. J Electroanal Chem. 2022;905. https://doi.org/10.1016/j.jelechem.2021.115994

Vaněčková E, Bouša M, Nováková Lachmanová Š, Rathouský J, Gál M, Sebechlebská T, Kolivoška V. 3D printed polylactic acid/carbon black electrodes with nearly ideal electrochemical behaviour. J Electroanal Chem. 2020;857: 113745. https://doi.org/10.1016/J.JELECHEM.2019.113745 .

Gusmão R, Browne MP, Sofer Z, Pumera M. The capacitance and electron transfer of 3D-printed graphene electrodes are dramatically influenced by the type of solvent used for pre-treatment. Electrochem Commun. 2019;102:83–8. https://doi.org/10.1016/j.elecom.2019.04.004 .

Redondo E, Muñoz J, Pumera M. Green activation using reducing agents of carbon-based 3D printed electrodes: turning good electrodes to great. Carbon N Y. 2021;175:413–9. https://doi.org/10.1016/j.carbon.2021.01.107 .

Richter EM, Rocha DP, Cardoso RM, Keefe EM, Foster CW, Munoz RAA, Banks CE. Complete additively manufactured (3D-printed) electrochemical sensing platform. Anal Chem. 2019;91:12844–51. https://doi.org/10.1021/acs.analchem.9b02573 .

Wirth DM, Sheaff MJ, Waldman JV, Symcox MP, Whitehead HD, Sharp JD, Doerfler JR, Lamar AA, Leblanc G. Electrolysis activation of fused-filament-fabrication 3D-printed electrodes for electrochemical and spectroelectrochemical analysis. Anal Chem. 2019;91:5553–7. https://doi.org/10.1021/acs.analchem.9b01331 .

dos Santos PL, Katic V, Loureiro HC, dos Santos MF, dos Santos DP, Formiga ALB, Bonacin JA. Enhanced performance of 3D printed graphene electrodes after electrochemical pre-treatment: role of exposed graphene sheets. Sens Actuators B Chem. 2019;281:837–48. https://doi.org/10.1016/j.snb.2018.11.013 .

Rocha DP, Ataide VN, de Siervo A, Gonçalves JM, Muñoz RAA, Paixão TRLC, Angnes L. Reagentless and sub-minute laser-scribing treatment to produce enhanced disposable electrochemical sensors via additive manufacture. Chem Eng J. 2021;425:1–12. https://doi.org/10.1016/j.cej.2021.130594 .

Pereira JFS, Rocha RG, Castro SVF, João AF, Borges PHS, Rocha DP, de Siervo A, Richter EM, Nossol E, Gelamo RV, Muñoz RAA. Reactive oxygen plasma treatment of 3D-printed carbon electrodes towards high-performance electrochemical sensors. Sens Actuators B Chem. 2021;347. https://doi.org/10.1016/j.snb.2021.130651

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This study is financially supported by the São Paulo Research Foundation—FAPESP (Grant numbers: 2018/08782-1, 2021/00205-8, 2022/11346-4, and 2023/01723-8), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) – (Grant numbers: 405620/2021-7 and 302839/2020-8), and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001.

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Lauro A. Pradela‑Filho, Diele A. G. Araújo, Vanessa N. Ataide, Gabriel N. Meloni & Thiago R. L. C. Paixão

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Lauro A. Pradela‑Filho: conceptualization; writing, original draft preparation; writing, review and editing. Diele A.G. Araújo: writing, original draft preparation; writing, review and editing. Vanessa N. Ataide: writing, original draft preparation; writing, review and editing. Gabriel N. Meloni: writing, original draft preparation; writing, review and editing. Thiago R.L.C. Paixão: writing, review and editing; funding acquisition; supervision. All authors read and approved the final manuscript.

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Pradela‑Filho, L.A., Araújo, D.A.G., Ataide, V.N. et al. Challenges faced with 3D-printed electrochemical sensors in analytical applications. Anal Bioanal Chem (2024). https://doi.org/10.1007/s00216-024-05308-7

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