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UU Student Theses Repository: Recent submissions
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Development of an in vitro Bone Sarcoma Model for Testing B7H3-Specific, Interleukin-18-Enhanced CAR T Cells
Stochastic modelling of salpingoeca rosetta chain colonies , the compliance of tiktok's infinite scrolling interface with the gdpr , a safe haven the legal and social challenges of lgbtq+ asylum seekers in the netherlands and their impact on mental health. , legacy and reconciliation: the pursuit of justice and peace in northern ireland, a post conflict society , enhancing cross-border collaboration in combatting child sexual abuse: a study on europol's role and the dynamics of information sharing among the european union member states , sustainable manure management in agriculture , parent child-based contingent self-esteem and psychological control on child self-concept clarity: a parent-child dyad study , blood biomarkers for alzheimer’s diseases: moving towards to the early and non-invasive diagnosis. , an air-liquid interface model to investigate the niche preference of campylobacter fetus , werkzame elementen van het werken met intergroepscontact en rolmodellen en de behoefte aan de inzet san rolmodellen in het “move your world” programma: perspectieven van jongeren en student-vrijwilligers , shaping climate change adaptation: the impact of farmers' perceptions , distribution of micro- and nanoplastics within human placental tissue , watersnood in de biesbosch: vroeger en straks. , effect of relative sea level rise on salt marsh change , anticipatory pipeline appraisal: spatial alternative polyadenylation in the human spinal cord , breaking left-to-right generation in transformer models: arbitrary orderings on tagging tasks , towards sustainable medication use: a comprehensive quantification and identification of medication waste in dutch healthcare settings. , what if hal breathed enhancing empathy in human-ai interactions with breathing speech synthesis , pdia3 does not control notch2 signaling in myeloid dendritic cells .
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Pharmacoepidemiology and Clinical Pharmacology
Over the years many students have graduated from our division, writing wonderful PhD theses. Looking through the names of the graduates, familiar names pop up. Some have gone on to become professors, employees of the division or influential voices in the research community. Several of them will have gone on to supervise the theses of later students, including PhD students of other universities throughout the Netherlands.
To celebrate the work of these students over the years, an exhaustive overview of the published PhD theses can now more easily be read here on the website. In the Utrecht University Repository many of these PhD theses can be read in their entirety.
An overview of these PhD theses is included down below, organized by year of graduation.
PhD students at our division
The role of science, practice and education in building capacity for pharmacy and pharmaceutical sciences Kusynova, Z. Supervisory team: prof. dr. A.K. Mantel-Teeuwisse, prof. dr. H.G.M. Leufkens, dr. H.A. van den Ham Utrecht University (Faculty of Science), 10 Jan 2024. Read on Utrecht University Repository
On The Edge Of HTA: Shaping the boundaries across borders and stakeholders to prepare HTA for future complex medicines Hogervorst, M.A. Supervisory team: prof. dr. A.K. Mantel-Teeuwisse, dr. ir. W.G. Goettsch, dr. R.A. Vreman. Utrecht University (Faculty of Science), 12 Jan 2024. Read on Utrecht University Repository
Innovating Health Technology Assessment Methods: Barriers and Enablers illustrated using Qualitative and Quantitative Methods on Real-World Data Jiu, L. Supervisory team: dr. ir. W.G. Goettsch, prof. dr. A.K. Mantel-Teeuwisse, dr. J. Wang. Utrecht University (Faculty of Science), 28 Mar 2024. Read on Utrecht University Repository
Relevance of pharmacological boosters in the disposition of oral anticancer drugs: Mouse models Loos, N. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 10 Apr 2024.
Improving patient access to valuable new pharmaceuticals: Working towards and evidence ecosystem in healthcare Kalf, R.R.J. Supervisory team: dr. ir. W.G. Goettsch, dr. D.M.J. Delnoij, dr. prof. M.L. Bouvy. Utrecht University (Faculty of Science), 13 Apr 2024. Read on Utrecht University Repository
The CombiConsultation: Patient-centred pharmaceutical care by interprofessional collaboration Meijvis, V.A.M. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. N.J. de Wit, dr. H.F. Kwint, dr. M. Heringa. Utrecht University (Faculty of Science), 15 May 2024. Read on Utrecht University Repository
Forging new paths in access to medicines research: Towards equitable access for all Joosse, I.R. Supervisory team: prof. dr. A.K. Mantel-Teeuwisse, dr. prof. F. Suleman, dr. H.A. van den Ham Utrecht University (Faculty of Science), 27 May 2024. Read on Utrecht University Repository
Globalization of orphan drug development: integrating science, regulation, and access Coste, E. Supervisory team: prof. dr. H.G.M. Leufkens, dr. H.A. van den Ham Utrecht University (Faculty of Science), 15 Jul 2024. Read on Utrecht University Repository
External PhD students supervised by staff of our division
We can only keep hoping: Effects of News about Innovative Diabetes Therapies on Patients’ Emotional and Cognitive Responses Vehof, J.H. Supervisory team: prof. dr. H.H.J. Das, prof. dr. J.M. Sanders, dr. E.R. Heerdink. Radboud Universiteit, 16 Jan 2024. Read on HBO Kennisbank
Strategies for sustainable medication use: Waste or wasted opportunities Smale, E.M. Supervisory team: prof. dr. B.J.F. van den Bemt, prof. dr. A.C.G. Egberts, Dr. C.L. Bekker, dr. E.R. Heerdink. Radboud Universiteit, 8 May 2024. Read on GreenThesis
Real-world treatment outcomes in muscle-invasive and metastatic bladder cancer; Towards better use of outcome data Reesink, D.J. Supervisory team: prof. dr. S. Horenblas, prof. dr. D.H. Biesma, dr. H.H.E. van Melick, dr. van de Garde, E.M.W. Utrecht University (Faculty of Science), 6 Jun 2024. Read on Utrecht University Repository
Metabolomics in community-acquired pneumonia: Exploring metabolomics-based biomarkers for diagnosis and treatment response monitoring of community-acquired pneumonia. den Hartog, I. Supervisory team: prof. dr. J.G.C. van Hasselt, prof. dr. T. Hankemeijer, dr. van de Garde, E.M.W. Leiden University, 16 Sep 2024. Read more about it on the Leiden University website
Knowing me, knowing you: the evolution of HTA practice and approaches from the perspectives of HTA Agencies and pharmaceutical industry Wang, T. Supervisory team: prof. dr. M.L. de Bruin, prof. dr. H.G.M. Leufkens, dr. ir. W.G. Goettsch, dr. N. McAuslane. Utrecht University (Faculty of Science), 11 Jan 2023. Read on Utrecht University Repository
In vitro and in silico optimization of oral taxane therapy van Eijk, M. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. A.D.R. Huitema, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 6 Feb 2023. Read on Utrecht University Repository
Target site bioanalysis and pharmacokinetics of antileishmanial drugs Roseboom, I.C. Supervisory team: prof. dr. J.H. Beijnen, dr. T.P.C. Dorlo. Utrecht University (Faculty of Science), 22 Feb 2023. Read on Utrecht University Repository
Monitoring for adverse drug reactions in children and adolescents treated with antipsychotic drugs Minjon, L. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. E.F. van den Ban. Utrecht University (Faculty of Science), 3 Apr 2023. Read on Utrecht University Repository
TNFα inhibitor treatment trajectories: learnings on biosimilars from clinical practice Meijboom, R.W. Supervisory team: prof. dr. A.C.G. Egberts, dr. T.J. Giezen, dr. H. Gardarsdottir. Utrecht University (Faculty of Science), 2 Oct 2023. Read on Utrecht University Repository
Statin treatment in the ageing population Lefeber, G.J. Supervisory team: prof. dr. A. de Boer, prof. dr. M.L. Bouvy, dr. H. Koek, dr. W. Knol. Utrecht University (Faculty of Science), 2 Oct 2023. Read on Utrecht University Repository
Pharmacological and physiological roles of the carboxylesterase 1 enzyme complex Gan, C. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 13 Nov 2023. Read on Utrecht University Repository
Contextualising access to essential medicines: Lessons learned from East and Southern Africa Ooms, G.I. Supervisory team: prof. dr. A.K. Mante-Teeuwisse, dr. H.A. van der Ham, dr. T. Reed. Utrecht University (Faculty of Science), 13 Dec 2023. Read on Utrecht University Repository
Biomarkers for individualizing platinum-based therapy of patients with non-small cell lung cancer de Jong, C. Supervisory team: Prof. dr. A.C.G. Egberts (Utrecht University), dr. V.H.M. Deneer (Utrecht University), dr. G.J.M. Herder (Meander MC). Utrecht University, 23 Mar 2023. Read on Utrecht University Repository
Towards tailored medication self-management: Needs of and support for patients with limited health literacy Visscher, B. Supervisory team: Prof. dr. J. Rademakers (Maastricht University) and dr. E.R. Heerdink (Utrecht University). Maastricht University, 17 Apr 2023. Read on Maastricht University website
Antiplatelet treatment in acute myocardial infarction: from routine treatment to genotype guided personalized medicine Bergmeijer, T.O. Supervisory team: Prof. dr. J.M. ten Berg (Maastricht University), dr. V.H.M. Deneer (Utrecht University), dr. C.M. Hackeng (Antonius Hospital). Maastricht University, 17 May 2023. Read on Maastricht University website
Innovative drug monitoring of factor VIII and emicizumab in haemophilia A Donners, A. Supervisory team: Prof. dr. A.C.G. Egberts (Utrecht University), prof. dr. R.E.G. Schutgens (UMC Utrecht), dr. C.M.A. Rademaker (UMC Utrecht), dr. K. Fischer (UMC Utrecht) Utrecht University, 1 Jun 2023. Read on Utrecht University Repository
Treatment optimization in patients with non-small cell lung cancer van Veelen, A.J. Supervisory team: Prof. dr. V. Tjan-Heijnen (Maastricht University), dr. P.C. Souverein (Utrecht University), dr. S. Croes (Maastricht University), dr. R. van Geel (Maastricht University). Maastricht University, 1 Jun 2023. Read on Maastricht University website
Supporting successful clozapine treatment Beex-Oosterhuis, M.M. Supervisory team: Prof. dr. R.J. van Marum (free University Amsterdam), dr. E.R. Heerdink (Utrecht University). Free University Amsterdam, 9 Jun 2023. Read on Free University Amsterdam website
Clinical decision support-assisted pharmacotherapy optimisation for older hospitalised patients Huibers, C.J.A. Supervisory team: Prof. dr. A.C.G. Egberts (Utrecht University), prof. dr. R.J. van Marum (Free University Amsterdam), dr. W. Knol (UMC Utrecht), dr. I. Wilting (Utrecht University). Utrecht University, 15 Jun 2023. Read on Utrecht University Repository
Pharmacy staff-patient interactions in challenging situations: Understanding the roots and ways to flourish patient-centered communication Schackmann, L. Supervisory: Prof dr. ir. C.E.M.J. van Dijk (Groningen University), dr. E.S. Koster (Utrecht University), dr. M. Vervloet (NIVEL). University of Groningen, 4 Jul 2023. Read on University of Groningen website
Contextualized clinical decision support to detect and prevent adverse drug events Wasylewicz, A.T.M. Supervisory team: Prof. dr. H.H.M. Korsten (Technical University Eindhoven), prof. dr. A.C.G. Egberts (Utrecht University), dr. R.J.E. Grouls (Catharina hospital Eindhoven). Technical University Eindhoven, 7 Jul 2023. Read on Technical University Eindhoven website
Strategies to optimise the treatment of community-acquired pneumonia Wittermans, E. Supervisory team: Prof. dr. Bos, prof. dr. W.J.W., Grutters, J.C., dr. van de Garde, E.M.W. University Leiden, 28 Sept 2023. Read on Leiden University website
New medicines in primary care: perspectives and practices of healthcare professionals Dankers, M. Supervisory team: Prof. dr. ir. L. van Dijk, prof. dr. A.K. Mantel-Teeuwisse, dr. H.J.M.G. Nelissen-Vrancken University of Groningen, 14 Nov 2023 Read on University of Groningen website
Drug exposure assessment in pharmacoepidemiological database studies: Reporting and impact of exposure misclassification Hempenius, M. Supervisory team: prof. dr. O.H. Klungel, prof. dr. A. de Boer, dr. H. Gardarsdottir. Utrecht University (Faculty of Science), 7 Mar 2022 Read on Utrecht University Repository
The pharmacokinetics of targeted anticancer drugs and food toxins: Roles of ABC efflux and OATP uptake transporters Wang, J. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 21 Mar 2022 Read on Utrecht University Repository
Clinical development of anticancer treatment with oral taxanes in combination with ritonavir Vermunt, M.A.C. Supervisory team: prof. dr. J.H. Beijnen, dr. A.M. Bergman, dr. S. Marchetti. Utrecht University (Faculty of Science), 11 May 2022
Real-world data in cancer treatment: Bridging the gap between trials and clinical practice Ismail, R.K. Supervisory team: prof. dr. A. de Boer, prof. dr. M.W.J.M. Wouters, dr. D.L. Hilarius, dr. M. van Dartel. Utrecht University (Faculty of Science), 18 May 2022 Read on Utrecht University Repository
The role of the community pharmacist in fall prevention: The ups and downs of implementation Gemmeke. M. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. K. Taxis, dr. E.S. Koster. Utrecht University (Faculty of Science), 25 May 2022 Read on Utrecht University Repository
Unraveling the functions of detoxification enzymes and drug transporters Wang, Y. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 12 Jul 2022 Read on Utrecht University Repository
Quality of biopharmaceuticals: Comparability exercise and post-approval surveillance Alsamil, A.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. H. Gardarsdottir, dr. T.J. Giezen. Utrecht University (Faculty of Science), 3 Nov 2022 Read on Utrecht University Repository
The role of the community pharmacist in minor ailments, focus on uncomplicated urinary tract infection in women: Focus on uncomplicated urinary tract infection in women Lelie- van der Zande, A.C.A.M. Supervisory team: prof. dr. M.L. Bouvy, dr. E.S. Koster, dr. M. Teichert. Utrecht University (Faculty of Science), 23 Nov 2022 Read on Utrecht University Repository
Medication optimisation in hospitalised older people with polypharmacy and multimorbidity Sallevelt, B.T.G.M. Supervisory team: prof. Egberts, A.C.G., dr. van Puijenbroek, A.A.F.L, dr. Wilting, J. & dr. Knol, E.F. UMCU, 20 Oct 2022 Read on Utrecht University Repository
Real-world treatment outcomes in metastatic lung cancer: from efficacy-effectiveness gap evaluation to informed clinical decision-making Van der Welle, C.M. Supervisory team: dr. E.M.W. van de Garde, dr. F.M.N.H. Schramel, prof. dr. H.J.M. Groen, prof. dr. O.H. Klungel. Utrecht University (Faculty of Science), 29 Mar 2021. Read on Utrecht University Repository
Development, market authorization and market access of gene and cell-based therapies Ten Ham, R.M.T. Supervisory team: dr. J. Hoekman, dr. G.W.J. Frederix, prof. dr. H.G.M. Leufkens, prof. dr. O.H. Klungel. Utrecht University (Faculty of Science), 4 Jun 2021. Read on Utrecht University Repository
Post-marketing safety learning for biologicals: regulatory and clinical insights Minnema, L.A. Supervisory team: dr. H. Gardarsdottir, dr. T.J. Giezen, prof. dr. A.C.G. Egberts, prof. dr. H.G.M. Leufkens. Utrecht University (Faculty of Science), 28 Jun 2021. Read on Utrecht University Repository
Advanced pharmacoepidemiologic approaches to study the utilization, safety, and effectiveness of NOAC treatment in patients with atrial fibrillation Komen, J.J. Supervisory team: dr. T. Forslund, prof. dr. B. Wettermark, prof. dr. A.K. Mantel-Teeuwisse, prof. dr. O.H. Klungel. Utrecht University (Faculty of Science), 30 Jun 2021. Read on Utrecht University Repository
Clinical pharmacology of miltefosine Palić, S. Supervisory team: dr. T.P.C. Dorlo, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 10 Sep 2021. Read on Utrecht University Repository
The changing face of community pharmacy practice: increasing time for our priorities Van de Pol, J.M. Supervisory team: dr. E.S. Koster, prof. dr. M.L. Bouvy. Utrecht University (Faculty of Science), 27 Sep 2021. Read on Utrecht University Repository
Psychotropic medication use in the armed forces: prescription patterns and treatment after trauma Janssen-Knotnerus, D.A. Supervisory team: dr. E.R. Heerdink, prof. dr. H.G.J.M. Vermetten, prof. dr. A.C.G. Egberts. Utrecht University (Faculty of Medicine), 28 Sep 2021. Read on Utrecht University Repository
Access to sexual and reproductive health medicines and supplies in Sub-Saharan Africa Kibira, D. Supervisory team: dr. H.A. van den Ham, T. Reed, prof. dr. H.G.M. Leufkens, prof. dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 10 Nov 2021. Read on Utrecht University Repository
Cyclin-dependent kinase inhibitors in cancer: bioanalysis and pharmacokinetics Martínez Chávez, D.A. Supervisory team: dr. A.H. Schinkel, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 10 Nov 2021. Read on Utrecht University Repository
Moral dilemmas of community pharmacists: reflection on professional values Kruijtbosch, M. Supervisory team: dr. A. Floor-Schreudering, prof. dr. E van Leeuwen, prof. dr. M.L. Bouvy. Utrecht University (Faculty of Science), 17 Nov 2021. Read on Utrecht University Repository
Evidence generation on benefits and risks of medicines and its impact Bloem, L.T. Supervisory team: Prof. dr. A.K. Mantel-Teeuwisse, prof. dr. O.H. Klungel, dr. J. Hoekman, dr. M.E. van der Elst. Utrecht University (Faculty of Science), 24 Nov 2021. Read on Utrecht University Repository
Functions and interplay of drug transporters and CYP3A enzymes Li, W. Supervisory team: Prof. dr. J.H. Beijnen, dr. A.H. S, dr. R.W. Sparidans. Utrecht University (Faculty of Science) 15 Dec 2021. Read on Utrecht University Repository
Development and validation of diagnostic and pharmacodynamic cancer biomarker methods and their (pre)clinical application Pluim D. Supervisory team: Prof. dr. J.H. Beijnen, dr. D. Brandsma. Utrecht University (Faculty of Science) 20 Dec 2021. Read on Utrecht University Repository
Observational studies on skin cancer risk: focus on genetics, alcohol and phototoxic medicines Siiskonen, S.J. Supervisory team: prof. dr. M. Airaksinen (University of Helsinki) & dr. H. Gardarsdottir (Utrecht University) University of Helsinki (Faculty of Pharmacy ), 4 Jun 2021. Read on University of Helsinki Open Repository
Methodological approaches to manage challenges to the implementation of HTA and economic evaluations in Low and Middle-Income Countries (LMICs) Padmasawitri, A. Supervisory team: prof. dr. O.H. Klungel, dr. A.M. Hövels, dr. G.W.J. Frederix. Utrecht University (Faculty of Science), 6 Jan 2020.
Clinical pharmacology of anti-hormonal drugs and oncology - bioanalysis - therapeutic drug monitoring - gemcitabine in oncology - microdosing Van Nuland, M. Supervisory team: prof. dr. J.H. Beijnen, dr. H. Rosing, dr. A.M. Bergman. Utrecht University (Faculty of Science), 22 Jan 2020. Read on Utrecht University Repository
Regulating gene and cell-based therapies as medicinal products Coppens, D.G.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. M.L. De Bruin, dr. J. Hoekman, dr. H. Gardarsdottir. Utrecht University (Faculty of Science), 27 Jan 2020. Read on Utrecht University Repository
Intracellular quantification and pharmacokinetics of pyrimidine analogues used in oncology Derissen, E.J.B. Supervisory team: prof. dr. J.H. Beijnen, dr. H. Rosing. Utrecht University (Faculty of Science), 29 Jan 2020. Read on Utrecht University Repository
Translational research of combined anticancer therapies targeting the MAPK pathway Huijberts, S.C.F.A. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. R. Bernards, dr. N. Steeghs, dr. F. Opdam. Utrecht University (Faculty of Science), 14 Oct 2020. Read on Utrecht University Repository
Health technology assessment throughout the drug lifecycle Vreman, R.A. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.K. Mantel-Teeuwisse, dr. ir. W. Goettsch. Utrecht University (Faculty of Science), 13 Nov 2020. Read on Utrecht University Repository
A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy Heinhuis, K.M. Supervisory team: prof. dr. J.H. Beijnen, dr. N. Steeghs, dr. W.J. van Houdt. Utrecht University (Faculty of Science), 30 Nov 2020. Read on Utrecht University Repository
Overview since 1989
Evolving national pharmacovigilance systems in Africa Ampadu, H.H. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.N.O. Dodoo, dr. J. Hoekman, dr. H. Gardarsdottir. Utrecht University (Faculty of Science), 9 Jan 2019. Read on Utrecht University Repository
Mounting an attack on the glioblastoma triad: proliferation, invasion and resistance De Gooijer, M.C. Supervisory team: prof. dr. J.H. Beijnen, dr. O. van Tellingen. Utrecht University (Faculty of Science), 23 Jan 2019. Read on Utrecht University Repository
Adolescents perspectives on chronic medication use: opportunities for mHealth Kosse, R.C. Supervisory team: prof. dr. M.L. Bouvy, dr. E.S. Koster, dr. T.W. de Vries. Utrecht University (Faculty of Science), 20 Feb 2019. Read on Utrecht University Repository
Clinical medication review: one step beyond: computer rules or personal goals? Verdoorn, M.A. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. J. Gussekloo, dr. H.F. Kwint. Utrecht University (Faculty of Science), 13 Mar 2019. Read on Utrecht University Repository
Pharmacometrics for treatment optimization and drug development in oncology De Vries Schultink, A.H.M. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. A.D.R. Huitema, dr. T.P.C. Dorlo. Utrecht University (Faculty of Science), 29 May 2019. Read on Utrecht University Repository
Non-inferiority studies: a methodological and regulatory perspective Althunian, T.A.I. Supervisory team: prof. dr. A. de Boer, prof. dr. O.H. Klungel, prof. dr. R.H.H. Groenwold. Utrecht University (Faculty of Science), 24 Jun 2019. Read on Utrecht University Repository
Multidose dispensing for older patients in primary care Mertens, B. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. R.J. van Marum, dr. H.F. Kwint. Utrecht University (Faculty of Science), 3 Jul 2019. Read on Utrecht University Repository
Clinical pharmacology of anticancer agents with focus on neuro-oncology and biomarker assessment Van Bussel, M.T.J. Supervisory team: prof. dr. J.H. Beijnen, dr. D. Brandsma. Utrecht University (Faculty of Science), 11 Sept 2019. Read on Utrecht University Repository
Appropriate access to opioid medicines: a legal & policy perspective Vranken, M.J.M. Supervisory team: prof. dr. A.K. Mantel-Teeuwisse, prof. dr. H.G.M. Leufkens, dr. mr. M.D.B. Schutjens. Utrecht University (Faculty of Science), 11 Sept 2019.
Personalized oral anticoagulant treatment: dosing algorithm, drug interactions and economic aspects Zhang, Y. Supervisory team: prof. dr. A. de Boer, prof. dr. A. H. Maitland-Van Der Zee, dr. P.C. Souverein. Utrecht University (Faculty of Science), 16 Sept 2019. Read on Utrecht University Repository
Early phase clinical studies of novel immunotherapeutics in oncology Ros, W. Supervisory team: prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 18 Sept 2019. Read on Utrecht University Repository
The destiny of anti-cancer drugs: the impact of drug transporters and drug-metabolizing enzymes on the pharmacokinetics of anti-cancer therapies Van Hoppe, S.S. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 25 Sept 2019. Read on Utrecht University Repository
Death recording in the clinical practice research datalink Gallagher, A.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. F. de Vries. Utrecht University (Faculty of Science), 21 Oct 2019. Read on Utrecht University Repository
Regulation in the dynamic environment of complex medicines Klein, K. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. M.L. De Bruin, dr. P. Stolk. Utrecht University (Faculty of Science), 23 Oct 2019.
Bioanalysis and biotransformation of tyrosine kinase inhibitors in oncology Rood, J.J.M. Supervisory team: prof. dr. J.H. Beijnen, dr. ir. R.W. Sparidans. Utrecht University (Faculty of Science), 28 Oct 2019.
Approaches to improve the quality and efficiency of clinical pharmacological trials in oncology Roosendaal, J. Supervisory team: prof. dr. J.H. Beijnen, dr. H. Rosing. Utrecht University (Faculty of Science), 30 Oct 2019.
Safety profile of non-steroidal anti-inflammatory drugs in clinical practice Bakhriansyah, M. Supervisory team: prof. dr. A. de Boer, prof. dr. O.H. Klungel. Utrecht University (Faculty of Science), 6 Nov 2019. Read on Utrecht University Repository
Affordability, cost-effectiveness and uncertainty: an integrated approach for decision-making on medicines Geenen, J.W. Supervisory team: prof. dr. O.H. Klungel, dr. A.M. Hövels, dr. C. Boersma. Utrecht University (Faculty of Science), 11 Dec 2019. Read on Utrecht University Repository
Non-dispensing clinical pharmacists in general practice: training, implementation and clinical effects Hazen, A.C.M. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. N.J. de Wit, dr. A.A. de Bont, dr. D.L.M. Zwart. Utrecht University (Faculty of Science), 29 Jan 2018. Read on Utrecht University Repository
Precision medicine steps towards improving treatment with vitamin K antagonists and ACE-inhibitors Baranova, E.V. Supervisory team: prof. dr. A. de Boer, prof. dr. F.W. Asselbergs, prof. dr. A.H. Maitland-van Der Zee. Utrecht University (Faculty of Science), 12 Mar 2018. Read on Utrecht University Repository
Antipsychotics, delirium and glucose in older patients Van Keulen, K. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. W. Knol. Utrecht University (Faculty of Science), 10 Apr 2018. Read on Utrecht University Repository
Real-world evidence for health technology assessment of pharmaceuticals: opportunities and challenges Makady, A.A.M.A. Supervisory team: prof. dr. A. de Boer, prof. dr. J.L. Hillege, prof. dr. O.H. Klungel, dr. W.G. Goettsch. Utrecht University (Faculty of Science), 9 May 2018. Read on Utrecht University Repository
Monitoring patients using psychotropic drugs Nederlof, M. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 11 Jun 2018. Read on Utrecht University Repository
Pharmaceutics of oral anticancer agents and stimulants Herbrink, M. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. B. Nuijen. Utrecht University (Faculty of Science), 27 Jun 2018. Read on Utrecht University Repository
The use and safety of antiretroviral medicines - lessons from Ghana Tetteh, R.A. Supervisory team: prof. dr. A.K. Mantel-Teeuwisse, prof. dr. A.N.O. Dodoo. Utrecht University (Faculty of Science), 11 Jul 2018. Read on Utrecht University Repository
Safety of antihypertensive drugs in clinical practice Alharbi, F.F.M. Supervisory team: prof. dr. A. de Boer, prof. dr. O.H. Klungel. Utrecht University (Faculty of Science), 29 Aug 2018.
The added value of linked data in pharmacoepidemiology: solving the jigsaw puzzle Williams, R.A. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. T.P. van Staa, dr. F. de Vries. Utrecht University (Faculty of Science), 17 Sept 2018. Read on Utrecht University Repository
Human mass balance and metabolite profiling studies of the new anticancer agents plitidepsin, lurbinectedin and niraparib Van Andel, L. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. H. Rosing. Utrecht University (Faculty of Science), 19 Sept 2018. Read on Utrecht University Repository
Individualized dosing of fluoropyrimidines by genotyping and phenotyping of dihydropyrimidine dehydrogenase Henricks, L.M. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. H.J. Guchelaar, prof. dr. J.H.M. Schellens, dr. A. Cats. Utrecht University (Faculty of Science), 24 Sept 2018. Read on Utrecht University Repository
Patient perspectives in pharmaceutical policy: information and influence in the diffusion of new medicines Meneses Leonardo Alves, T.I. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.K. Mantel-Teeuwisse, dr. B.J. Mintzes. Utrecht University (Faculty of Science), 15 Oct 2018. Read on Utrecht University Repository
Precision anticoagulation with vitamin K antagonists in children Maagdenberg, H. Supervisory team: prof. dr. A. de Boer , prof. dr. A.H. Maitland-van der Zee , dr. M.B. Bierings. Utrecht University (Faculty of Science), 10 Dec 2018. Read on Utrecht University Repository
Pharmaceutical policies and access to medicines: a hospital-pharmacy perspective from Ghana Ankrah, D. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. I.A. Agyepong, prof. dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 11 Jan 2017. Read on Utrecht University Repository
Priority medicines for children: exploring age-appropriate medicines and antibiotic use in children Ivanovska, V. Supervisory team: prof. dr. Leufkens, prof. dr. A.K. Mantel-Teeuwisse, dr. ir. C.E.M.J. van Dijk. Utrecht University (Faculty of Science), 8 Mar 2017. Read on Utrecht University Repository
Antiplatelet drugs for secondary prevention of cardiovascular diseases: drug utilization, effectiveness, and safety Noorsyahdy, A.Y. Supervisory team: prof. dr. A. de Boer, prof. dr. O.H. Klungel, dr. V.H.M. Deneer. Utrecht University (Faculty of Science), 13 Mar 2017. Read on Utrecht University Repository
Solid dispersions in oncology: a solution to solubility-limited oral drug absorption Sawicki, E. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. B. Nuijen. Utrecht University (Faculty of Science), 29 Mar 2017. Read on Utrecht University Repository
Towards better fall prevention: examining the interplay between factor that influence gait in older patients De Groot, M.H. Supervisory team: prof. dr. J.H. Beijnen, dr. C.J.C. Lamoth. Utrecht University (Faculty of Science), 10 May 2017.
Clinical pharmacology and bioanalysis of antileishmanial drugs: towards improved treatment strategies for leishmaniasis Kip, A.E. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. T.P.C. Dorlo. Utrecht University (Faculty of Science), 21 Jun 2017. Read on Utrecht University Repository
Pediatric asthma and allergy: an epidemiological approach Arabkhazaeli, A. Supervisory team: prof. dr. J.A.M. Raaijmakers, prof. dr. C.K. van der Ent, prof. dr. A.H. Maitland-van der Zee, dr. S.J.H. Vijverberg. Utrecht University (Faculty of Science), 26 Jun 2017. Read on Utrecht University Repository
Globally applicable facilitated regulatory pathways to improve equitable access to medicines Liberti, L.E.L. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.M. Breckenridge, dr. P. Stolk, dr. N.M. Auslane. Utrecht University (Faculty of Science), 13 Jul 2017. Read on Utrecht University Repository
Unravelling the link between diabetes, insulin treatment and breast cancer Bronsveld, H.K. Supervisory team: prof. dr. A. de Boer, prof. dr. M.L. De Bruin, prof. dr. M.K. Schmidt. Utrecht University (Faculty of Science), 24 Aug 2017. Read on Utrecht University Repository
Optimizing the safety of multidrug-resistant tuberculosis therapy in Namibia Sagwa, E.L. Supervisory team: prof. dr. Leufkens, prof. dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 24 Aug 2017. Read on Utrecht University Repository
The pursuit of user-friendly medicines: older people in the hot seat Notenboom, K. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. H.G.M. Leufkens . Utrecht University (Faculty of Science), 27 Sept 2017. Read on Utrecht University Repository
The role of motivation in continuing education for pharmacists Schouten-Tjin A Tsoi, S. Supervisory team: prof. dr. A. de Boer, prof. dr. G. Croiset, dr. A.S. Koster, dr. R. Kusurkar. Utrecht University (Faculty of Science), 4 Oct 2017. Read on Utrecht University Repository
Trials and tribulations: studies on the fate, transparency and efficiency of clinical drug trials Van den Bogert, C.A. Supervisory team: prof. dr. H.G.M. Leufkens, dr. P.C. Souverein, dr. S.W.J. Janssen. Utrecht University (Faculty of Science), 4 Oct 2017. Read on Utrecht University Repository
Variation in health technology assessment of new medicines: processes and outcomes Lipska, I.L. Supervisory team: prof. dr. H.G.M. Leufkens, dr. A.M. Hövels, dr. N. M. Auslane. Utrecht University (Faculty of Science), 11 Oct 2017. Read on Utrecht University Repository
Readmission to primary care: the role of community pharmacists post-discharge Ensing, H.T. Supervisory team: prof. dr. M.L. Bouvy, dr. E.S. Koster, dr. A.A. van Dooren. Utrecht University (Faculty of Science), 25 Oct 2017. Read on Utrecht University Repository
Clinical decision support in community pharmacy Heringa, M. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. P.A.G.M. de Smet, dr. A. Floor-Schreudering. Utrecht University (Faculty of Science), 30 Oct 2017. Read on Utrecht University Repository
Clinical pharmacology of kinase inhibitors in oncology Verheijen, R.B. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, prof. dr. A.D.R. Huitema, dr. N. Steeghs. Utrecht University (Faculty of Science), 29 Nov 2017. Read on Utrecht University Repository
Early development of targeted anticancer agents Van Brummelen, E.M.J. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 18 Dec 2017. Read on Utrecht University Repository
Clinical pharmacology of novel anticancer agents De Weger, V.A. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. S. Marchetti. Utrecht University (Faculty of Science), 20 Dec 2017. Read on Utrecht University Repository
Assessing long-term and rare adverse effects of medicines Duijnhoven, R.G. Supervisory team: prof. dr. A. de Boer, prof. dr. A.W. Hoes, dr. M.L. De Bruin, dr. S.M.J.M. Straus. Utrecht University (Faculty of Science), 18 Jan 2016. Read on Utrecht University Repository
Understanding differences in findings from pharmacoepidemiological studies: the case of antidepressant and benzodiazepine use and hip fracture Abbing-Karahagopian, V. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. M.L. De Bruin, dr. T.P. van Staa. Utrecht University (Faculty of Science), 19 Jan 2016. Read on Utrecht University Repository
Improving safety and effectiveness of fluoropyrimidine-based chemotherapy Meulendijks, D. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. A Cats. Utrecht University (Faculty of Science), 3 Feb 2016. Read on Utrecht University Repository
Access to essential medicines in low and middle income countries Taghipour Bazargani, Y. Supervisory team: prof. dr. A. de Boer, prof. dr. H.G.M. Leufkens, dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 9 May 2016.
Patients at increased fracture risk: identification and pharmacological treatment Klop, C. Supervisory team: prof. dr. H.G.M. Leufkens , prof. dr. J.W.J. Bijlsma, dr. F. de Vries, dr. P.M.J. Welsing. Utrecht University (Faculty of Science), 23 May 2016. Read on Utrecht University Repository
Benefits and risks for the individual, anticoagulation for patients with atrial fibrillation van den Ham, H.A. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. O.H. Klungel, prof. dr. T.P. van Staa. Utrecht University (Faculty of Science), 25 May 2016. Read on Utrecht University Repository
Harmonising relative effectiveness assessments of medicines in Europe Kleijnen, S. Supervisory team: prof. dr. A. de Boer, prof. dr. H.G.M. Leufkens, dr. W.G. Goettsch. Utrecht University (Faculty of Science), 30 May 2016. Read on Utrecht University Repository
Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studies Nijenhuis, C.M. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. H. Rosing. Utrecht University (Faculty of Science), 15 Jun 2016.
Adverse drug reactions of angiotensin converting enzyme inhibitors: towards precision medicin Mahmoud Pour, S.H. Supervisory team: prof. dr. A. de Boer, prof. dr. F.W. Asselbergs, dr. A.H. Maitland-van der Zee. Utrecht University (Faculty of Science), 29 Jun 2016. Read on Utrecht University Repository
Adjusted indirect treatment comparisons of bioequivalence studies Gwaza, L. Supervisory team: prof. dr. H.G.M. Leufkens, dr. M. Maliepaard, dr. A. Garcia-Arieta. Utrecht University (Faculty of Science), 8 Jul 2016. Read on Utrecht University Repository
Pharmacokinetic-pharmacodynamic modelling & simulation for anticancer drugs with complex absorption characteristics Yu, H. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, prof. dr. A.D.R. Huitema. Utrecht University (Faculty of Science), 31 Aug 2016.
Etiological studies in complex diseases Peeters, P.J.H.L. Supervisory team: prof. dr. H.G.M. Leufkens, dr. M.L. de Bruin. Utrecht University (Faculty of Science), 26 Sept 2016. Read on Utrecht University Repository
Clinical pharmacology of genotype-directed anticancer therapy: towards rational combination strategies van Geel, R.M.J.M. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 5 Oct 2016. Read on Utrecht University Repository
Risk factors and treatment of pediatric chronic diseases: type 1 diabetes, asthma and allergy Ahmadizar, F. Supervisory team: prof. dr. A. de Boer, prof. dr. A.H. Maitland-van der Zee. Utrecht University (Faculty of Science), 23 Oct 2016. Read on Utrecht University Repository
Evaluating pharmaceutical policies using cross-national comparisons and time series analysis Santa Ana Tellez, Y. Supervisory team: prof. dr. H.G.M. Leufkens, dr. A.K. Mantel-Teeuwisse, dr. V.J. Wirtz. Utrecht University (Faculty of Science), 26 Oct 2016. Read on Utrecht University Repository
Methods for improving the safety of fluoropyrimidine anticancer drugs Jacobs, B.A.W. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. B. Nuijen. Utrecht University (Faculty of Science), 30 Nov 2016. Read on Utrecht University Repository
Continuous innovation in the drug life cycle Langedijk, J. Supervisory team: prof. dr. H.G.M. Leufkens, dr. A.K. Mantel, dr. mr. M.D.B. Schutjens. Utrecht University (Faculty of Science), 19 Dec 2016. Read on Utrecht University Repository
Revisiting health system performance assessment in Africa Achoki, T.N. Supervisory team: prof. dr. H.G.M. Leufkens, dr. A.M. Hövels. Utrecht University (Faculty of Science), 21 Dec 2016. Read on Utrecht University Repository
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthma Leusink, M. Supervisory team: prof. dr. A. de Boer, prof. dr. P.I.W. de Bakker, dr. A.H. Maitland, dr. N.C. Onland-Moret. Utrecht University (Faculty of Science), 7 Jan 2015. Read on Utrecht University Repository
Access to medicines: common problems, common solutions? Stephens, P.N. Supervisory team: prof. dr. H.G.M. Leufkens. Utrecht University (Faculty of Science), 12 Jan 2015. Read on Utrecht University Repository
Pediatric type 1 and 2 diabetes mellitus: epidemiology, comorbidities, and medication utilization Fazelifarsani, S. Supervisory team: prof. dr. A. de Boer, prof. dr. C.A.J. Knibbe, dr. M van der Vorst, dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 19 Jan 2015. Read on Utrecht University Repository
Challenges in the clinical development of orphan drugs Kreeftmeijer-Vegter, A.R. Supervisory team: prof. dr. A. de Boer, dr. P.J. de Vries. Utrecht University (Faculty of Science), 9 Feb 2015. Read on Utrecht University Repository
Novel systemic treatment options for advanced solid tumors with or without central nervous system metastases or malignant glioma Milojkovic Kerklaan, B.M.K. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. D. Brandsma. Utrecht University (Faculty of Science), 25 Mar 2015. Read on Utrecht University Repository
Antidepressant use in pregnancy: knowledge transfer and translation of research findings Einarson, A. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 8 Apr 2015. Read on Utrecht University Repository
Continuity of pharmaceutical care for psychiatric patients Abdullah-Koolmees, H. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. H. Gardarsdottir. Utrecht University (Faculty of Science), 29 Apr 2015. Read on Utrecht University Repository
Trust in the pharmaceutical sector: analysis of drug safety controversies by means of drug life cycles Hernandez, J.F. Supervisory team: prof. dr. A.H.L.M. Pieters, prof. dr. J.A.M. Raaijmakers, dr. A.K. Mantel-Teeuwisse, dr. G.J.M.W. van Thiel. Utrecht University (Faculty of Science), 3 Jun 2015. Read on Utrecht University Repository
Supporting patients: pharmacy based interventions to improve medication adherence Kooij, M.J. Supervisory team: prof. dr. M.L. Bouvy, dr. E.R. Heerdink, dr. ir. C.E.M.J. van Dijk. Utrecht University (Faculty of Science), 9 Sept 2015. Read on Utrecht University Repository
Psychotropic drug use in people with intellectual disability: patterns of use and critical evaluation: patterns of use and critical evaluation Scheifes, A. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. H. Nijman, dr. E.R. Heerdink, dr. J.J. Stolker. Utrecht University (Faculty of Science), 7 Oct 2015. Read on Utrecht University Repository
Pharmacovigilance of biologicals: dynamics in post-approval safety learning Vermeer, N.S. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. M.L. De Bruin, dr. S.M.J.M. Straus. Utrecht University (Faculty of Science), 14 Oct 2015. Read on Utrecht University Repository
The RT-18: a new instrument to assess adolescent and young adult risk-taking behavior Haan, de L. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 16 Dec 2015. Read on Utrecht University Repository
Pharmaceutical policy analysis – a European perspective on pricing and reimbursement in challenging times Leopold, C. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R. Laing, dr. A.K. Mantel-Teeuwisse, dr. S. Vogler. Utrecht University (Faculty of Science), 8 Jan 2014.
Complications of hip and knee replacement surgery: a pharmaco-epidemiological approach Lalmohamed, A. Supervisory team: prof. dr. A. de Boer, prof. dr. H.G.M. Leufkens, prof. dr. T.P. van Staa, dr. F. de Vries. Utrecht University (Faculty of Science), 27 Jan 2014. Read on Utrecht University Repository
Population-based studies on risk of fracture in patients with neurological disorders Pouwels, S. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A. de Boer, prof. dr. T.P. van Staa, dr. F. de Vries. Utrecht University (Faculty of Science), 27 Jan 2014. Read on Utrecht University Repository
Integrated quantitative pharmacology for treatment optimization in oncology Van Hasselt, J.G. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. A.D.R. Huitema. Utrecht University (Faculty of Science), 29 Jan 2014. Read on Utrecht University Repository
Disease and drug-induced arrhythmias: the example of obstructive pulmonary disease Warnier, M.J. Supervisory team: prof. dr. A. de Boer, prof. dr. A.W. Hoes, dr. M.L. de Bruin, dr. F.H. Rutten. Utrecht University (Faculty of Science), 10 Feb 2014. Read on Utrecht University Repository
Treatment response in childhood asthma. An interplay of genes and inflammatory signals Vijverberg, S.J.H. Supervisory team: prof. dr. J.A.M. Raaijmakers, prof. dr. L. Koenderman, dr. A.H. Maitland-van der Zee. Utrecht University (Faculty of Science), 9 Apr 2014. Read on Utrecht University Repository
Translational pharmacology and bioanalysis of oral taxanes Hendrikx, J.J.M.A. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. H. Rosing, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 16 Apr 2014. Read on Utrecht University Repository
Lithium in older patients: treatment patterns and somatic adverse effects Van Melick, E.J.M. Supervisory team: prof. dr. A.C.G. Egberts, dr. I. Wilting. Utrecht University (Faculty of Science), 17 Apr 2014. Read on Utrecht University Repository
Anti-cancer drug disposition: in vitro and in vivo functions of ABC efflux and OATP uptake transporters Durmus, S. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 5 Sept 2014. Read on Utrecht University Repository
Childhood obesity: medical, cultural and psychological factors Radhakishun, N.N.E. Supervisory team: Prof. dr. J.H. Beijnen, prof. dr. M.H.H. Kramer, prof. dr. D.P.M. Brandjes. Utrecht University (Faculty of Science), 10 Sept 2014. Read on Utrecht University Repository
Safety, pharmacokinetics and preliminary anti-tumor activity of novel (combinations of) targeted anti-cancer drugs Van Noll, R. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 15 Sept 2014.
Bioanalysis and clinical pharmacology of tamoxifen in breast cancer. Jager, N.G.L. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens Utrecht University (Faculty of Science), 17 Sept 2014. Read on Utrecht University Repository
Improving propensity score methods in pharmacoepidemiology Ali, M.S. Supervisory team: prof. dr. A. de Boer, prof. dr. A.W. Hoes, prof. dr. O.H. Klungel, dr. R.H.H. Groenwold. Utrecht University (Faculty of Science), 1 Oct 2014. Read on Utrecht University Repository
Child friendly medicines. Availability, pharmaceutical design, usability and patient outcomes Riet-Nales, D.A. Supervisory team: prof. dr. A.F.A.M. Schobben, prof. dr. A.C.G. Egberts, dr. C.M.A. Rademaker. Utrecht University (Faculty of Science), 26 Nov 2014. Read on Utrecht University Repository
Performance of statistical methods to control for unmeasured confounding in pharmacoepidemiology. Focus on instrumental variable analysis Uddin, M.J. Supervisory team: prof. dr. A. de Boer, prof. dr. K.C.B. Roes, dr. R.H.H. Groenwold, dr. O.H. Klungel. Utrecht University (Faculty of Science), 15 Dec 2014. Read on Utrecht University Repository
Understanding access to medicines in low- and middle-income countries through the use of price and availability indicators Cameron, A.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R. Laing, dr. A.K. Mantel-Teeuwisse. Utrecht University (Faculty of Science), 10 Jan 2013. Read on Utrecht University Repository
Bioanalysis and clinical pharmacology of tyrosine kinase inhibitors Lankheet, A.G. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. A.D.R. Huitema. Utrecht University (Faculty of Science), 13 Feb 2013. Read on Utrecht University Repository
Targeted therapies for malignant gliomas: novel agents, same barrier Lin, F. Supervisory team: prof. dr. J.H. Beijnen, dr. O. van Tellingen. Utrecht University (Faculty of Science), 1 Mar 2013. Read on Utrecht University Repository
Development of combination therapy with anti-cancer drugs Leijen, S. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 15 Mar 2013. Read on Utrecht University Repository
Cross-country variation in medicines use: a pharmaceutical system perspective Hoebert, J.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R. Laing, dr. A.K. Mantel-Teeuwisse, dr. ir. C.E.M.J. van Dijk. Utrecht University (Faculty of Science), 8 Apr 2013. Read on Utrecht University Repository
Towards optimal dosing of coumarin derivatives: the role of pharmacogenetics Van Schie, R.M.F. Supervisory team: prof. dr. A. de Boer, dr. A.H. Maitland-van der Zee, dr. F.J.M. van der Meer. Utrecht University (Faculty of Science), 10 Apr 2013. Read on Utrecht University Repository
Bioanalysis and clinical pharmacology of antiviral drugs - focus on HIV and influenza Kromdijk, W. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. A.D.R. Huitema, dr. J.W. Mulder. Utrecht University (Faculty of Science), 24 Apr 2013.
Clinical pharmacokinetic interactions between herbal supplements and anticancer drugs Goey, A.K.L. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. ir. I. Meijerman. Utrecht University (Faculty of Science), 15 May 2013. Read on Utrecht University Repository
Improving appropriate medication use for older people in primary care Kwint, H.F. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. J. Gussekloo, dr. A. Faber. Utrecht University (Faculty of Science), 29 May 2013. Read on Utrecht University Repository
Disease specific methods for economic evaluations of breast cancer therapies Frederix, G.W.J. Supervisory team: prof. dr. J.H.M. Schellens, dr. J.L. Severens, dr. A.M. Hövels. Utrecht University (Faculty of Science), 12 Jun 2013. Read on Utrecht University Repository
Marketing authorisation of new medicines in the EU: towards evidence-based improvement Putzeist, M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.W. Hoes, dr. A.K. Mantel-Teeuwisse, dr. C.C. Gispen-de Wied. Utrecht University (Faculty of Science), 19 Jun 2013. Read on Utrecht University Repository
Medicine on demand, medication patterns and glycemic control in patients with type 2 diabetes Lamberts, E.J.F. Supervisory team: prof. dr. M.L. Bouvy, prof. dr. M.G.A.A.M. Nijpels, dr. P.C. Souverein, dr. J.G. Hugtenburg. Utrecht University (Faculty of Science), 19 Jun 2013. Read on Utrecht University Repository
Exploring the regulatory decision-making process for medicines Tafuri, G. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R. Laing. Utrecht University (Faculty of Science), 1 Jul 2013. Read on Utrecht University Repository
Impact of apical ABC transporters on pharmacokinetics of targeted anticancer drugs Tang, S.C. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 3 Jul 2013. Read on Utrecht University Repository
Drug trafficking in mice: in vivo functions of OATP uptake and ABC efflux transporters Iusuf, D. Supervisory team: prof. dr. J.H. Beijnen, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 11 Sept 2013. Read on Utrecht University Repository
Clinical pharmacology of novel anticancer drug formulations Stuurman, F.E. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 18 Sept 2013. Read on Utrecht University Repository
Development of an oral dosage form of capecitabine with modified release characteristics Meulenaar, J. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. B. Nuijen. Utrecht University (Faculty of Science), 25 Sept 2013. Read on Utrecht University Repository
Production and pharmaceutical formulation of plasmid DNA vaccines Van der Heijden, I. Supervisory team: prof. dr. J.H. Beijnen, dr. B. Nuijen. Utrecht University (Faculty of Science), 16 Oct 2013. Read on Utrecht University Repository
Development and clinical application of oral dosage forms of taxanes Moes, J.J. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. B. Nuijen. Utrecht University (Faculty of Science), 30 Oct 2013. Read on Utrecht University Repository
Personalised treatment with oral anticoagulant drugs: clinical and economic issues Verhoef, T.I. Supervisory team: prof. dr. A. de Boer, dr. A.H. Maitland-van der Zee, dr. W.K. Redekop. Utrecht University (Faculty of Science), 20 Nov 2013. Read on Utrecht University Repository
Effects of Complementary and Alternative Medicines (CAM) on the metabolism and transport of anticancer drugs Mooiman, K.D. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. ir. I. Meijerman. Utrecht University (Faculty of Science), 18 Dec 2013. Read on Utrecht University Repository
Measuring and prediction medication adherence using dispensing data and patient beliefs Geers, H.C.J. Supervisory team: prof. dr. M.L. Bouvy, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 1 Feb 2012. Read on Utrecht University Repository
Genetic determinants for metabolic abnormalities Risselada, A.J. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. H. Mulder. Utrecht University (Faculty of Science), 8 Feb 2012. Read on Utrecht University Repository
Transitional pharmaceutical care for patients discharged from the hospital Karapinar, F. Supervisory team: prof. dr. A.C.G. Egberts, dr. P.M.L.A. van den Bemt, dr. S.D. Borgsteede. Utrecht University (Faculty of Science), 25 Apr 2012. Read on Utrecht University Repository
Bioanalysis and metabolite identification of anticancer drugs in mass balance studies Dubbelman, A.C. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. H. Rosing. Utrecht University (Faculty of Science), 23 May 2012. Read on Utrecht University Repository
Pandemic influenza A (H1N1) and other respiratory pathogens: clinical insights - from epidemiology to treatment Smit, P.M. Supervisory team: prof. dr. J.H. Beijnen, dr. J.W. Mulder, dr. D.P.M. Brandjes. Utrecht University (Faculty of Science), 11 Jun 2012.
Antineoplastic drugs in veterinary oncology: excretion in dogs, contamination of the environment and exposure assessment of people at risk Janssens, T. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. E.E.M. Brouwers. Utrecht University (Faculty of Science), 5 Oct 2012. Read on Utrecht University Repository
Non-inferiority trials: methodological and regulatory challenges Wangge, G. Supervisory team: prof. dr. A. de Boer, prof. dr. A.W. Hoes, dr. M.J. Knol, dr. O.H. Klungel. Utrecht University (Faculty of Science), 5 Nov 2012. Read on Utrecht University Repository
Genetic determinants of antipsychotic drug response Gregoor, J.G. Supervisory team: prof. dr. A.C.G. Egberts, dr. J. van der Weide, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 14 Nov 2012. Read on Utrecht University Repository
Laboratory markers in personalized drug therapy Geerts, A.F.J. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. W.W. van Solinge, prof. dr. P.G.A.M. de Smet, dr. G.H.P. de Koning. Utrecht University (Faculty of Science), 28 Nov 2012. Read on Utrecht University Repository
A combinatorial approach to electronic healthcare records in pharmacoepidemiology Bazelier, M.T. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. T.P. van Staa, dr. F. de Vries. Utrecht University (Faculty of Science), 19 Dec 2012. Read on Utrecht University Repository
Treatment optimization of fluoropyrimidines as single agent and in combination therapy Deenen, M.J. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. A. Cats. Utrecht University (Faculty of Science), 26 Jan 2011. Read on Utrecht University Repository
Intravenous-to-oral switch in anticancer chemotherapy: focus on taxanes and gemcitabine Koolen, S.L.W. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen, dr. A.D.R. Huitema. Utrecht University (Faculty of Science), 16 Feb 2011. Read on Utrecht University Repository
Influence of genetic variants and drug interactions on the response to antiplatelet drugs Harmsze, A.M. Supervisory team: prof. dr. A. de Boer, dr. V.H.M. Deneer, dr. O.H. Klungel. Utrecht University (Faculty of Science), 9 Mar 2011. Read on Utrecht University Repository
Evaluation and management of side effects of breast cancer treatment Boekhout, A.H. Supervisory team: prof. dr. J.H.M. Schellens, prof. dr. J.H. Beijnen. Utrecht University (Faculty of Science), 16 Mar 2011. Read on Utrecht University Repository
Risk management of biologicals: a regulatory and clinical perspective Giezen, T.J. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. A.K. Mantel, dr. S.M.J.M. Straus. Utrecht University (Faculty of Science), 21 Mar 2011. Read on Utrecht University Repository
Pharmacogenetics of antihypertensive drugs and the risk of diabetes Bozkurt, O. Supervisory team: prof. dr. A. de Boer, prof. dr. D.E. Grobbee, dr. O.H. Klungel. Utrecht University (Faculty of Science), 30 Mar 2011. Read on Utrecht University Repository
The context of medicines’ use in benefit-risk evaluation Willemen, M.J.C. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. A.K. Mantel-Teeuwisse, dr. S.M.J.M. Straus. Utrecht University (Faculty of Science), 20 Apr 2011. Read on Utrecht University Repository
Melatonin in sleepless children: everything has a rhythm? Van Geijlswijk, I.M. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. H. Vaarkamp, dr. M.G. Smits. Utrecht University (Faculty of Science), 27 Apr 2011. Read on Utrecht University Repository
Bioanalysis and metabolism of tamoxifen and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine - applications in pharmacology Teunissen, S.F. Supervisory team: prof. dr. J.H. Beijnen, prof. dr. J.H.M. Schellens, dr. H. Rosing, dr. A.H. Schinkel. Utrecht University (Faculty of Science), 25 May 2011.
Balancing the benefits and risks of antipsychotic use in elderly patients Kleijer, B. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. M.W. Ribbe, dr. R.J. van Marum, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 19 Oct 2011. Read on Utrecht University Repository
Antipsychotic induced parkinsonism in the elderly: assessment, causes and consequences Knol, W. Supervisory team: prof. dr. A.F.A.M. Schobben, prof. dr. A.C.G. Egberts, dr. R.J. van Marum, dr. P.A.F. Jansen. Utrecht University (Faculty of Science), 21 Oct 2011. Read on Utrecht University Repository
Medication changes in patients transitioning between health care settings Stuffken, R. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 23 Nov 2011. Read on Utrecht University Repository
Towards better treatment outcomes in childhood asthma Koster, E.S. Supervisory team: prof. dr. J.A.M. Raaijmakers, dr. A.H. Maitland-van der Zee. Utrecht University (Faculty of Science), 26 Oct 2011. Read on Utrecht University Repository
Innovative approaches for pharmaceutical policy research in developing countries: the view through a market lens Waning, B.J. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R. Laing. Utrecht University (Faculty of Science), 19 Dec 2011. Read on Utrecht University Repository
Comparative information on new medicines: availability, quality and usage Van Luijn, J.C.F. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. F.W.J. Gribnau. Utrecht University (Faculty of Science), 13 Jan 2010. Read on Utrecht University Repository
From research on rare diseases to new orphan drug development Heemstra, H.E. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. H.A. Büller, dr. S van Weely, dr. R.L.A. Vrueh. Utrecht University (Faculty of Science), 3 Feb 2010. Read on Utrecht University
Markers for disease severity: pharmacoepidemiological studies on obstructive lung disease Velthove, K.J. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. W.W. van Solinge, dr. R.C. Schweizer, dr. P.C. Souverein. Utrecht University (Faculty of Science), 19 Feb 2010. Read on Utrecht University Repository
Pharmacotherapy and aggressive behaviour in psychiatric patients Goedhard, L.E. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. H.L.I. Nijman, dr. E.R. Heerdink, dr. J.J. Stolker. Utrecht University (Faculty of Science), 16 Jun 2010. Read on Utrecht University Repository
Mechanism-based drug exposure classification in pharmacoepidemiological studies Verdel, B.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts, dr. P.C. Souverein. Utrecht University (Faculty of Science), 29 Sept 2010. Read on Utrecht University Repository
Methodological approaches to the pharmacogenomics of statins Peters, B.J.M. Supervisory team: prof. dr. A. de Boer, dr. A.H. Maitland-van der Zee, dr. O.H. Klungel. Utrecht University (Faculty of Science), 12 Dec 2010. Read on Utrecht University Repository
Laboratory markers in drug safety research: studies on drug-induced thrombocytopenia Ten Berg, M.J. Supervisory team: prof. dr. W.W. van Solinge, prof. dr. A.C.G. Egberts, dr. P.M.L.A. van den Bemt, dr. A. Huisman. Utrecht University (Faculty of Science), 17 Jun 2009. Read on Utrecht University Repository
Pharmacogenetics of antihypertensive drug treatment - design and conduct of an observational study Van Wieren-de Wijer, B.M.A. Supervisory team: prof. dr. A. de Boer, prof. dr. B.H.Ch. Stricker, dr. O.H. Klungel, dr. A.H. Maitland-van der Zee. Utrecht University (Faculty of Science), 7 Oct 2009.
Drug treatment episodes in pharmacoepidemiology - antidepressant use as a model Gardarsdottir, H. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 21 Oct 2009. Read on Utrecht University Repository
Influence of antidepressants on glucose homeostasis: effects and mechanisms Derijks, H.J. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. G.H.P. de Koning, dr. R. Janknegt. Utrecht University (Faculty of Science), 11 Nov 2009.
Costs and effects of statin therapy in daily practice Gumbs, P.D. Supervisory team: prof. dr. A. de Boer, dr. O.H. Klungel, dr. W.M.M. Verschuren. Utrecht University (Faculty of Science), 19 Mar 2008.
Adherence to inhaled corticosteroids and patient perception: towards a better understanding and individualised care Menckeberg, T.T. Supervisory team: prof. dr. J.A.M. Raaijmakers, prof. dr. J.W.J. Lammers, dr. M.L. Bouvy, dr. M. Bracke. Utrecht University (Faculty of Science), 20 Mar 2008. Read on Utrecht University Repository
Patterns and clinical outcomes of lithium treatment Wilting, I. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. W.A. Nolen, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 9 Apr 2008. Read on Utrecht University Repository
From new molecules to leads for innovation: studies on the post-innovation learning cycle for pharmaceuticals Stolk, P. Supervisory team: prof. dr. H.G.M. Leufkens, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 15 Sept 2008. Read on Utrecht University Repository
Children and asthma medication: when is that inhaler just a breath away? Zuidgeest, M.G.P. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. ir. B. Brunekreef, dr. M. Bracke, dr. H.A. Smit. Utrecht University (Faculty of Science), 8 Oct 2008. Read on Utrecht University Repository
Initiation, execution and discontinuation of antidepressant therapy: considerations and decisions of patients Van Geffen, E.C.G. Supervisory team: prof. dr. A.C.G. Egberts, dr. E.R. Heerdink, dr. R.P. Van Hulten. Utrecht University (Faculty of Science), 29 Oct 2008. Read on Utrecht University Repository
Systemic inflammatory responses in asthma Ten Hove, W. Supervisory team: prof. dr. J.A.M. Raaijmakers, prof. dr. L. Koenderman, dr. M. Bracke. Utrecht University (Faculty of Science), 31 Jan 2007. Read on Utrecht University Repository
Unintended effects of inhaled corticosteroids: disease or drugs? De Vries, F. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. J.W.J. Lammers, dr. T.P. van Staa, dr. M. Bracke. Utrecht University (Faculty of Science), 15 Feb 2007. Read on Utrecht University Repository
Effects of CYP2C9 and VKORC1 polymorphisms and drug interactions on coumarin anticoagulation control Schalekamp, T. Supervisory team: prof. dr. A. de Boer. Utrecht University (Faculty of Science), 7 May 2007. Read on Utrecht University Repository
CYP2D6 and HTR2C polymorphisms in psychiatric pharmacotherapy Mulder, J. Supervisory team: prof. dr. A.C.G. Egberts, dr. F.W. Wilmink. Utrecht University (Faculty of Science), 2 Jul 2007. Read on Utrecht University Repository
The gastrointestinal and cardiovascular safety of COX-2 selective inhibitors in general practice: the contribution of prescription-event monitoring Layton, D. Supervisory team: prof. dr. A.C.G. Egberts. Utrecht University (Faculty of Science), 29 Oct 2007. Read on Utrecht University Repository
Drug effects on the risk and prognosis of community-acquired pneumonia Van de Garde, E.M.W. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. J.M.M. van den Bosch, dr. P.C. Souverein, dr. V.H.M. Deneer. Utrecht University (Faculty of Science), 21 Nov 2007. Read on Utrecht University Repository
Methods to adjust for confounding. Propensity scores and instrumental variables Martens, E.P. Supervisory team: prof. dr. A. de Boer, dr. O.H. Klungel, dr. W.R. Pestman. Utrecht University (Faculty of Science), 10 Dec 2007. Read on Utrecht University Repository
Pharmaceutical care in diabetes Storimans, M.J. Supervisory team: prof. dr. C.J. de Blaey, dr. H. Talsma, dr. O.H. Klungel. Utrecht University (Faculty of Science), 18 Jan 2006. Read on Utrecht University Repository
Prevention of cardiovascular diseases Van der Elst, M.E. Supervisory team: prof. dr. A. de Boer, prof. dr. C.J. de Blaey, dr. M.L. Bouvy. Utrecht University (Faculty of Science), 16 Feb 2006. Read on Utrecht University Repository
New drugs in general practice: prescribing patterns and external influences Florentinus, S.R. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. P.P. Groenewegen, dr. E.R. Heerdink, dr. ir. C.E.M.J. van Dijk. Utrecht University (Faculty of Science), 18 May 2006. Read on Utrecht University Repository
Clinical risk management in community pharmacy Buurma, H. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. P.G.A.M. de Smet. Utrecht University (Faculty of Science), 4 Oct 2006. Read on Utrecht University Repository
Adherence and persistence with antihypertensive drugs Van Wijk, B.L.G. Supervisory team: prof. dr. A. de Boer, dr. O.H. Klungel, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 6 Dec 2006. Read on Utrecht University Repository
Antipsychotics in daily clinical practice: patterns, choices and consequences Hugenholtz, G.W.K. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. W.A. Nolen, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 7 Dec 2005.
Molecular mechanisms of disease in hereditary red blood cell enzymopathies Van Wijk, H.A. Supervisory team: prof. dr. W.W. van Solinge, prof. dr. J.J.M. Marx, dr. G. Rijksen. Utrecht University (Faculty of Science), 9 Mar 2004. Read on Utrecht University Repository
Quality and safety aspects of lipid-lowering drug use Mantel-Teeuwisse, A.K. Supervisory team: prof. dr. A. de Boer, prof. dr. A.J. Porsius, dr. O.H. Klungel, dr. W.M.M. Verschuren. Utrecht University (Faculty of Science), 26 May 2004.
Drug-induced arrhythmias, quantifying the problem De Bruin, M.L. Supervisory team: prof. dr. H.G.M. Leufkens, H.G.M, prof. dr. A.W. Hoes. Utrecht University (Faculty of Science), 12 Dec 2004. Read on Utrecht University Repository
Transitions in migraine treatment: barriers and opportunities Rahimtoola, H. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. H.G.M. Leufkens, dr. C.C. Tijssen. Utrecht University (Faculty of Science), 7 Apr 2003.
Pharmacoepidemiological studies with cancer as outcome Beiderbeck, A.B. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. B.H.Ch. Stricker, dr. M.C.J.M. Sturkenboom. Utrecht University (Faculty of Science), 2 Jun 2003.
Pharmacoepidemiological determinants of exacerbations of chronic obstructive lung diseases Gerrits, C.M.J.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. J.W.J. Lammers, dr. R.M.C. Herings. Utrecht University (Faculty of Science), 2 Sept 2003.
Pharmacogenetics of HMG-CoA reductase inhibitors Maitland-van der Zee, A.H. Supervisory team: prof. dr. A. de Boer, prof. dr. H.G.M. Leufkens, dr. O.H. Klungel. Utrecht University (Faculty of Science), 17 Sept 2003.
Quality of the pharmacological treatment of patients with Parkinson's disease Van de Vijver, D.A.M.C. Supervisory team: prof. dr. A.J. Porsius, prof. dr. R.A.C. Roos, Prof. Dr. A. de Boer. Utrecht University (Faculty of Science), 30 Jan 2002.
Drug-induces extrapyramidal syndromes Schillevoort, I.E.R.M. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. R.A.C. Roos, dr. R.M.C. Herings. Utrecht University (Faculty of Science), 28 Feb 2002.
Drug therapy in heart failure: studies on prescribing, drug induced problems and compliance Bouvy, M.L. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.W. Hoes, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 18 Mar 2002. Read on Utrecht University Repository
Assessment and diffusion of biotechnology drugs Zwart-van Rijkom, J.E.F. Supervisory team: prof. dr. A.W. Broekmans, prof. dr. F.F.H. Rutten. Utrecht University (Faculty of Science), 8 Apr 2002. Read on Utrecht University Repository
Pharmacotherapy in type 2 diabetes mellitus patients: beyond glycaemic control Erkens, J.A. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. D.E. Grobbee, dr. O.H. Klungel, dr. R.P. Stolk. Utrecht University (Faculty of Science), 21 May 2002.
The value of observational research on antidepressant use: a broadened perspective Meijer, W.E.E. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. W.A. Nolen, dr. E.R. Heerdink. Utrecht University (Faculty of Science), 16 Oct 2002.
Implementation of patient education in Dutch community pharmacies Pronk, M.C.M. Supervisory team: prof. dr. A. Bakker, prof. dr. E.M. Rogers, dr. A.T.G. Blom, dr. R. Jonkers. Utrecht University (Faculty of Science), 28 Oct 2002.
Detection and elucidation of adverse neuropsychiatric drug effects Movig, K.L.L. Supervisory team: prof. dr. A.C.G. Egberts, prof. dr. H.G.M. Leufkens. Utrecht University (Faculty of Science), 28 Nov 2002.
Drug effects in high-risk patients Souverein, P.C. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts. Utrecht University (Faculty of Science), 16 Dec 2002.
Effects of outreach strategies on quality of pharmacotherapy Van Eijk, M.E.C. Supervisory team: prof. dr. A.J. Porsius, dr. A. de Boer. Utrecht University (Faculty of Science), 19 Jun 2001. Read on Utrecht University Repository
Quantitative signal detection in pharmacovigilance Van Puijenbroek, E.P. Supervisory team: prof. dr. H.G.M. Leufkens, prof. dr. A.C.G. Egberts. Utrecht University (Faculty of Science), 1 Oct 2001.
Postmarketing Surveillance of Proton Pump Inhibitors in Perspective: The Case of Lansoprazole Bodewes-Claessens, A. Supervisory team: Prof. dr. H.G.M. Leufkens, prof. dr. C.B.H.W. Lamers, dr. E.R. Heerdink. Utrecht University (Faculty of Science),6 Nov 2000. Read on Utrecht University Repository
Pharmacoepidemiologic risk evaluation in bone diseases Van Staa, T.P. Supervisory team: prof. dr. H.G.M. Leufkens, dr. C. Cooper. Utrecht University (Faculty of Science), 9 Jun 1999.
Studies on the quality of the pharmacolgical treatment of hypertension in the general population: Differences between women and men Klungel, O.H. Supervisory team: Prof. dr. A. Bakker, dr. A. de Boer, dr. A.H.P. Paes, dr. ir. J.C. Seidell. Utrecht University (Faculty of Science), 4 Mar 1999.
Blue Boy - why not? Studies of benzodiazepine use in a Dutch community Van Hulten, R.P. Supervisory team: prof. dr. A. Bakker, prof. dr. H.G.M. Leufkens, dr. K.B. Teeuw. Utrecht University (Faculty of Science), 1 Sept 1998.
Drug related problems in the elderly. Studies on occurrence and interventions Lau, H.S. Supervisory team: prof. dr. A.J. Porsius, dr. A. de Boer. Utrecht University (Faculty of Science), 2 Dec 1998.
Pharmacoepidemiologic approaches to the evaluation of antidepressant drugs Egberts, A.C.G. Supervisory team: prof. dr. A. Bakker, prof. dr. H.G.M. Leufkens, dr. G.H.P. de Koning. Utrecht University (Faculty of Science), 8 Oct 1997.
Developing patient education in community pharmacy. Blom, A.T.G. Supervisory team: Prof. dr. A. Bakker, prof. dr. G.J. Kok, dr. R. Jonkers Utrecht University (Faculty of Science), 7 Feb 1996.
Clustering of drug use in the elderly: population based studies into prevalence and outcomes Heerdink, E.R. Supervisory team: Prof. dr. A. Bakker, prof. dr. J. Glerum, dr. H.G.M. Leufkens. Utrecht University (Faculty of Science), 9 Oct 1995.
A Regionalized Spontaneous Surveillance Program for Adverse Drug Reactions as a Tool to Improve Pharmacotherapy De Koning, G.H.P. Supervisory team: Prof. dr. A. Bakker, prof. dr A.J. Porsius, dr. A. van der Kuy. Utrecht University (Faculty of Science), 24 Mar 1994.
PHARMO A record linkage system for postmarketing surveillance of prescription drugs in The Netherlands Herings, R.M.C. Supervisory team: Prof. dr. A. Bakker, prof. dr. F. Sturmans, dr. B.H.Ch. Stricker. Utrecht University (Faculty of Science), 16 Jun 1993
Altered vascular reactivity in hypertension and atherosclerosis. The role of the endothelium Riezebos, J. Supervisory team: Prof. dr. A.J. Porsius, dr. J. Wemer. Utrecht University (Faculty of Science), 9 Nov 1992.
Pharmacy records in Pharmacoepidemiology. Studies on antiinflammatory and antirheumatic drugs Leufkens, H.G.M. Supervisory team: Prof. dr. A. Bakker, dr. Y.A. Hekster. Utrecht University (Faculty of Science), 18 Oct 1990.
Apotheker en artsen in overleg? Paes, A.H.P. Supervisory team: Prof. dr. F.A. Nelemans, prof. dr. A. Bakker Utrecht University (Faculty of Science), 25 Apr 1989.
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