diabetes research paper pdf

This high blood sugar often causes nerve damage, kidney damage, eye damage, heart disease, skin hearing impairment, etc. Loss of limb, blindness is also some of the effects [3]. ... An Approach ...

Supplementary Appendix (nejmsa2032271_appendix.pdf) Download; 223.08 KB; Disclosure Forms (nejmsa2032271_disclosures.pdf) ... Chronicle of Diabetes Research and Practice, 3, 1, ...

Global report on diabetes is a comprehensive document that provides the latest data and analysis on the global burden, prevention and management of diabetes. It highlights the need for urgent action to reduce the impact of diabetes on individuals, health systems and economies. The report also offers evidence-based recommendations and best practices for preventing and treating diabetes and its ...

I. Introduction. Diabetes mellitus, a metabolic disease defined by elevated fasting blood glucose levels due to insufficient insulin production, has reached epidemic proportions worldwide (World Health Organization, 2020).Type 1 and type 2 diabetes (T1D and T2D, respectively) make up the majority of diabetes cases with T1D characterized by autoimmune destruction of the insulin-producing ...

The best evidence for a link between diabetes mellitus and breast cancer comes from a systematic review of six prospective cohort studies and more than 150,000 women, in which the hazard ratio (HR ...

Table 7 Assessment of effectiveness of diabetes services 27 Table 8 Stratification of level of risk of developing diabetic foot problems or the need for an amputation 33 Figures Fig. 1 Protocol for control of blood glucose in type 2 diabetes* 16 Fig. 2 Type 2 diabetes management protocol derived from WHO-PEN 25 Fig. 3 Examples of foot ulcers 30

Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes worldwide. The number afected is increasing rapidly with alarming trends in children and young adults (up to age 40 years). Early detection and proactive management are crucial for prevention and mitigation of microvascular and macrovascular complications ...

The chronic complications of type 2 diabetes are a major cause of mortality and disability worldwide [ 1, 2 ]. Clinical research is the main way to gain knowledge about long-term diabetic complications and reduce the burden of diabetes. This allows for designing effective programs for screening and follow-up and fine-targeted therapeutic ...

Introduction. Diabetes mellitus (DM) is probably one of the oldest diseases known to man. It was first reported in Egyptian manuscript about 3000 years ago. 1 In 1936, the distinction between type 1 and type 2 DM was clearly made. 2 Type 2 DM was first described as a component of metabolic syndrome in 1988. 3 Type 2 DM (formerly known as non-insulin dependent DM) is the most common form of DM ...

New estimates published this week in The Lancet indicate that more than 1·31 billion people could be living with diabetes by 2050 worldwide. That's 1·31 billion people living with a disease that causes life-altering morbidity, high rates of mortality, and interacts with and exacerbates many other diseases. The increase in prevalence (up from 529 million in 2021) is expected to be driven by ...

Diabetes mellitus (DM) underscores a rising epidemic orchestrating critical socio-economic burden on countries globally. Different treatment options for the management of DM are evolving rapidly because the usual methods of treatment have not completely tackled the primary causes of the disease and are laden with critical adverse effects. Thus, this narrative review explores different ...

setting and goal achievement in patients with type 2 diabetes. Nature of the research project This dissertation research is a theory based cross-sectional study using a patient self-administered questionnaire. The exploration of the relationships between support group participation and goal behavior is guided by Social identity theory.

Type 2 Diabetes Mellitus (T2DM) is characterized by chronically elevated blood glucose (hyperglycemia) and elevated blood insulin (hyperinsulinemia). When the blood glucose concentration is 100 milligrams/deciliter the bloodstream of an average adult contains about 5-10 grams of glucose. Carbohydrate-restricted diets have been used effectively to treat obesity and T2DM for over 100 years ...

Clin. Pract. 162 (2021) 108122] Hoda Gad, Hamad Al-Muhannadi, Hana Purra, Paul Mussleman, Rayaz A. Malik. Article 108761. View PDF. Read the latest articles of Diabetes Research and Clinical Practice at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.

Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Metabolic abnormalities in carbohydrates, lipids, and proteins result from the importance of insulin as an anabolic hormone.

DM caused 4.6 million deaths in 2011.8It is estimated that 439 million people would have type 2 DM by the year 2030.9The incidence of type 2 DM varies substantially from one geographical region to the other as a result of environmental and lifestyle risk factors.10.

Diabetes mellitus is a significant global public health challenge, with a rising prevalence and associated morbidity and mortality. Cell therapy has evolved over time and holds great potential in diabetes treatment. In the present review, we discussed the recent progresses in cell-based therapies for diabetes that provides an overview of islet and stem cell transplantation technologies used in ...

Quality of life (QoL)/Health-Related Quality of Life (HRQoL) and diabetes. The World Health Organisation (WHO) has defined QoL as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns."[] QoL is considered an important health outcome, with good quality of ...